Family medicine as a system of primary medical care delivery to man and his family can become under conditions of this country a mainstay of a successful realization of preventive strategies for chronic noninfectious diseases, and, in the first place, for ischemic heart disease. The article presents a project of a simplified scheme of actions for a family physician to carry on a prophylactic work among the population of his sector community. The stages the above scheme involves are as follows: assessment of an individual and general populational risk, dividing of the population into main groups of risk, implementation of measures designed to carry on a program of intervention intended for each group of the population with special reference to individual traits.
Overall fifty-five patients with myocardial infarction were examined. Activation of free radical oxidation of lipids and decrease in activity of enzymes of the antioxidant defence were especially pronounced in those patients with myocardial infarction presenting with acute left ventricular failure. Captopril administered by 6.25 mg daily increasing the dose to 37.5 mg a day over 2-3 days improves parameters characterizing central and cardiohemodynamics and has a beneficial effect on lipid peroxidation. Antioxidant effect of captopril is believed to be due to increase in enzymes of bodily antioxidant defense, such as glutathioneperoxidaze, glutathionereductaze, and elevation in blood levels of vitamin E and reduced glutathione.