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Anencephalus and drinking water composition.

https://arctichealth.org/en/permalink/ahliterature249965
Source
Am J Epidemiol. 1977 May;105(5):460-8
Publication Type
Article
Date
May-1977
Author
J M Elwood
Source
Am J Epidemiol. 1977 May;105(5):460-8
Date
May-1977
Language
English
Publication Type
Article
Keywords
Anencephaly - epidemiology - etiology - mortality
Calcium - analysis
Canada
Congenital Abnormalities - mortality
Drinking
Female
Fetal Death - epidemiology
Fresh Water - analysis
Humans
Hydrocephalus - mortality
Lithium - analysis
Magnesium - analysis
Pregnancy
Spinal Dysraphism - mortality
Water - analysis
Water Softening
Water supply
Abstract
The mortality rate (stillbirths and infant deaths) from anencephalus from 1950-1969 in 36 cities of over 50,000 population in Canada showed a negative association (r = -.39) with the concentration of magnesium in water sampled at domestic taps. The mortality rates showed negative associations with mean income and longitude, and a multiple regression model using the three factors showed significant effects of each and accounted for 69% of the intercity variation in rates. There were no significant associations seen with water calcium concentration or total hardness. Income, magnesium and longitude were also negatively associated with mortality rates from spina bifida, hydrocephalus, other congenital abnormalities, and total stillbirth and infant death rates, but the association with magnesium was significant only for total stillbirths. The negative association of anencephalus mortality and magnesium levels was also seen in a sample of 14 smaller towns in Ontario.
PubMed ID
324271 View in PubMed
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Anencephaly and spina bifida in the Province of Quebec.

https://arctichealth.org/en/permalink/ahliterature110114
Source
Can Med Assoc J. 1969 Apr 26;100(16):748-55
Publication Type
Article
Date
Apr-26-1969
Author
I. Horowitz
A D McDonald
Source
Can Med Assoc J. 1969 Apr 26;100(16):748-55
Date
Apr-26-1969
Language
English
Publication Type
Article
Keywords
Anencephaly - epidemiology - etiology - genetics
Birth Order
Diseases in Twins - epidemiology
Ethnic Groups
Female
Fetal Death - etiology
Geography
Humans
Infant mortality
Jews
Male
Maternal Age
Parity
Pregnancy
Quebec
Rural Population
Seasons
Socioeconomic Factors
Spinal Dysraphism - epidemiology - etiology - genetics
Urban Population
Notes
Cites: Br J Prev Soc Med. 1964 Jul;18:152-614198229
Cites: Br J Soc Med. 1950 Jan;4(1):26-5015426747
Cites: J Am Med Assoc. 1959 Oct 10;171:638-4113845103
Cites: Lancet. 1966 Oct 8;2(7467):791-34162336
Cites: Lancet. 1967 Feb 11;1(7485):306-84163511
Cites: Br J Prev Soc Med. 1967 Apr;21(2):66-774382329
Cites: J Ment Defic Res. 1967 Mar;11(1):54-74226780
Cites: N Engl J Med. 1967 Nov 23;277(21):1119-234861562
Cites: Lancet. 1951 Jan 27;1(6648):192-614795817
Cites: Br J Prev Soc Med. 1957 Oct;11(4):174-8013536294
Cites: Lancet. 1958 Jun 21;1(7034):1304-613550991
Cites: Br J Prev Soc Med. 1960 Oct;14:167-7213723558
Cites: Lancet. 1959 Nov 28;2(7109):935-813810875
Cites: Br J Prev Soc Med. 1962 Jul;16:153-813898971
Cites: Br J Prev Soc Med. 1962 Jul;16:159-6213903150
Cites: Br J Prev Soc Med. 1963 Apr;17:70-8013928952
Cites: Am J Dis Child. 1963 Dec;106:536-4414063702
Cites: Nature. 1963 Nov 2;200:480-114076742
Cites: Br J Prev Soc Med. 1964 Jan;18:1-714113806
Cites: Dev Med Child Neurol. 1964 Jun;6:231-4014155181
Cites: Arch Dis Child. 1964 Feb;39:41-5714160086
PubMed ID
4888983 View in PubMed
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Fallout from the Chernobyl nuclear disaster and congenital malformations in Europe.

https://arctichealth.org/en/permalink/ahliterature58526
Source
Arch Environ Health. 2001 Nov-Dec;56(6):478-84
Publication Type
Article
Author
W. Hoffmann
Author Affiliation
Bremen Institute for Prevention Research, Social Medicine and Epidemiology (BIPSE) Bremen, Germany. Hoffmann@uni-bremen.de
Source
Arch Environ Health. 2001 Nov-Dec;56(6):478-84
Language
English
Publication Type
Article
Keywords
Abnormalities, Radiation-Induced - epidemiology
Abortion, Spontaneous - epidemiology - etiology
Accidents, Radiation
Anencephaly - epidemiology - etiology
Animals
Byelarus - epidemiology
Chromosome Aberrations
Comparative Study
Confidence Intervals
Croatia - epidemiology
Down Syndrome - epidemiology - etiology
Europe - epidemiology
Female
Finland - epidemiology
Germany - epidemiology
Humans
Infant, Newborn
Male
Neural Tube Defects - epidemiology - etiology
Power Plants
Pregnancy
Prevalence
Prospective Studies
Public Health
Radiation Protection
Radioactive fallout
Risk
Turkey - epidemiology
Ukraine
Abstract
Investigators estimate that the population exposure that resulted from the Chernobyl fallout is in the range of natural background radiation for most European countries. Given current radiobiologic knowledge, health effects-if any-would not be measurable with epidemiologic tools. In several independent reports, however, researchers have described isolated peaks in the prevalence of congenital malformations in the cohort conceived immediately after onset of the fallout. The consistency of the time pattern and the specific types of malformation raise concern about their significance. In this study, the author summarizes findings from Turkey, Belarus, Croatia, Finland, Germany, and other countries, and implications for radiation protection and public health issues are discussed.
PubMed ID
11958546 View in PubMed
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International variation in the prevalence at birth of anencephalus in relation to maternal factors.

https://arctichealth.org/en/permalink/ahliterature243152
Source
Int J Epidemiol. 1982 Jun;11(2):132-7
Publication Type
Article
Date
Jun-1982
Author
J M Elwood
J H Elwood
Source
Int J Epidemiol. 1982 Jun;11(2):132-7
Date
Jun-1982
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Anencephaly - epidemiology - etiology
Canada
Cross-Sectional Studies
Epidemiologic Methods
Female
Humans
Infant, Newborn
Male
Maternal Age
Northern Ireland
Parity
Pedigree
Pregnancy
Risk
Abstract
Information from series of cases of anencephalus and corresponding random samples of all livebirths showed that the prevalence rate at birth per 1000 livebirths for anencephalus was 4.02 in Belfast (from 1957 to 1969), compared to 1.36 in mothers of Scots-Irish origin resident in 14 selected Canadian cities (from 1950 to 1969). For each of these two populations, anencephalus was associated with the number of previous livebirths, stillbirths, and child deaths. However, these maternal factors did not account for any appreciable portion of the difference in prevalence rates between the two populations, showing that a different set of factors must cause the international difference in rates.
PubMed ID
6980196 View in PubMed
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Neural tube defects in Quebec. A search for evidence of 'clustering' in time and place.

https://arctichealth.org/en/permalink/ahliterature255675
Source
Br J Prev Soc Med. 1972 Feb;26(1):10-4
Publication Type
Article
Date
Feb-1972
Author
J. Siemiatycki
A D McDonald
Source
Br J Prev Soc Med. 1972 Feb;26(1):10-4
Date
Feb-1972
Language
English
Publication Type
Article
Keywords
Anencephaly - epidemiology - etiology
Epidemiologic Methods
Humans
Quebec
Spinal Dysraphism - epidemiology - etiology
Notes
Cites: Cancer Res. 1967 Feb;27(2):209-206018555
Cites: Br J Prev Soc Med. 1966 Apr;20(2):67-756006381
Cites: Am J Epidemiol. 1969 Feb;89(2):154-604885535
Cites: Can Med Assoc J. 1969 Apr 26;100(16):748-554888983
Cites: Cancer Res. 1969 Nov;29(11):1995-20015358216
Cites: Am J Epidemiol. 1971 Jul;94(1):26-304933669
Cites: Lancet. 1951 Jan 27;1(6648):192-614795817
Cites: Br J Prev Soc Med. 1962 Jul;16:153-813898971
Cites: Br J Prev Soc Med. 1962 Jul;16:159-6213903150
Cites: Br J Prev Soc Med. 1964 Jan;18:1-714113806
Cites: Br J Prev Soc Med. 1964 Jan;18:17-2414117764
Cites: Am J Hum Genet. 1964 Sep;16:336-5014207549
Cites: Br Med J. 1960 Jan 30;1(5169):309-1514433486
PubMed ID
4552624 View in PubMed
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Sex differences in prevalence of congenital neural defects after periconceptional famine exposure.

https://arctichealth.org/en/permalink/ahliterature59143
Source
Epidemiology. 1997 Jan;8(1):55-8
Publication Type
Article
Date
Jan-1997
Author
A S Brown
E S Susser
Author Affiliation
Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, USA.
Source
Epidemiology. 1997 Jan;8(1):55-8
Date
Jan-1997
Language
English
Publication Type
Article
Keywords
Anencephaly - epidemiology - etiology - mortality
Cohort Studies
Comparative Study
Confidence Intervals
Denmark - epidemiology
Female
Humans
Incidence
Infant Nutrition Disorders - complications
Infant, Newborn
Male
Neural Tube Defects - epidemiology - etiology - mortality
Research Support, U.S. Gov't, P.H.S.
Risk factors
Sex Distribution
Spinal Dysraphism - epidemiology - etiology - mortality
War
Abstract
The purpose of this investigation was to examine the sex distribution of deaths from spina bifida in birth cohorts exposed and unexposed to severe periconceptional famine. For this purpose, we compared the risk of deaths from spina bifida between birth cohorts exposed and unexposed to the Dutch Hunger Winter of 1944-1946. In males, the relative risk of death from spina bifida was 2.62 [95% confidence interval (CI) = 1.14-6.01]. In females, the relative risk for spina bifida was 0.59 (95% CI = 0.14-2.37). The sex ratio (male:female) for deaths from spina bifida in the exposed birth cohort was 2.74; a female predominance was not seen in any other birth cohort. Deaths from anencephaly and other central nervous system disorders did not exhibit this male predominance in the exposed birth cohort. These findings indicate that severe periconceptional nutrient deficiency may have a greater effect on the occurrence of spina bifida in males vs females. Other potential explanations include sex-specific effects of prenatal famine on prenatal or postnatal survival rates of cases.
PubMed ID
9116096 View in PubMed
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Twinning and anencephalus occurrence in relation to fetus-fetus interaction.

https://arctichealth.org/en/permalink/ahliterature251288
Source
Br J Prev Soc Med. 1976 Mar;30(1):29-31
Publication Type
Article
Date
Mar-1976
Author
J M Elwood
Source
Br J Prev Soc Med. 1976 Mar;30(1):29-31
Date
Mar-1976
Language
English
Publication Type
Article
Keywords
Anencephaly - epidemiology - etiology
Canada
Diseases in Twins
Epidemiologic Methods
Female
Humans
Infant, Newborn
Male
Pregnancy
Sex Factors
Twins
Twins, Dizygotic
Abstract
The hypothesis proposed by Knox (1970) that an anencephalic fetus arises from a fetus-fetus interaction between two dizygous twins predicts that the twinning rate, the population incidence of anencephalus, and the female proportion of anencephalics in a population should be positively interrelated. These associations were tested using Canadian data during a long period of time and over a large geographical area. The results did not support the hypothesis.
Notes
Cites: Am J Hum Genet. 1962 Dec;14:410-2514028923
Cites: Br J Prev Soc Med. 1973 Nov;27(4):236-414760507
Cites: Dev Med Child Neurol. 1970 Apr;12(2):167-774911461
PubMed ID
949570 View in PubMed
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10 records – page 1 of 1.