Skip header and navigation

1 records – page 1 of 1.

Cigar and pipe smoking and cancer risk in the european prospective investigation into cancer and nutrition.
Int J Cancer. 2010 Feb 16;
Publication Type
Va McCormack
A. Agudo
Cc Dahm
K. Overvad
A. Olsen
A. Tjonneland
R. Kaaks
H. Boeing
J. Manjer
M. Almquist
G. Hallmans
I. Johansson
Md Chirlaque
A. Barricarte
M. Dorronsoro
L. Rodriguez
Ml Redondo
Kt Khaw
N. Wareham
N. Allen
T. Key
E. Riboli
P. Boffetta
Author Affiliation
International Agency for Research on Cancer, Lyon, France.
Int J Cancer. 2010 Feb 16;
Publication Type
The carcinogenicity of cigar and pipe smoking is established but the effect of detailed smoking characteristics is less well defined. We examined the effects on cancer incidence of exclusive cigar and pipe smoking, and in combination with cigarettes, among 102395 men from Denmark, Germany, Spain, Sweden and UK in the EPIC cohort. Hazard ratios (HR) and their 95% confidence intervals (CI) for cancer during a median 9 year follow-up from ages 35-70 years were estimated using proportional hazards models. Compared to never smokers, HR of cancers of lung, upper aero-digestive tract and bladder combined was 2.2 (95% CI: 1.3, 3.8) for exclusive cigar smokers (16 cases), 3.0 (2.1, 4.5) for exclusive pipe smokers (33 cases) and 5.3 (4.4, 6.4) for exclusive cigarette smokers (1069 cases). For each smoking type, effects were stronger in current than in ex-smokers, and in inhalers than in non-inhalers. Ever smokers of both cigarettes and cigars (HR 5.7 (4.4, 7.3), 120 cases) and cigarettes and pipes (5.1 (4.1, 6.4), 247 cases) had as high a raised risk as had exclusive cigarette smokers. In these smokers, the magnitude of the raised risk was smaller if they had switched to cigars or pipes only (i.e. quit cigarettes) and had not compensated with greater smoking intensity. Cigar and pipe smoking is not a safe alternative to cigarette smoking. The lower cancer risk of cigar and pipe smokers as compared to cigarette smokers is explained by lesser degree of inhalation and lower smoking intensity. (c) 2010 UICC.
PubMed ID
20162568 View in PubMed
Less detail