A study of 45 patients with chronic obstructive bronchitis by the method of radionuclide ventriculography with 99mTc showed that even the early stages of the disease were characterized by an inhibition of the contractile function of the left cardiac ventricle. With progression of respiratory insufficiency, maintaining of the left cardiac ventricle stroke volume is achieved by increase of the final-diastolic and final-systolic volumes. Appearance of signs of cardiac decompensation is accompanied by a breakdown of this compensatory mechanism accompanied by a reduction of the strike volume and diminished rate of contraction of the circular fibers of the left ventricle myocardium.
Left and right ventricular function was evaluated by means of radionuclide ventriculography in 44 patients with paroxysms of supraventricular tachycardia without sings of circulatory insufficiency of coronaro- and noncoronarogenic origin. Depending on the efficacy of antiarrhythmic treatment the patients were subdivided in two groups: patients amenable to treatment and patients with refractory arrhythmia. It was established that radionuclide ventriculography allows to objectively evaluate the functional state of both ventricles and to reveal early signs of deterioration of the hemodynamic productivity of the heart in patients with paroxysms of supraventricular tachycardia. Reduction of the pumping function of the right ventricle in patients with refractory tachycardia along with hyperkinesia of its separate segments, changes of left ventricular rate and an increase of the terminal diastolic and systolic volumes of both ventricles without changes of the stroke volume may be a criterion of refractoriness of arrhythmia in this category of patients.
Radionuclide ventriculography was used to evaluate the functional structural parameters of the right ventricle systole and diastole in 100 patients with paroxysmal tachyarrhythmia without signs of cardiac insufficiency (42 with cardiac fibrillation, 35--supraventricular tachycardia, 23--with ventricular arrhythmia). Results indicate that radionuclide ventriculography allows to evaluate objectively the functional state of the right ventricle in patients with paroxysmal tachycardia, detect early signs of deterioration of its hemodynamic productivity and contractile capacity in patients refractory to treatment of cardiac arrhythmias.