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[Changes of fatty acid spectrum of thrombocyte lipids in patients with a stable and unstable angina]

https://arctichealth.org/en/permalink/ahliterature97039
Source
Lik Sprava. 2009 Oct-Dec;(7-8):30-2
Publication Type
Article
Author
V H Lyzohub
T V Zaval's'ka
Kh A Kh Abu Sara
T S Briuzhina
O V Savchenko
Source
Lik Sprava. 2009 Oct-Dec;(7-8):30-2
Language
Ukrainian
Publication Type
Article
Keywords
Adult
Aged
Angina Pectoris - blood - metabolism
Angina, Unstable - blood - metabolism
Blood Platelets - metabolism
Case-Control Studies
Fatty Acids - metabolism
Humans
Middle Aged
Phospholipids - metabolism
Abstract
Ischemic heart desease (IHD) remains actual issue of the current clinical medicine, because, IHD takes a leading position among reasons of death rate of population. Purpose of the study was to find diagnostic features of fat-acid composition of lipid of thrombocytes in patients with stable and unstable course of ischemic heart disease (IHD). 52 patients with an unstable angina pectoris aged 42-65 years and 31 patients with stable angina aged 41-66 years have been observed. Reliable changes in relation of the sum of saturated, unsaturated and poli-unsaturated of fat acids of phosphotides of thrombocytes in patients with unstable course of ischemic heart disease (IHD) have been detected. It improves knowledge about the mechanisms of destabilization of coronal circulation of blood.
PubMed ID
20455444 View in PubMed
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[Lipid complex in subpalatine tonsils in normal state and pathology]

https://arctichealth.org/en/permalink/ahliterature30762
Source
Fiziol Zh. 2003;49(2):111-3
Publication Type
Article
Date
2003
Author
Iu V Mitin
Iu V Shevchuk
T S Briuzhina
Author Affiliation
National Medical University, Kiev.
Source
Fiziol Zh. 2003;49(2):111-3
Date
2003
Language
Ukrainian
Publication Type
Article
Keywords
Adolescent
Adult
Arachidonic Acid - analysis - biosynthesis
Child
Chromatography, Gas
Chronic Disease
Comparative Study
English Abstract
Fatty Acids - metabolism
Humans
Hypertrophy
Lipid Peroxidation
Lipids - analysis
Male
Tonsil - pathology - physiology
Abstract
A fat-acid compound of lipids in the subpalatine tonsils was studied by gas chromatography in normal state, chronic tonsillitis and hypertrophy of tonsils. We have determined that in saturation of the lipid complex raised in the subpalatine tonsils due to an increase in the level of arachidonic acid. It gives evidence for an activation of the lipid peroxidation leading to a pathological process.
PubMed ID
12945125 View in PubMed
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[Structural and functional changes to the lungs and the lipid metabolic status in cardiogenic shock]

https://arctichealth.org/en/permalink/ahliterature54130
Source
Fiziol Zh. 1999;45(6):81-7
Publication Type
Article
Date
1999
Author
S H Hychka
T S Briuzhina
O O Moibenko
Author Affiliation
Medical Institute, Ukrainian Association of Folk Medicine, Kiev.
Source
Fiziol Zh. 1999;45(6):81-7
Date
1999
Language
Ukrainian
Publication Type
Article
Keywords
Autopsy
Breath Tests
Chromatography, Gas
English Abstract
Humans
Lipid Metabolism
Lipids - analysis
Lung - chemistry - metabolism - pathology - physiopathology
Microscopy, Electron
Shock, Cardiogenic - metabolism - pathology - physiopathology
Abstract
The functional and structural manifestations of lipid metabolism disorders in the lungs were studied in comparison with the changes of fatty acid composition of lipids of pulmonary tissue, venous and arterial blood, expirated air condensate and sweat during the development of cardiogenic shock in patients with myocardial infarction. It has been established that the lungs accumulate neutral lipids and lose phospholipids and polyunsaturated fatty acids. These changes are combined with intracellular lesion of osmiophilic lamellated corpuscles and disturbance of their excretion into alveolar cavities. At the same time the increase of polyunsaturated fatty acids content in expirated air condensate and sweat of patients is noted can be related to the elimination of the excess of these substrates from intercellular space.
PubMed ID
10687087 View in PubMed
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[The effect of alpha-adrenoblockaders on the lipid complex of the myocardium, liver and erythrocytes in dogs with pulmonary heart failure]

https://arctichealth.org/en/permalink/ahliterature54738
Source
Fiziol Zh. 1995 Sep-Dec;41(5-6):80-3
Publication Type
Article
Author
S B Frantsuzova
L L Arshinnikova
T S Briuzhina
E Ia Kravchenko
Source
Fiziol Zh. 1995 Sep-Dec;41(5-6):80-3
Language
Ukrainian
Publication Type
Article
Keywords
Adrenergic alpha-Antagonists - pharmacology - therapeutic use
Animals
Comparative Study
Dogs
Drug Evaluation, Preclinical
English Abstract
Erythrocytes - drug effects - metabolism
Fatty Acids - metabolism
Female
Heart - drug effects
Lipid Metabolism
Liver - drug effects - metabolism
Male
Myocardium - metabolism
Prazosin - pharmacology - therapeutic use
Pulmonary Heart Disease - drug therapy - metabolism
Tropanes - pharmacology - therapeutic use
Abstract
Fatty acid spectrum of phospholipids and free cholesterol level in the myocardium, liver and erythrocytes were studied in dogs with the experimental lung-heart insufficiency (LHI). The content of polyunsaturated fatty acids of phospholipids in erythrocytes from peripheric blood and in free cholesterol level (2-3 times) in myocardium, liver and erythrocytes of dogs under investigated conditions decreased. It is shown that pharmacotherapy with alpha-adrenoblockers (thropaphen and prasozin) has led to the normalization of disturbances of the erythrocytic lipid complex and had caused inhibition of peroxidase reactions in the myocardium and liver of the dogs with LHI.
PubMed ID
9026398 View in PubMed
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