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Impact of early systemic lupus erythematosus on work disability-results from the Finnish nationwide register 2000-2007.

https://arctichealth.org/en/permalink/ahliterature294999
Source
Clin Rheumatol. 2018 May; 37(5):1413-1416
Publication Type
Journal Article
Date
May-2018
Author
Pia Elfving
Kari Puolakka
Vappu Rantalaiho
Hannu Kautiainen
Lauri J Virta
Oili Kaipiainen-Seppänen
Author Affiliation
Department of Medicine, Kuopio University Hospital, P.O. Box 100, 70029 KYS, Kuopio, Finland. pia.elfving@kuh.fi.
Source
Clin Rheumatol. 2018 May; 37(5):1413-1416
Date
May-2018
Language
English
Publication Type
Journal Article
Keywords
Adolescent
Adult
Female
Finland - epidemiology
Humans
Incidence
Lupus Erythematosus, Systemic - epidemiology
Male
Middle Aged
Registries
Sick Leave - statistics & numerical data
Young Adult
Abstract
Objectives of this study were to examine work disability (WD) and its leading causes in incident SLE patients. Data were derived from the Finnish nationwide registries to identify all non-retired, 18 to 64-year-old incident SLE patients between 2000 and 2007. Sick benefits and WD pensions and the causes for them were monitored until the end of 2008. A total of 446 working-aged, incident SLE patients available for work force (mean age 42?±?13 years, 89% females) were found. During the follow-up (median 5.3 years), WD pension was granted to 27 patients. The most common cause was SLE itself (14 patients, 52%), with cumulative incidence of 3.4% (95% CI 1.9 to 5.8) in 5 years and 5.0% (95% CI 3.0 to 8.5) in 8 years, followed by musculoskeletal and psychiatric causes. The age- and sex- adjusted incidence ratio for WD pension in SLE patients due to any cause was 5.4 (95% CI 3.7 to 7.9) compared to the Finnish population. The mean number of WD days was 32 (95% CI 28 to 35) per patient-year among all SLE patients during the follow-up. The study concludes that SLE patients have an increased risk for WD already in early course of the disease.
Notes
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PubMed ID
29541950 View in PubMed
Less detail

Anticholinergic drug use and its association with self-reported symptoms among older persons with and without diabetes.

https://arctichealth.org/en/permalink/ahliterature298928
Source
J Clin Pharm Ther. 2019 Apr; 44(2):229-235
Publication Type
Journal Article
Date
Apr-2019
Author
Niina-Mari Inkeri
Merja Karjalainen
Maija Haanpää
Hannu Kautiainen
Juha Saltevo
Pekka Mäntyselkä
Miia Tiihonen
Author Affiliation
School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
Source
J Clin Pharm Ther. 2019 Apr; 44(2):229-235
Date
Apr-2019
Language
English
Publication Type
Journal Article
Keywords
Aged
Aged, 80 and over
Cholinergic Antagonists - adverse effects - therapeutic use
Cohort Studies
Cross-Sectional Studies
Diabetes Mellitus - epidemiology
Female
Finland
Humans
Independent living
Male
Practice Patterns, Physicians' - statistics & numerical data
Primary Health Care
Self Report
Surveys and Questionnaires
Abstract
Anticholinergic drug use has been associated with a risk of central and peripheral adverse effects. There is a lack of information on anticholinergic drug use in persons with diabetes. The aim of this study is to investigate anticholinergic drug use and the association between anticholinergic drug use and self-reported symptoms in older community-dwelling persons with and without diabetes.
The basic population was comprised of Finnish community-dwelling primary care patients aged 65 and older. Persons with diabetes were identified according to the ICD-10 diagnostic codes from electronic patient records. Two controls adjusted by age and gender were selected for each person with diabetes. This cross-sectional study was based on electronic primary care patient records and a structured health questionnaire. The health questionnaire was returned by 430 (81.6%) persons with diabetes and 654 (73.5%) persons without diabetes. Data on prescribed drugs were obtained from the electronic patient records. Anticholinergic drug use was measured according to the Anticholinergic Risk Scale. The presence and strength of anticholinergic symptoms were asked in the health questionnaire.
The prevalence of anticholinergic drug use was 8.9% in the total study cohort. There were no significant differences in anticholinergic drug use between persons with and without diabetes. There was no consistent association between anticholinergic drug use and self-reported symptoms.
There is no difference in anticholinergic drug use in older community-dwelling persons with and without diabetes. Anticholinergic drug use should be considered individually and monitored carefully.
PubMed ID
30315583 View in PubMed
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Older persons with signs of frailty in a home-based physical exercise intervention: baseline characteristics of an RCT.

https://arctichealth.org/en/permalink/ahliterature299053
Source
Aging Clin Exp Res. 2019 Apr 02; :
Publication Type
Journal Article
Date
Apr-02-2019
Author
Sara Suikkanen
Paula Soukkio
Kaisu Pitkälä
Sanna Kääriä
Hannu Kautiainen
Sarianna Sipilä
Katriina Kukkonen-Harjula
Markku Hupli
Author Affiliation
Rehabilitation, South Karelia Social and Health Care District, Valto Käkelän katu 3, 53130, Lappeenranta, Finland. sara.suikkanen@eksote.fi.
Source
Aging Clin Exp Res. 2019 Apr 02; :
Date
Apr-02-2019
Language
English
Publication Type
Journal Article
Abstract
Increasing the level of physical activity among persons with signs of frailty improves physical functioning. There is a lack of long-term supervised physical exercise intervention studies including a validated definition of frailty.
To present baseline characteristics of persons with signs of frailty participating in a randomized long-term home-based physical exercise trial (HIPFRA), and to study associations between the severity of frailty, functional independence and health-related quality-of-life (HRQoL).
Three hundred persons,?=?65 years old and with signs of frailty (assessed by Fried´s phenotype criteria) were recruited from South Karelia, Finland and randomized to a 12-month physiotherapist-supervised home-based physical exercise program (n?=?150), and usual care (n?=?150). Assessments at the participants' homes at baseline, and after 3, 6 and 12 months included the Short Physical Performance Battery (SPPB), the Functional Independence Measure (FIM), HRQoL (15D) and the Mini-Mental State Examination (MMSE).
Eligibility was screened among 520 persons; 300 met the inclusion criteria and were randomized. One person withdrew consent after randomization. A majority (75%) were women, 182 were pre-frail and 117 frail. The mean age was 82.5 (SD 6.3) years, SPPB 6.2 (2.6), FIM 108.8 (10.6) and MMSE 24.4 (3.1) points, with no significant differences between the study groups. Inverse associations between the severity of frailty vs. FIM scores and HRQoL (p?
PubMed ID
30941731 View in PubMed
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Hemoglobin level and lipoprotein particle size.

https://arctichealth.org/en/permalink/ahliterature294299
Source
Lipids Health Dis. 2018 Jan 10; 17(1):10
Publication Type
Journal Article
Date
Jan-10-2018
Author
Päivi Hämäläinen
Juha Saltevo
Hannu Kautiainen
Pekka Mäntyselkä
Mauno Vanhala
Author Affiliation
Department of Internal Medicine, Tampere University Hospital, Teiskontie 35, 33521, Tampere, Finland. Paivi.o.hamalainen@pshp.fi.
Source
Lipids Health Dis. 2018 Jan 10; 17(1):10
Date
Jan-10-2018
Language
English
Publication Type
Journal Article
Keywords
Aged
Body mass index
Cross-Sectional Studies
Diabetes Mellitus - diagnosis
Female
Finland
Hemoglobins - metabolism
Humans
Insulin Resistance
Lipoproteins, HDL - blood
Lipoproteins, LDL - blood
Lipoproteins, VLDL - blood
Male
Metabolic Syndrome - diagnosis
Middle Aged
Particle Size
Risk factors
Triglycerides - blood
Abstract
Alterations in lipoprotein size are associated with increased cardiovascular disease risk. Higher hemoglobin levels may indicate a higher risk of atherosclerosis and was previously associated with obesity, metabolic syndrome, and insulin resistance. No previous studies have investigated an association between hemoglobin concentration and lipoprotein particle size.
We conducted a population-based, cross-sectional study of 766 Caucasian, middle-aged subjects (341 men and 425 women) born in Pieksämäki, Finland, who were categorized into five age groups. The concentrations and sizes of lipoprotein subclass particles were analyzed by high-throughput nuclear magnetic resonance (NMR) spectroscopy.
Larger very low density lipoprotein (VLDL) particle diameter was associated with higher hemoglobin concentrations in men (p = 0.003). There was a strong relationship between smaller high density lipoprotein (HDL) particle size and higher hemoglobin concentration in both men and women as well as with smaller low density lipoprotein (LDL) particle size and higher hemoglobin concentration in men and women (p 
Notes
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PubMed ID
29321013 View in PubMed
Less detail

Physical and mental health factors associated with work engagement among Finnish female municipal employees: a cross-sectional study.

https://arctichealth.org/en/permalink/ahliterature292218
Source
BMJ Open. 2017 Oct 05; 7(10):e017303
Publication Type
Journal Article
Date
Oct-05-2017
Author
Veera Veromaa
Hannu Kautiainen
Päivi Elina Korhonen
Author Affiliation
Department of Family Medicine, Institute of Clinical Medicine, University of Turku and Turku University Hospital, Turku, Finland.
Source
BMJ Open. 2017 Oct 05; 7(10):e017303
Date
Oct-05-2017
Language
English
Publication Type
Journal Article
Keywords
Adult
Body mass index
Cardiovascular Diseases - epidemiology - prevention & control
Cross-Sectional Studies
Exercise
Female
Finland
Healthy Diet
Humans
Linear Models
Longitudinal Studies
Mental health
Middle Aged
Multivariate Analysis
Psychology
Risk assessment
Risk factors
Work Engagement
Abstract
Work engagement is related to mental health, but studies of physical health's association with work engagement are scarce. This study aims to evaluate the relationship between physical health, psychosocial risk factors and work engagement among Finnish women in municipal work units.
A cross-sectional study was conducted in 2014 among 726 female employees from 10 municipal work units of the city of Pori, Finland. Work engagement was assessed with the nine-item Utrecht Work Engagement Scale. The American Heart Association's concept of ideal cardiovascular health (CVH) was used to define physical health (non-smoking, body mass index
Notes
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PubMed ID
28982827 View in PubMed
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Psychiatric diagnosis in primary care patients with increased depressive symptoms.

https://arctichealth.org/en/permalink/ahliterature300018
Source
Nord J Psychiatry. 2019 Apr; 73(3):195-199
Publication Type
Journal Article
Date
Apr-2019
Author
Satu Kotiaho
Katariina Korniloff
Mauno Vanhala
Hannu Kautiainen
Hannu Koponen
Tiina Ahonen
Pekka Mäntyselkä
Author Affiliation
a School of Medicine, General Practice , University of Eastern Finland , Kuopio , Finland.
Source
Nord J Psychiatry. 2019 Apr; 73(3):195-199
Date
Apr-2019
Language
English
Publication Type
Journal Article
Keywords
Adult
Aged
Comorbidity
Depressive Disorder - diagnosis - psychology
Female
Finland
Humans
Male
Mental Disorders - psychology
Middle Aged
Primary Health Care - statistics & numerical data
Psychiatric Status Rating Scales
Abstract
Screening of depression has been recommended in primary care and Beck's 21-item Depression Inventory (BDI-21) is a commonly used tool for screening. Depression has been shown to be frequently accompanied by comorbidities.
This study aimed to analyze the characteristics, psychiatric diagnoses, and psychiatric comorbidity of primary care patients who have been screened for depression and referred to a depression nurse.
The study subjects were primary care patients aged = 35 years with depressive symptoms (BDI-21?>?9). Their psychiatric diagnosis were based on a diagnostic interview (Mini-International Neuropsychiatric Interview; M.I.N.I.) conducted by a trained study nurse.
Of the 705 study subjects, 617 (87.5%) had at least one and 66.1% had at least two psychiatric diagnoses. The most common diagnosis was depression (63.4%). The next most common diagnoses were generalized anxiety disorder (GAD) (48.1%) and panic disorder (22.8%). Only 8.8% of the study subjects had depression without other psychiatric disorders. Ten percent of the subjects had both depression and a generalized anxiety disorder (GAD). Also other psychiatric comorbidities were common. Age was inversely associated with the psychiatric diagnosis in the M.I.N.I.
This study suggests that most of the primary care patients with increased depressive symptoms have a psychiatric disorder. Although depression is the most common diagnosis, there are several other concurrent psychiatric comorbidities. Therefore, diagnostic assessment of primary care patients with a screening score over 9 in the BDI-21 should be reconsidered.
PubMed ID
30929594 View in PubMed
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Effects of 12-month home-based physiotherapy on duration of living at home and functional capacity among older persons with signs of frailty or with a recent hip fracture - protocol of a randomized controlled trial (HIPFRA study).

https://arctichealth.org/en/permalink/ahliterature295229
Source
BMC Geriatr. 2018 Oct 01; 18(1):232
Publication Type
Journal Article
Date
Oct-01-2018
Author
Paula Soukkio
Sara Suikkanen
Sanna Kääriä
Hannu Kautiainen
Sarianna Sipilä
Katriina Kukkonen-Harjula
Markku Hupli
Author Affiliation
Rehabilitation, South Karelia Social and Health Care District, Valto Käkelän katu 3, FI-53130, Lappeenranta, Finland. paula.soukkio@eksote.fi.
Source
BMC Geriatr. 2018 Oct 01; 18(1):232
Date
Oct-01-2018
Language
English
Publication Type
Journal Article
Abstract
Health concerns, such as frailty and osteoporotic fractures decrease functional capacity and increase use of health and social care services in the aging population. The ability to continue living at home is dependent on functional capacity, which can be enhanced by rehabilitation. We study the effects of a 12-month home-based physiotherapy program with 12-month follow-up on duration of living at home, functional capacity, and the use of social and health care services among older persons with signs of frailty, or with a recently operated hip fracture.
This is a non-blinded, parallel group, randomized controlled trial performed in South Karelia Social and Health Care District, Finland (population 131,000). Three hundred community-dwelling older persons with signs of frailty (age?=?65) and 300 persons with a recent hip fracture (age?=?60) will be recruited. Frailty is screened by FRAIL questionnaire and verified by modified Fried's frailty criteria. Both patient groups will be randomized separately to a physiotherapy and a usual care arm. Individualized, structured and progressive physiotherapy will be carried out for 60 min, twice a week for 12 months at the participant's home. The primary outcome at 24 months is duration of living at home. Our hypothesis is that persons assigned to the physiotherapy arm will live at home for six months longer than those in the usual care arm. Secondary outcomes are functional capacity, frailty status, health-related quality-of-life, falls, use and costs of social and health care services, and mortality. Assessments, among others Short Physical Performance Battery, Functional Independence Measure, Mini Nutritional Assessment, and Mini-Mental State Examination will be performed at the participant's home at baseline, 3, 6, and 12 months. Register data on the use and costs of social and health care services, and mortality will be monitored for 24 months.
Our trial will provide new knowledge on the potential of intensive, long-term home-based physiotherapy among older persons at risk for disabilities, to enhance functional capacity and thereby to postpone the need for institutional care, and diminish the use of social and health care services.
ClinicalTrials.gov Identifier: NCT02305433 , Registered Nov 28, 2014.
Notes
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PubMed ID
30285645 View in PubMed
Less detail

Regular physical exercise before entering military service may protect young adult men from fatigue fractures.

https://arctichealth.org/en/permalink/ahliterature301920
Source
BMC Musculoskelet Disord. 2019 Mar 25; 20(1):126
Publication Type
Journal Article
Date
Mar-25-2019
Author
Harri Pihlajamäki
Mickael Parviainen
Heikki Kyröläinen
Hannu Kautiainen
Ilkka Kiviranta
Author Affiliation
Department of Orthopaedics and Traumatology, Seinäjoki Central Hospital, Seinäjoki and University of Helsinki, Helsinki, Finland. harri.pihlajamaki@helsinki.fi.
Source
BMC Musculoskelet Disord. 2019 Mar 25; 20(1):126
Date
Mar-25-2019
Language
English
Publication Type
Journal Article
Keywords
Adolescent
Adult
Cohort Studies
Exercise - physiology
Finland - epidemiology
Follow-Up Studies
Fractures, Stress - diagnosis - epidemiology - prevention & control
Humans
Male
Military Medicine - methods
Military Personnel
Random Allocation
Young Adult
Abstract
Bone stress fractures are overuse injuries commonly encountered in sports and military medicine. Some fatigue fractures lead to morbidity and loss of active, physically-demanding training days. We evaluated the incidence, anatomical location, risk factors, and preventive measures for fatigue fractures in young Finnish male conscripts.
Five cohorts of 1000 men performing military service, classified according to birth year (1969, 1974, 1979, 1984, 1989), were analysed. Each conscript was followed for his full military service period (180?days for conscripts with rank and file duties, 270?days for those with special training, 362?days for officers and highly trained conscripts). Data, including physical activity level, were collected from a standard pre-information questionnaire and from the garrisons' healthcare centre medical reports. Risk factor analysis included the conscripts' service class (A, B), length of military service, age, height, weight, body mass index, smoking, education, previous diseases, injuries, and subjective symptoms, as well as self-reports of physical activity before entering the service using a standard military questionnaire.
Fatigue fractures occurred in 44 (1.1%) of 4029 men, with an incidence of 1.27 (95% confidence interval: 0.92-1.70) per 1000 follow-up months, and mostly (33/44, 75%) occurred at the tibial shaft or metatarsals. Three patients experienced two simultaneous stress fractures in different bones. Most fatigue fractures occurred in the first 3?months of military service. Conscripts with fatigue fractures lost a total of 1359 (range 10-77) active military training days due to exemptions from duty. Conscripts reporting regular (>?2 times/week) physical activity before entering the military had significantly fewer (p?=?0.017) fatigue fractures. Regular physical activity before entering the service was the only strong explanatory, protective factor in the model [IRR?=?0.41 (95% CI: 0.20 to 0.85)]. The other measured parameters did not contribute significantly to the incidence of stress fractures.
Regular and recurrent high-intensity physical activity before entering military service seems to be an important preventive measure against developing fatigue fractures. Fatigue fractures should be considered in conscripts seeking medical advice for complaints of musculoskeletal pain, and taken into consideration in planning military and other physical training programs.
PubMed ID
30909910 View in PubMed
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The mortality rate and causes of death among juvenile idiopathic arthritis patients in Finland.

https://arctichealth.org/en/permalink/ahliterature300281
Source
Clin Exp Rheumatol. 2019 May-Jun; 37(3):508-511
Publication Type
Journal Article
Author
Minna Susanna Kyllönen
Hannu Kautiainen
Kari Puolakka
Paula Vähäsalo
Author Affiliation
Department of Internal Medicine and Medical Research Centre, University of Oulu and Oulu University Hospital; and PEDEGO Research Unit, University of Oulu, Finland. mikyllon@student.oulu.fi.
Source
Clin Exp Rheumatol. 2019 May-Jun; 37(3):508-511
Language
English
Publication Type
Journal Article
Keywords
Adolescent
Adult
Arthritis, Juvenile - mortality
Case-Control Studies
Cause of Death
Child
Female
Finland
Humans
Male
Proportional Hazards Models
Registries
Young Adult
Abstract
To explore mortality rates and causes of death in juvenile idiopathic arthritis (JIA) patients in Finland compared with the general population.
All incident patients with JIA (age
PubMed ID
30767877 View in PubMed
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Determinants of sickness absence rate among Finnish municipal employees.

https://arctichealth.org/en/permalink/ahliterature300292
Source
Scand J Prim Health Care. 2019 Mar; 37(1):3-9
Publication Type
Journal Article
Date
Mar-2019
Author
Tiina Vuorio
Sakari Suominen
Hannu Kautiainen
Päivi Korhonen
Author Affiliation
a Department of Family Medicine, Institute of Clinical Medicine , University of Turku and Turku University Hospital , Turku , Finland.
Source
Scand J Prim Health Care. 2019 Mar; 37(1):3-9
Date
Mar-2019
Language
English
Publication Type
Journal Article
Keywords
Absenteeism
Adult
Chronic Disease
Cross-Sectional Studies
Educational Status
Female
Finland
Humans
Male
Middle Aged
Multivariate Analysis
Occupations
Risk factors
Sick Leave
Surveys and Questionnaires
Abstract
In addition to acute health problems, various aspects of health behavior, work-related and sociodemographic factors have been shown to influence the rate of sickness absence. The aim of this study was to concomitantly examine factors known to have an association with absenteeism. We hypothesized the prevalence of chronic diseases being the most important factor associated with sickness absence.
A cross-sectional study.
Occupational health care in the region of Pori, Finland.
671 municipal employees (89% females) with a mean age of 49 (SD 10) years. Information about the study subjects was gathered from medical records, by physical examination and questionnaires containing information about physical and mental health, health behavior, work-related and sociodemographic factors. The number of sickness absence days was obtained from the records of the city of Pori.
The relationship of absenteeism rate with sociodemographic, health- and work-related risk factors.
In the multivariate analysis, the mean number of chronic diseases (IRR 1.24, 95% CI 1.13 to 1.36), work ability (IRR 0.83, 95% CI 0.76 to 0.91), and length of years in education (IRR 0.90, 95% CI 0.85 to 0.95) remained as independent factors associated with absenteeism.
According to our results, chronic diseases, self-perceived work ability and length of years in education are the most important determinants of the rate of sickness absence. This implies that among working-aged people the treatment of chronic medical conditions is also worth prioritizing, not only to prevent complications, but also to avoid sickness absences. KEY POINTS Various sociodemographic, health- and work- related risk factors have been shown to influence sickness absence. The study aimed to find the most important determinants of absenteeism among several known risk factors in Finnish municipal employees. Chronic diseases, self-perceived work ability and education years remained as the most important determinants of sickness absence rates. Treatment of chronic medical conditions should be prioritized in order to reduce sickness absence rate.
PubMed ID
30689483 View in PubMed
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