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Late infantile metachromatic leucodystrophy. Report of 2 cases and review of in vivo diagnostic tests.

https://arctichealth.org/en/permalink/ahliterature43589
Source
Beitr Pathol. 1972 Jul;146(4):322-31
Publication Type
Article
Date
Jul-1972

Risk of cervical intraepithelial neoplasia in women with glomerulonephritis.

https://arctichealth.org/en/permalink/ahliterature24892
Source
BMJ. 1991 Feb 16;302(6773):375-7
Publication Type
Article
Date
Feb-16-1991
Author
F. Hartveit
B. Bertelsen
S. Thunold
B O Maehle
E. Skaarland
J. Christensen
Author Affiliation
Department of Pathology, Gade Institute, University of Bergen, Norway.
Source
BMJ. 1991 Feb 16;302(6773):375-7
Date
Feb-16-1991
Language
English
Publication Type
Article
Keywords
Adult
Aged
Carcinoma in Situ - etiology
Comparative Study
DNA, Viral - analysis
Female
Glomerulonephritis - complications - drug therapy
Humans
Immunosuppressive Agents - therapeutic use
Middle Aged
Papillomavirus - isolation & purification
Research Support, Non-U.S. Gov't
Retrospective Studies
Risk factors
Tumor Virus Infections - complications
Uterine Cervical Dysplasia - etiology
Uterine Cervical Neoplasms - etiology - microbiology
Abstract
OBJECTIVE--To investigate the occurrence of cervical intraepithelial neoplasia in women with glomerulonephritis and its possible association with immunosuppressive treatment. DESIGN--Retrospective study of cytological or histological specimens from women presenting with glomerulonephritis and a group of case and age matched controls. SETTING--University department of pathology, Norway. PATIENTS--81 women presenting with glomerulonephritis from 1981 to 1988, from whom gynaecological cytological or histological specimens were available. A group of 162 case and age matched controls. MAIN OUTCOME MEASURES--Age when glomerulonephritis of cervical intraepithelial neoplasia was diagnosed, type and characteristics of kidney lesion, stage of cervical intraepithelial neoplasia and presence of human papillomavirus, use of immunosuppressive treatment. RESULTS--Cervical intraepithelial neoplasia was more common in women with glomerulonephritis than in their controls (16/81 (20%) v 7/162 (4%), p less than 0.001) and was more advanced in those with glomerulonephritis than in the controls (9/81 (11%) of the study group had grade III cervical intraepithelial neoplasia compared with 1/162 (1%) of the controls). The increased occurrence of cervical lesions was independent of the use of immunosuppressive treatment, but the individual lesions tended to be more advanced when it was used (four of the seven cervical lesions in women with glomerulonephritis who had received immunosuppressive treatment were carcinoma in situ). Of the nine cervical lesions tested, seven were virus associated. CONCLUSION--Women with glomerulonephritis should have regular cervical smears, irrespective of their use of immunosuppressive treatment.
PubMed ID
1848453 View in PubMed
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