While kidney paired donation (KPD) enables the utilization of living donor kidneys from healthy and willing donors incompatible with their intended recipients, the strategy poses complex challenges that have limited its adoption in United States and Canada. A consensus conference was convened March 29-30, 2012 to address the dynamic challenges and complexities of KPD that inhibit optimal implementation. Stakeholders considered donor evaluation and care, histocompatibility testing, allocation algorithms, financing, geographic challenges and implementation strategies with the goal to safely maximize KPD at every transplant center. Best practices, knowledge gaps and research goals were identified and summarized in this document.
Comment In: Am J Transplant. 2013 Aug;13(8):222823834021
In June 2015, the fourth European Workshop on Plant Chromatin took place in Uppsala, Sweden, bringing together 80 researchers studying various aspects of plant chromatin and epigenetics. The intricate relationships between plant chromatin dynamics and gene expression change, chromatin organization within the plant cell nucleus, and the impact of chromatin structure on plant development were discussed. Among the main highlights of the meeting were an ever-growing list of newly identified players in chromatin structure establishment and the development of novel tools and approaches to foster our understanding of chromatin-mediated gene regulation, taking into account the context of the plant cell nucleus and its architecture. In this report, we summarize some of the main advances and prospects of plant chromatin research presented at this meeting.
The structural organization of the nucleus and its content has drawn increasing interest in recent years, as it is has become evident that the spatial and temporal arrangement of the genome and associated structures plays a crucial role in transcriptional regulation and numerous other functions. Shining light on the dynamic nature of this organization, along with the processes controlling it, were the topics of the Wenner-Gren Foundations international symposium "Nuclear Dynamics: Design (and) Principles." The meeting, organized by Piorgiogio Percipalle, Maria Vartiainen, Neus Visa, and Ann-Kristin Östlund-Farrants, brought over 60 participants, including 20 international speakers, to Stockholm, Sweden from August 19-22, 2015 to share the latest developments in the field. Given the unpublished nature of many of the talks, we have focused on covering the discussed topics and highlighting the latest trends in this exciting and rapidly evolving field.
We had the privilege of joining over 5,000 nurses attending the 24th Congress of the International Council of Nurses, held for the first time on the African continent in Durban, South Africa. The Congress inspired us to reflect on how leadership and policy directions in Canadian nursing resonate with global health challenges and opportunities. Dynamic plenary speakers from African countries inspired the conference theme: Leading Change--Building Healthy Nations. Ensuing discussions signalled shifting priorities and urgent implications for nursing leadership and programs of research in Canada and worldwide, in areas of primary healthcare renewal, nursing health human resources sustainability and health interventions for the achievement of the United Nations Millennium Development Goals (MDGs) (United Nations 2009; WHO 2008). Sharing challenges with nurses worldwide, Canadian nurses are privileged with the resources to address these challenges (CNA 2008; WHO 2008). Our experience at the Congress prompted the question: How must Canadian nurses reshape leadership priorities and agendas not only in the Canadian context, but also in the mutual interests of health for all? Reflecting upon the themes of the Congress and the leadership role of Canadian nurses, we identify three interconnected priorities: Invest our hearts, souls and resources in primary healthcare renewal. Grapple with the complexity of an equitable and sustainable global nursing human resources system. Ensure a lens of social justice through leadership, research and education for the achievement of the MDGs.