Skip header and navigation

Refine By

2 records – page 1 of 1.

Source
Nature. 2003 Sep 25;425(6956):338-9
Publication Type
Article
Date
Sep-25-2003
Author
Whitfield John
Source
Nature. 2003 Sep 25;425(6956):338-9
Date
Sep-25-2003
Language
English
Publication Type
Article
Keywords
Alaska
Animals
Ecosystem
Greenhouse Effect
Ice
Models, Theoretical
Oceans and Seas
Temperature
Trees
Notes
Comment In: Nature. 2003 Dec 11;426(6967):60214668834
PubMed ID
14508455 View in PubMed
Less detail

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

https://arctichealth.org/en/permalink/ahliterature90931
Source
Nat Genet. 2009 Jan;41(1):47-55
Publication Type
Article
Date
Jan-2009
Author
Aulchenko Yurii S
Ripatti Samuli
Lindqvist Ida
Boomsma Dorret
Heid Iris M
Pramstaller Peter P
Penninx Brenda W J H
Janssens A Cecile J W
Wilson James F
Spector Tim
Martin Nicholas G
Pedersen Nancy L
Kyvik Kirsten Ohm
Kaprio Jaakko
Hofman Albert
Freimer Nelson B
Jarvelin Marjo-Riitta
Gyllensten Ulf
Campbell Harry
Rudan Igor
Johansson Asa
Marroni Fabio
Hayward Caroline
Vitart Veronique
Jonasson Inger
Pattaro Cristian
Wright Alan
Hastie Nick
Pichler Irene
Hicks Andrew A
Falchi Mario
Willemsen Gonneke
Hottenga Jouke-Jan
de Geus Eco J C
Montgomery Grant W
Whitfield John
Magnusson Patrik
Saharinen Juha
Perola Markus
Silander Kaisa
Isaacs Aaron
Sijbrands Eric J G
Uitterlinden Andre G
Witteman Jacqueline C M
Oostra Ben A
Elliott Paul
Ruokonen Aimo
Sabatti Chiara
Gieger Christian
Meitinger Thomas
Kronenberg Florian
Döring Angela
Wichmann H-Erich
Smit Johannes H
McCarthy Mark I
van Duijn Cornelia M
Peltonen Leena
Author Affiliation
[1] Department of Epidemiology and Biostatistics, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands. [2] These authors contributed equally to this work.
Source
Nat Genet. 2009 Jan;41(1):47-55
Date
Jan-2009
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Body mass index
Cholesterol, HDL - blood
Cohort Studies
Coronary Disease - blood - genetics
European Continental Ancestry Group - genetics
Female
Genetic Predisposition to Disease
Genetic Screening
Genome, Human - genetics
Humans
Lipids - blood
Male
Metabolic Networks and Pathways - genetics
Middle Aged
Phenotype
Polymorphism, Single Nucleotide - genetics
Quantitative Trait Loci - genetics
Sex Characteristics
Abstract
Recent genome-wide association (GWA) studies of lipids have been conducted in samples ascertained for other phenotypes, particularly diabetes. Here we report the first GWA analysis of loci affecting total cholesterol (TC), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglycerides sampled randomly from 16 population-based cohorts and genotyped using mainly the Illumina HumanHap300-Duo platform. Our study included a total of 17,797-22,562 persons, aged 18-104 years and from geographic regions spanning from the Nordic countries to Southern Europe. We established 22 loci associated with serum lipid levels at a genome-wide significance level (P
Notes
Comment In: Nat Genet. 2009 Jan;41(1):5-619112455
PubMed ID
19060911 View in PubMed
Less detail