Skip header and navigation

Refine By

388 records – page 1 of 39.

2-year patient-related versus stent-related outcomes: the SORT OUT IV (Scandinavian Organization for Randomized Trials With Clinical Outcome IV) Trial.

https://arctichealth.org/en/permalink/ahliterature120892
Source
J Am Coll Cardiol. 2012 Sep 25;60(13):1140-7
Publication Type
Article
Date
Sep-25-2012
Author
Lisette Okkels Jensen
Per Thayssen
Evald Høj Christiansen
Hans Henrik Tilsted
Michael Maeng
Knud Nørregaard Hansen
Anne Kaltoft
Henrik Steen Hansen
Hans Erik Bøtker
Lars Romer Krusell
Jan Ravkilde
Morten Madsen
Leif Thuesen
Jens Flensted Lassen
Author Affiliation
Department of Cardiology, Odense University Hospital, Odense, Denmark. okkels@dadlnet.dk
Source
J Am Coll Cardiol. 2012 Sep 25;60(13):1140-7
Date
Sep-25-2012
Language
English
Publication Type
Article
Keywords
Aged
Angioplasty, Balloon, Coronary
Coronary Artery Disease - mortality - therapy
Death
Denmark
Drug-Eluting Stents
Female
Follow-Up Studies
Humans
Immunosuppressive Agents - therapeutic use
Male
Middle Aged
Myocardial Infarction - etiology
Myocardial Revascularization - statistics & numerical data
Single-Blind Method
Sirolimus - adverse effects - analogs & derivatives - therapeutic use
Thrombosis - etiology
Treatment Outcome
Abstract
There are limited head-to-head randomized data on patient-related versus stent-related outcomes for everolimus-eluting stents (EES) and sirolimus-eluting stents (SES).
In the SORT OUT IV (Scandinavian Organization for Randomized Trials With Clinical Outcome IV) trial, comparing the EES with the SES in patients with coronary artery disease, the EES was noninferior to the SES at 9 months.
The primary endpoint was a composite: cardiac death, myocardial infarction (MI), definite stent thrombosis, or target vessel revascularization. Safety and efficacy outcomes at 2 years were further assessed with specific focus on patient-related composite (all death, all MI, or any revascularization) and stent-related composite outcomes (cardiac death, target vessel MI, or symptom-driven target lesion revascularization). A total of 1,390 patients were assigned to receive the EES, and 1,384 patients were assigned to receive the SES.
At 2 years, the composite primary endpoint occurred in 8.3% in the EES group and in 8.7% in the SES group (hazard ratio [HR]: 0.94, 95% confidence interval [CI]: 0.73 to 1.22). The patient-related outcome: 15.0% in the EES group versus 15.6% in the SES group, (HR: 0.95, 95% CI: 0.78 to 1.15), and the stent-related outcome: 5.2% in the EES group versus 5.3% in the SES group (HR: 0.97, 95% CI: 0.70 to 1.35) did not differ between groups. Rate of definite stent thrombosis was lower in the EES group (0.2% vs. 0.9%, (HR: 0.23, 95% CI: 0.07 to 0.80).
At 2-year follow-up, the EES was found to be noninferior to the SES with regard to both patient-related and stent-related clinical outcomes.
PubMed ID
22958957 View in PubMed
Less detail

7,528 patients treated with PCI--a Scandinavian real-life scenario.

https://arctichealth.org/en/permalink/ahliterature160536
Source
Cardiology. 2008;110(2):96-105
Publication Type
Article
Date
2008
Author
Sune Pedersen
Søren Galatius
Jan Bech
Erik Jørgensen
Kari Saunamaki
Steffen Helqist
Jan Skov Jensen
Henning Kelbaek
Jan Kyst Madsen
Author Affiliation
Cardiac Catheterisation Laboratory, Heart Clinic, Copenhagen, Denmark. sunped01@geh.regionh.dk
Source
Cardiology. 2008;110(2):96-105
Date
2008
Language
English
Publication Type
Article
Keywords
Angioplasty, Balloon, Coronary - statistics & numerical data
Coronary Angiography
Coronary Artery Disease - epidemiology - radiography - therapy
Female
Humans
Male
Middle Aged
Retrospective Studies
Risk factors
Scandinavia
Stents - statistics & numerical data
Abstract
Analyze clinical, temporal and procedural characteristics from 7,528 consecutive percutaneous coronary intervention (PCI) patients in one of the largest published contemporary European PCI-database during a 6-year period.
Retrospective study design.
1998-2004. Temporal and referral changes in a Danish PCI-registry were analyzed. Demographic and angiographic variables were compared with data from randomized clinical trials, US-registries and current guidelines.
22,214 patients were examined with coronary angiography and 7,528 patients were treated with PCI. The annual number of PCI's increased by 15%. Over time, the fraction of patients with risk factors increased, median age increased from 61 to 64 years and the coronary pathology was significantly worsened. ST-elevation myocardial infarction patients primarily admitted to hospitals without facilities for primary angioplasty, were less likely to receive primary PCI. Baseline-data were in general in par with randomized clinical trial study populations and large-scale US data-registries. Interestingly, 14% of all PCI-procedures were performed on patients with a clinical presentation, for which coronary artery bypass grafting would be recommended by guidelines.
PCI is performed in an increasingly sicker population, but generally in accordance with randomized trials and similar to US tradition. However, 14% were treated with PCI even though coronary artery bypass grafting was recommended by guidelines.
PubMed ID
17971658 View in PubMed
Less detail

[35-year practice of treatment of acute coronary syndrome in 3rd central military clinical hospital n. a. A.A.Vishnevsky].

https://arctichealth.org/en/permalink/ahliterature137718
Source
Voen Med Zh. 2010 Oct;331(10):18-27
Publication Type
Article
Date
Oct-2010
Author
S A Beliakin
A A Prokhorchik
Source
Voen Med Zh. 2010 Oct;331(10):18-27
Date
Oct-2010
Language
Russian
Publication Type
Article
Keywords
Acute Coronary Syndrome - diagnosis - therapy
Angioplasty, Balloon, Coronary
Coronary Artery Bypass
Fibrinolytic Agents - administration & dosage
Hospitals, Military
Humans
Retrospective Studies
Russia
Abstract
Results of 35-years clinical investigation on acute coronary syndrome performed in the 3rd Central military clinical hospital named after A.A. Vishnevsky are presented. Research topics are the following: pathways of blood coagulation alterations,lipid metabolism, improving drug management of ischemic heart disease exacerbations, new medical technologies in diagnostics and treatment of acute coronary syndrome. Decision procedure in patient with acute coronary syndrome was developed in the Hospital. Criteria for percutaneous coronary interventions and coronary artery bypass surgery were elaborated. Original scale for death and cardiac complications risk assessment in patients with acute myocardial infarction undergoing coronary artery stenting was developed. According to the scale, differential scheme of antiplatelet therapy was introduced, and its implementation resulted in decrease of complications rate. Advantage of early invasive strategy vs. conservative approach was proven.
PubMed ID
21254581 View in PubMed
Less detail

The ability to achieve complete revascularization is associated with improved in-hospital survival in cardiogenic shock due to myocardial infarction: Manitoba cardiogenic SHOCK Registry investigators.

https://arctichealth.org/en/permalink/ahliterature134718
Source
Catheter Cardiovasc Interv. 2011 Oct 1;78(4):540-8
Publication Type
Article
Date
Oct-1-2011
Author
Farrukh Hussain
Roger K Philipp
Robin A Ducas
Jason Elliott
Vladimír Džavík
Davinder S Jassal
James W Tam
Daniel Roberts
Philip J Garber
John Ducas
Author Affiliation
Section of Cardiology Dept. of Cardiac Sciences, University of Manitoba, Winnipeg, Manitoba, Canada. fhussain@sbgh.mb.ca
Source
Catheter Cardiovasc Interv. 2011 Oct 1;78(4):540-8
Date
Oct-1-2011
Language
English
Publication Type
Article
Keywords
Aged
Angioplasty, Balloon, Coronary - adverse effects - mortality
Cardiovascular Agents - adverse effects - therapeutic use
Catheterization, Swan-Ganz
Coronary Angiography
Coronary Artery Bypass - adverse effects - mortality
Female
Hospital Mortality
Humans
Logistic Models
Male
Manitoba
Middle Aged
Myocardial Infarction - complications - diagnosis - mortality - therapy
Odds Ratio
Patient Discharge - statistics & numerical data
Registries
Retrospective Studies
Risk assessment
Risk factors
Shock, Cardiogenic - diagnosis - etiology - mortality - therapy
Survival Analysis
Survival Rate
Time Factors
Treatment Outcome
Abstract
To identify predictors of survival in a retrospective multicentre cohort of patients with cardiogenic shock undergoing coronary angiography and to address whether complete revascularization is associated with improved survival in this cohort.
Early revascularization is the standard of care for cardiogenic shock. Coronary bypass grafting and percutaneous intervention have complimentary roles in achieving this revascularization.
A total of 210 consecutive patients (mean age 66 ± 12 years) at two tertiary centres from 2002 to 2006 inclusive with a diagnosis of cardiogenic shock were evaluated. Univariate and multivariate predictors of in-hospital survival were identified utilizing logistic regression.
ST elevation infarction occurred in 67% of patients. Thrombolysis was administered in 34%, PCI was attempted in 62% (88% stented, 76% TIMI 3 flow), CABG was performed in 22% (2.7 grafts, 14 valve procedures), and medical therapy alone was administered to the remainder. The overall survival to discharge was 59% (CABG 68%, PCI 57%, medical 48%). Independent predictors of mortality included complete revascularization (P = 0.013, OR = 0.26 (95% CI: 0.09-0.76), hyperlactatemia (P = 0.046, OR = 1.14 (95% CI: 1.002-1.3) per mmol increase), baseline renal insufficiency (P = 0.043, OR = 3.45, (95% CI: 1.04-11.4), and the presence of anoxic brain injury (P = 0.008, OR = 8.22 (95% CI: 1.73-39.1). Within the STEMI with concomitant multivessel coronary disease subgroup of this population (N = 101), independent predictors of survival to discharge included complete revascularization (P = 0.03, OR = 2.5 (95% CI: 1.1-6.2)) and peak lactate (P = 0.02).
The ability to achieve complete revascularization may be strongly associated with improved in-hospital survival in patients with cardiogenic shock.
Notes
Comment In: Catheter Cardiovasc Interv. 2011 Oct 1;78(4):549-5021953751
PubMed ID
21547996 View in PubMed
Less detail

Absence of bias against smokers in access to coronary revascularization after cardiac catheterization.

https://arctichealth.org/en/permalink/ahliterature176495
Source
Int J Qual Health Care. 2005 Feb;17(1):37-42
Publication Type
Article
Date
Feb-2005
Author
Jacques Cornuz
Peter D Faris
P Diane Galbraith
Merril L Knudtson
William A Ghali
Author Affiliation
Department of Medicine, University of Lausanne, Lausanne, Switzerland.
Source
Int J Qual Health Care. 2005 Feb;17(1):37-42
Date
Feb-2005
Language
English
Publication Type
Article
Keywords
Alberta - epidemiology
Angioplasty, Balloon, Coronary - utilization
Attitude of Health Personnel
Cardiac Catheterization - utilization
Cohort Studies
Coronary Artery Bypass - utilization
Coronary Disease - diagnosis - therapy
Female
Humans
Male
Middle Aged
Myocardial Revascularization - utilization
Prejudice
Prospective Studies
Smoking - epidemiology
Abstract
Many consider smoking to be a personal choice for which individuals should be held accountable. We assessed whether there is any evidence of bias against smokers in cardiac care decision-making by determining whether smokers were as likely as non-smokers to undergo revascularization procedures after cardiac catheterization.
Prospective cohort study. Subjects and setting. All patients undergoing cardiac catheterization in Alberta, Canada.
Patients were categorized as current smokers, former smokers, or never smokers, and then compared for their risk-adjusted likelihood of undergoing revascularization procedures (percutaneous coronary intervention or coronary artery bypass grafting) after cardiac catheterization.
Among 20406 patients undergoing catheterization, 25.4% were current smokers at the time of catheterization, 36.6% were former smokers, and 38.0% had never smoked. When compared with never smokers (reference group), the hazard ratio for undergoing any revascularization procedure after catheterization was 0.98 (95% CI 0.93-1.03) for current smokers and 0.98 (0.94-1.03) for former smokers. The hazard ratio for undergoing coronary artery bypass grafting was 1.09 (1.00-1.19) for current smokers and 1.00 (0.93-1.08) for former smokers. For percutaneous coronary intervention, the hazard ratios were 0.93 (0.87-0.99) for current smokers and 1.00 (0.94-1.06) for former smokers.
Despite potential for discrimination on the basis of smoking status, current and former smokers undergoing cardiac catheterization in Alberta, Canada were as likely to undergo revascularization procedures as catheterization patients who had never smoked.
PubMed ID
15668309 View in PubMed
Less detail

Access to myocardial revascularization procedures: closing the gap with time?

https://arctichealth.org/en/permalink/ahliterature170348
Source
BMC Public Health. 2006;6:60
Publication Type
Article
Date
2006
Author
Alain Vanasse
Théophile Niyonsenga
Josiane Courteau
Abbas Hemiari
Author Affiliation
Family Medicine Department, Faculty of Medicine, Université de Sherbrooke, Sherbrooke (QC), J1H 5N4, Canada. alain.vanasse@usherbrooke.ca
Source
BMC Public Health. 2006;6:60
Date
2006
Language
English
Publication Type
Article
Keywords
Adult
Aged
Angioplasty, Balloon, Coronary - utilization
Cardiac Care Facilities - supply & distribution
Cohort Studies
Coronary Artery Bypass - utilization
Female
Geography
Health Services Accessibility - statistics & numerical data
Humans
Incidence
Male
Middle Aged
Myocardial Infarction - epidemiology - surgery
Myocardial Revascularization - utilization
Patient Discharge
Quebec - epidemiology
Registries
Time Factors
Abstract
Early access to revascularization procedures is known to be related to a more favorable outcome in myocardial infarction (MI) patients, but access to specialized care varies widely amongst the population. We aim to test if the early gap found in the revascularization rates, according to distance between patients' location and the closest specialized cardiology center (SCC), remains on a long term basis.
We conducted a population-based cohort study using data from the Quebec's hospital discharge register (MED-ECHO). The study population includes all patients 25 years and older living in the province of Quebec, who were hospitalized for a MI in 1999 with a follow up time of one year after the index hospitalization. The main variable is revascularization (percutaneous transluminal coronary angioplasty or a coronary artery bypass graft). The population is divided in four groups depending how close they are from a SCC ( or = 105 km). Revascularization rates are adjusted for age and sex.
The study population includes 11,802 individuals, 66% are men. The one-year incidence rate of MI is 244 individuals per 100,000 inhabitants. At index hospitalization, a significant gap is found between patients living close ( or = 32 km). During the first year, a gap reduction can be observed but only for patients living at an intermediate distance from the specialized center (64-105 km).
The gap observed in revascularization rates at the index hospitalization for MI is in favour of patients living closer (
Notes
Cites: Can J Cardiol. 1999 Nov;15(11):1277-8210579743
Cites: BMC Cardiovasc Disord. 2005;5(1):2116008836
Cites: Chronic Dis Can. 2000;21(3):104-1311082346
Cites: Med Care. 2001 May;39(5):446-5811317093
Cites: Eur Heart J. 2001 Sep;22(18):1702-1511511120
Cites: JAMA. 2002 Mar 13;287(10):1269-7611886318
Cites: Aust J Rural Health. 2000 Dec;8(6):310-711894790
Cites: Med Care. 2002 Jul;40(7):614-2612142777
Cites: J Gen Intern Med. 2002 Aug;17(8):604-1112213141
Cites: CMAJ. 2003 Feb 4;168(3):261-412566329
Cites: Ann Med. 2003;35(1):43-5012693612
Cites: Can J Cardiol. 2003 Jun;19(7):774-8112813610
Cites: Can J Cardiol. 2002 Oct;18(10):1067-7612420042
Cites: Can J Cardiol. 2003 Jun;19(7):782-912813611
Cites: Can J Cardiol. 2003 Jul;19(8):893-90112876609
Cites: Am Heart J. 2003 Aug;146(2):242-912891191
Cites: Can J Cardiol. 2003 Sep;19(10):1123-3114532937
Cites: Can J Cardiol. 2003 Oct;19(11):1241-814571309
Cites: Can J Cardiol. 2004 Jan;20(1):61-714968144
Cites: Can J Cardiol. 2004 Mar 1;20(3):282-9115054505
Cites: Can J Cardiol. 2004 Mar 15;20(4):391-715057314
Cites: Can J Cardiol. 2004 Apr;20(5):491-50015100750
Cites: Arch Intern Med. 1995 Feb 13;155(3):318-247832604
Cites: N Engl J Med. 1995 Aug 31;333(9):565-727623907
Cites: Med Care Res Rev. 1995 Nov;52(4):532-4210153313
Cites: Am J Cardiol. 1997 Sep 15;80(6):777-99315589
Cites: J Am Coll Cardiol. 1997 Nov 1;30(5):1187-929350913
Cites: Stroke. 1998 Nov;29(11):2304-109804638
Cites: Int J Cardiol. 1999 Jan;68(1):63-710077402
Cites: J Am Coll Cardiol. 1999 Sep;34(3):890-91110483976
Cites: J Gen Intern Med. 1999 Sep;14(9):555-810491245
Cites: Can J Cardiol. 2005 Mar;21(3):247-5515776114
Cites: J Epidemiol Community Health. 2000 Apr;54(4):293-810827912
PubMed ID
16524458 View in PubMed
Less detail

Achieving optimal care for ST-segment elevation myocardial infarction in Canada.

https://arctichealth.org/en/permalink/ahliterature162934
Source
CMAJ. 2007 Jun 19;176(13):1843-4
Publication Type
Article
Date
Jun-19-2007
Author
Andrew Travers
Author Affiliation
Emergency Health Services Nova Scotia, Dartmouth, NS. traverah@gov.ns.ca
Source
CMAJ. 2007 Jun 19;176(13):1843-4
Date
Jun-19-2007
Language
English
Publication Type
Article
Keywords
Angioplasty, Balloon, Coronary
Canada
Critical Pathways
Electrocardiography
Emergency Medical Services - standards - utilization
Fibrinolytic Agents - therapeutic use
Humans
Myocardial Infarction - drug therapy - therapy
Notes
Cites: Acad Emerg Med. 2006 Jan;13(1):84-916365334
Cites: Eur Heart J. 2003 Jan;24(1):28-6612559937
Cites: Circulation. 2003 Dec 9;108(23):2851-614623806
Cites: Can J Cardiol. 2004 Sep;20(11):1075-915457302
Cites: CMAJ. 2007 Jun 19;176(13):1833-817576980
Cites: Eur Heart J. 2006 May;27(10):1146-5216624832
Cites: Eur Heart J. 2006 Jul;27(13):1530-816757491
Cites: N Engl J Med. 2006 Nov 30;355(22):2308-2017101617
Comment On: CMAJ. 2007 Jun 19;176(13):1833-817576980
PubMed ID
17576982 View in PubMed
Less detail

[Acute myocardial infarction after snow removal].

https://arctichealth.org/en/permalink/ahliterature175912
Source
Duodecim. 2005;121(2):181-3
Publication Type
Article
Date
2005

Acute myocardial infarction in Alberta: temporal changes in outcomes, 1994 to 1999.

https://arctichealth.org/en/permalink/ahliterature181191
Source
Can J Cardiol. 2004 Feb;20(2):213-9
Publication Type
Article
Date
Feb-2004
Author
Hude Quan
Bibiana Cujec
Yan Jin
David Johnson
Author Affiliation
Department of Community Health Sciences, Centre for Health and Policy Studies, University of Calgary, Quality Improvement and Health Information, Calgary Health Region, Alberta. hquan@ucalgary.ca
Source
Can J Cardiol. 2004 Feb;20(2):213-9
Date
Feb-2004
Language
English
Publication Type
Article
Keywords
Adrenergic beta-Antagonists - therapeutic use
Adult
Aged
Aged, 80 and over
Alberta - epidemiology
Angioplasty, Balloon, Coronary
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Coronary Angiography
Coronary Artery Bypass
Female
Hospital Mortality
Humans
Incidence
Length of Stay
Male
Middle Aged
Myocardial Infarction - diagnosis - epidemiology - therapy
Patient Readmission
Predictive value of tests
Risk factors
Severity of Illness Index
Survival Analysis
Time Factors
Treatment Outcome
Abstract
The current survival trends in patients with acute myocardial infarction (AMI) are not known. A population-based study using administrative data to examine the short and long term survival of patients after AMI in Alberta between 1994 and 1999 was conducted.
AMI patients were identified from hospital discharge data. Temporal changes in the adjusted (age, sex, AMI anatomical location and comorbidities) fatality rate were analyzed in 19,928 AMI patients.
The age- and sex-adjusted incidence of hospitalization for AMI in Alberta significantly declined from 169.6 per 100,000 population in 1994 to 160.8 per 100,000 in 1999 (P=0.03). The risk-adjusted in-hospital case fatality rate from all causes was 11.4% (95% CI 10.6% to 12.3%) in 1994 versus 9.2% (8.4% to 10.1%) in 1999; the 30-day case fatality rate was 12.6% (11.7% to 13.6%) in 1994 versus 10.1% (9.1% to 11.0%) in 1999; and the one-year case fatality rate was 19.0% (17.8% to 20.1%) in 1994 versus 14.9% (13.8% to 16.0%) in 1999. The percentage of hospitalized AMI patients who underwent coronary angiography within one year after admission rose from 48.2% in 1994 to 52.4% in 1999; percutaneous transluminal coronary angioplasty increased from 25.5% to 35.0% and coronary artery bypass surgery increased from 9.7% to 12.6%. Prescriptions for pharmacological drugs at discharge increased from 1994 to 1999 among patients aged 65 and older: from 29.5% in 1994 to 41.0% in 1999 for beta-blockers, from 5.2% to 18.7% for lipid lowering agents and from 14.0% to 20.5% for angiotensin-converting enzyme inhibitors.
There was a modest improvement in patient survival after AMI between 1994 and 1999. The improvements may be associated with increasing use of revascularization and pharmacological therapy provided in the management of AMI.
PubMed ID
15010746 View in PubMed
Less detail

Acute myocardial infarction in Canada: improvement with time.

https://arctichealth.org/en/permalink/ahliterature197737
Source
CMAJ. 2000 Jul 11;163(1):41-2
Publication Type
Article
Date
Jul-11-2000
Author
A. Dodek
Author Affiliation
Cardiac Catheterization Laboratories, St. Paul's Hospital, Vancouver, BC.
Source
CMAJ. 2000 Jul 11;163(1):41-2
Date
Jul-11-2000
Language
English
Publication Type
Article
Keywords
Adrenergic beta-Antagonists - therapeutic use
Angioplasty, Balloon, Coronary
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Cardiovascular Agents - therapeutic use
Databases as Topic
Humans
Hypolipidemic Agents - therapeutic use
Myocardial Infarction - therapy
Outcome Assessment (Health Care)
Quebec
Survival Rate
Thrombolytic Therapy
Treatment Outcome
Notes
Cites: N Engl J Med. 1994 Oct 27;331(17):1130-57935638
Cites: N Engl J Med. 1999 Aug 26;341(9):625-3410460813
Cites: J Am Coll Cardiol. 1998 Aug;32(2):360-79708461
Cites: N Engl J Med. 1999 Nov 4;341(19):1413-910547403
Cites: J Am Coll Cardiol. 1999 Nov 1;34(5):1388-9410551683
Cites: CMAJ. 2000 Jul 11;163(1):31-610920727
Cites: N Engl J Med. 1993 Mar 18;328(11):779-848123063
Cites: Can J Cardiol. 1999 Oct;15(10):1095-10210523476
Cites: Can J Cardiol. 1995 Jun;11(6):477-867780868
Cites: N Engl J Med. 1996 Oct 3;335(14):1001-98801446
Cites: N Engl J Med. 1996 Oct 17;335(16):1198-2058815943
Cites: N Engl J Med. 1996 Dec 19;335(25):1888-968948565
Cites: Am J Cardiol. 1997 Jun 1;79(11):1441-69185630
Comment In: CMAJ. 2001 Feb 6;164(3):323-411232128
Comment In: CMAJ. 2001 Feb 6;164(3):323; author reply 32411232129
Comment On: CMAJ. 2000 Jul 11;163(1):31-610920727
PubMed ID
10920730 View in PubMed
Less detail

388 records – page 1 of 39.