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Hypogammaglobulinemia in Racing Alaskan Sled Dogs.

https://arctichealth.org/en/permalink/ahliterature94744
Source
J Vet Intern Med. 2009 Nov 17;
Publication Type
Article
Date
Nov-17-2009
Author
McKenzieE.
LupferC.
BanseH.
HinchcliffK.
LoveS.
Nelson JrS.
DavisM.
PaytonM.
PasteyM.
Author Affiliation
Department of Clinical Sciences, Oregon State University, Corvallis, OR.
Source
J Vet Intern Med. 2009 Nov 17;
Date
Nov-17-2009
Language
English
Publication Type
Article
Abstract
Background: Serum immunoglobulin dynamics have not been studied in racing sled dogs, despite hypoglobulinemia having been reported during racing events. Hypothesis/Objectives: Hypoglobulinemia in racing sled dogs is associated with decreases in serum IgA, IgE, IgG, and IgM concentrations during prolonged exercise. Animals: One hundred and fifty-seven Alaskan sled dogs that successfully completed a 1,000 mile race. Methods: Serum was obtained from 118 sled dogs within 1 month before the race and within 12 hours after completing the race. Serum also was obtained after 4 months of rest from 51 dogs that successfully completed the race, including 12 previously sampled dogs. Serum total protein ([TP]), albumin, and globulin ([Gl]) were measured, and serum IgA, IgE, IgG, and IgM were quantified by ELISA. Results: The proportion of dogs with [Gl]
PubMed ID
19925575 View in PubMed
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