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[Clinico-genealogical and genetic-mathematical research on cancer of the cervix uteri]

https://arctichealth.org/en/permalink/ahliterature23302
Source
Tsitol Genet. 1995 Mar-Apr;29(2):54-60
Publication Type
Article
Author
L M Isakova
K P Hanina
O V Osins'ka
A B Vinnyts'ka
Source
Tsitol Genet. 1995 Mar-Apr;29(2):54-60
Language
Ukrainian
Publication Type
Article
Keywords
Adult
Alleles
English Abstract
Environmental Exposure - adverse effects
Female
Genetic Techniques
Humans
Pedigree
Phenotype
Questionnaires
Research Support, Non-U.S. Gov't
Ukraine
Uterine Cervical Neoplasms - etiology - genetics
Abstract
Analysis of the family histories of 179 patients with cancer of uterine cervix was conducted to detect the influence of their heredity and environmental factors on the development of malignant tumors using clinical-genealogical and genetic-mathematical methods. Decomposition of phenotypic variance was used as a basis for detecting the contribution of genetic component (2.92%) and random environmental component (97.08%) which reflected the influence of exogenic risk factors of development of uterine cervix cancer. Clinico-genealogical analysis of probands' pedigrees was the basis for detecting association of malignant neoplasms in lung and uterine cervix epithelia.
PubMed ID
7631425 View in PubMed
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