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Identification as a Mutation Carrier and Effects on Life According to Experiences of Finnish Male BRCA1/2 Mutation Carriers.

https://arctichealth.org/en/permalink/ahliterature303047
Source
J Genet Couns. 2018 08; 27(4):874-884
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
08-2018
Author
Outi Kajula
Outi Kuismin
Helvi Kyngäs
Author Affiliation
Research Unit of Nursing Science and Health Management, Faculty of Medicine, University of Oulu, P.O. Box 5000, 90014, Oulu, Finland. outi.kajula@oulu.fi.
Source
J Genet Couns. 2018 08; 27(4):874-884
Date
08-2018
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Adult
BRCA2 Protein - genetics
Breast Neoplasms, Male - genetics - prevention & control
Finland
Genetic Counseling - psychology
Genetic Testing - methods
Humans
Life Style
Male
Men's health
Middle Aged
Mutation
Abstract
Earlier studies have explored post-identification experiences of male BRCA1/2 mutation carriers, but more detailed knowledge of both their experiences and effects of identification as a carrier on their lives is required to improve genetic counseling. Thus, the aim of this study was to acquire deeper and broader insights into their experiences. Qualitative data were collected from theme-based interviews with 31 men carrying BRCA1/2 mutations in Finland, and analyzed using inductive content analysis. Three categories of the participants' responses to identification as BRCA1/2 mutation carriers were identified (personal, offspring-related and related to other relatives), mainly concerning issues associated with cancer, hereditary transmission of their mutations, and life decisions. Although there were many neutral responses regarding the issues, there were also strong emotional reactions and cancer worries. Identification as a carrier also had several effects on participants' lifestyles, including adoption of healthier and disease-preventing behavior, and social well-being, such as family planning and attitudes to life. The results provide detailed information about several aspects of male BRCA1/2 mutation carriers' experiences, which could be used to develop a tentative model of tailored genetic counseling for them.
PubMed ID
29332197 View in PubMed
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The Quality of Genetic Counseling and Connected Factors as Evaluated by Male BRCA1/2 Mutation Carriers in Finland.

https://arctichealth.org/en/permalink/ahliterature287432
Source
J Genet Couns. 2016 Jun;25(3):413-21
Publication Type
Article
Date
Jun-2016
Author
Outi Kajula
Maria Kääriäinen
Jukka S Moilanen
Helvi Kyngäs
Source
J Genet Couns. 2016 Jun;25(3):413-21
Date
Jun-2016
Language
English
Publication Type
Article
Keywords
Adult
Breast Neoplasms, Male - genetics
Finland
Genes, BRCA1
Genes, BRCA2
Genetic Counseling
Genetic Predisposition to Disease
Heterozygote
Humans
Male
Mutation
Quality of Life
Abstract
There is little written about the quality of genetic counseling for men with the BRCA1/2 mutation. The purpose of this study was to describe the quality of genetic counseling and connected factors according to Finnish male BRCA1/2 mutation carriers' (n?=?35) perspectives and reasons for seeking genetic counseling. Data were collected from the Departments of Clinical Genetics at five Finnish university hospitals. The exploratory study design was conducted using a 51-item questionnaire based on a previously devised quality of counseling model and analyzed using non-parametric tests and principle content analysis. The satisfaction level with genetic counseling was high, especially with regard to the content of genetic counseling. The benefit of genetic counseling on the quality of life differed significantly (p?
Notes
Cites: Br J Cancer. 2002 Aug 27;87(5):502-812189544
Cites: J Clin Nurs. 2013 Oct;22(19-20):2704-1323551345
Cites: J Genet Couns. 2010 Aug;19(4):360-7020306122
Cites: J Genet Couns. 2006 Apr;15(2):77-8316761103
Cites: Res Nurs Health. 2006 Oct;29(5):489-9716977646
Cites: Ann Oncol. 2003 Apr;14(4):549-5312649099
Cites: Scand J Caring Sci. 2010 Sep;24(3):548-5620409053
Cites: J Genet Couns. 2005 Jun;14(3):207-1715959652
Cites: Fam Cancer. 2006;5(1):61-7516528610
Cites: Sociol Health Illn. 2006 Nov;28(7):969-8817163862
Cites: Am J Hum Genet. 2000 Dec;67(6):1494-50411063672
Cites: Science. 1994 Oct 7;266(5182):66-717545954
Cites: Musculoskeletal Care. 2011 Mar;9(1):19-2421351366
Cites: Nature. 1995 Dec 21-28;378(6559):789-928524414
Cites: Eur J Cancer Care (Engl). 2011 Mar;20(2):204-1120597958
Cites: Br J Cancer. 2007 Jan 15;96(1):11-517213823
Cites: J Genet Couns. 2007 Apr;16(2):211-2217279329
Cites: Fam Cancer. 2009;8(3):221-919165626
Cites: Psychooncology. 2013 Feb;22(2):417-2522135240
Cites: Eur J Hum Genet. 2001 Jul;9(7):492-50011464240
Cites: Psychol Health. 2011 Jul;26(7):855-7321432729
Cites: Fam Cancer. 2011 Sep;10(3):597-60321603983
PubMed ID
26416184 View in PubMed
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