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Clinical severity and prognosis of hand eczema.
Br J Dermatol. 2009 Jun;160(6):1229-36
Publication Type
Hald M.
Agner T.
Blands J.
Veien N K
Laurberg G.
Avnstorp C.
Menné T.
Kaaber K.
Kristensen B.
Kristensen O.
Andersen K E
Paulsen E.
Thormann J.
Sommerlund M.
Nielsen N H
Johansen J D
Author Affiliation
National Allergy Research Centre, Gentofte University Hospital, Hellerup, Denmark.
Br J Dermatol. 2009 Jun;160(6):1229-36
Publication Type
BACKGROUND: Hand eczema (HE) is a frequent, long-lasting disease with both personal and societal repercussions. Consequently, more information is needed on factors that maintain symptoms. OBJECTIVES: In this study, patients with HE were followed for 6 months from the first visit to a dermatologist to identify factors associated with severe disease and a poor prognosis. METHODS: Study participants were 799 patients with HE from nine dermatological clinics in Denmark. Severity assessment of the HE was done at baseline and at the 6-month follow-up using the Hand Eczema Severity Index (HECSI) and by patients using a self-administered photographic guide. Additional information was obtained from a baseline questionnaire. RESULTS: At baseline, 60.3% assessed their HE as moderate to very severe using the self-administered photographic guide compared with 36.1% at follow-up. The mean HECSI value decreased from 19.9 points at baseline to 11.2 points at follow-up (P or = 1 positive patch test (P
PubMed ID
19416249 View in PubMed
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