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Frequency and characteristics of recurrent major depressed patients with unimpaired executive functions.

https://arctichealth.org/en/permalink/ahliterature45662
Source
World J Biol Psychiatry. 2005;6(1):36-44
Publication Type
Article
Date
2005
Author
Kirsten I Stordal
Astri J Lundervold
Arnstein Mykletun
Arve Asbjørnsen
Eva Biringer
Jens Egeland
Asa Hammar
Nils Inge Landrø
Atle Roness
Bjørn Rishovd Rund
Kjetil Sundet
Anders Lund
Author Affiliation
Department of Clinical Medicine, Section of Psychiatry, University of Bergen, Bergen, Norway. kirsten.irene.stordal@helse-bergen.no
Source
World J Biol Psychiatry. 2005;6(1):36-44
Date
2005
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Aptitude
Cognition Disorders - classification - diagnosis - epidemiology - therapy
Cross-Sectional Studies
Depressive Disorder, Major - classification - diagnosis - epidemiology - therapy
Diagnosis, Differential
Female
Health services needs and demand
Humans
Intelligence
Male
Mathematical Computing
Middle Aged
Neuropsychological Tests - statistics & numerical data
Norway
Prognosis
Psychometrics
Recurrence
Reference Values
Research Support, Non-U.S. Gov't
Sex Factors
Socioeconomic Factors
Abstract
Major depression is associated with impairment of cognitive functions, and especially higher-order cognitive processes referred to as executive functions (EF). Whether this is a general finding is unclear. Patients without EF impairment may have different treatment needs than patients with EF impairment, and will probably have a better everyday functioning. Thus, it is important to identify the prevalence and characteristics of depressed patients without EF impairment. Forty-three patients with recurrent major depressive disorder (19-51 years) and 50 healthy controls were included in the study. The subjects were assessed with neuropsychological tests selected to measure central areas of EF, and screened on clinical and demographic variables. Within the depressed group, a total of 56% were defined as EF unimpaired. These patients were characterised by higher intellectual abilities and fewer depression episodes than the subgroup of patients with EF impairment. The subgroups were similar in age at debut of illness, severity of depression, general psychopathology and global level of functioning. In conclusion, about half of patients with recurrent major depression have normal EF. Since cognitive impairment and depressive symptomatology seem to be distinct dimensions, a neuropsychological investigation could help to ensure optimal treatment in patients with recurrent major depression.
PubMed ID
16097404 View in PubMed
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Pathways to care for first-episode psychosis in an early detection healthcare sector: part of the Scandinavian TIPS study.

https://arctichealth.org/en/permalink/ahliterature70615
Source
Br J Psychiatry Suppl. 2005 Aug;48:s24-8
Publication Type
Article
Date
Aug-2005
Author
Jan Olav Johannessen
Tor K Larsen
Inge Joa
Ingrid Melle
Svein Friis
Stein Opjordsmoen
Bjørn Rishovd Rund
Erik Simonsen
Per Vaglum
Thomas H McGlashan
Author Affiliation
Division of Psychiatry, General Hospital of Rogaland, Armauer Hanssens vei 20, 4000 Stavanger, Norway. jojo@sir.no
Source
Br J Psychiatry Suppl. 2005 Aug;48:s24-8
Date
Aug-2005
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Critical Pathways - organization & administration
Delivery of Health Care - organization & administration - standards
Early Diagnosis
Female
Health Services Accessibility
Humans
Male
Middle Aged
Norway
Patient Acceptance of Health Care
Patient Care Team - organization & administration
Psychotic Disorders - diagnosis - therapy
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Abstract
BACKGROUND: Early detection programmes aim to reduce the duration of untreated psychosis (DUP) by public education and by prompt access to treatment via active outreach detection teams. AIMS: To determine whether those with first-episode psychosis in an early detection healthcare area with existing referral channels differ from those who access care via detection teams. METHOD: Those with first-episode psychosis recruited via detection teams were compared with those accessing treatment via conventional channels, at baseline and after 3 months of acute treatment. RESULTS: Patients recruited via detection teams are younger males with a longer DUP, a less dramatic symptom picture and better functioning; however they recover more slowly, and have more symptoms at 3-month follow-up. CONCLUSIONS: After establishing low threshold active case-seeking detection teams, we found clear differences between those patients entering treatment via detection teams v. those obtaining treatment via the usual channels. Such profiling may be informative for early detection service development.
PubMed ID
16055803 View in PubMed
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Validation of distinct amnesic and executive type memory deficit in a psychiatric sample based on retrieval performance.

https://arctichealth.org/en/permalink/ahliterature45717
Source
Scand J Psychol. 2005 Apr;46(2):201-8
Publication Type
Article
Date
Apr-2005
Author
Jens Egeland
Nils Inge Landrø
Kjetil Sundet
Arve Asbjørnsen
Anders Lund
Atle Roness
Bjørn Rishovd Rund
Author Affiliation
Department of Psychology, University of Oslo, Norway.
Source
Scand J Psychol. 2005 Apr;46(2):201-8
Date
Apr-2005
Language
English
Publication Type
Article
Keywords
Amnesia - diagnosis
Analysis of Variance
Comparative Study
Depression - psychology
Humans
Memory Disorders - diagnosis
Mental Recall
Neuropsychological Tests
Norway
Recognition (Psychology)
Research Support, Non-U.S. Gov't
Schizophrenic Psychology
Abstract
Studies of localized brain dysfunctions have revealed connections between patterns of cognitive dysfunction and specific profiles of memory impairment. The amnesic type of memory impairment is defined by deficits in both free recall and recognition memory, whereas the dysexecutive memory impairment is characterized by retrieval deficits, i.e. a disproportional impairment in free recall relative to recognition memory. The present study tests whether classifications of psychiatric patients into recall impaired only (= RO group) and Recall and Recognition impaired (= RR group) correspond to the executive type and amnesic type of memory impairment. The alternative hypothesis is that the two groups merely differ in degree of neuropsychological and psychiatric disturbance. Forty-four subjects impaired on California Verbal Learning Test (CVLT) were selected from a larger database of 103 impaired and non-impaired subjects with schizophrenia or recurrent major depression. Subjects were classified into RO and RR groups and compared on measures of memory strategy (recency effect and interference on CVLT), overall neuropsychological function (Stroop Test and WAIS-R similarity) and psychiatric symptom load (positive and negative symptoms). Repeated measures ANOVA showed no effects of group, i.e. the RR group did not perform consistently below the RO group with regard to memory strategy, neuropsychological function or psychiatric symptom load. Two out of three analyses showed group x test interaction, supporting the dissociation of distinct executive and amnesic profiles among psychiatric patients. The RO group was more susceptible to interference but had better recency score than the RR group. The RO had higher negative symptoms while the RR group had higher positive symptoms.
PubMed ID
15762947 View in PubMed
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