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12 records – page 1 of 2.

Aetiology of posterior uveitis in a tertiary centre in Finland.

https://arctichealth.org/en/permalink/ahliterature309391
Source
Acta Ophthalmol. 2020 Feb; 98(1):e135-e136
Publication Type
Letter
Date
Feb-2020

Early glycaemic control for maintaining visual function in type 1 diabetes: The Oulu cohort study of diabetic retinopathy.

https://arctichealth.org/en/permalink/ahliterature290645
Source
Eur J Ophthalmol. 2018 Mar 01; :1120672117750053
Publication Type
Journal Article
Date
Mar-01-2018
Author
Nina Hautala
Mira Siiskonen
Virva Hannula
Kaisu Järvinen
Aura Falck
Author Affiliation
Department of Ophthalmology, PEDEGO Research Unit and Medical Research Center, Oulu University Hospital, Oulu University, Oulu, Finland.
Source
Eur J Ophthalmol. 2018 Mar 01; :1120672117750053
Date
Mar-01-2018
Language
English
Publication Type
Journal Article
Abstract
The purpose of this study was to evaluate the visual function and the ophthalmic status of young Finnish adults with long duration of type 1 diabetes in relation to the history of the metabolic control.
A population-based cohort of children with type 1 diabetes examined in the Northern Ostrobothnia hospital district in 1989 (n?=?216) was re-examined 18?years later. High-contrast visual acuity (best-corrected visual acuity), contrast sensitivity, refractive error, lens status, intraocular pressure, stage of diabetic retinopathy and received treatments were evaluated. The metabolic control was reflected by the mean of glycated haemoglobin A1 or glycated haemoglobin A1c values of the years 1983-1989 and 1992-2007, respectively.
In all, 96 men and 76 women age 30?±?3?years with type 1 diabetes duration of 23?±?4?years attended the re-evaluation. About 60% (103/172) had normal best-corrected visual acuity and 3% had low vision. Contrast sensitivity was abnormal in two-thirds. Half had myopia. Four patients had cataract surgery. Low childhood glycated haemoglobin A1 was indicative, and favourable glycated haemoglobin A1c during youth was a significant predictor of better contrast sensitivity and ocular state in adulthood.
The majority of the patients have useful vision, although minor functional impairments are commonly detectable. Long duration of type 1 diabetes in association with non-optimal glycaemic control threatens visual function already at young adulthood. Thus, strong emphasis to control diabetes from onset is important in maintaining good visual function.
PubMed ID
29554811 View in PubMed
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Early glycaemic control for maintaining visual function in type 1 diabetes: The Oulu cohort study of diabetic retinopathy.

https://arctichealth.org/en/permalink/ahliterature296633
Source
Eur J Ophthalmol. 2018 Nov; 28(6):684-689
Publication Type
Journal Article
Date
Nov-2018
Author
Nina Hautala
Mira Siiskonen
Virva Hannula
Kaisu Järvinen
Aura Falck
Author Affiliation
Department of Ophthalmology, PEDEGO Research Unit and Medical Research Center, Oulu University Hospital, Oulu University, Oulu, Finland.
Source
Eur J Ophthalmol. 2018 Nov; 28(6):684-689
Date
Nov-2018
Language
English
Publication Type
Journal Article
Keywords
Adult
Cohort Studies
Contrast Sensitivity - physiology
Diabetes Mellitus, Type 1 - complications
Diabetic Retinopathy - physiopathology
Female
Finland
Glycated Hemoglobin A - metabolism
Humans
Lens, Crystalline - physiopathology
Male
Refractive Errors
Time Factors
Vision Disorders - physiopathology
Visual Acuity - physiology
Young Adult
Abstract
The purpose of this study was to evaluate the visual function and the ophthalmic status of young Finnish adults with long duration of type 1 diabetes in relation to the history of the metabolic control.
A population-based cohort of children with type 1 diabetes examined in the Northern Ostrobothnia hospital district in 1989 (n?=?216) was re-examined 18?years later. High-contrast visual acuity (best-corrected visual acuity), contrast sensitivity, refractive error, lens status, intraocular pressure, stage of diabetic retinopathy and received treatments were evaluated. The metabolic control was reflected by the mean of glycated haemoglobin A1 or glycated haemoglobin A1c values of the years 1983-1989 and 1992-2007, respectively.
In all, 96 men and 76 women age 30?±?3?years with type 1 diabetes duration of 23?±?4?years attended the re-evaluation. About 60% (103/172) had normal best-corrected visual acuity and 3% had low vision. Contrast sensitivity was abnormal in two-thirds. Half had myopia. Four patients had cataract surgery. Low childhood glycated haemoglobin A1 was indicative, and favourable glycated haemoglobin A1c during youth was a significant predictor of better contrast sensitivity and ocular state in adulthood.
The majority of the patients have useful vision, although minor functional impairments are commonly detectable. Long duration of type 1 diabetes in association with non-optimal glycaemic control threatens visual function already at young adulthood. Thus, strong emphasis to control diabetes from onset is important in maintaining good visual function.
PubMed ID
29554811 View in PubMed
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The Finnish national guideline for diagnosis, treatment and follow-up of patients with wet age-related macular degeneration.

https://arctichealth.org/en/permalink/ahliterature286088
Source
Acta Ophthalmol. 2017 07;95(A105 Suppl):1-9
Publication Type
Article
Date
07-2017
Author
Raimo Tuuminen
Hannele Uusitalo-Järvinen
Vesa Aaltonen
Nina Hautala
Sulevi Kaipiainen
Nina Laitamäki
Marko Ollila
Jari Rantanen
Satu Välimäki
Raija Sipilä
Tanja Laukkala
Jorma Komulainen
Petri Tommila
Ilkka Immonen
Anja Tuulonen
Kai Kaarniranta
Source
Acta Ophthalmol. 2017 07;95(A105 Suppl):1-9
Date
07-2017
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Angiogenesis Inhibitors - adverse effects - therapeutic use
Bevacizumab - adverse effects - therapeutic use
Diagnostic Techniques, Ophthalmological
Female
Finland
Follow-Up Studies
Humans
Intravitreal Injections
Laser Coagulation
Male
Photochemotherapy
Ranibizumab - adverse effects - therapeutic use
Receptors, Vascular Endothelial Growth Factor - therapeutic use
Recombinant Fusion Proteins - adverse effects - therapeutic use
Vascular Endothelial Growth Factor A - antagonists & inhibitors
Visual Acuity - physiology
Wet Macular Degeneration - diagnosis - therapy
Abstract
Age-related macular degeneration (AMD) is the main cause of visual impairment in developed countries. Several improvements in the visualization of posterior segment of the eye together with the introduction of intravitreal anti-VEGF treatment have revolutionized the prognosis of the wet form of AMD (wAMD). Increasing incidence of wAMD together with the limited resources of society and of the healthcare system poses challenges for the provision and development of care. In context of these current aspects, we aimed to set evidence-based medical guidelines for diagnosis, treatment and follow-up of patients with wAMD.
PubMed ID
28686003 View in PubMed
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A four-year prospective study on intraocular pressure in relation to phacoemulsification cataract surgery.

https://arctichealth.org/en/permalink/ahliterature146757
Source
Acta Ophthalmol. 2011 Nov;89(7):614-6
Publication Type
Article
Date
Nov-2011
Author
Aura Falck
Nina Hautala
Nina Turunen
Pentti Juhani Airaksinen
Author Affiliation
Department of Ophthalmology, Oulu University Hospital, Oulu, Finland. Aura.Falck@ppshp.fi
Source
Acta Ophthalmol. 2011 Nov;89(7):614-6
Date
Nov-2011
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Blood Pressure - physiology
Body mass index
Cataract - etiology
Female
Follow-Up Studies
Heart Rate - physiology
Humans
Intraocular Pressure - physiology
Male
Middle Aged
Phacoemulsification
Postoperative Period
Prospective Studies
Time Factors
Tonometry, Ocular
Abstract
To follow up prospectively the intraocular pressure (IOP) of healthy eyes with senile cataract undergoing phacoemulsification surgery over a duration of 4 years.
Thirty-five patients entering first eye cataract surgery had IOP measured by applanation tonometry pre-operatively and on day 1, at 1 month, 6 months, 1 year, 2 years and 4 years after surgery at 9 a.m. and again at 2 p.m. in the Department of Ophthalmology, Oulu University Hospital. Thirty-four patients attended the 1-year checkup, and the 2- and 4-year results are available for 31.
The pre-operative IOP was 16.0 (SD 4.3, range 6-25) mmHg in the morning and 16.4 (SD 4.0, range 8-25.5) mmHg in the afternoon. On the first postoperative day, the IOP was 2.1 ± 5.6 mmHg higher than before surgery (p = 0.029). At 1 month, the IOP morning measurement had decreased 2.8 ± 3.6 mmHg, and in the afternoon, the decrease was 3.0 ± 2.7 mmHg from the pre-operative level. At 6 months, the decrease was 3.3 ± 2.7 mmHg in the morning and 3.6 ± 2.7 mmHg in the afternoon, at 1 year, 3.2 ± 3.0 mmHg and 3.5 ± 3.2 mmHg, at 2 years, 3.2 ± 2.4 mmHg and 3.1 ± 2.8 mmHg, and at the 4-year postoperative checkup, 3.6 ± 3.4 mmHg and 3.6 ± 2.7 mmHg, respectively (p = 0.000 for all time-points).
IOP decreases by about 3 mmHg (16-23% from the pre-operative IOP level) after phacoemulsification and remains at this reduced level with no trend towards an increase during 4 years.
PubMed ID
20003107 View in PubMed
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Health-related quality of life of Finnish patients with diabetes.

https://arctichealth.org/en/permalink/ahliterature286157
Source
Scand J Public Health. 2016 Dec;44(8):765-771
Publication Type
Article
Date
Dec-2016
Author
Carolin Schanner
Aura Falck
Antti Keskitalo
Nina Hautala
Source
Scand J Public Health. 2016 Dec;44(8):765-771
Date
Dec-2016
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Diabetes Mellitus, Type 1 - therapy
Diabetes mellitus, type 2 - therapy
Diabetic Retinopathy - diagnosis
Female
Finland
Humans
Male
Mass Screening
Middle Aged
Quality of Life
Surveys and Questionnaires
Young Adult
Abstract
This study evaluated the influence of diabetes on the health-related quality of life (HRQoL) scores of adult patients with diabetes in northern Finland.
A total of 3771 patients of the population of 10,264 patients aged ?15 years with the right for reimbursement of the cost of diabetes medication attended fundus photography screening for retinopathy in 2012. The 15D HRQoL scores and data on age, sex, type and duration of diabetes were gathered concurrently. The results were compared with the 15D scores reported in Finnish population studies.
The 15D score was obtained from 2461 patients aged 60±14 years; 20% had type 1 diabetes (T1D). The mean±SD 15D index was 0.930±0.079 in patients with T1D and their mean±SD age was 46±15 years. The mean±SD 15D index of the patients with type 2 diabetes (T2D) was 0.890±0.100 and their mean±SD age was 63±11 years. The 15D index was no lower than in the Finnish general population in either patient group or in any age group. However, the 15D score was negatively influenced by an increasing duration of diabetes in both patients with T1D and patients with T2D. No sex difference was found.
The mean HRQoL score of patients with diabetes in this study is comparable with that of the general population of equal age. Neither the type of diabetes nor sex independently affected the HRQoL score, but a longer duration of diabetes seemed to impair the HRQoL score. Current diabetes care appears to maintain a normal HRQoL score in this diabetic population in Finland.
PubMed ID
27655783 View in PubMed
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Health-related quality of life--using the 15D instrument--of young adults with type 1 diabetes since childhood. Population-based Oulu cohort study of diabetic retinopathy.

https://arctichealth.org/en/permalink/ahliterature259207
Source
Acta Ophthalmol. 2014 May;92(3):205-8
Publication Type
Article
Date
May-2014
Author
Virva Hannula
Nina Hautala
Harri Sintonen
Aura Falck
Source
Acta Ophthalmol. 2014 May;92(3):205-8
Date
May-2014
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Child
Child, Preschool
Diabetes Mellitus, Type 1 - complications - psychology
Diabetic Retinopathy - epidemiology - etiology - psychology
Female
Finland - epidemiology
Follow-Up Studies
Humans
Male
Population Surveillance
Prevalence
Quality of Life
Questionnaires
Retrospective Studies
Visual acuity
Young Adult
Abstract
The aim of this study was to evaluate the health-related quality of life (HRQoL) of young adults with type 1 diabetes (T1D) since childhood using the 15D instrument. The possible impact of diabetic retinopathy (DR) and proliferative diabetic retinopathy (PDR) on the HRQoL was focused on.
During the years 1989-1990, the prevalence of DR was evaluated from ocular fundus photographs of a population-based cohort of children with T1D living in the Northern Osthrobothnia Hospital District, Finland. These 216 individuals were contacted 18 years later and invited for assessment of the 15D HRQoL as well as current stage of DR. The results were compared with age- and gender-standardized Finnish general population.
The 15D data were obtained from 123 patients aged 29±3 years with a duration of diabetes of 23±4 years. The mean 15D score was similar in the patients with T1D and the general population [0.954±0.062 versus 0.964±0.052, respectively (p=0.085)]. However, the subgroup of patients with PDR (N=38) had a statistically significantly lower mean 15D score than those subjects with nonproliferative or no DR [0.931±0.086 versus 0.965±0.044, respectively (p=0.026)].
Young adults with T1D since childhood had 15D HRQoL score equal to that of age- and gender-standardized general population as long as no more severe than nonproliferative DR was present. Presence of PDR, not T1D of long duration per se, significantly impaired the 15D score.
PubMed ID
23763986 View in PubMed
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Marked reductions in visual impairment due to diabetic retinopathy achieved by efficient screening and timely treatment.

https://arctichealth.org/en/permalink/ahliterature260887
Source
Acta Ophthalmol. 2014 Sep;92(6):582-7
Publication Type
Article
Date
Sep-2014
Author
Nina Hautala
Riittaliisa Aikkila
Juha Korpelainen
Antti Keskitalo
Anne Kurikka
Aura Falck
Risto Bloigu
Hannu Alanko
Source
Acta Ophthalmol. 2014 Sep;92(6):582-7
Date
Sep-2014
Language
English
Publication Type
Article
Keywords
Databases, Factual
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 2 - complications
Diabetic Retinopathy - classification - diagnosis - therapy
Finland - epidemiology
Humans
Incidence
Mass Screening
Mobile Health Units
Photography - methods
Registries
Telemedicine - methods
Vision Disorders - prevention & control
Visually Impaired Persons - statistics & numerical data
Abstract
Diabetic retinopathy (DR) is the most common complication of diabetes and needs to be diagnosed early to prevent severe sight-threatening retinopathy. Digital photography with telemedicine connections is a novel way to deliver cost-effective, accessible screening to remote areas. Screening for DR in a mobile eye examination unit (EyeMo) is compared to traditional service models (i.e. local municipal services or a commercial service provider). The quality of images, delays from screening to treatment, the stage of DR, coverage of screening and the rate of visual impairment due to DR are evaluated.
EyeMo utilizes telemedicine technology. The electronic databases of the hospital and information from the Finnish Register of Visual Impairment were used to determine delays and the rate of visual impairment.
Fourteen thousand eight hundred and sixty-six fundus photographs were taken in EyeMo in 2007-2011. Coverage reached 78% of potential clients. No DR was detected in 43%, mild background retinopathy in 23%, moderate or severe background retinopathy in 31% and proliferative retinopathy in 3% of the evaluations. The quality of images was higher (p 
PubMed ID
24131738 View in PubMed
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A mobile eye unit for screening of diabetic retinopathy and follow-up of glaucoma in remote locations in northern Finland.

https://arctichealth.org/en/permalink/ahliterature150618
Source
Acta Ophthalmol. 2009 Nov;87(8):912-3
Publication Type
Article
Date
Nov-2009

Prevalence of diabetic retinopathy in young adults with type 1 diabetes since childhood: the Oulu cohort study of diabetic retinopathy.

https://arctichealth.org/en/permalink/ahliterature262791
Source
Acta Ophthalmol. 2014 Dec;92(8):749-52
Publication Type
Article
Date
Dec-2014
Author
Nina Hautala
Virva Hannula
Tapani Palosaari
Tapani Ebeling
Aura Falck
Source
Acta Ophthalmol. 2014 Dec;92(8):749-52
Date
Dec-2014
Language
English
Publication Type
Article
Keywords
Adult
Age of Onset
Cohort Studies
Diabetes Mellitus, Type 1 - diagnosis - epidemiology
Diabetic Retinopathy - diagnosis - epidemiology
Female
Finland - epidemiology
Humans
Male
Prevalence
Time Factors
Young Adult
Abstract
To evaluate the prevalence and stage of diabetic retinopathy (DR) in a population-based cohort of young Finnish adults who have had type 1 diabetes (T1D) since childhood.
The cohort includes all 5- to 16-year-old patients with T1D who lived in the Northern Ostrobothnia Hospital District of Finland, in 1989 (n = 216). DR was evaluated from fundus photographs taken in 1989-1990 and again in 2007. The patients were 7 ± 4 years age (range 0-15 years) at the time of diagnosis of T1D, and the average duration of diabetes at the re-evaluation was 23 ± 4 years (range 17-32 years).
The prevalence of DR was analysed in 172 patients (80% of the original cohort) at 22-35 years. Proliferative DR (PDR) was observed in 35% (60/172) and non-proliferative DR in 59% (101/172), with no signs of DR being present in the remaining 6% (11/172) of the subjects. The prevalence of DR did not differ by gender (p = 0.356).
After the 18-year follow-up, a high prevalence of DR and PDR (94% and 35%, respectively) was found in patients who have had T1D since childhood, with no difference between the genders.
PubMed ID
24862935 View in PubMed
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12 records – page 1 of 2.