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Allergenic and immunogenic components of house dust mite, Dermatophagoides farinae.

https://arctichealth.org/en/permalink/ahliterature3845
Source
Ann Allergy. 1986 Feb;56(2):150-5
Publication Type
Article
Date
Feb-1986
Author
S. Nakada
M. Haida
T. Nakagawa
K. Ito
T. Miyamoto
Source
Ann Allergy. 1986 Feb;56(2):150-5
Date
Feb-1986
Language
English
Publication Type
Article
Keywords
Allergens
Animals
Antibodies, Anti-Idiotypic - analysis
Asthma - blood - immunology
Chromatography, Gel
Enzyme-Linked Immunosorbent Assay
Humans
Immunoglobulin G - immunology
Mice
Mice, Inbred BALB C
Mites - immunology
Research Support, Non-U.S. Gov't
Skin Tests
Tissue Extracts - isolation & purification
Abstract
The house dust mite, Dermatophagoides farinae, was fractionated by a Sephadex G-200 column. Its allergenic (IgE-reacting) and immunogenic (IgG-reacting) components were investigated. By means of skin test, the molecular weight (MW) of major allergenic components of mite was found to be approximately 9,000 to 21,000 daltons. Immunogenic components were investigated by enzyme linked immunosorbent assay using each fraction as an antigen and mice plasma and human serum as antibodies. With mouse plasma, high IgG antibody titers were observed in fractions that contained the part of the mite with high MW (greater than 150,000). With human sera, high IgG antibody titers were observed in fractions that contained the part of the mite with MW more than 30,000. Heterogeneity of human IgG antibody responses against mite antigen was also suggested.
PubMed ID
3484919 View in PubMed
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[Antigenic anachronism of the influenza A(H2N2) viruses in Leningrad in 1980. I. The epidemiological and serological characteristics of the influenzal infection caused by A/Leningrad/80 (H2N2) viruses].

https://arctichealth.org/en/permalink/ahliterature240308
Source
Zh Mikrobiol Epidemiol Immunobiol. 1984 Aug;(8):105-10
Publication Type
Article
Date
Aug-1984
Author
G I Karpukhin
T L Popova
L S Karpova
L M Tsybalova
G M Denisov
Source
Zh Mikrobiol Epidemiol Immunobiol. 1984 Aug;(8):105-10
Date
Aug-1984
Language
Russian
Publication Type
Article
Keywords
Acute Disease
Adolescent
Adult
Antibodies, Anti-Idiotypic - analysis
Antigens, Viral - analysis
Child
Child, Preschool
Disease Outbreaks - epidemiology
Female
Hemagglutination inhibition tests
Hemagglutinins, Viral - immunology
Humans
Infant
Influenza A Virus, H2N2 Subtype
Influenza A virus - immunology
Influenza B virus - immunology
Influenza, Human - epidemiology - immunology
Male
Respirovirus - immunology
Russia
Seasons
Urban Population
Abstract
In April-May 1980 a number of unrelated outbreaks of influenza-like diseases were registered in Leningrad in an infant home (50 out of 68 children under observation, aged 3 months to 2 years, were affected) and among the pupils of a boarding school (13 out of 50 adolescents under observation, aged 15-17 years, were affected). 5 strains of influenza A virus were isolated from 3 sick children and 1 clinically healthy child. A similar virus was isolated from a sick adolescent in a boarding school, as well as from a female patient aged 24 years at a domiciliary focus of infection (a sporadic case). In the subsequent laboratory investigation all these 7 strains were identified as viruses A/H2N2. Isolated cases of seroconversion to hemagglutinin H2 were definitely registered in 6 patients during February--May 1980. In 3 cases, including the 24-year old female patient with an acute respiratory disease, seroconversion to hemagglutinin H2 was observed in combination with the release of influenza viruses A/H2N2 from these patients. 2 influenza virus strains with this antigenic characteristic were isolated from a young female patient at an interval of 3 days. Among the patients admitted to the clinics of the Research Institute of Influenza in Leningrad on account of acute respiratory diseases isolated cases of diagnostically significant seroconversion to hemagglutinin H2 constituted 3.5% among children and 4.5% among adults. The study of the level of antihemagglutinins in the population revealed that in 1980 persons aged 18-50 years showed a high level of antihemagglutinins.(ABSTRACT TRUNCATED AT 250 WORDS)
PubMed ID
6091375 View in PubMed
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[Anti-influenza immunity and the prediction of influenza morbidity in the upcoming epidemic season].

https://arctichealth.org/en/permalink/ahliterature241979
Source
Vopr Virusol. 1983 May-Jun;(3):290-2
Publication Type
Article
Author
A N Slepushkin
G I Fedorova
N S Popova
E I Mel'nichenko
Source
Vopr Virusol. 1983 May-Jun;(3):290-2
Language
Russian
Publication Type
Article
Keywords
Adolescent
Adult
Antibodies, Anti-Idiotypic - analysis
Antibodies, Viral - analysis
Antibody formation
Disease Outbreaks - epidemiology
Humans
Influenza A virus - immunology
Influenza, Human - epidemiology - immunology
Middle Aged
Moscow
Prognosis
Seasons
Abstract
The possibility of practical use of an increase in the level of antibody to a future causative agent of epidemic from minimal to the "critical" level in the human population against the background of a relative epidemic-free state in a town as a prepotent of an epidemic increase of influenza incidence was studied. During 4 spring and 3 autumn seasons (1978--1981) titres of antihemagglutinins to influenza A (H3N2) and B viruses were determined in 200--250 blood serum specimens from residents of Moscow selected with similar age distribution for each season against a working reference human serum. From the analysis of the antibody dynamics influenza A (H3N2) epidemic in 1979 and influenza B epidemic in 1980 were timely prognosed.
PubMed ID
6604366 View in PubMed
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Clinical experience with a new apheresis filter that specifically depletes ABO blood group antibodies.

https://arctichealth.org/en/permalink/ahliterature80718
Source
Transfusion. 2006 Sep;46(9):1568-75
Publication Type
Article
Date
Sep-2006
Author
Kumlien Gunilla
Ullström Lisbeth
Losvall Anita
Persson Lars-Gunnar
Tydén Gunnar
Author Affiliation
Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Huddinge, SE-141 86 Stockholm, Sweden. gunilla.kumlien@karolinska.se
Source
Transfusion. 2006 Sep;46(9):1568-75
Date
Sep-2006
Language
English
Publication Type
Article
Keywords
ABO Blood-Group System - blood - immunology
Antibodies, Anti-Idiotypic - analysis
Antibodies, Monoclonal - administration & dosage - immunology - pharmacology
Blood Component Removal - instrumentation - methods
Blood Group Incompatibility - blood - immunology
Follow-Up Studies
Humans
Immunosorbent Techniques
Immunosuppressive Agents - therapeutic use
Infant
Kidney Transplantation - immunology
Living Donors
Time Factors
Transplantation, Homologous
Treatment Outcome
Abstract
BACKGROUND: Although living kidney donors are increasingly being used, in most centers, 30 to 40 percent of potential donors are being turned down due to ABO mismatch. A protocol for ABO-mismatched kidney transplantation without splenectomy and with antigen-specific adsorption of ABO antibodies instead of nonspecific plasmapheresis was therefore designed. STUDY DESIGN AND METHODS: The immunosuppressive protocol used at the Department of Transplantation Surgery, Karolinska University Hospital, Stockholm, Sweden, together with relevant clinical data for 11 of the studied patients, have been described previously. The protocol called for immunoadsorption of ABO antibodies on Days -6, -5, -2, and -1 and on Days +2, +5, and +8. Patient plasma was recirculated through a new apheresis filter, the Glycosorb ABO column (Glycorex Transplantation AB), containing synthetic terminal trisaccharide A or B blood group antigen linked to a Sepharose matrix. RESULTS: Since 2001, 15 patients, including 2 infants, have been successfully transplanted with ABO-mismatched kidneys from living donors. The donor-recipient blood groups were A1-O (n = 5), A2-O (n = 2), B-O (n = 4), B-A (n = 2), and A1B-B (n = 2). ABO antibody titers at transplantation did not exceed immunoglobulin G 4 or immunoglobulin M 4 levels. No humoral rejections and no late rebound of ABO antibodies were observed. No adverse effects related to immunoadsorption treatment have been recorded. CONCLUSION: It is concluded that ABO-mismatched kidney transplantations can be successfully performed without splenectomy and that ABO antibodies can be effectively and safely depleted with the Glycosorb ABO column.
PubMed ID
16965585 View in PubMed
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[Dynamics of population immunity to influenza A and B viruses resulting from the introduction of a comprehensive influenza control system in a city].

https://arctichealth.org/en/permalink/ahliterature240793
Source
Zh Mikrobiol Epidemiol Immunobiol. 1984 Mar;(3):103-6
Publication Type
Article
Date
Mar-1984
Author
Iu G Kustikova
V M Gagarinova
Source
Zh Mikrobiol Epidemiol Immunobiol. 1984 Mar;(3):103-6
Date
Mar-1984
Language
Russian
Publication Type
Article
Keywords
Adolescent
Antibodies, Anti-Idiotypic - analysis
Antibodies, Viral - analysis
Child
Child, Preschool
Humans
Immunity
Influenza A virus - immunology
Influenza Vaccines - administration & dosage
Influenza, Human - immunology - prevention & control
Orthomyxoviridae - immunology
Russia
Seasons
Urban Population
Abstract
The time course of population immunity to influenza viruses A and B in different social and age groups among the inhabitants of Severodvinsk before and after the introduction of the complex system of influenza control has been studied. The influence of mass vaccinal prophylaxis and natural influenza morbidity on population immunity among the inhabitants of the city is shown.
PubMed ID
6233829 View in PubMed
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[Effectiveness of the seroprophylaxis of tick-borne encephalitis depending on the titer of homologous gamma-globulin antihemagglutinins].

https://arctichealth.org/en/permalink/ahliterature235056
Source
Zh Mikrobiol Epidemiol Immunobiol. 1987 Jul;(7):32-4
Publication Type
Article
Date
Jul-1987
Author
L A Khlebutina
V M Minaeva
P M Luzin
N V Kipriianova
A G Shamarina
Source
Zh Mikrobiol Epidemiol Immunobiol. 1987 Jul;(7):32-4
Date
Jul-1987
Language
Russian
Publication Type
Article
Keywords
Antibodies, Anti-Idiotypic - analysis
Disease Reservoirs
Drug Evaluation
Encephalitis, Tick-Borne - epidemiology - immunology - prevention & control
Humans
Immunization, Passive
Rural Population
Russia
gamma-Globulins - immunology
Abstract
To give a rationale for using homologous gamma globulin with antihemagglutinin titers of 1 : 20 to 1 : 80 for the prophylaxis of tick-borne encephalitis, 5-year observations covering all persons attacked by ticks in one of the intensive natural foci of the disease in the Western Urals have been made. The threefold statistically significant difference in the morbidity rate of tick-borne encephalitis between groups of persons immunized and not immunized with gamma globulin has been shown.
PubMed ID
2445130 View in PubMed
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Evaluation of four commercial enzyme immunoassays for detection of immunoglobulin M antibodies to human parvovirus B19.

https://arctichealth.org/en/permalink/ahliterature34662
Source
Eur J Clin Microbiol Infect Dis. 1996 Sep;15(9):758-61
Publication Type
Article
Date
Sep-1996
Author
T. Sloots
P L Devine
Author Affiliation
Sir Albert Sakzewski Virus Research Centre, Herston, Queensland, Australia.
Source
Eur J Clin Microbiol Infect Dis. 1996 Sep;15(9):758-61
Date
Sep-1996
Language
English
Publication Type
Article
Keywords
Antibodies, Anti-Idiotypic - analysis
Australia
Child, Preschool
Comparative Study
Erythema Infectiosum - diagnosis - immunology
Evaluation Studies
Female
Fluorescent Antibody Technique, Indirect
Humans
Immunoenzyme Techniques
Immunoglobulin M
Male
Parvovirus B19, Human - immunology - isolation & purification
Polymerase Chain Reaction
Sensitivity and specificity
Abstract
Four commercial enzyme immunoassays (EIAs) for the detection of parvovirus B19-specific immunoglobulin M (IgM) antibodies [Biotrin Parvovirus B19 IgM (Biotrin International, Ireland); Parvoscan B19 IgM (Euro-Diagnostica, Sweden); Parvovirus IgM (Immunobiological Laboratories [IBL], Germany); and human parvovirus B19 IgM (Hillcrest Biologicals, USA)] were compared to indirect immunofluorescence assay (IFA) and polymerase chain reaction (PCR). Using IFA as the reference test, high sensitivities (> or = 97%) were observed with all four EIAs, though the specificities of the Biotrin and IBL EIAs (99% and 96% respectively) were significantly higher than those of the Hillcrest and Euro-Diagnostica EIAs (81% and 79% respectively).
PubMed ID
8922581 View in PubMed
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Gm allotypes in Swedish myasthenia gravis patients.

https://arctichealth.org/en/permalink/ahliterature26956
Source
J Immunogenet. 1983 Feb;10(1):1-9
Publication Type
Article
Date
Feb-1983
Author
C I Smith
R. Grubb
L. Hammarström
G. Matell
Source
J Immunogenet. 1983 Feb;10(1):1-9
Date
Feb-1983
Language
English
Publication Type
Article
Keywords
Antibodies, Anti-Idiotypic - analysis
Autoantibodies - genetics
Gene Frequency
HLA Antigens - genetics
Humans
Immunoglobulin Allotypes - genetics
Myasthenia Gravis - genetics - immunology
Phenotype
Receptors, Cholinergic - immunology
Research Support, Non-U.S. Gov't
Sweden - ethnology
Thymoma - genetics - immunology
Abstract
Gm phenotype frequencies were examined in 112 Swedish myasthenia gravis patients. The G1m 1,2,3 phenotype frequency in the total patient material did not differ significantly from that found in the normal population. However, when patients were subdivided, three different patient groups were observed with regard to Gm1 frequency: (1) Thymoma patients having a low frequency of Gm1, (2) Non-thymoma patients with a mild disease having a low frequency of Gm1 and (3) Non-thymoma patients with a severe disease having a high frequency of Gm1. When patients were subdivided according to presence or absence of HLA-B8 and Gm1 respectively, severe symptoms were less frequent in the HLA-B8+, Gm(-1) group as compared to the HLA-B8+, Gm(+1) group. Furthermore, there was an increased frequency of sera with anti-immunoglobulins not inhibitable by pooled control immunoglobulins.
PubMed ID
6601678 View in PubMed
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[Humoral immunity to influenza A and B viruses in the blood sera of children younger than 14 in 1981].

https://arctichealth.org/en/permalink/ahliterature241624
Source
Vopr Virusol. 1983 Sep-Oct;28(5):564-7
Publication Type
Article
Author
A N Slepushkin
V V Ritova
G I Fedorova
L V Feklisova
N P Obrosova-Serova
Source
Vopr Virusol. 1983 Sep-Oct;28(5):564-7
Language
Russian
Publication Type
Article
Keywords
Adolescent
Antibodies, Anti-Idiotypic - analysis
Antibodies, Viral - analysis
Antibody formation
Antibody Specificity
Child
Humans
Influenza A virus - immunology
Moscow
Orthomyxoviridae - immunology
Seasons
Urban Population
Abstract
Blood sera from 317 children with the history of noninfectious diseases or normal children pretreated with RDE were collected and examined for antihemagglutinins to 7 influenza virus strains in order to check the results of studies of 1980 and to study the immunity status to influenza A (H1N1), A (H2N2), A (H3N2) and B in the preepidemic period of 1981. Negative results of antihemagglutinin detection to influenza A/Iksha/1/57 (H2N2) in sera of all the children have confirmed the conclusion made in the previous paper (1) that influenza A (H1N2) viruses have not circulated in recent years among the population of Moscow City and suburban areas. Fourteen sera positive in HI tests with A/Shklyawer/49 virus similar to A/PR/8/34 (H1N1) in titres from 1:20 to 1:40 did not produce hemolysis zones with A/PR/8/34 virus in RHT, but most of these sera gave similar results of both tests with A/Brazil/11/79 and A/Khabarovsk/1/77 viruses. This attests to cross, nonspecific nature of hemagglutination-inhibition with A/Shklyawer/49 virus which evidently does not circulate now in the population of Moscow City and suburbs. An increase in the level of immunity to influenza B and A (H1N1)/1977 viruses reflected the epidemic situation of the previous year.
PubMed ID
6606903 View in PubMed
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Immune complexes with antiglobulin activity in sera of Moloney sarcoma-bearing rats.

https://arctichealth.org/en/permalink/ahliterature27065
Source
Clin Exp Immunol. 1982 Apr;48(1):70-8
Publication Type
Article
Date
Apr-1982
Author
J R Balint
Source
Clin Exp Immunol. 1982 Apr;48(1):70-8
Date
Apr-1982
Language
English
Publication Type
Article
Keywords
Animals
Antibodies, Anti-Idiotypic - analysis
Antigen-Antibody Complex - analysis - isolation & purification
Cell Line
Chemical Fractionation
Immunoglobulin G - metabolism
Immunoglobulin M - metabolism
Models, Biological
Molecular Weight
Moloney murine leukemia virus - immunology
Ovalbumin - analysis
Rabbits
Rats
Rats, Inbred BN
Rats, Inbred Lew
Research Support, U.S. Gov't, P.H.S.
Sarcoma, Experimental - immunology
Abstract
Immune complexes (IC) were detected and isolated from the serum of Brown Norway (BN), (Lewis x BN)F1, and Lewis rats bearing a Moloney sarcoma (MST). IC were isolated from the serum of individual rats employing a system of G-200 chromatography and passage through a heavy chain specific anti-rat IgG Immunoadsorbent. IgG and IgM were identified in the isolated IC by polyacrylamide gel electrophoresis (PAGE) and co-precipitation radioimmunoassays. Employing monospecific antibodies, IC consisting of IgG and IgM were bound to Raji cells as assessed by radioimmunoassay and indirect immunofluorescence. Raji binding activity of IC-containing serum was substantially reduced by pretreatment with dithiothreitol or incubation with anti-rat IgM or pooled normal rat IgG: F(ab')2. Sucrose density gradient ultracentrifugation under acid conditions dissociated IC into 7S IgG and 19S IgM components which recombined when co-incubated at pH 7 . 5. Viral antigens (gp70 and p30) were not detected in IC by PAGE and co-precipitation radioimmunoassay. Findings show that sera of rats bearing MST contain IC consisting predominantly of immunoglobulin. An IgM component which was separated, isolated and identified within IC containing serum displays anti-F(ab')2 reactivity.
PubMed ID
6979450 View in PubMed
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18 records – page 1 of 2.