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Acute low-back-pain patients exhibit a fourfold increase in sick leave for other disorders: a case-control study.

https://arctichealth.org/en/permalink/ahliterature67517
Source
J Spinal Disord. 1999 Aug;12(4):280-6
Publication Type
Article
Date
Aug-1999
Author
T. Seferlis
G. Németh
A M Carlsson
P. Gillström
Author Affiliation
Department of Orthopedics, Karolinska Hospital, Stockholm, Sweden.
Source
J Spinal Disord. 1999 Aug;12(4):280-6
Date
Aug-1999
Language
English
Publication Type
Article
Keywords
Absenteeism
Acute Disease
Adolescent
Adult
Case-Control Studies
Comorbidity
Disability Evaluation
Female
Humans
Low Back Pain - epidemiology - therapy
Male
Medical Records
Middle Aged
Occupations
Pain Measurement
Personality Inventory
Physical Examination
Prospective Studies
Questionnaires
Research Support, Non-U.S. Gov't
Sciatica - epidemiology
Sweden - epidemiology
Treatment Outcome
Abstract
One hundred eighty patients with acute low-back pain (LBP) were compared to 608 age- and sex-matched controls with regard to somatic and personality characteristics. The low-back-pain group had a fourfold increase (median) in sick-leave episodes for reasons other than spinal morbidity during the preceding 2 years. In the same period, the median number of episodes of sick leave for LBP was 1 in the patients and 0 in the controls. The mean number of days off for other reasons was 34 (median = 20.5) in the patients compared to 9 (median = 0) in the controls, and days off for LBP were 20 (median = 5) and 5 (median = 0), respectively. Analysis of other factors than those directly related to LBP disclosed significant differences in marital status and smoking habits between patients and controls. Furthermore, LBP patients estimated their work to be physically heavier. We conclude that medical intervention should focus not only on the spine, but also on a wide range of other aspects of the patient's situation. Even in the acute phase of LBP, the previous sick-leave records should be analyzed to provide adequate measures to prevent future sick leaves. Presently, the sociomedical costs for a subset of the population who repeatedly seek help for LBP are significantly higher than those for the non-LBP population.
PubMed ID
10451042 View in PubMed
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An epidemiologic study of Lyme disease in southern Sweden.

https://arctichealth.org/en/permalink/ahliterature14321
Source
N Engl J Med. 1995 Nov 16;333(20):1319-27
Publication Type
Article
Date
Nov-16-1995
Author
J. Berglund
R. Eitrem
K. Ornstein
A. Lindberg
A. Ringér
H. Elmrud
M. Carlsson
A. Runehagen
C. Svanborg
R. Norrby
Author Affiliation
Department of Community Health Sciences, University of Lund, Sweden.
Source
N Engl J Med. 1995 Nov 16;333(20):1319-27
Date
Nov-16-1995
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Animals
Child
Child, Preschool
Data Collection
Female
Humans
Incidence
Infant
Insect Bites and Stings - epidemiology
Ixodes
Lyme Disease - complications - epidemiology
Male
Middle Aged
Nervous System Diseases - etiology
Prospective Studies
Research Support, Non-U.S. Gov't
Seasons
Seroepidemiologic Studies
Sex Distribution
Sweden - epidemiology
Abstract
BACKGROUND. Lyme disease is the most common vector-borne infection in some temperate regions of the Northern Hemisphere. However, for most areas of endemic disease reliable epidemiologic data are sparse. METHODS. Over a one-year period, we conducted a prospective, population-based survey of cases of Lyme disease in southern Sweden. The diagnosis was made on the basis of the presence of erythema migrans at least 5 cm in diameter or characteristic clinical manifestations such as arthritis, neuroborreliosis, and carditis. RESULTS. We identified 1471 patients with Lyme disease, for an overall annual incidence of 69 cases per 100,000 inhabitants. The incidence varied markedly according to geographic region, and there were several areas where disease was widely prevalent. The incidence varied according to age, with the highest rates among people 5 to 9 and 60 to 74 years of age, but not according to sex. The most frequent clinical manifestation was erythema migrans (seen in 77 percent of all cases), followed by neuroborreliosis (16 percent) and arthritis (7 percent). Carditis was rare. A preceding tick bite was reported by 79 percent of the patients. Bites in the head and neck region were more common among children than among adults and were associated with an increased risk of neuroborreliosis. CONCLUSIONS. Lyme disease is very common in southern Sweden, with a relatively high frequency of neurologic complications and arthritis. With the exception of the low incidence of carditis, the pattern of disease we found in Sweden was similar to that reported in the United States.
Notes
Comment In: N Engl J Med. 1996 Mar 21;334(12):8038592568
PubMed ID
7566023 View in PubMed
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Antimicrobial resistance in colonizing group B Streptococci before the implementation of a Swedish intrapartum antibiotic prophylaxis program.

https://arctichealth.org/en/permalink/ahliterature100491
Source
Eur J Clin Microbiol Infect Dis. 2010 Oct;29(10):1195-201
Publication Type
Article
Date
Oct-2010
Author
M. Granlund
P. Axemo
K. Bremme
A-L Bryngelsson
M. Carlsson Wallin
C-M Ekström
S. Håkansson
B. Jacobsson
K. Källén
E. Spetz
I. Tessin
Author Affiliation
Department of Clinical Bacteriology, Umeå University Hospital, 901 85 Umeå, Sweden. Margareta.Granlund@climi.umu.se
Source
Eur J Clin Microbiol Infect Dis. 2010 Oct;29(10):1195-201
Date
Oct-2010
Language
English
Publication Type
Article
Keywords
Anti-Bacterial Agents - pharmacology
Bacterial Typing Techniques
Carrier State - microbiology
DNA, Bacterial - genetics
Drug Resistance, Bacterial
Female
Genes, Bacterial
Humans
Infant, Newborn
Microbial Sensitivity Tests - methods
Pregnancy
Pregnancy Complications, Infectious - microbiology
Rectum - microbiology
Serotyping
Skin - microbiology
Streptococcal Infections - microbiology
Streptococcus agalactiae - drug effects - isolation & purification
Sweden
Vagina - microbiology
Abstract
The prevalence of antibiotic resistance and their genetic determinants in colonizing group B streptococci (GBS) sampled in a Swedish nationwide survey was examined. In five GBS isolates (1.3%), kanamycin/amikacin resistance and the presence of the aphA-3 gene was identified. Three of these isolates carried the aad-6 gene and were streptomycin-resistant. Screening with kanamycin and streptomycin 1,000-?g disks enabled a rapid and easy detection of these isolates. In all, 312/396 (79%) GBS were tetracycline-resistant and 95% of the examined isolates harbored the tetM gene. Among the 22 (5.5%) GBS resistant to erythromycin and/or clindamycin, the ermB gene was detected in nine isolates (41%) and erm(A/TR) in ten isolates (45%). A high level of erythromycin and clindamycin resistance with minimum inhibitory concentrations (MICs) >256?mg/L was found in four serotype V isolates that harbored ermB. The erythromycin/clindamycin resistance was distributed among all of the common serotypes Ia, Ib, II, III, IV, and V, but was not present in any of the 44 serotype III isolates associated to clonal complex 17. Screening for penicillin resistance with 1-?g oxacillin disks showed a homogenous population with a mean inhibition zone of 20?mm. A change in the present oxacillin breakpoints for GBS is suggested.
PubMed ID
20706855 View in PubMed
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Apgar score and perinatal death after one previous caesarean delivery.

https://arctichealth.org/en/permalink/ahliterature96853
Source
BJOG. 2010 Aug;117(9):1088-97
Publication Type
Article
Date
Aug-2010
Author
M. Carlsson Wallin
P. Ekström
K. Marsál
K. Källén
Author Affiliation
Department of Obstetrics and Gynaecology, Ystad Hospital, Kristianstadsvägen 3, 271 82 Ystad, Sweden. marie.carlsson.wallin@gmail.com
Source
BJOG. 2010 Aug;117(9):1088-97
Date
Aug-2010
Language
English
Publication Type
Article
Abstract
OBJECTIVE: To assess the impact of the indication for a previous caesarean section on the outcome of a subsequent delivery. DESIGN: Population-based cohort study. SETTING: Sweden. POPULATION: Women with two deliveries between 1987 and 2007 identified using the Swedish Medical Birth Registry. METHODS: The outcome of 69 133 pregnancies after one caesarean section was compared with the outcome of 487 610 pregnancies following one vaginal delivery. The indication for the first caesarean section was estimated using a new hierarchical system based on information from birth records. MAIN OUTCOME MEASURES: Perinatal death, low Apgar score (less than seven at 5 minutes). RESULTS: Infants of women with one previous caesarean section were at increased risk of low Apgar score compared with infants of women with one previous vaginal delivery (OR, 2.0; 95% CI, 1.9-2.1). The risk estimate was reduced when adjustment for maternal and fetal/infant characteristics was made (OR, 1.6; 95% CI, 1.5-1.8). The corresponding crude and adjusted odds ratios for perinatal death were 1.6 (95% CI, 1.4-1.7) and 1.1 (95% CI, 1.0-1.2), respectively. The infant outcome of the delivery after one caesarean section was mainly dependent on the indication for the first-delivery caesarean section and, when no medical indication was present, no increase in risk was detected. CONCLUSIONS: Infants of women with one previous caesarean section were at increased risk of low Apgar score and/or perinatal death compared with infants of women with one previous vaginal delivery. The results suggest that medical conditions, not the previous caesarean section per se, contributed to the increase in risk.
PubMed ID
20497412 View in PubMed
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Availability of insulin pump therapy in clinical practice.

https://arctichealth.org/en/permalink/ahliterature129930
Source
Diabet Med. 2012 Aug;29(8):1055-9
Publication Type
Article
Date
Aug-2012
Author
B-M Carlsson
P Nord Andersson
J. Alnervik
J. Carstensen
M. Lind
Author Affiliation
Diabetes Section of Medicine, SÃ?S-Hospital Organization, Skene, Uddevalla, Sweden.
Source
Diabet Med. 2012 Aug;29(8):1055-9
Date
Aug-2012
Language
English
Publication Type
Article
Keywords
Adult
Ambulatory Care
Diabetes Mellitus, Type 1 - drug therapy
Female
Humans
Hypoglycemic Agents - administration & dosage
Insulin - administration & dosage
Insulin Infusion Systems - supply & distribution
Male
Middle Aged
Odds Ratio
Sweden
Young Adult
Abstract
To examine the availability of insulin pump therapy in patients with Type 1 diabetes.
Patients using insulin pumps among a cohort of 7224 patients with Type 1 diabetes were studied.
In logistic regression, used to evaluate variables not changing over time among the total cohort, use of insulin pumps varied by outpatient clinic (P
Notes
Comment In: Diabet Med. 2012 Aug;29(8):97122803777
PubMed ID
22050599 View in PubMed
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Body mass index, Mini Nutritional Assessment, and their association with five-year mortality in very old people.

https://arctichealth.org/en/permalink/ahliterature270671
Source
J Nutr Health Aging. 2015 Apr;19(4):461-7
Publication Type
Article
Date
Apr-2015
Author
M. Burman
S. Säätelä
M. Carlsson
B. Olofsson
Y. Gustafson
C. Hörnsten
Source
J Nutr Health Aging. 2015 Apr;19(4):461-7
Date
Apr-2015
Language
English
Publication Type
Article
Keywords
Aged, 80 and over
Body mass index
Cause of Death
Female
Finland - epidemiology
Humans
Male
Malnutrition - diagnosis - epidemiology - mortality
Nutrition Assessment
Nutritional Status - physiology
Prevalence
Prospective Studies
Residence Characteristics
Sex Characteristics
Sweden - epidemiology
Abstract
to investigate the prevalence of malnutrition and the association between Body Mass Index (BMI), Mini Nutritional Assessment (MNA) and five-year mortality in a representative population of very old (>85 years) people.
A prospective cohort study.
A population-based study of very old people in northern Sweden and western Finland, living in institutional care or in the community.
Out of 1195 potential participants, 832 were included (mean age 90.2±4.6 years).
Nutritional status was assessed using BMI and MNA and the association of those two variables with five-year mortality was analyzed.
The mean BMI value for the whole population was 25.1±4.5 kg/m2, with no difference between genders (P=0.938). The mean MNA score was 22.5±4.6 for the whole sample, and it was lower for women than for men (P
PubMed ID
25809811 View in PubMed
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A case of Q fever acquired in Sweden and isolation of the probable ethiological agent, Coxiella burnetii from an indigenous source.

https://arctichealth.org/en/permalink/ahliterature195805
Source
Scand J Infect Dis. 2000;32(6):605-7
Publication Type
Article
Date
2000
Author
S. Rustscheff
L. Norlander
A. Macellaro
A. Sjöstedt
S. Vene
M. Carlsson
Author Affiliation
Department of Internal Medicine, Värnamo General Hospital, Sweden.
Source
Scand J Infect Dis. 2000;32(6):605-7
Date
2000
Language
English
Publication Type
Article
Keywords
Animals
Anti-Bacterial Agents - therapeutic use
Coxiella burnetii - isolation & purification
DNA, Bacterial - analysis
Diagnosis, Differential
Doxycycline - therapeutic use
Electrophoresis, Agar Gel
Housing, Animal
Humans
Male
Middle Aged
Poaceae - microbiology
Polymerase Chain Reaction
Q Fever - diagnosis - drug therapy - transmission
Sweden
Abstract
Serologically verified indigenous Q fever is described in a 52-y-old male, who presented with persistent fever, muscle and joint pain, headache and non-purulent cough. Institution of doxycycline resulted in prompt recovery. Coxiella burnetii was isolated from mouldy hay in a barn. The strain differs from previously isolated ones in Sweden.
PubMed ID
11200368 View in PubMed
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Changes in total energy intake and macronutrient composition after bariatric surgery predict long-term weight outcome: findings from the Swedish Obese Subjects (SOS) study.

https://arctichealth.org/en/permalink/ahliterature284710
Source
Am J Clin Nutr. 2017 Jul;106(1):136-145
Publication Type
Article
Date
Jul-2017
Author
Noora Kanerva
Ingrid Larsson
Markku Peltonen
Anna-Karin Lindroos
Lena M Carlsson
Source
Am J Clin Nutr. 2017 Jul;106(1):136-145
Date
Jul-2017
Language
English
Publication Type
Article
Keywords
Adult
Bariatric Surgery
Diet, Reducing
Dietary Carbohydrates - administration & dosage - pharmacology
Dietary Fats - administration & dosage - pharmacology
Dietary Proteins - administration & dosage - pharmacology
Energy intake
Feeding Behavior
Female
Humans
Male
Middle Aged
Obesity
Obesity, Morbid - diet therapy - surgery - therapy
Prospective Studies
Surveys and Questionnaires
Sweden
Weight Loss
Abstract
Background: Approximately 20-30% of obese patients do not achieve successful weight outcomes after bariatric surgery.Objective: We examined whether short-term changes (=0.5 y postsurgery) in energy intake and macronutrient composition after bariatric surgery could predict 10-y weight change.Design: Participants were recruited from the Swedish Obese Subjects (SOS) study, which was a matched (nonrandomized) prospective trial that compared bariatric surgery with usual care for obese patients. A total of 2010 patients who underwent bariatric surgery were included in the study. Physical examinations (e.g., weight) and questionnaires (e.g., dietary questionnaire) were completed before and 0.5, 1, 2, 3, 4, 6, 8, and 10 y after surgery. For the main analytic strategy, a linear mixed model was implemented, which included repeated measures with a random intercept and an unstructured covariance matrix.Results: Short-term changes in energy intake (P
Notes
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PubMed ID
28515062 View in PubMed
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Chronic lymphocytic leukaemia at a county hospital in southern Sweden.

https://arctichealth.org/en/permalink/ahliterature22598
Source
Med Oncol. 1996 Jun;13(2):95-101
Publication Type
Article
Date
Jun-1996
Author
V. Hjalmar
M. Carlsson
E. Kimby
Author Affiliation
Department of Medicine, County Hospital Ryhov, Jönköping, Sweden.
Source
Med Oncol. 1996 Jun;13(2):95-101
Date
Jun-1996
Language
English
Publication Type
Article
Keywords
Aged
Cell Transformation, Neoplastic
Female
Hospitals, County
Humans
Incidence
Leukemia, Lymphocytic, Chronic - pathology - physiopathology - therapy
Male
Opportunistic Infections - complications
Retrospective Studies
Sex Distribution
Survival Rate
Sweden - epidemiology
Abstract
We have studied retrospectively patients with chronic lymphocytic leukaemia (CLL), at Ryhov, J?nk?ping, Sweden during a 10-year-period. This unselected cohort (n = 59) from a well-defined geographical area is suitable for describing the natural course of the disease. The CLL was diagnosed incidentally in the majority of cases. Median-age at diagnosis was 71 years and the male:female ratio was 1.3:1. The diagnosis was based on morphology in 66% and in 33% immunophenotyping specified the diagnosis of B- or T-CLL. At diagnosis 66% were in Rai-stage O/I or Binet-stage A. There were 36% untreated patients and their median-survival was 108 months compared with 84 months for the whole cohort and 72 months for the treated patients. Malignancies were seen in 31% and infections in 83%. Intercurrent diseases played an important role in the survival. During the observation time, only 54% of the deceased patients had died due to the CLL.
PubMed ID
9013472 View in PubMed
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Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)--adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes.

https://arctichealth.org/en/permalink/ahliterature47715
Source
Diabetologia. 2001 May;44(5):629-36
Publication Type
Article
Date
May-2001
Author
M. Carlsson
M. Orho-Melander
J. Hedenbro
L C Groop
Author Affiliation
Department of Endocrinology Malmö University Hospital, Sweden.
Source
Diabetologia. 2001 May;44(5):629-36
Date
May-2001
Language
English
Publication Type
Article
Keywords
Alleles
Amino Acid Substitution
Arginine
Blood Glucose - metabolism
Blood pressure
Comparative Study
Diabetes Mellitus, Type 2 - blood - genetics
European Continental Ancestry Group
Fatty Acids, Nonesterified - blood
Female
Genotype
Glutamic Acid
Glutamine
Homozygote
Humans
Insulin - blood
Lipoproteins, HDL Cholesterol - blood
Male
Middle Aged
Nuclear Family
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Receptors, Adrenergic, beta-2 - chemistry - genetics
Receptors, Adrenergic, beta-3 - chemistry - genetics
Reference Values
Research Support, Non-U.S. Gov't
Sweden
Triglycerides - blood
Tryptophan
Variation (Genetics)
Abstract
AIMS/HYPOTHESIS: Higher NEFA concentrations predict Type II (non-insulin-dependent) diabetes mellitus but it is not known whether higher NEFA concentrations are genetically determined or reflect coexisting obesity. To address this question we studied whether common variants in two genes encoding for key regulators of lipolysis, the beta2- and beta3- adrenoceptors (B2AR and B3AR) are associated with NEFA concentrations and Type II diabetes. METHODS: A total of 1054 Swedish subjects with varying degrees of glucose tolerance were genotyped for the Gln27Glu variant in the B2AR and for the Trp64Arg variant in the B3AR genes using PCR-RFLP. RESULTS: The B2AR Gln27 allele was more frequent in 219 Type II diabetic patients than in 237 non-diabetic subjects (59.8 % vs 52.3 %; OR = 1.72, p = 0.02) while there was no significant difference in the frequency of the B3AR Arg64 allele. Subjects homozygous for the protective alleles (Glu27 and Trp64) had, however, a lower prevalence of diabetes than subjects with other genotype combinations (OR = 0.58, p = 0.03). Among sibling pairs discordant for the B2AR Gln27Glu polymorphism, siblings with an excess of the Gln27 allele had higher fasting insulin (n = 217; p = 0.02) and NEFA concentrations (107 sex-matched pairs; p = 0.01) than siblings with an excess of the Glu27 allele. Among sibling pairs discordant for the B3AR Trp64Arg variant, siblings with the Arg64 allele had higher 2 h glucose (n = 48; p = 0.01) and NEFA concentrations (16 pairs matched for sex; p
PubMed ID
11380082 View in PubMed
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57 records – page 1 of 6.