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Are changes in left ventricular volume as measured with the biplane Simpson's method predominantly related to changes in its area or long axis in the prognostic evaluation of remodelling following a myocardial infarction?

https://arctichealth.org/en/permalink/ahliterature53776
Source
Eur J Echocardiogr. 2001 Jun;2(2):118-25
Publication Type
Article
Date
Jun-2001
Author
J E Otterstad
M. St John Sutton
G. Frøland
T. Skjaerpe
B. Graving
I. Holmes
Author Affiliation
Division of Cardiology, Vestfold Central Hospital, Toensberg, Norway.
Source
Eur J Echocardiogr. 2001 Jun;2(2):118-25
Date
Jun-2001
Language
English
Publication Type
Article
Keywords
Aged
Antihypertensive Agents - therapeutic use
Comparative Study
Echocardiography
Endpoint Determination
Female
Follow-Up Studies
Heart Ventricles - ultrasonography
Humans
Hypertension - complications - drug therapy
Male
Middle Aged
Myocardial Infarction - complications - physiopathology - ultrasonography
Norway - epidemiology
Predictive value of tests
Prognosis
Proportional Hazards Models
Research Support, Non-U.S. Gov't
Stroke Volume - physiology
Ventricular Remodeling - physiology
Abstract
AIMS: Two-dimensional (2D) echocardiography has been widely applied to measure left ventricular volumes with the biplane Simpson's method in the assessment of left ventricular remodelling following an acute myocardial infarction. This volume formula is based upon tracings of endocardium and measurement of long axis on left ventricular images. In the present follow-up study of post-myocardial infarction patients we evaluated the prognostic impact of changes in left ventricular areas and geometry versus long axis to determine if only long-axis measurements may be used for prognostic purposes. METHODS AND RESULTS: Two-dimensional echocardiographic video recordings of the apical four-chamber and long-axis views were obtained in 756 patients 2--7 days and 3 months following an acute myocardial infarction. All videotapes were sent to a core laboratory and left ventricular volumes were measured with the biplane Simpson's method in end-diastole and end-systole. During the first 3 months 44 patients had suffered one of the following end-points and were excluded: cardiac death, recurrent myocardial infarction, heart failure or chronic arrhythmia. Over a period of 3--24 months 58 such end-points occurred. With the Cox proportional hazards model the increase in left ventricular systolic volume was the strongest predictor for such events (Chi-square 18.5, P
PubMed ID
11882438 View in PubMed
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[Echocardiographic findings, pro-ANP and treatment in acute myocardial infarction without overt heart failure]

https://arctichealth.org/en/permalink/ahliterature54191
Source
Tidsskr Nor Laegeforen. 1999 Aug 20;119(19):2802-5
Publication Type
Article
Date
Aug-20-1999
Author
J E Otterstad
C. Hall
B. Graving
T. Skjaerpe
I. Holme
Author Affiliation
Medisinsk avdeling Vestfold sentralsykehus, Tønsberg.
Source
Tidsskr Nor Laegeforen. 1999 Aug 20;119(19):2802-5
Date
Aug-20-1999
Language
Norwegian
Publication Type
Article
Keywords
Aged
Atrial Natriuretic Factor - analysis
Controlled Clinical Trials
Echocardiography
English Abstract
Female
Heart Failure, Congestive - ultrasonography
Humans
Male
Middle Aged
Multicenter Studies
Myocardial Infarction - drug therapy - physiopathology - ultrasonography
Norway
Stroke Volume
Thrombolytic Therapy
Ventricular Function, Left
Ventricular Remodeling
Abstract
This study was undertaken to characterise patients without overt heart failure and with a left ventricular ejection fraction > or = 40% 2-7 days following an acute myocardial infarction. Patients with an ejection fraction > or = 40% (n = 868) had a lower prevalence of anterior myocardial infarction (p or = 40% had smaller left ventricular volume and mass (p or = 40%. Pro-ANP levels were not correlated with the ejection fraction or left ventricular volume. Approximately two thirds of the patients received thrombolytic treatment.
PubMed ID
10494198 View in PubMed
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Prognostic value of two-dimensional echocardiography and N-terminal proatrial natriuretic peptide following an acute myocardial infarction. Assessment of baseline values (2-7 days) and changes at 3 months in patients with a preserved systolic function.

https://arctichealth.org/en/permalink/ahliterature53709
Source
Eur Heart J. 2002 Jul;23(13):1011-20
Publication Type
Article
Date
Jul-2002
Author
J E Otterstad
M G St John Sutton
G S Froeland
I. Holme
T. Skjaerpe
C. Hall
Author Affiliation
Division of Cardiology, Vestfold Central Hospital, Toensberg, Norway.
Source
Eur Heart J. 2002 Jul;23(13):1011-20
Date
Jul-2002
Language
English
Publication Type
Article
Keywords
Aged
Atrial Natriuretic Factor - blood
Biological Markers - blood
Female
Humans
Male
Middle Aged
Myocardial Infarction - blood - mortality - ultrasonography
Norway
Prognosis
Proportional Hazards Models
Prospective Studies
Protein Precursors - blood
Research Support, Non-U.S. Gov't
Stroke Volume
Ventricular Dysfunction, Left - blood - ultrasonography
Ventricular Remodeling
Abstract
AIMS: The purpose of this prospective, observational study was to evaluate the relationship of left ventricular volumes, systolic function and plasma N-terminal proatrial natriuretic peptide (Nt-proANP) to cardiac morbidity and mortality in post-myocardial infarction patients with left ventricular ejection fraction > or =40%. METHODS AND RESULTS: Two-dimensional echocardiographic recordings and Nt-proANP measurements were obtained in 834 patients who survived acute myocardial infarction. Patients were examined at 2-7 days and 3 months after the index infarction and followed up for 24 months. All measurements of left ventricular volumes, ejection fraction and Nt-proANP were performed in core laboratories. During follow-up 102 patients sustained one or more incidents of the combined primary end-point: cardiac death (n=11), recurrent infarction (n=55) or heart failure requiring hospitalization or treatment with an ACE inhibitor and a diuretic (n=52). Using Cox proportional hazards model, baseline Nt-proANP predicted these events (chi-square 25.3, P or =40%) baseline Nt-proANP, but not echocardiographic left ventricular volumes predicted adverse cardiac events. Early changes in left ventricular volumes and ejection fraction from baseline to 3 months had a further prognostic impact on subsequent events (3-24 months).
Notes
Comment In: Eur Heart J. 2002 Jul;23(13):996-712093047
PubMed ID
12093053 View in PubMed
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Relationship between function and perfusion early after acute myocardial infarction.

https://arctichealth.org/en/permalink/ahliterature53729
Source
Int J Cardiovasc Imaging. 2001 Oct;17(5):383-93
Publication Type
Article
Date
Oct-2001
Author
M. Lombardi
J. Kvaerness
G. Torheim
J. Soma
F. Cellerini
M. Consalvo
M C Landini
C A Cecchi
C. Michelassi
T. Skjaerpe
R A Jones
P A Rinck
A. L'Abbate
Author Affiliation
CNR Clinical Physiology Institute, Pisa, Italy. lomass@ifc.cnr.it
Source
Int J Cardiovasc Imaging. 2001 Oct;17(5):383-93
Date
Oct-2001
Language
English
Publication Type
Article
Keywords
Adrenergic beta-Agonists - diagnostic use
Adult
Aged
Comparative Study
Contrast Media
Coronary Angiography
Dobutamine - diagnostic use
Echocardiography
Female
Gadolinium DTPA - diagnostic use
Humans
Italy - epidemiology
Magnetic Resonance Imaging, Cine
Male
Middle Aged
Myocardial Contraction - physiology
Myocardial Infarction - diagnosis - physiopathology - surgery
Myocardial Reperfusion
Norway - epidemiology
Observer Variation
Research Support, Non-U.S. Gov't
Statistics
Time Factors
Treatment Outcome
Ventricular Function, Left - physiology
Abstract
To assess the relationship between baseline left ventricle function, functional reserve and resting myocardial perfusion in patients with acute myocardial infarction (AMI). After AMI the presence of dysfunctioning but viable myocardium plays a determinant role in clinical outcome. Regional ventricular function was evaluated by echocardiography both in resting conditions and during dobutamine infusion (10 microg/kg/min). Perfusion was assessed by magnetic resonance imaging in a single slice approach where the first pass of an intravenously injected bolus of gadolinium-based contrast agent was followed through six regions of interest within the myocardium. In each patient a region with normal function was used as reference and the cross-correlation coefficient (CCC), which described the myocardial perfusion relatively to the reference region (CCC = 1 means equivalent perfusion), was obtained for the other five myocardial regions. Twenty-two patients were enrolled into the study. Sixty-one segments had normal function and normal perfusion (CCC = 0.92+/-0.23). The perfusion deficit was more marked in the 29 regions with resting akinesia-dyskinesia than in the 20 hypokinetic regions (CCC = 0.71+/-0.45 vs. 0.84+/-0.23; p
PubMed ID
12025952 View in PubMed
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Source
Tidsskr Nor Laegeforen. 2001 Jan 20;121(2):173-6
Publication Type
Article
Date
Jan-20-2001
Author
E. Rødevand
J F Skomsvoll
M. Wallenius
A Z Henriksen
T. Skjaerpe
A B Tafjord
Author Affiliation
Revmatologisk avdeling, Regionsykehuset i Trondheim 7006 Trondheim. erodevan@online.no
Source
Tidsskr Nor Laegeforen. 2001 Jan 20;121(2):173-6
Date
Jan-20-2001
Language
Norwegian
Publication Type
Article
Keywords
Adult
Aortography
Cohort Studies
Female
Glucocorticoids - administration & dosage
Humans
Incidence
Male
Middle Aged
Norway - epidemiology
Prednisolone - administration & dosage
Prognosis
Retrospective Studies
Takayasu Arteritis - diagnosis - drug therapy - epidemiology - radiography
Abstract
Takayasu's arteritis is a chronic, idiopathic, inflammatory disease that affects aorta and its main branches. The disease is rare; its etiology is unknown and shows race differences. The inflammation of the arteries may lead to stenosis, occlusions, dilatations or aneurysms. The clinical picture and angiographic findings are not previously reported in a Norwegian cohort.
We report a retrospective, hospital-based study describing the clinical picture, diagnostic findings, treatment and prognosis in a cohort of six patients in Central Norway with Takayasu's arteritis. The data was extracted through chart review.
In the period 1988-2000, six patients with Takayasu's arteritis, five women and one man, were identified. All the patients were of Norwegian origin. Median age at diagnosis was 39 years, range 24-63 years, and median time from first symptoms to definite diagnosis was six months, range 1-36 months. The estimated minimum annual incidence was 0.8 per million. All patients had elevated erythrocyte sedimentation rate; five out of six patients had unilateral or bilateral subclavian stenosis; one patient had a thoracoabdominal aneurysm. All patients were treated with prednisolone. There were no deaths in the observation period of median 7.5 years, range 0-26 years.
Takayasu's arteritis is a rare disease in our region, with lower incidence than reported in the literature. The prognosis is excellent, but the morbidity was substantial. The clinical findings are similar to those reported in other studies. The location and appearance of the angiographic findings were characteristic for the disease.
PubMed ID
11475193 View in PubMed
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