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[Assessment of the immunohematological status of children exposed to low doses of ionizing radiation in the early and late periods after the Chernobyl AES accident]

https://arctichealth.org/en/permalink/ahliterature37396
Source
Pediatriia. 1991;(12):16-20
Publication Type
Article
Date
1991
Author
V G Bebeshko
A A Chumak
E M Bruslova
V V Tal'ko
Zh N Minchenko
D A Bazyka
N M Tsvetkova
A G Bezpalenko
E N Dzhurinskaia
Source
Pediatriia. 1991;(12):16-20
Date
1991
Language
Russian
Publication Type
Article
Keywords
Accidents
Adolescent
Age Factors
Child
Child, Preschool
Comparative Study
English Abstract
Follow-Up Studies
Humans
Infant
Nuclear Reactors
Radiation Dosage
Radiation Injuries - blood - diagnosis - immunology
Time Factors
Ukraine
Abstract
The qualitative and quantitative parameters of hemopoiesis and immunocompetent cells were studied in 365 children in the early "iodine" and long-term periods after the accident. In accordance with primary response, a group consisting of 28 subjects with so-called "radiation injury" was distinguished. The early period was marked by unusual qualitative and quantitative hematological changes which, however, did not lead to the development of the hematological syndrome characteristic of acute radiation injury. Certain deviations that corresponded to somatic pathology were detectable at the late periods after the accident.
PubMed ID
1788014 View in PubMed
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[Clinico-immunocytological characteristics of leukemia in persons exposed to ionizing radiation effects due to the Chernobyl AES accident]

https://arctichealth.org/en/permalink/ahliterature24952
Source
Vestn Akad Med Nauk SSSR. 1991;(8):28-31
Publication Type
Article
Date
1991
Author
V G Bebeshko
V I Klimenko
A A Chumak
D A Bazyka
V V Tal'ko
Zh N Minchenko
E M Bruslova
S G Galkina
Source
Vestn Akad Med Nauk SSSR. 1991;(8):28-31
Date
1991
Language
Russian
Publication Type
Article
Keywords
Accidents
Adult
Comparative Study
English Abstract
Histocytochemistry
Humans
Leukemia, Lymphocytic, Acute - etiology
Leukemia, Myelocytic, Acute - etiology
Leukemia, Promyelocytic, Acute - etiology
Leukemia, Radiation-Induced - diagnosis - etiology - immunology
Male
Nuclear Reactors
Ukraine
Abstract
A total of 18 patients with acute leukemia from those exposed to radiation when they had liquidated the consequences of the accident at the Chernobyl Atomic Power Station were examined. Sixteen of them had acute myeloblast cell leukemia, one had acute lymphatic leukemia, and another one had acute promyelocytic leukemia. A complex of hematological, immunocytological, and cytochemical findings, as well as leukocytic and erythrocytic genetically determined antigen typing were used for diagnosis. Signs of severe vegetovascular dystonia was found to be followed by acute leukemia in all the patients. A relationship was established between the therapy resistance and the HLA antigen homozygosity in combination with genetically-determined low reactivity. There were no significant differences between the parameters in question and those in patients with acute leukemia who had been studied in the preaccident period.
PubMed ID
1950155 View in PubMed
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[Immunological aspects of the study of contingents of population exposed to ionizing radiation effects as the consequence of the Chernobyl AES accident]

https://arctichealth.org/en/permalink/ahliterature37324
Source
Vestn Akad Med Nauk SSSR. 1991;(8):16-20
Publication Type
Article
Date
1991
Author
A A Chumak
D A Bazyka
V V Tal'ko
Zh N Minchenko
A G Bezpalenko
N V Beliaeva
N K Gerasimenko
E A Dmitrenko
Iu L Konopleva
R A Nefedova
Source
Vestn Akad Med Nauk SSSR. 1991;(8):16-20
Date
1991
Language
Russian
Publication Type
Article
Keywords
Accidents
Blood Group Antigens - immunology
Child
Comparative Study
English Abstract
Enzymes - analysis
HLA Antigens - analysis
Humans
Immunity - radiation effects
Lymphocytes - immunology
Nuclear Reactors
Phenotype
Radiation, Ionizing
Rosette Formation
Ukraine
Abstract
The immune system was examined in those who participated in the liquidation of accident sequelae at the Chernobyl Atomic Power Station and the population exposed to ionizing radiation. Alteration in surface antigenic markers of basic regulatory subpopulations of immunocompetent cells and metabolic changes are caused by radiation and co-existent somatic diseases. Typing for HLA antigens and proteins with a genetically determined phenotype revealed characteristic features of their distribution for the general population.
PubMed ID
1950153 View in PubMed
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