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Source
Ugeskr Laeger. 1989 Mar 20;151(12):753-5
Publication Type
Article
Date
Mar-20-1989
Author
P H Pedersen
U G Svendsen
Source
Ugeskr Laeger. 1989 Mar 20;151(12):753-5
Date
Mar-20-1989
Language
Danish
Publication Type
Article
Keywords
Aerosols - supply & distribution
Chlorofluorocarbons, Methane - supply & distribution
Denmark
English Abstract
Abstract
In 1987, approximately 1.18 million aerosol dispensers for medicinal use were sold in Denmark. These contained approximately 29 tons of completely halogenized CFC gases ("Freon") and the preparations were employed for the treatment of bronchial asthma and rhinitis. The possibilities of substitutes are discussed in this article. Preparations are already available which do not contain CFC. Producers of CFC are also attempting to develop new aerosol gases which do not damage the environment. Perhaps these will be found in medicinal preparations in the future.
PubMed ID
2711484 View in PubMed
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Gamma knife surgery of meningiomas involving the cavernous sinus: long-term follow-up of 100 patients.

https://arctichealth.org/en/permalink/ahliterature97633
Source
Neurosurgery. 2010 Apr;66(4):661-8; discussion 668-9
Publication Type
Article
Date
Apr-2010
Author
Bente Sandvei Skeie
P O Enger
G O Skeie
F. Thorsen
P-H Pedersen
Author Affiliation
Department of Neurosurgery, Haukeland University Hospital, N-5021 Bergen, Norway. bsai@helse-bergen.no
Source
Neurosurgery. 2010 Apr;66(4):661-8; discussion 668-9
Date
Apr-2010
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Cavernous Sinus - surgery
Female
Humans
Longitudinal Studies
Male
Meningeal Neoplasms - pathology - surgery
Meningioma - pathology - surgery
Middle Aged
Radiosurgery - methods
Retrospective Studies
Time Factors
Treatment Outcome
Young Adult
Abstract
OBJECTIVE: Resection of meningiomas involving the cavernous sinus often is incomplete and associated with considerable morbidity. As a result, an increasing number of patients with such tumors have been treated with gamma knife surgery (GKS). However, few studies have investigated the long-term outcome for this group of patients. METHODS: 100 patients (23 male/77 female) with meningiomas involving the cavernous sinus received GKS at the Department of Neurosurgery at Haukeland University Hospital, Bergen, Norway, between November 1988 and July 2006. They were followed for a mean of 82.0 (range, 0-243) months. Only 2 patients were lost to long-term follow-up. Sixty patients underwent craniotomy before radiosurgery, whereas radiosurgery was the primary treatment for 40 patients. RESULTS: Tumor growth control was achieved in 84.0% of patients. Twelve patients required re-treatment: craniotomy (7), radiosurgery (1), or both (4). Three out of 5 patients with repeated radiosurgery demonstrated secondary tumor growth control. Excluding atypical meningiomas, the growth control rate was 90.4%. The 1-, 5-, and 10-year actuarial tumor growth control rates are 98.9%, 94.2%, and 91.6%, respectively. Treatment failure was preceded by clinical symptoms in 14 of 15 patients. Most tumor growths appeared within 2.5 years. Only one third grew later (range, 6-20 yr). The complication rate was 6.0%: optic neuropathy (2), pituitary dysfunction (3), worsening of diplopia (1), and radiation edema (1). Mortality was 0. At last follow-up, 88.0% were able to live independent lives. CONCLUSION: GKS gives long-term growth control and has a low complication rate. Most tumor growths manifest within 3 years following treatment. However, some appear late, emphasizing the need for long-term follow-up.
PubMed ID
20305491 View in PubMed
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[Patients with early stages of endometrial cancer should be spared adjuvant radiotherapy. Danish Endometrial Cancer Group]

https://arctichealth.org/en/permalink/ahliterature22066
Source
Ugeskr Laeger. 1997 May 26;159(22):3403-7
Publication Type
Article
Date
May-26-1997
Author
H K Poulsen
M. Jacobsen
K. Bertelsen
J E Andersen
S. Ahrons
J E Bock
E. Bostofte
S A Engelholm
B. Hølund
A K Jakobsen
H. Kiaer
M H Nyland
P H Pedersen
I S Christophersen
Author Affiliation
Odense Universitetshospital, Den danske endometriecancergruppe (DEMCA).
Source
Ugeskr Laeger. 1997 May 26;159(22):3403-7
Date
May-26-1997
Language
Danish
Publication Type
Article
Keywords
Adult
Aged
Carcinoma - pathology - radiotherapy - surgery
Denmark
Endometrial Neoplasms - pathology - radiotherapy - surgery
English Abstract
Female
Follow-Up Studies
Humans
Hysterectomy
Middle Aged
Neoplasm Recurrence, Local
Neoplasm Staging
Radiotherapy, Adjuvant
Research Support, Non-U.S. Gov't
Risk factors
Abstract
In an attempt to create uniform nationwide guidelines for the management of all stages of endometrial carcinoma, and to limit the use of adjuvant radiation therapy in stage I disease to high-risk patients only, a protocol was developed by the Danish Endometrial Cancer group (DEMCA). From September 1986 through August 1988, 1214 women in Denmark with newly diagnosed carcinoma of the endometrium have been treated according to this protocol. This figure represents all endometrial carcinomas diagnosed in Denmark during this two-year period. The primary treatment was total abdominal hysterectomy and bilateral salpingo-oophorectomy, no preoperative radiation therapy was delivered. In 1039 cases no macroscopic residual tumour and/or microscopic tumor tissue in the resection margins was found following surgery. Based on surgery and histopathology, these patients were classified as: P-stage I low risk (n = 641), P-stage I high risk (n = 235), P-stage II (n = 105) and P-stage III, Group 1 (n = 58). No postoperative radiation therapy was given to P-I low risk cases. P-I high risk, P-II, and P-III (Group 1) cases received external radiation therapy. Recurrence rate at 68-92 months follow-up was 45/641 (7%) in P-I low risk, 36/235 (15%) in P-I high risk, 30/105 (29%) in P-II, and 27/58 (47%) in P-III (Group 1) cases. Fifteen of 17 vaginal recurrences in P-I low risk cases were salvaged (mean observation time 61 months). In this population-based investigation it has been shown that P-stage low-risk patients are adequately treated by total abdominal hysterectomy and bilateral salpingo-oophorectomy, and that no pre- or postoperative radiation therapy is necessary.
PubMed ID
9199028 View in PubMed
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