Skip header and navigation

Refine By

303 records – page 1 of 31.

16th International Hypoxia Symposium at Chateau Lake Louise, March 10-14, 2009, Alberta, Canada.

https://arctichealth.org/en/permalink/ahliterature148383
Source
High Alt Med Biol. 2009;10(3):297-300
Publication Type
Conference/Meeting Material
Date
2009
Author
Erik R Swenson
Author Affiliation
eswenson@u.washington.edu
Source
High Alt Med Biol. 2009;10(3):297-300
Date
2009
Language
English
Publication Type
Conference/Meeting Material
Keywords
Alberta
Altitude Sickness
Anoxia
Humans
Societies, Medical
PubMed ID
19775221 View in PubMed
Less detail

Abnormal control of ventilation in high-altitude pulmonary edema.

https://arctichealth.org/en/permalink/ahliterature3383
Source
J Appl Physiol. 1988 Mar;64(3):1268-72
Publication Type
Article
Date
Mar-1988
Author
P H Hackett
R C Roach
R B Schoene
G L Harrison
W J Mills
Author Affiliation
Denali Medical Research Project, Center for High Latitude Health Research, University of Alaska, Anchorage 99508.
Source
J Appl Physiol. 1988 Mar;64(3):1268-72
Date
Mar-1988
Language
English
Publication Type
Article
Keywords
Adult
Altitude
Anoxemia - physiopathology
Anoxia - physiopathology
Female
Humans
Male
Oxygen - metabolism
Oxygen Inhalation Therapy
Pulmonary Edema - physiopathology - therapy
Respiration
Abstract
We wished to determine the role of hypoxic chemosensitivity in high-altitude pulmonary edema (HAPE) by studying persons when ill and upon recovery. We studied seven males with HAPE and seventeen controls at 4,400 m on Mt. McKinley. We measured ventilatory responses to both O2 breathing and progressive poikilocapnic hypoxia. Hypoxic ventilatory response (HVR) was described by the slope relating minute ventilation to percent arterial O2 saturation (delta VE/delta SaO2%). HAPE subjects were quite hypoxemic (SaO2% 59 +/- 6 vs. 85 +/- 1, P less than 0.01) and showed a high-frequency, low-tidal-volume pattern of breathing. O2 decreased ventilation in controls (-20%, P less than 0.01) but not in HAPE subjects. The HAPE group had low HVR values (0.15 +/- 0.07 vs. 0.54 +/- 0.08, P less than 0.01), although six controls had values in the same range. The three HAPE subjects with the lowest HVR values were the most hypoxemic and had a paradoxical increase in ventilation when breathing O2. We conclude that a low HVR plays a permissive rather than causative role in the pathogenesis of HAPE and that the combination of extreme hypoxemia and low HVR may result in hypoxic depression of ventilation.
PubMed ID
3366741 View in PubMed
Less detail

[Adaptive reactions of students from mountain and plain regions of Latin America to conditions of middle Russia].

https://arctichealth.org/en/permalink/ahliterature184082
Source
Fiziol Zh. 2003;49(3):150-5
Publication Type
Article
Date
2003
Author
N V Ermakova
Author Affiliation
Russian Peoples' Friendship University, Moscow.
Source
Fiziol Zh. 2003;49(3):150-5
Date
2003
Language
Russian
Publication Type
Article
Keywords
Adaptation, physiological - physiology
Adult
Altitude
Anthropometry
Cardiovascular Physiological Phenomena
Humans
Latin America - ethnology
Respiratory Physiological Phenomena
Russia
Students
Abstract
This article contains results of the comparative study of the functional state of respiratory and cardiovascular systems of almost healthy students (man) of age 19-22, inhabitants of mountain and plain regions of Latin America during their adaptation to the conditions of middle Russia. We have established that there are reliable distinctions in the functional state of cardio-respiratory system of students from mountain and plain regions of Latin America. So for representatives of mountain regions of LA were typical higher indicators of vital capacity, permeability of large and medium bronchial tubes, stroke volume, lower indicators of heart rate, systolic arterial pressure, myocard tension index, but higher coefficient of myocard efficiency than for inhabitants the plain. Considerable distinctions have been observed also in the intercommunication between different indicators. There have been marked considerable correlation connections between small bronchial tubes permeability and cardiovascular system indicators for plain inhabitants. For mountain regions inhabitants almost every indicator of bronchial tubes permeability correlate reliably with vital capacity, but didn't correlate with hemodynamics indicators.
PubMed ID
12918265 View in PubMed
Less detail

Advances in high-altitude medicine and hypoxic physiology in China.

https://arctichealth.org/en/permalink/ahliterature295218
Source
A sponsored supplement to Science. 69 p.
Publication Type
Journal
Date
2012
1 8/2/12 1:49 PM Introductions 3.... High-Altitude Medical Research in China: Importance and Relevance Wu Tianyi, M.D. 4.... Research Atop the Roof of the World Alan Leshner, Ph.D. High-Altitude Medicine 1 Table of Contents 6.... A Unique Challenge in High-Altitude Medicine
  1 document  
Source
A sponsored supplement to Science. 69 p.
Date
2012
Language
English
Publication Type
Journal
File Size
36208366
Keywords
China
Hypoxia
Hypoxic physiology
High-altitude medicine
Documents

BIBMS_booklet_hires.pdf

Read PDF Online Download PDF
Less detail

Aerobic exercise capacity at sea level and at altitude in Kenyan boys, junior and senior runners compared with Scandinavian runners.

https://arctichealth.org/en/permalink/ahliterature50148
Source
Scand J Med Sci Sports. 1995 Aug;5(4):209-21
Publication Type
Article
Date
Aug-1995
Author
B. Saltin
H. Larsen
N. Terrados
J. Bangsbo
T. Bak
C K Kim
J. Svedenhag
C J Rolf
Author Affiliation
August Krogh Institute, University of Copenhagen, Denmark.
Source
Scand J Med Sci Sports. 1995 Aug;5(4):209-21
Date
Aug-1995
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Altitude
Ammonia - blood
Body Weight
Comparative Study
Denmark
Efficiency
Energy Metabolism
Exercise - physiology
Exercise Tolerance - physiology
Heart rate
Hemoglobins - analysis
Humans
Kenya
Lactates - blood
Male
Oxygen Consumption - physiology
Research Support, Non-U.S. Gov't
Respiration
Running - education - physiology
Sweden
Walking - physiology
Abstract
The aim of this study was to characterize Kenyan runners in regard to their oxygen uptake and blood and ammonia responses when running. Untrained Kenyan boys (14.2 +/- 0.2 years) and Scandinavian runners were included for comparison. The studies were performed at altitude (approximately 2.000 m.a.s.l.) and, for several Kenyan and Scandinavian runners, at sea level as well. At altitude sedentary adolescent Kenyan boys had a mean maximal oxygen uptake (VO2max) of 47 (44-51) ml.kg-1.min-1, whereas similarly aged boys regularly walking or running but not training for competition reached above 62 (58-71) ml.kg-1.min-1 in VO2max. Kenyan runners in active training had 68 +/- 1.4 ml.kg-1.min-1 at altitude and 79.9 +/- 1.4 ml.kg-1.min-1 at sea level, with individuals reaching 85 ml.kg-1.min-1. The best Scandinavian runners were not significantly different from the Kenyan runners in VO2max both at altitude and at sea level, but none of the Scandinavians reached as high individual values as observed for some Kenyan runners. The running efficiency, determined as the oxygen cost at a given running speed, was less in the Kenyan runners, and the difference became more pronounced when body weight was expressed in ml.kg-0.75 min-1. Blood lactate concentration was in general lower in the Kenyan than in the Scandinavian runners, and the Kenyans also had extremely low ammonia accumulation in the blood even at very high exercise intensities. It is concluded that it is the physical activity during childhood, combined with intense training as teenagers that brings about the high VO2max observed in some Kenyan runners. Their high aerobic capacity, as well as their good running economy, makes them such superior runners. In addition, their low blood lactate and ammonia accumulation in blood when running may also be contributing factors.
PubMed ID
7552766 View in PubMed
Less detail

Aerobic fitness influences the response of maximal oxygen uptake and lactate threshold in acute hypobaric hypoxia.

https://arctichealth.org/en/permalink/ahliterature50162
Source
Int J Sports Med. 1995 Feb;16(2):78-81
Publication Type
Article
Date
Feb-1995
Author
P. Koistinen
T. Takala
V. Martikkala
J. Leppäluoto
Author Affiliation
Health Centre Hospital of Oulu, Finland.
Source
Int J Sports Med. 1995 Feb;16(2):78-81
Date
Feb-1995
Language
English
Publication Type
Article
Keywords
Acute Disease
Adult
Aerobiosis
Altitude
Anaerobic Threshold - physiology
Anoxia - blood - physiopathology
Exercise Test
Female
Heart Rate - physiology
Hockey - physiology
Humans
Lactates - blood
Male
Oxygen - blood
Oxygen Consumption - physiology
Physical Fitness - physiology
Respiration - physiology
Skiing - physiology
Ventilation-Perfusion Ratio
Abstract
We studied 12 highly trained athletes, 6 male ice-hockey players and 6 cross-country skiers (2 females, 4 males). All of them participated in a maximal electrically braked bicycle ergometer test in a hypobaric chamber at the simulated altitude of 3000m (520 mmHg) and in normobaric conditions two days apart in random order. The maximal oxygen uptake was 57.4 +/- 7.1 (SD) ml/kg/min in normobaria (VO2maxnorm) and 46.6 +/- 4.9 (SD) ml/kg/min in hypobaric hypoxia (VO2maxhyp). The decrease in maximal oxygen uptake (delta VO2max) at the simulated altitude of 3000m correlated significantly (p
PubMed ID
7751080 View in PubMed
Less detail

[Age-dependent characteristics of blood plasma oxidative and antioxidative reactions to the hypobaric hypoxia and different duration of the photoperiod]

https://arctichealth.org/en/permalink/ahliterature81093
Source
Fiziol Zh. 2006;52(3):84-9
Publication Type
Article
Date
2006
Author
Iasins'ka O V
Source
Fiziol Zh. 2006;52(3):84-9
Date
2006
Language
Ukrainian
Publication Type
Article
Keywords
Aging - blood
Altitude
Animals
Anoxia - blood
Atmospheric Pressure
Catalase - blood
Lipid Peroxides - blood
Male
Photoperiod
Rats
Superoxide Dismutase - blood
Abstract
The effect of hypobaric hypoxia (6 hours everyday 7 days) under different duration of the photoperiod on oxidative (malonic aldehide and dienal conjugates) and antioxidative (catalase and superoxide dismutase activity) systems in the blood plasma of adult and infantile albino male rats were investigated. It is concluded that there is an age-dependent reaction of oxidative and antioxidative systems to the combined action of hypobaric hypoxia and different duration of the photoperiod. Reactions of pro- and antioxidative systems of adult and infantile rats were approximately the same under the conditions of a long-term darkness-and hypoxia but in the infants they were less manifested under the combined action of hypoxia and natural light or long-term lightening. Hypoxia combined with all varieties of photoperiod activate antioxidative system in both age groups but only in infantile rats the process of peroxidation was reducing.
PubMed ID
16909761 View in PubMed
Less detail

[A genetic and demographic study of Dagestan highland populations and migrants to the lowlands. The relationship between levels of consanguinity, homozygosity and physiologic sensitivity].

https://arctichealth.org/en/permalink/ahliterature213559
Source
Genetika. 1996 Jan;32(1):93-102
Publication Type
Article
Date
Jan-1996
Author
K B Bulaeva
T A Pavlova
S M Charukhilova
I E Bodia
G G Guseinov
S Kh Akhkuev
Source
Genetika. 1996 Jan;32(1):93-102
Date
Jan-1996
Language
Russian
Publication Type
Article
Keywords
Adaptation, Physiological
Altitude
Consanguinity
Dagestan
Demography
Environmental health
Female
Genetics, Population
Homozygote
Humans
Male
Transients and Migrants
Abstract
This is a continuation of a series of papers devoted to studying the genetic mechanisms of adaptation in migrants from isolated highland populations of Dagestan to new ecological conditions (lowlands). This paper describes the main results of studying the relationship between levels of inbreeding, homozygosity, and physiological sensitivity. Earlier, we found that decreased resistance to changing environmental factors in migrants to lowlands from the Dagestan highlands was connected with their high level of homozygosity. The data obtained allow us to assume that missing links in this chain of events include, in addition to parameters of inbreeding level, parameters of neurophysiological sensitivity, including absolute and differential sensitivity of various analyzers sensory systems, which are from 65 to 75% genetically determined. Migrants from highland auls (villages) to lowlands exhibited a decreased rate of sensomotor reactions in response to light and sound of various intensities, as well as decreased differential color sensitivity in the long-, medium-, and short-wave ranges of the spectrum, compared to highlanders. The results suggest the selective mortality of migrants from highlands to lowlands during adaptation to new conditions. Those migrants who dies were characterized by specific gene complexes that determined the characteristic features of expression of a number of interrelated polymorphic and quantitative traits. Thus, the high levels of homozygosity and inbreeding were accompanied by a greater neurophysiological sensitivity and lower indices of body weight and height.
PubMed ID
8647428 View in PubMed
Less detail

[A genetic epidemiological study of arterial hypertension in an isolated mountain area of Dagestan].

https://arctichealth.org/en/permalink/ahliterature213134
Source
Ter Arkh. 1996;68(12):64-6
Publication Type
Article
Date
1996
Author
G G Guseinov
I A Shamov
K B Bulaeva
Source
Ter Arkh. 1996;68(12):64-6
Date
1996
Language
Russian
Publication Type
Article
Keywords
Alleles
Altitude
Consanguinity
Dagestan - epidemiology
Female
Humans
Hypertension - ethnology - genetics
Incidence
Male
Molecular Epidemiology
Phenotype
Prevalence
Questionnaires
Rural Population - statistics & numerical data
Abstract
Hereditary factors of arterial hypertension were evaluated genetically and epidemiologically in the study of an isolated population of Dagestan with high inbreeding. High prevalence of arterial hypertension was found. Its highest morbidity was found in native population of Tukhums characterized also by the highest inbreeding.
PubMed ID
9054045 View in PubMed
Less detail

[Age-related characteristics of vascular system function in bronchial asthma patients being treated in an alpine climate].

https://arctichealth.org/en/permalink/ahliterature242173
Source
Vopr Kurortol Fizioter Lech Fiz Kult. 1983 Mar-Apr;(2):39-41
Publication Type
Article

303 records – page 1 of 31.