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151 records – page 1 of 16.

Accuracy of the Alberta Stroke Program Early CT Score during the first 3 hours of middle cerebral artery stroke: comparison of noncontrast CT, CT angiography source images, and CT perfusion.

https://arctichealth.org/en/permalink/ahliterature158816
Source
AJNR Am J Neuroradiol. 2008 May;29(5):931-6
Publication Type
Article
Date
May-2008
Author
K. Lin
O. Rapalino
M. Law
J S Babb
K A Siller
B K Pramanik
Author Affiliation
Department of Radiology, New York University Medical Center, New York, NY, USA. kelinmd@gmail.com
Source
AJNR Am J Neuroradiol. 2008 May;29(5):931-6
Date
May-2008
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Alberta
Cerebral Angiography - methods
Contrast Media
Female
Humans
Infarction, Middle Cerebral Artery - radiography
Male
Middle Aged
Reproducibility of Results
Sensitivity and specificity
Severity of Illness Index
Tomography, X-Ray Computed - methods
Abstract
The Alberta Stroke Program Early CT Score (ASPECTS) is a reliable method of delineating the extent of middle cerebral artery (MCA) stroke. Our aim was to retrospectively compare the accuracy of ASPECTS on noncontrast CT, CT angiography (CTA) source images, and CT perfusion maps of cerebral blood volume (CBV) during the first 3 hours of middle cerebral artery (MCA) stroke.
First-time patients with MCA stroke who presented
PubMed ID
18272553 View in PubMed
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Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain-the WESTCOR study: study design.

https://arctichealth.org/en/permalink/ahliterature310408
Source
Scand Cardiovasc J. 2019 Oct; 53(5):280-285
Publication Type
Journal Article
Date
Oct-2019
Author
Hilde L Tjora
Ole-Thomas Steiro
Jørund Langørgen
Rune Bjørneklett
Ottar K Nygård
Renate Renstrøm
Øyvind Skadberg
Vernon V S Bonarjee
Bertil Lindahl
Paul Collinson
Torbjørn Omland
Kjell Vikenes
Kristin M Aakre
Author Affiliation
Emergency Care Clinic, Haukeland University Hospital , Bergen , Norway.
Source
Scand Cardiovasc J. 2019 Oct; 53(5):280-285
Date
Oct-2019
Language
English
Publication Type
Journal Article
Keywords
Acute Coronary Syndrome - blood - diagnosis - mortality
Algorithms
Angina, Unstable - blood - diagnosis - mortality
Biomarkers - blood
Computed Tomography Angiography
Coronary Angiography - methods
Cross-Sectional Studies
Humans
Multicenter Studies as Topic
Non-ST Elevated Myocardial Infarction - blood - diagnosis - mortality
Norway
Observational Studies as Topic
Predictive value of tests
Prognosis
Prospective Studies
Reproducibility of Results
Research Design
Troponin - blood
Abstract
Objectives. The main aim of the Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain (WESTCOR-study) (Clinical Trials number NCT02620202) is to improve diagnostic pathways for patients presenting to the Emergency department (ED) with acute chest pain. Design. The WESTCOR-study is a two center, cross-sectional and prospective observational study recruiting unselected patients presenting to the ED with suspected non-ST elevation acute coronary syndrome (NSTE-ACS). Patient inclusion started September 2015 and we plan to include 2250 patients, finishing in 2019. The final diagnosis will be adjudicated by two independent cardiologists based on all available information including serial high sensitivity cardiac troponin measurements, coronary angiography, coronary CT angiography and echocardiography. The study includes one derivation cohort (N?=?985) that will be used to develop rule out/rule in algorithms for NSTEMI and NSTE-ACS (if possible) using novel troponin assays, and to validate established NSTEMI algorithms, with and without clinical scoring systems. The study further includes one subcohort (n?=?500) where all patients are examined with coronary CT angiography independent of biomarker status, aiming to assess the associations between biomarkers and the extent and severity of coronary atherosclerosis. Finally, an external validation cohort (N?=?750) will be included at Stavanger University Hospital. Prospective studies will be based on the merged cohorts. Conclusion. The WESTCOR study will provide new diagnostic algorithms for early inclusion and exclusion of NSTE-ACS and insights in the associations between cardiovascular biomarkers, CT-angiographic findings and short and long-term clinical outcomes.
PubMed ID
31216908 View in PubMed
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The Alberta Stroke Program Early CT Score in clinical practice: what have we learned?

https://arctichealth.org/en/permalink/ahliterature148474
Source
Int J Stroke. 2009 Oct;4(5):354-64
Publication Type
Article
Date
Oct-2009
Author
V. Puetz
I. Dzialowski
M D Hill
A M Demchuk
Author Affiliation
Department of Neurology, Dresden University Stroke Centre, University of Technology Dresden, Dresden, Germany.
Source
Int J Stroke. 2009 Oct;4(5):354-64
Date
Oct-2009
Language
English
Publication Type
Article
Keywords
Alberta
Brain Ischemia - drug therapy - radiography
Cerebral Angiography - methods
Humans
Predictive value of tests
Prognosis
Reproducibility of Results
Stroke - drug therapy - physiopathology - radiography
Thrombolytic Therapy - adverse effects
Time Factors
Tomography, X-Ray Computed - methods
Abstract
The introduction of brain imaging with computed tomography revolutionised the treatment of patients with acute ischaemic stroke. With the visual differentiation of haemorrhagic stroke from ischaemic stroke, thrombolytic therapy became feasible. The Alberta Stroke Program Early CT Score was devised to quantify the extent of early ischaemic changes in the middle cerebral artery territory on noncontrast computed tomography. With its systematic approach, the score is simple and reliable. However, the assessment of early ischaemic changes and Alberta Stroke Program Early CT scoring require training. The Alberta Stroke Program Early CT Score is a strong predictor of functional outcome. Furthermore, the effectiveness of intraarterial thrombolysis in patients with middle cerebral artery occlusion shows effect modification by the Alberta Stroke Program Early CT Score. This review summarises the Alberta Stroke Program Early CT Score methodology. We illustrate current knowledge regarding Alberta Stroke Program Early CT Score applied to clinical trials and comment on how Alberta Stroke Program Early CT Score may facilitate clinical treatment decision making and future trial design. Moreover, we introduce a modification of the Alberta Stroke Program Early CT Score methodology that disregards isolated cortical swelling, i.e. focal brain swelling without associated parenchymal hypoattenuation, as early ischaemic changes in the Alberta Stroke Program Early CT Score system.
PubMed ID
19765124 View in PubMed
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Angiography and phlebography in a hemodialysis population: A retrospective analysis of interventional results.

https://arctichealth.org/en/permalink/ahliterature309359
Source
Int J Artif Organs. 2019 Dec; 42(12):675-683
Publication Type
Journal Article
Date
Dec-2019
Author
Ursula Hadimeri
Anna Wärme
Salmir Nasic
Sven-Göran Fransson
Ann Wigelius
Bernd Stegmayr
Author Affiliation
Department of Medical and Health Sciences, Linkoping University, Linkoping, Sweden.
Source
Int J Artif Organs. 2019 Dec; 42(12):675-683
Date
Dec-2019
Language
English
Publication Type
Journal Article
Keywords
Aged
Angiography - methods - statistics & numerical data
Angioplasty - adverse effects - methods
Arteriovenous Shunt, Surgical - adverse effects
Female
Graft Occlusion, Vascular - etiology - prevention & control - surgery
Humans
Male
Middle Aged
Phlebography - methods - statistics & numerical data
Renal Dialysis - adverse effects - methods
Retrospective Studies
Risk assessment
Risk factors
Sweden - epidemiology
Treatment Outcome
Vascular Patency
Abstract
To clarify the reasons and beneficial effects and duration of arteriovenous fistula patency after radiological interventions in arteriovenous fistula. The patients investigated were referred due to arteriovenous fistula access flow problems.
In 174 patients, 522 radiological investigations and endovascular treatments such as percutaneous transluminal angioplasty were analyzed, retrospectively. All investigations were performed due to clinical suspicion of impaired arteriovenous fistula function.
Arterial stenosis was significantly more frequent among patients with diabetic nephropathy (p?
PubMed ID
31303134 View in PubMed
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Aortic root, not valve, calcification correlates with coronary artery calcification in patients with severe aortic stenosis: A two-center study.

https://arctichealth.org/en/permalink/ahliterature276151
Source
Atherosclerosis. 2015 Dec;243(2):631-7
Publication Type
Article
Date
Dec-2015
Author
Michael Henein
Peter Hällgren
Anders Holmgren
Karen Sörensen
Pranvera Ibrahimi
Klaus Fuglsang Kofoed
Linnea Hornbech Larsen
Christian Hassager
Source
Atherosclerosis. 2015 Dec;243(2):631-7
Date
Dec-2015
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Aorta - pathology
Aortic Diseases - complications - radiography
Aortic Valve - abnormalities - pathology - radiography
Aortic Valve Stenosis - complications - radiography
Aortography - methods
Calcinosis - complications - radiography
Coronary Angiography - methods
Coronary Artery Disease - complications - radiography
Coronary Stenosis - complications - radiography
Coronary Vessels - radiography
Denmark
Female
Heart Valve Diseases - complications - radiography
Humans
Male
Middle Aged
Multidetector Computed Tomography
Predictive value of tests
Prognosis
Severity of Illness Index
Sweden
Vascular Calcification - complications - radiography
Abstract
The underlying pathology in aortic stenosis (AS) and coronary artery stenosis (CAS) is similar including atherosclerosis and calcification. We hypothesize that coronary artery calcification (CAC) is likely to correlate with aortic root calcification (ARC) rather than with aortic valve calcification (AVC), due to tissue similarity between the two types of vessel rather than with the valve leaflet tissue.
We studied 212 consecutive patients (age 72.5 ± 7.9 years, 91 females) with AS requiring aortic valve replacement (AVR) in two Heart Centers, who underwent multidetector cardiac CT preoperatively. CAC, AVC and ARC were quantified using Agatston scoring. Correlations were tested by Spearman's test and Mann-Whitney U-test was used for comparing different subgroups; bicuspid (BAV) vs tricuspid (TAV) aortic valve.
CAC was present in 92%, AVC in 100% and ARC in 82% of patients. CAC correlated with ARC (rho = 0.51, p 50%), but these were not different in the pattern of calcification from those without CAS. CAC was consistently higher in patients with risk factors for atherosclerosis compared to those without.
The observed relationship between coronary and aortic root calcification suggests a diffuse arterial disease. The lack of relationship between coronary and aortic valve calcification suggests a different pathology.
PubMed ID
26551591 View in PubMed
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Association between high-sensitive troponin I and coronary artery calcification in a Danish general population.

https://arctichealth.org/en/permalink/ahliterature277319
Source
Atherosclerosis. 2016 Feb;245:88-93
Publication Type
Article
Date
Feb-2016
Author
Fredrik Olson
Jonathan Engborg
Mette H Grønhøj
Niels P Sand
Jess Lambrechtsen
Flemming H Steffensen
Mads Nybo
Oke Gerke
Hans Mickley
Axel C P Diederichsen
Source
Atherosclerosis. 2016 Feb;245:88-93
Date
Feb-2016
Language
English
Publication Type
Article
Keywords
Calcinosis - blood - diagnosis - epidemiology
Coronary Angiography - methods
Coronary Artery Disease - blood - diagnosis - epidemiology
Coronary Vessels - radiography
Denmark - epidemiology
Female
Humans
Incidence
Male
Middle Aged
Prognosis
ROC Curve
Risk Assessment - methods
Risk factors
Survival Rate - trends
Tomography, X-Ray Computed
Troponin I - blood
Abstract
High-sensitive troponin I (hs-TnI) is an individual predictor of future cardiovascular disease (CVD). However, the relationship between hs-TnI and coronary artery calcification (CAC) as determined by computed tomography (CT) has not previously been investigated in a general population.
1173 randomized, middle-aged subjects without known CVD underwent a non-contrast cardiac-CT scan for CAC determination. Hs-TnI was detected using ARCHITECT STAT High Sensitive Troponin-I immunoassay. Total 10-year cardiovascular mortality risk was estimated using HeartScore. The relationship between hs-TnI and CAC was assessed using logistic regression analyses and receiver operating characteristic curves (ROC).
Concentrations of hs-TnI above the limit of detection were measured in 89.3% of all subjects. Presence of CAC (Agatston score >0) was detected in 29% in the lowest hs-TnI quartile compared with 55% in the highest, with a stepwise increase over the quartiles. In fully adjusted regression models with dichotomous CAC outcomes, hs-TnI was able to predict presence of CAC (OR: 1.25, 95% CI: 1.03-1.51, p = 0.025) and an Agatston score >100 (OR: 1.36, 95% CI: 1.08-1.71, p = 0.009). Subjects in the fourth hs-TnI quartile had an increased risk for presence of CAC (OR: 1.56, 95% CI: 1.06-2.26, p = 0.024) and for an Agatston score >100 (OR: 1.82, 95% CI: 1.04-3.18, p = 0.035), when compared with the first quartile. Addition of hs-TnI to HeartScore improved the ROCAUC from 0.671 to 0.695 (p
PubMed ID
26714045 View in PubMed
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Association of ischemic heart disease to global and regional longitudinal strain in asymptomatic aortic stenosis.

https://arctichealth.org/en/permalink/ahliterature268800
Source
Int J Cardiovasc Imaging. 2015 Mar;31(3):485-95
Publication Type
Article
Date
Mar-2015
Author
Helle Gervig Carstensen
Linnea Hornbech Larsen
Christian Hassager
Klaus Fuglsang Kofoed
Jan Skov Jensen
Rasmus Mogelvang
Source
Int J Cardiovasc Imaging. 2015 Mar;31(3):485-95
Date
Mar-2015
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Aortic Valve Stenosis - diagnosis - epidemiology - physiopathology
Asymptomatic Diseases
Coronary Angiography - methods
Coronary Artery Disease - diagnosis - epidemiology - physiopathology
Coronary Stenosis - diagnosis - epidemiology - physiopathology
Denmark - epidemiology
Echocardiography, Doppler
Female
Humans
Male
Middle Aged
Multidetector Computed Tomography
Multimodal Imaging
Myocardial Contraction
Predictive value of tests
Prevalence
Prospective Studies
Risk factors
Severity of Illness Index
Stress, mechanical
Ventricular Dysfunction, Left - diagnosis - epidemiology - physiopathology
Ventricular Function, Left
Abstract
Longitudinal deformation has been shown to deteriorate with progressive aortic stenosis as well as ischemic heart disease. Despite that both conditions share risk factors and are often coexisting, studies have not assessed the influence on longitudinal deformation for both conditions simultaneously. Thus the purpose of this study was to evaluate the association between subclinical ischemic heart disease and global and regional longitudinal strain in asymptomatic patients with significant aortic stenosis. Prevalent patients with a diagnosis of aortic stenosis at six hospitals in the Greater Copenhagen area were screened for inclusion. A total of 104 asymptomatic patients with moderate-severe aortic stenosis (aortic valve area =1.5 cm(2)) fulfilled study criteria and underwent advanced echocardiographic analysis and coronary angiography by multi-detector computed tomography. Angiography revealed coronary stenosis >50% in 31% (n = 32). All regional longitudinal strain measures (apical, mid and basal longitudinal strain) were significant predictors of significant coronary stenosis (>70% stenosis), but only apical and mid longitudinal strain were significant predictors in multivariable analyses independent of aortic valve area, stroke volume index, pro-BNP, valvulo-arterial impedance, body mass index and heart rate. In linear regression models with both aortic valve area and significant coronary stenosis, apical (p
PubMed ID
25404082 View in PubMed
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Association of lumbar arterial stenosis with low back symptoms: a cross-sectional study using two-dimensional time-of-flight magnetic resonance angiography.

https://arctichealth.org/en/permalink/ahliterature90701
Source
Acta Radiol. 2009 Jan;50(1):48-54
Publication Type
Article
Date
Jan-2009
Author
Korkiakoski A.
Niinimäki J.
Karppinen J.
Korpelainen R.
Haapea M.
Natri A.
Tervonen O.
Author Affiliation
Institute of Clinical Sciences, Department of Physical and Rehabilitation Medicine, University of Oulu, Oulu, Finland. atkorkia@paju.oulu.fi
Source
Acta Radiol. 2009 Jan;50(1):48-54
Date
Jan-2009
Language
English
Publication Type
Article
Keywords
Adult
Arterial Occlusive Diseases - complications - diagnosis - physiopathology
Cross-Sectional Studies
Finland
Humans
Image Interpretation, Computer-Assisted
Logistic Models
Low Back Pain - etiology - physiopathology
Lumbosacral Region - blood supply
Magnetic Resonance Angiography - methods
Male
Middle Aged
Pain Measurement
Abstract
BACKGROUND: Recent studies indicate that diminished blood flow may cause low back symptoms and intervertebral disc degeneration. PURPOSE: To explore the association between lumbar arterial stenosis as detected by two-dimensional time-of-flight magnetic resonance angiography (2D TOF-MRA) and lumbar pain symptoms in an occupational cohort of middle-aged Finnish males. MATERIAL AND METHODS: 228 male subjects aged 36 to 55 years (mean 47 years) were imaged with 2D TOF-MRA. Additionally, 20 randomly selected subjects were scanned with contrast-enhanced MRA (ceMRA). In each subject, the first (L1) to fourth (L4) segmental lumbar arteries were evaluated for lumbar artery stenosis using a dichotomic scale. One subject was excluded because of poor image quality, reducing the study population to 227 subjects. Logistic regression analysis was used to evaluate the association between arterial stenosis in 2D TOF-MRA and low back pain and sciatica symptoms (intensity, duration, frequency). RESULTS: Comparing 2D TOF-MRA and ceMRA images, the kappa value (95% confidence interval) was 0.52 (0.31-0.73). The intraobserver reliability kappa value for 2D TOF-MRA was 0.85 (0.77-0.92), and interobserver kappa was 0.57 (0.49-0.65). The sensitivity of 2D TOF-MRA in detecting stenosis was 0.58, the accuracy 0.89, and the specificity 0.94. In 97 (43%) subjects all arteries were normal, whereas 130 (57%) had at least one stenosed artery. The left L4 artery was most often affected. The degree of arterial stenosis was associated with intensity of low back and sciatic pain, and sciatica pain duration during the past 3 months. CONCLUSION: 2D TOF-MRA is an acceptable imaging method for arterial stenosis compared to ceMRA. Arterial stenosis was associated with subjective pain symptoms, indicating a role of decreased nutrition in spinal disorders.
PubMed ID
19096951 View in PubMed
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Atherosclerosis imaging and the Canadian Atherosclerosis Imaging Network.

https://arctichealth.org/en/permalink/ahliterature118012
Source
Can J Cardiol. 2013 Mar;29(3):297-303
Publication Type
Article
Date
Mar-2013
Author
Jean-Claude Tardif
J David Spence
Therese M Heinonen
Alan Moody
Josephine Pressacco
Richard Frayne
Philippe L'allier
Benjamin J W Chow
Matthias Friedrich
Sandra E Black
Aaron Fenster
Brian Rutt
Rob Beanlands
Author Affiliation
Montreal Heart Institute, Université de Montréal, Montréal, Québec, Canada. jean-claude.tardif@icm-mhi.org
Source
Can J Cardiol. 2013 Mar;29(3):297-303
Date
Mar-2013
Language
English
Publication Type
Article
Keywords
Algorithms
Angiography - methods
Atherosclerosis - diagnosis - prevention & control - therapy
Canada
Carotid Arteries - pathology - radiography - radionuclide imaging - ultrasonography
Contrast Media - diagnostic use
Diagnostic Imaging - methods
Echocardiography, Three-Dimensional - methods
Evidence-Based Medicine
Humans
Magnetic Resonance Imaging - methods
Multimodal Imaging - methods
Positron-Emission Tomography
Regression Analysis
Research Design
Risk assessment
Risk factors
Tomography, X-Ray Computed - methods
Abstract
Atherosclerosis exacts a large toll on society in the form of cardiovascular morbidity, mortality, and resource use and is exacerbated by the epidemics of obesity and diabetes. Consequently, there is a critical need for more-effective methods of diagnosis, treatment, and prevention of the complications of atherosclerosis. Careful and well-conducted large population studies are needed in order to truly understand the natural history of the disease, its imaging biomarkers, and their links to patient outcomes. The Canadian Atherosclerosis Imaging Network (CAIN) is a unique research network funded by the Canadian Institutes of Health Research and the Canada Foundation for Innovation and designed to address these needs and to enable large population-based imaging studies. The central objective of CAIN is to move innovations in imaging toward their broad application in clinical research and clinical practice for the improved evaluation of cardiac and neurologic vascular disease. CAIN is established as an international resource for studying the natural history, progression, and regression of atherosclerosis, as well as novel therapeutic interventions aimed at atherosclerosis. The network represents Canada's leading atherosclerosis imaging experts, embodying both basic imaging science and clinical imaging research. The network is improving methods of detection and treatment of atherosclerosis and, through a better understanding of the underlying disease itself, improving strategies for disease prevention. The benefits are expected to appear in the next 2 to 3 years. CAIN will drive innovation in imaging technology within the field of cardiology and neurology and improve health outcomes in Canada and worldwide.
PubMed ID
23245557 View in PubMed
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Bioresorbable Vascular Scaffolds in a Real-World Patient Population-Results From a Mid-Term Angiographic Follow-Up.

https://arctichealth.org/en/permalink/ahliterature281934
Source
J Interv Cardiol. 2016 Aug;29(4):341-7
Publication Type
Article
Date
Aug-2016
Author
Mohammed Saad
Amr Abdin
Holger Thiele
Steffen Desch
Pranvera Ibrahimi
Gerhard Wikstroem
Martin Hoeher
Michael Henein
Source
J Interv Cardiol. 2016 Aug;29(4):341-7
Date
Aug-2016
Language
English
Publication Type
Article
Keywords
Absorbable Implants - adverse effects - statistics & numerical data
Aged
Coronary Angiography - methods
Female
Follow-Up Studies
Humans
Incidence
Male
Middle Aged
Outcome and Process Assessment (Health Care)
Percutaneous Coronary Intervention - adverse effects - instrumentation - methods
Postoperative Complications - diagnosis - epidemiology
Sweden - epidemiology
Treatment Outcome
Abstract
We aimed to investigate the safety and efficacy of bioresorbable vascular scaffolds (BVS) in daily use in a real-world patient population.
Between March 2013 and September 2014, 224 patients (233 lesions) were treated with BVS at a tertiary care center. Patients underwent follow-up coronary angiography 3-6 months after implantation. Clinical presentations were stable angina in 101 patients (45.1%), unstable angina in 47 (21.0%), NSTEMI in 38 (17.0%), and STEMI in 38 (17.0%) patients. Twenty-two patients (27 lesions) had chronic total occlusion (CTO). Procedural success was achieved in all patients. Two patients died in the follow-up period due to BVS thrombosis (0.9%). In-hospital death occurred in further 3 patients (1.3%) due to other causes not related to the BVS implantation. Total BVS thrombosis was 3.1% (7 patients) and there was only 1 case of relevant restenosis on angiographic follow-up. The overall incidence of major adverse cardiac events was 11 (4.9%).
Mid-term follow-up after implantation of BVS suggests a satisfactory safety profile and low restenosis rate in routine daily practice involving a large range of complex lesions.
PubMed ID
27329969 View in PubMed
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151 records – page 1 of 16.