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Atopic manifestations are more common in patients with Crohn disease than in the general population.

https://arctichealth.org/en/permalink/ahliterature15126
Source
Scand J Gastroenterol. 2004 Aug;39(8):731-6
Publication Type
Article
Date
Aug-2004
Author
P. Myrelid
M. Dufmats
I. Lilja
C. Grinn
O. Lannerstad
R. Sjödahl
Author Affiliation
Dept. of Surgery, Unit of Colorectal Surgery, University Hospital, Linkoping, Sweden. par.myrelid@lio.se
Source
Scand J Gastroenterol. 2004 Aug;39(8):731-6
Date
Aug-2004
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Asthma - complications
Crohn Disease - complications - immunology
Eczema - complications
Female
Humans
Hypersensitivity, Immediate - complications
Male
Middle Aged
Rhinitis, Allergic, Perennial - complications
Rhinitis, Allergic, Seasonal - complications
Abstract
BACKGROUND: The role of TNF-alpha in Crohn disease is now well established and anti-TNF-alpha is frequently used as a second- or third-line treatment. Tumor necrosis factor-alpha (TNF-alpha) is traditionally associated with macrophages but has recently also been found in mast cells of the ileal wall in patients with Crohn disease. As it is well known that mast cells and TNF-alpha play important roles in atopic manifestations like asthma, allergic rhinitis; and eczema the aim of this study was to investigate whether these are seen more commonly in Crohn patients than in the general population. METHODS: Patients with Crohn disease (n = 308), aged 18-50 years, living in the Linköping region in southeast Sweden, were asked to answer a questionnaire regarding the presence of any kind of atopic manifestations. The questionnaire was also sent to 930 controls collected from the Southeastern Region Population Registry. The controls were matched according to age, sex, and place of residence. RESULTS: The response rate among the Crohn patients was 91% (280/308) and among controls 84% (779/930). Eczema was a significantly more frequent manifestation, being almost twice as common in Crohn patients (27%) as in the general population (16%). Adjustment by logistic regression for place of residence, gender, age and coexistence of any other atopic manifestation did not change the odds ratios significantly. CONCLUSION: Atopic manifestations as a group, and eczema as a single manifestation, are significantly more frequent in Crohn patients than in the general population.
PubMed ID
15513357 View in PubMed
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Effects of a health screening on mortality and causes of death in middle-aged men. A prospective study from 1970 to 1974 of mean in Malmö, born 1914.

https://arctichealth.org/en/permalink/ahliterature68138
Source
Scand J Soc Med. 1977;5(3):137-40
Publication Type
Article
Date
1977
Author
O. Lannerstad
N H Sternby
S O Isacsson
G. Lindgren
S E Lindell
Source
Scand J Soc Med. 1977;5(3):137-40
Date
1977
Language
English
Publication Type
Article
Keywords
Cardiovascular Diseases - mortality
Humans
Male
Mass Screening
Middle Aged
Mortality
Prospective Studies
Risk
Sweden
Abstract
All men born in even-numbered months in 1914 and domiciled in Malmö were invited in 1969 to participate in an investigation regarding risk factors for cardiovascular disease. Individuals with a blood pressure of 165/110 and over were treated and a sub-sample of heavy smokers were later invited to take part in a quit-smoking project. During the following five year period total and cause-specific mortality in the examined group was compared with corresponding data for men born in uneven months in 1914. Mortality in the examined cohort was lower than among controls and differed significantly from that in the control group with regard to cardiovascular mortality.
PubMed ID
594708 View in PubMed
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Morbidity related to smoking and other risk factors. A population study of disability pension, hospital care and sickness benefit days among middle-aged men in Malmö, Sweden.

https://arctichealth.org/en/permalink/ahliterature68098
Source
Scand J Soc Med. 1980;8(1):25-31
Publication Type
Article
Date
1980
Author
O. Lannerstad
Source
Scand J Soc Med. 1980;8(1):25-31
Date
1980
Language
English
Publication Type
Article
Keywords
Cardiovascular Diseases - epidemiology
Disability Evaluation
Follow-Up Studies
Hospitalization - utilization
Humans
Insurance, Health
Lung Diseases - epidemiology
Male
Middle Aged
Pensions - utilization
Risk
Smoking - complications
Sweden
Abstract
In 1969 a cohort of 703 men born in 1914 was screened to determine the prevalence of cardivascular and pulmonary diseases among middle-aged men. Smoking habits and other cardiovascular risk factors were registered. Hypertension was treated. The disability pension rate among non-smokers was considerably lower than that for smokers. Also the proportion of individuals who had been admitted to hospital and the proportion of individuals who had reported sick was lower in non-smokers than in smokers. The ex-smokers showed an intermediate position both in terms of disability pension rate and in proportion of individuals admitted to hospital. High systolic blood pressure, high cholesterol level and high triglyceride values in 1969 were not associated with increased disability pension rate, hospitalization rate or with increased sick leave.
PubMed ID
7375875 View in PubMed
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Risk factors for premature death in men 56--60 years old. A prospective study of men born 1914, living in Malmö, Sweden.

https://arctichealth.org/en/permalink/ahliterature27489
Source
Scand J Soc Med. 1979;7(1):41-7
Publication Type
Article
Date
1979
Author
O. Lannerstad
S O Isacsson
S E Lindell
Source
Scand J Soc Med. 1979;7(1):41-7
Date
1979
Language
English
Publication Type
Article
Keywords
Accidents
Cardiovascular Diseases - mortality
Cerebrovascular Disorders - mortality
Cholesterol - blood
Follow-Up Studies
Humans
Male
Middle Aged
Mortality
Neoplasms - mortality
Prospective Studies
Risk
Smoking - mortality
Suicide
Sweden
Triglycerides - blood
Abstract
In a five-year follow-up of a random sample of men aged 55 the association between risk factors and premature death was analysed. The overall mortality in five years was 5.8%. The mortality among the smokers was 8%; among non-smokers 2%. Of 16 cancer deaths all were smokers except one who was an ex-smoker. In spite of treatment of hypertension (greater than 165/110 mmHg) there was an association between high blood pressure and premature death, particularly when cause of death was cardiovascular disease. There was no association between premature death and serum cholesterol, serum triglycerides or physical activity. The study is based on 703 men, of whom 41 died. The autopsy frequency was 93%. Only 3 men (0.4%) were lost to follow-up.
PubMed ID
432566 View in PubMed
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