The purpose of this study was analysis of forensic medical aspects of macro- and trace element composition of hairs of the head in the residents of Mexico, Ecuador, Bolivia, Brazil, Columbia and changes in this characteristic during adaptation to conditions of Central Russia. One of our tasks was to define expert criteria for differentiation between the hairs belonging to residents of these countries and Russia. A total of 136 hairs were examined by spectral approximated quantitative analysis using DFS-13 spectrographer. The detected regularity consisted in the following: adaptation of residents of Latin America to conditions of Central Russia was associated with disappearance of some elements and appearance of other ones characteristic of residents of Central Russia (Byelorussians, Russians, Ukrainians).
The word deals with the results obtained in the study of the reactogenicity and immunological activity of concentrated and inactivated tissue-culture tick-borne encephalitis vaccine, manufactured by the Chumakov Institute of Poliomyelitis and Viral Encephalitides, in the immunization of children and adolescents. The vaccine proved to be moderately reactogenic and exhibited pronounced immunological activity. In 91.5% of the immunized children the fourfold increase of the antibody level was observed. On the basis of the data obtained in this study the tick-borne encephalitis vaccine was recommended for use in medical practice for the prophylaxis of tick-borne encephalitis among children and adolescents.
Aim of the study was to analyze causes of pulmonary artery thromboembolism (PATE) hypodiagnostics at prehospital stage. We compared clinical and electrocardiographic picture of acute period of the disease in groups of patients with diagnosed (n=61) and undiagnosed (n=22) PATE at prehospital stage. We also assessed retrospectively probability of PATE according to Revised Geneva Score. In 49 cases we analyzed dynamics of the acute period of PATE. The analysis showed that in more than 50% of cases hypodiagnostics of PATE was caused by similarity of observed clinical and electrocardiographical picture and that of acute coronary syndrome. There were no differences between groups in Revised Geneva Score.
The extensive use of adsorbed diphtheria-tetanus toxoid with reduced antigen content was found to be ineffective in the prophylaxis of diphtheria: 86.3% of diphtheria patients among those who had been immunized with this preparation fell only a year after the first booster immunization, and the proportion of those who proved to be unprotected against diphtheria on years 3, 4 and 5 after immunization reached, respectively, 21.0%, 35.5% and 49.4%. The number of children immunized with this preparation at common preschool institutions may reach 50% and more, and with an increase in the coverage of children with immunization from 10% to 50% the proportion of unprotected children may rise from 7.4% to 17.8%. The proportion of preschool institutions, insufficiently protected from diphtheria and, as a consequence, running a considerable risk of becoming (in case of the penetration of this infection) the foci of diphtheria, was found to reach 32.9%.
The experiments on 176 Wistar rats were performed for the first time to clarify mechanisms underlying anti-inflammatory action of the Deshembinskoe Lake mud in experimental arthritis. The new data obtained gave evidence supporting application of Deshembinskoe Lake mud in inflammatory diseases of the joints.
As shown by investigations of alkaline phosphatase, plasma levels of calcium, non-organic phosphorus, coefficient Ca/P in 58 patients with osteoarthrosis deformans before and after radon baths, mud applications or their combination, the highest biochemical effect was achieved in a group of patients on mud therapy.
The coverage of children having different pathology with prophylactic immunization is rather high and reaches, on the average, 82.3 +/- 0.7%. The immunization of children belonging to risk groups according to individual schedules and in combination with different measures aimed at the prevention of postvaccinal complications may be successfully carried out in pediatric practice under the conditions of a common polyclinic. After the vaccinal prophylaxis of such groups of children no postvaccinal complications and reactions to the administered immunobiological preparations have been observed.
The aim of the study is to evaluate the efficiency of "Colgate" tooth-paste on prophylaxis of caries and paradontic diseases. Carrying out of school program gave positive changes of the indices of the mouth cavity hygiene and inflammation of the gum mucous membrane. "Colgate" tooth-paste is effective in mouth cavity hygiene. It has medical-prophylactic properties.
A total of 142 children aged 2-15 years with different nephropathies, among them 94 children with glomerulonephritis (GN), 26 children with pyelonephritis and 22 children with oxalate nephropathy, were examined. The diagnosis was histologically confirmed in 36 children. Mesangial proliferative GN was detected in 22 patients and membrane proliferative GN, in 14 children. The presence of the markers of HBV infection (HBsAg, anti-HBs and anti-HBc total immunoglobulins, anti-HBc IgM) was detected in the sera of all patients by the enzyme immunoassay. As the result of this examination, essential changes in the distribution of different markers of HBV infection in children with nephropathies were detected. The combination of HBsAg with anti-HBc IgM proved to be the most characteristic feature of patients with the nephrotic syndrome; this was indicative of active HBV infection, and in patients with the mixed form of GN this combination occurred twice as frequently. The established correlation between the activity of HBV infection and the severity of the course of GN made it possible to suggest the participation of HBV in the pathogenesis of GN. This suggestion was indirectly confirmed by a higher detection rate of HBsAg and anti-HBc IgM in patients with the membrane proliferative form of GN.