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150 records – page 1 of 15.

[A 40-year study of aortic and coronary artery atherosclerosis in male population of Yakutsk]

https://arctichealth.org/en/permalink/ahliterature76239
Source
Arkh Patol. 2006 Jan-Feb;68(1):6-10
Publication Type
Article
Author
O V Voronova
V S Zhdanov
V A Argunov
V P Alekseev
I E Galakhov
D V Iudakov
Source
Arkh Patol. 2006 Jan-Feb;68(1):6-10
Language
Russian
Publication Type
Article
Keywords
Adult
Aorta - pathology
Comparative Study
Coronary Arteriosclerosis - epidemiology - pathology
English Abstract
Health Transition
Humans
Male
Middle Aged
Retrospective Studies
Siberia
Urban Health - trends
Abstract
The trends in development of aortic and coronary atherosclerosis in healthy male population were studied by WHO methods in three trials: in 1963-1965, 1985-1987, 2001-2003. It was found that atherosclerosis and coronary arteries stenosis were less frequent in the native population of Yakutia than in migrants.
PubMed ID
16544527 View in PubMed
Less detail

Age-dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle-aged men: an autopsy study.

https://arctichealth.org/en/permalink/ahliterature201193
Source
Circulation. 1999 Aug 10;100(6):608-13
Publication Type
Article
Date
Aug-10-1999
Author
E. Ilveskoski
M. Perola
T. Lehtimäki
P. Laippala
V. Savolainen
J. Pajarinen
A. Penttilä
K H Lalu
A. Männikkö
K K Liesto
T. Koivula
P J Karhunen
Author Affiliation
Medical School, University of Tampere, Tampere University Hospital, Finland. ei46478@uta.fi
Source
Circulation. 1999 Aug 10;100(6):608-13
Date
Aug-10-1999
Language
English
Publication Type
Article
Keywords
Age Factors
Alcoholism - mortality
Alleles
Aorta, Abdominal - pathology
Aorta, Thoracic - pathology
Aortic Diseases - epidemiology
Apolipoprotein E3
Apolipoprotein E4
Apolipoproteins E - genetics
Arteriosclerosis - epidemiology - genetics - pathology
Autopsy
Body mass index
Cardiovascular Diseases - mortality
Cause of Death
Comorbidity
Coronary Artery Disease - epidemiology - genetics - pathology
Finland - epidemiology
Gene Frequency
Genetic Predisposition to Disease
Genotype
Heterozygote
Humans
Male
Middle Aged
Obesity - epidemiology
Violence
Abstract
Apolipoprotein E (apoE) polymorphism is one of the genetic determinants of serum cholesterol values. The apoE epsilon4 allele has been associated with advanced coronary heart disease (CHD) diagnosed by angiography, but the role of the apoE genotype in atherosclerosis has not been confirmed at vessel-wall level, nor is any age-dependent effect of the apoE genotype on the development of CHD known.
The right and left anterior descending coronary arteries (RCA and LAD) and the aorta from 700 male autopsy cases (Helsinki Sudden Death Study) in 1981-1982 and 1991-1992 (average age 53 years, range 33 to 70 years) were stained for fat, and all areas covered with fatty streaks, fibrotic plaques, and complicated lesions were measured. In the RCA and LAD, the apoE genotype was significantly associated with the area of total atherosclerotic lesions in men
PubMed ID
10441097 View in PubMed
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Alimentary lipemia, postprandial triglyceride-rich lipoproteins, and common carotid intima-media thickness in healthy, middle-aged men.

https://arctichealth.org/en/permalink/ahliterature10634
Source
Circulation. 1999 Aug 17;100(7):723-8
Publication Type
Article
Date
Aug-17-1999
Author
S. Boquist
G. Ruotolo
R. Tang
J. Björkegren
M G Bond
U. de Faire
F. Karpe
A. Hamsten
Author Affiliation
Atherosclerosis Research Unit, King Gustaf V Research Institute, Karolinska Hospital, Stockholm, Sweden.
Source
Circulation. 1999 Aug 17;100(7):723-8
Date
Aug-17-1999
Language
English
Publication Type
Article
Keywords
Alcohol drinking - epidemiology
Apolipoproteins B - blood
Apolipoproteins E - genetics
Area Under Curve
Arteriosclerosis - epidemiology - ultrasonography
Blood pressure
Body constitution
Carotid Artery, Common - ultrasonography - ultrastructure
Carotid Stenosis - epidemiology - ultrasonography
Chylomicrons - blood
Dietary Fats - pharmacokinetics
Eating - physiology
Fasting - blood
Genotype
Homeostasis
Humans
Insulin - blood
Lipids - blood
Lipoproteins - blood
Lipoproteins, LDL Cholesterol - blood
Lipoproteins, VLDL - blood
Male
Middle Aged
Proinsulin - blood
Reference Values
Research Support, Non-U.S. Gov't
Smoking - epidemiology
Sweden - epidemiology
Triglycerides - blood
Tunica Intima - ultrastructure
Abstract
BACKGROUND: Alimentary lipemia has been associated with coronary heart disease and common carotid artery intima-media thickness (IMT). This study was designed to investigate the relations of subclasses of postprandial triglyceride-rich lipoproteins (TRLs) with IMT. METHODS AND RESULTS: Ninety-six healthy 50-year-old men with an apolipoprotein (apo) E3/E3 genotype underwent an oral fat tolerance test and B-mode carotid ultrasound examination. The apo B-48 and apo B-100 contents of each fraction of TRLs were determined as a measure of chylomicron remnant and VLDL particle concentrations. In the fasting state, LDL cholesterol (P
PubMed ID
10449694 View in PubMed
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[Amputation and arterial reconstruction in the treatment of severe ischemia of the lower limbs. A survey covering all Danish hospitals during the period between 1 April 1931 and 31 December 1976].

https://arctichealth.org/en/permalink/ahliterature244275
Source
Ugeskr Laeger. 1981 Aug 3;143(32):2015-9
Publication Type
Article
Date
Aug-3-1981

Apolipoprotein E phenotypes and serum lipids in newborns and 3-year-old children: the Cardiovascular Risk in Young Finns Study.

https://arctichealth.org/en/permalink/ahliterature217182
Source
Pediatrics. 1994 Oct;94(4 Pt 1):489-93
Publication Type
Article
Date
Oct-1994
Author
T. Lehtimäki
K. Porkka
J. Viikari
C. Ehnholm
H K Akerblom
T. Nikkari
Author Affiliation
Department of Biomedical Sciences, University of Tampere, Finland.
Source
Pediatrics. 1994 Oct;94(4 Pt 1):489-93
Date
Oct-1994
Language
English
Publication Type
Article
Keywords
Adolescent
Age Factors
Alleles
Analysis of Variance
Apolipoprotein E2
Apolipoprotein E3
Apolipoprotein E4
Apolipoproteins E - genetics
Arteriosclerosis - epidemiology - etiology
Child
Child, Preschool
Cholesterol - blood
Cholesterol, LDL - blood
Enteral Nutrition
Female
Fetal Blood - chemistry
Finland - epidemiology
Follow-Up Studies
Humans
Infant, Newborn - blood
Male
Phenotype
Risk factors
Abstract
Apolipoprotein E (apoE) phenotype is a genetic determinant of plasma total cholesterol and low density lipoprotein (LDL) cholesterol concentrations, that are classical coronary heart disease risk factors. ApoE appears in three major isoforms E2, E3, and E4, coded by corresponding alleles epsilon 2, epsilon 3, and epsilon 4. These give rise to six different phenotypes.
To study the associations of apoE phenotype with cord serum lipids (during minimal enteral nutrition), and with serum lipids of 3-year-old children.
We determined serum lipid levels and apoE phenotypes in 206 newborns and 259 3-year-old children in connection with a larger follow-up study of atherosclerosis precursors in children and young adults. ApoE phenotyping was done directly from plasma by isoelectric focusing followed by immunoblotting.
The effect of apoE phenotype on serum total and LDL cholesterol was significantly different in newborns and 3-year-old children (two-way ANOVA, interaction between apoE phenotype and age group: P .05) either in males or in females. The mean serum levels of triglycerides and high density lipoprotein cholesterol did not differ between apoE phenotypes either in 3-year-old children or newborns.
The results show that the differences in serum total and LDL cholesterol levels between apoE phenotypes are formed after birth by the influence of environmental factors and suggest that both genetic and external factors influence the levels of serum cholesterol concentrations during the first years of life.
PubMed ID
7936857 View in PubMed
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Arterial compliance influences the measurement of flow-mediated vasodilation, but not acetylcholine-mediated forearm blood flow. The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study.

https://arctichealth.org/en/permalink/ahliterature82655
Source
Atherosclerosis. 2007 Jan;190(1):212-5
Publication Type
Article
Date
Jan-2007
Author
Lind Lars
Author Affiliation
Department of Medicine, Uppsala University Hospital and AstraZeneca R&D Mölndal, 751 85 Uppsala, Sweden. lars.lind@medsci.uu.se
Source
Atherosclerosis. 2007 Jan;190(1):212-5
Date
Jan-2007
Language
English
Publication Type
Article
Keywords
Acetylcholine - administration & dosage
Aged
Aging - physiology
Carotid Arteries - physiology
Compliance
Coronary Arteriosclerosis - epidemiology - physiopathology
Endothelium, Vascular - physiology
Forearm - blood supply
Humans
Prospective Studies
Regional Blood Flow - drug effects - physiology
Risk factors
Sweden - epidemiology
Sympathomimetics - administration & dosage
Terbutaline - administration & dosage
Vascular Resistance
Vasodilation - drug effects - physiology
Vasodilator Agents - administration & dosage
Abstract
OBJECTIVES: Flow-mediated vasodilation (FMD) is low even in healthy elderly and therefore relations between FMD and cardiovascular risk factors might be hard to evaluate in the elderly. Using data from the Prospective Study of the Vasculature in Uppsala Seniors (PIVUS) study, we investigated if a reduced arterial distensibility could influence FMD measurements. METHODS: In the population-based PIVUS study (1016 subjects aged 70), assessments of arterial distensibility by ultrasound in the carotid artery (CCA) and FMD were performed. Endothelium-dependent vasodilation was also evaluated with the invasive forearm technique with acetylcholine (EDV) and by pulse wave analysis following terbutaline injection. A poor CCA distensibility was defined as
PubMed ID
16530773 View in PubMed
Less detail
Source
Ugeskr Laeger. 1990 Sep 10;152(37):2641-3
Publication Type
Article
Date
Sep-10-1990
Author
M W Ingeman-Nielsen
Author Affiliation
Røntgenafdelingen, Aalborg Sygehus.
Source
Ugeskr Laeger. 1990 Sep 10;152(37):2641-3
Date
Sep-10-1990
Language
Danish
Publication Type
Article
Keywords
Adult
Aged
Aorta, Abdominal - pathology
Arteriosclerosis - epidemiology
Denmark - epidemiology
Female
Greenland - epidemiology
Humans
Male
Middle Aged
Abstract
X-ray examination of the lumbar spine of 268 Greenlanders and a corresponding number of Danes were reviewed in order to diagnose arteriosclerotic lesions of the abdominal aorta. In 10.4% of the Greenlanders and 11.6% of the Danes major calcifications were found. The two groups did not differ in distribution of age and sex of patients with arteriosclerotic lesions. It is known that arteriosclerotic complications occur less frequently in Greenlanders than in Danes. The study seems to indicate that this cannot be explained by a rarer occurrence of generalized arteriosclerosis.
PubMed ID
2219487 View in PubMed
Less detail
Source
Pathol Microbiol (Basel). 1967;30(5):805-9
Publication Type
Article
Date
1967

150 records – page 1 of 15.