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Acute effects of particulate air pollution on respiratory admissions: results from APHEA 2 project. Air Pollution and Health: a European Approach.

https://arctichealth.org/en/permalink/ahliterature15434
Source
Am J Respir Crit Care Med. 2001 Nov 15;164(10 Pt 1):1860-6
Publication Type
Article
Date
Nov-15-2001
Author
R W Atkinson
H R Anderson
J. Sunyer
J. Ayres
M. Baccini
J M Vonk
A. Boumghar
F. Forastiere
B. Forsberg
G. Touloumi
J. Schwartz
K. Katsouyanni
Author Affiliation
Department of Public Health Sciences, St. George's Hospital Medical School, London, United Kingdom. atkinson@sghms.ac.uk
Source
Am J Respir Crit Care Med. 2001 Nov 15;164(10 Pt 1):1860-6
Date
Nov-15-2001
Language
English
Publication Type
Article
Keywords
Acute Disease
Adolescent
Adult
Age Distribution
Aged
Air Pollution - adverse effects - analysis
Asthma - epidemiology - etiology
Child
Child, Preschool
Emergencies
England - epidemiology
France - epidemiology
Health status
Health Surveys
Humans
Infant
Infant, Newborn
Italy - epidemiology
Middle Aged
Netherlands - epidemiology
Ozone - adverse effects - analysis
Particle Size
Patient Admission - statistics & numerical data - trends
Population Surveillance
Pulmonary Disease, Chronic Obstructive - epidemiology - etiology
Regression Analysis
Research Support, Non-U.S. Gov't
Seasons
Spain - epidemiology
Sweden - epidemiology
Time Factors
Urban Health - statistics & numerical data - trends
Weather
Abstract
The APHEA 2 project investigated short-term health effects of particles in eight European cities. In each city associations between particles with an aerodynamic diameter of less than 10 microm (PM(10)) and black smoke and daily counts of emergency hospital admissions for asthma (0-14 and 15-64 yr), chronic obstructive pulmonary disease (COPD), and all-respiratory disease (65+ yr) controlling for environmental factors and temporal patterns were investigated. Summary PM(10) effect estimates (percentage change in mean number of daily admissions per 10 microg/m(3) increase) were asthma (0-14 yr) 1.2% (95% CI: 0.2, 2.3), asthma (15-64 yr) 1.1% (0.3, 1.8), and COPD plus asthma and all-respiratory (65+ yr) 1.0% (0.4, 1.5) and 0.9% (0.6, 1.3). The combined estimates for Black Smoke tended to be smaller and less precisely estimated than for PM(10). Variability in the sizes of the PM(10) effect estimates between cities was also investigated. In the 65+ groups PM(10) estimates were positively associated with annual mean concentrations of ozone in the cities. For asthma admissions (0-14 yr) a number of city-specific factors, including smoking prevalence, explained some of their variability. This study confirms that particle concentrations in European cities are positively associated with increased numbers of admissions for respiratory diseases and that some of the variation in PM(10) effect estimates between cities can be explained by city characteristics.
PubMed ID
11734437 View in PubMed
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Lung function and indicators of exposure to indoor and outdoor particulate matter among asthma and COPD patients.

https://arctichealth.org/en/permalink/ahliterature148673
Source
Occup Environ Med. 2010 Jan;67(1):2-10
Publication Type
Article
Date
Jan-2010
Author
J J de Hartog
J G Ayres
A. Karakatsani
A. Analitis
H Ten Brink
K. Hameri
R. Harrison
K. Katsouyanni
A. Kotronarou
I. Kavouras
C. Meddings
J. Pekkanen
G. Hoek
Author Affiliation
IRAS, Utrecht University, PO Box 80178, 3508 TD Utrecht, the Netherlands.
Source
Occup Environ Med. 2010 Jan;67(1):2-10
Date
Jan-2010
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Air Pollutants - analysis
Air Pollution - analysis
Air Pollution, Indoor - analysis
Asthma - physiopathology
Cities
England - epidemiology
Female
Finland - epidemiology
Forced Expiratory Volume - physiology
Greece - epidemiology
Humans
Inhalation Exposure - analysis
Male
Middle Aged
Netherlands - epidemiology
Particle Size
Particulate Matter - analysis
Peak Expiratory Flow Rate - physiology
Pulmonary Disease, Chronic Obstructive - physiopathology
Respiratory Function Tests
Vital Capacity - physiology
Abstract
Misclassification of exposure related to the use of central sites may be larger for ultrafine particles than for particulate matter 1 year. Daily concentrations of particle number, PM(2.5) and PM(10) were measured at a central site in each city and both inside and outside the subjects' homes.
Daily average particle number concentrations ranged between 2100 and 66 100 particles/cm(3). We found no association between 24 h average particle number or particle mass concentrations and FVC, FEV(1) and PEF. Substituting home outdoor or home indoor concentrations of particulate air pollution instead of the central site measurements did not change the observed associations. Analyses restricted to asthmatics also showed no associations.
No consistent associations between lung function and 24 h average particle number or particle mass concentrations were found in panels of patients with mild to moderate COPD or asthma. More detailed exposure assessment did not change the observed associations. The lack of association could be due to the high prevalence of medication use, limited ability to assess lagged effects over several days or absence of an effect.
PubMed ID
19736175 View in PubMed
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