Skip header and navigation

2 records – page 1 of 1.

Across six nations: stressful events in the lives of children.

https://arctichealth.org/en/permalink/ahliterature35027
Source
Child Psychiatry Hum Dev. 1996;26(3):139-50
Publication Type
Article
Date
1996
Author
K. Yamamoto
O L Davis
S. Dylak
J. Whittaker
C. Marsh
P C van der Westhuizen
Author Affiliation
University of Colorado at Denver 80217, USA.
Source
Child Psychiatry Hum Dev. 1996;26(3):139-50
Date
1996
Language
English
Publication Type
Article
Keywords
Adolescent
Australia
Chi-Square Distribution
Child
Child Psychology
Cross-Cultural Comparison
Europe
Female
Humans
Life Change Events
Male
Reference Values
Stress, Psychological
United States
Abstract
A total of 1,729 children (2nd-9th grades) in South Africa, Iceland, Poland, Australia, the U.K., and the U.S.A. rated 20 events in terms of how upsetting they are. Save in Poland, the ratings were in close agreement (r, .85-.97), placing the loss of parent at the top and a new baby sibling at the bottom. In Poland, the baby's arrival led the list. Even so, what was seen as quite upsetting fell everywhere in the same two categories--experiences that threaten one's sense of security and those that occasion personal denigration and embarrassment.
PubMed ID
8819876 View in PubMed
Less detail

Haplotype distribution of class II MHC genes in Mexican patients with systemic lupus erythematosus.

https://arctichealth.org/en/permalink/ahliterature204004
Source
Scand J Rheumatol. 1998;27(5):373-6
Publication Type
Article
Date
1998
Author
C. Bekker-Mendez
J K Yamamoto-Furusho
G. Vargas-Alarcón
D. Ize-Ludlow
J. Alcocer-Varela
J. Granados
Author Affiliation
Department of Immunology and Rheumatology, Instituto Nacional de la Nutrición Salvador Zubirán, Mexico City, Mexico.
Source
Scand J Rheumatol. 1998;27(5):373-6
Date
1998
Language
English
Publication Type
Article
Keywords
DNA - analysis
European Continental Ancestry Group - genetics
Gene Frequency
Genes, MHC Class II - genetics
Genetic Predisposition to Disease
Genetics, Population
HLA-DQ Antigens - genetics
Haplotypes
Humans
Indians, North American - genetics
Linkage Disequilibrium
Lupus Erythematosus, Systemic - genetics
Mexico
Phenotype
Abstract
The objective of this project was to determine the association of the DQA1*0501 allele in the susceptibility to develop systemic lupus erythematosus (SLE) in Mexicans. Frequencies of generic MHC Class II genes (HLA-DR, DQA and DQB1) were determined by DNA typing in 58 Mexican mestizo SLE patients and 96 ethnically matched controls. Statistical analysis was performed by chi-square and Fisher's exact tests. The DQA1*0501 allele was found to be in linkage disequillibrium with H LA-DR3, DR11, and DR14. This explains the lack of association with the allele alone, and the evident strong association of SLE with the [HLA-DR3-DQA1*0501-DQB1*0201] and [HLA-DR1-DQA1*0101-DQB1*0501] haplotypes. It was also found a significant decrease (protection) of the [HLA-DR8-DQA1*0401-DQB1*0402] haplotype which is known to be a characteristic haplotype among the indigenous population of Mexico. These data shows that the susceptibility to SLE in Mexicans is more strongly influenced by the MHC haplotypes than by single alleles. The suggestion that these genes do not act alone but in combination, makes the identification of haplotypes mandatory.
PubMed ID
9808402 View in PubMed
Less detail