Cefoxitin has been the prophylactic antibiotic of choice for appendectomy and colorectal surgery at this institution. Recent information suggests that cefazolin and metronidazole given as a single intravenous preparation could be a cost-effective alternative to cefoxitin or cefotetan for surgical antimicrobial prophylaxis of uncomplicated appendectomies. This study was conducted to determine the efficacy, toxicity, and cost of the current antibiotic regimens used for prophylaxis of uncomplicated appendectomies, to evaluate the efficacy, toxicity and cost of the cefazolin plus metronidazole combination in uncomplicated appendectomies, and to facilitate a cooperative working relationship between the Departments of Pharmacy and General Surgery. Although the numbers involved were small, this study suggests that the cefazolin/metronidazole combination is cost-effective. It is suggested that research is warranted in evaluating combinations such as this as cost-effective alternatives to current therapy.
Laparoscopic procedures are performed commonly in children. In general, the cost containment of laparoscopic surgery in children has not been evaluated.
To compare the costs of laparoscopic appendectomy with those of open appendectomy.
Prospective clinical trial between November 1, 1997, and April 30, 2000. For analysis, cost of supplies, operation room use, and recovery in the hospital and after discharge was evaluated. Costs common to both groups were not determined.
Operations performed in a university hospital.Patients Eighty-seven children aged 4 to 15 years who underwent appendectomy for suspected appendicitis. Patients were randomized to laparoscopic or open appendectomy. Intervention Laparoscopic appendectomies performed with the same standard set of reusable equipment.
Cost surplus of the laparoscopic procedure and recovery after surgery were evaluated, to determine the costs and effects of laparoscopic appendectomy compared with those of open appendectomy in children.
Excess operating and complication costs per procedure were 96 euros (EUR) in laparoscopic appendectomy. The increased operative expenses were offset by a shorter hospital stay, resulting in a marginal difference of 53 EUR in itemized total costs between the 2 procedures (total cost, 1023 EUR in the laparoscopic appendectomy group and 970 EUR in the open appendectomy group). After laparoscopic appendectomy, children returned to school and sports earlier than those who had had an open appendectomy.
Laparoscopic appendectomy was marginally more expensive, but it allowed earlier return to normal daily activities than open appendectomy.
Although elective outpatient surgery is commonplace, surgeons remain hesitant to discharge patients the same day after emergent surgery. We created a formal protocol to select patients for early discharge after laparoscopic appendectomy for acute appendicitis, and we assessed its safety and potential cost savings.
We matched patients who were discharged early from the recovery room with similar patients from a control group on the basis of age ± 3 years, presence or absence of a comorbidity, laparoscopic procedure, and nonperforated appendicitis; we compared them to assess the impact of early discharge on morbidity, return visits to the emergency room, and total cost incurred by our institution.
During the first year of our protocol, 72 of 161 (45%) patients who presented with acute appendicitis and underwent appendectomy were discharged early, with a median post-operative length of stay of 4.7 hours. When compared with matched controls, patients discharged early had similar complication rates (4.3% early group vs 7.1%, p = 0.72) and number of postoperative visits to the emergency room (11.4% vs 11.4%, p = 0.8), but had a reduced median length of stay (4.7 vs 16.2 hours, p