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MOLECULAR EPIDEMIOLOGY OF TREPONEMA PALLIDUM IN BORDER REGION OF RUSSIAN FEDERATION (TUVA REPUBLIC).

https://arctichealth.org/en/permalink/ahliterature297773
Source
Mol Gen Mikrobiol Virusol. 2017; 35(1):26-30
Publication Type
Journal Article
Author
A A Kubanov
D V Vorob'ev
A P Obukhov
O A Obraztsova
D G Deryabin
Source
Mol Gen Mikrobiol Virusol. 2017; 35(1):26-30
Language
English
Russian
Publication Type
Journal Article
Keywords
Adult
Female
Genotype
Humans
Male
Molecular Epidemiology
Phylogeny
Siberia
Syphilis - epidemiology - genetics
Treponema pallidum - genetics
Abstract
The 111 strains of T. pallidum subsp. pallidum collected in Tuva Republic in 2013-2016 were typed by the arp, tpr (E, G, J) and tp0548 genes. The 7 subtypes were identified, in which the 14 d/f type was predominant (90.1%). The minor subtypes 14 b/f, 14 c/f, 14 d/g and 14 i/f constituted 0.9-1.8%. Single strains of 4 d/f H 9 d/f types (each 0.9%) previously described in China were detected in 2015. Both 9 and 14 arp gene variants were found in 3 clinical specimens for the first time in 2015-2016. Similarities in the molecular epidemiology of syphilis in Tuva Republic and Russia were demonstrated as well as differences from the T. pallidum subsp. pallidum population in China and Western Europe.
PubMed ID
30561941 View in PubMed
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