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[Angiographic results of primary angioplasty in acute myocardial infarction]

https://arctichealth.org/en/permalink/ahliterature53939
Source
Tidsskr Nor Laegeforen. 2001 Mar 10;121(7):780-3
Publication Type
Article
Date
Mar-10-2001
Author
N E Kløw
B. Bendz
J. Eritsland
P. Hoffman
S. Stavnes
K H Stensaeth
E. Søvik
M. Brekke
A. Mangschau
Author Affiliation
Hjerte-lungesenteret, Ullevål sykehus, 0407 Oslo. n.e.klow@ioks.uio.no
Source
Tidsskr Nor Laegeforen. 2001 Mar 10;121(7):780-3
Date
Mar-10-2001
Language
Norwegian
Publication Type
Article
Keywords
Adult
Aged
Angioplasty, Transluminal, Percutaneous Coronary
Coronary Angiography
English Abstract
Female
Humans
Male
Middle Aged
Myocardial Infarction - therapy
Treatment Outcome
Abstract
BACKGROUND: Percutaneous angioplasty is an alternative to thrombolysis to reestablish coronary blood flow in patients with transmural myocardial infarction. At present, this treatment option is not widely accepted in Norway. MATERIAL AND METHODS: From 1996 to 1998, one hundred consecutive patients were treated with angioplasty for acute transmural infarction. The angiography showed one-vessel disease in 55%, two-vessel in 25%, and multivessel in 20%. The infarct related artery was the LAD in 44%, the CX in 14%, the RCA in 41%, and bypass graft in one. 92% had TIMI 0 or 1 flow. Stent was placed in 73%, GPIIb/IIIa was used in 11% and temporary pacemaker placed in 5%. RESULTS: Successful angioplasty was performed in 95%, 3% was not done, and 2% failed. Peripheral stenoses were treated in 15% and stenoses in other arteries in 10%. Complications and events within 24 hours related to the angioplasty were seen in 9%. CONCLUSION: Primary angioplasty for acute myocardial infarction can be done with high primary success, good short-term results and few complications.
PubMed ID
11301697 View in PubMed
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Elevated levels of PAI-1 activity and t-PA antigen are associated with newly diagnosed abnormal glucose regulation in patients with ST-elevation myocardial infarction.

https://arctichealth.org/en/permalink/ahliterature134082
Source
J Thromb Haemost. 2011 Aug;9(8):1468-74
Publication Type
Article
Date
Aug-2011
Author
E C Knudsen
I. Seljeflot
M. Abdelnoor
J. Eritsland
A. Mangschau
C. Müller
H. Arnesen
G Ø Andersen
Author Affiliation
Center for Clinical Heart Research, Oslo University Hospital, Ullevål, Oslo, Norway. knev@uus.no
Source
J Thromb Haemost. 2011 Aug;9(8):1468-74
Date
Aug-2011
Language
English
Publication Type
Article
Keywords
Biological Markers - blood
Blood Glucose - metabolism
Chi-Square Distribution
Diabetes Mellitus, Type 2 - blood - diagnosis
Female
Glucose Intolerance - blood - diagnosis
Glucose Tolerance Test
Hemostasis
Humans
Inpatients
Logistic Models
Male
Myocardial Infarction - blood - diagnosis
Norway
Odds Ratio
Peptide Fragments - blood
Plasminogen Activator Inhibitor 1 - blood
Prospective Studies
Prothrombin
Time Factors
Tissue Plasminogen Activator - blood
Up-Regulation
von Willebrand Factor - metabolism
Abstract
Both Type 2 diabetes and cardiovascular disease have been associated with enhanced coagulation and suppressed fibrinolysis.
To investigate a possible relationship between selected hemostatic variables and abnormal glucose regulation (AGR) in patients with acute ST-elevation myocardial infarction (STEMI) without known diabetes and to study changes in selected hemostatic variables from baseline to follow-up in STEMI patients with or without AGR.
Plasminogen activator inhibitor-1 (PAI-1) activity, tissue plasminogen activator (t-PA) antigen, prothrombin fragment 1+2 (F(1+2)) and von Willebrand factor (vWF) were measured in fasting blood samples from 199 STEMI patients 16.5 h (median time) after admission and 3 months later. All patients were classified into normal glucose regulation (NGR) or AGR based on an oral glucose tolerance test at follow-up, according to the WHO criteria.
High PAI-1 activity (= 75th percentile) measured in-hospital was associated with AGR (n = 49) with an adjusted odds ratio of 2.2 (95% confidence interval, 1.1, 4.4). In addition, high levels of t-PA antigen (= 75th percentile) were associated with AGR (adjusted odds ratio, 3.5; 95% confidence inteval, 1.5, 8.2), but only in men. Changes in the levels of F(1+2) were significantly more pronounced in patients with AGR compared with NGR (adjusted P = 0.04).
Elevated levels of PAI-1 activity and t-PA antigen measured in-hospital in STEMI patients were associated with AGR classified at 3-month follow-up. Additionally, changes in the levels of F(1+2) were more pronounced in patients with AGR compared with NGR. The data suggest an enhanced prothrombotic state after an acute STEMI in patients with AGR without known diabetes.
PubMed ID
21624046 View in PubMed
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Ethnicity and acute myocardial infarction: risk profile at presentation, access to hospital management, and outcome in Norway.

https://arctichealth.org/en/permalink/ahliterature120919
Source
Vasc Health Risk Manag. 2012;8:505-15
Publication Type
Article
Date
2012
Author
M. Abdelnoor
J. Eritsland
C. Brunborg
S. Halvorsen
Author Affiliation
Unit of Biostatistics and Epidemiology, Oslo University Hospital Ullevaal, Oslo, Norway. michelab@online.no
Source
Vasc Health Risk Manag. 2012;8:505-15
Date
2012
Language
English
Publication Type
Article
Keywords
Aged
Cross-Sectional Studies
Ethnic Groups
Female
Follow-Up Studies
Health Services Accessibility
Hospital Mortality - trends
Hospitalization - trends
Humans
Male
Middle Aged
Myocardial Infarction - ethnology - surgery
Norway - epidemiology
Percutaneous Coronary Intervention - methods
Prognosis
Retrospective Studies
Risk factors
Treatment Outcome
Abstract
Previous studies in North America have shown ethnic variation in the presentation of acute myocardial infarction (AMI), and sex and racial differences in the management and outcome of AMI. In the present study, our aim was to investigate the risk profile of AMI for patients with minority background compared with indigenous Norwegians, at hospital presentation, and to investigate racial differences in hospital care and outcomes.
A dual-design study was adopted: a cross-sectional study to examine ethnic differences of risk prevalence at hospital presentation and a cohort study to estimate access to angiography, percutaneous coronary intervention (PCI), and hospital and long-term mortality. From a study population of 3105 patients with AMI presenting at Oslo University Hospital between January 1, 2006 and December 31, 2007, we identified 147 cases of AMI in patients with minority background and selected a random sample of 588 indigenous Norwegians with AMI as controls. Prognostic and explanatory strategies were used in the analysis.
Compared with indigenous Norwegians with AMI, AMI patients with minority background suffered their AMI 10 years younger, were generally male, were twice as likely to be smokers, three times as likely to have type 2 diabetes, had lower high-density lipoprotein levels. This group also had 50% less history of hypertension. In terms of hospital care, AMI patients with minority background had shorter times from onset of symptoms to PCI and the same frequency of access to angiography and acute PCI as indigenous Norwegians when adjusting for the confounding effect of age, sex, and nature of myocardial infarction with or without ST elevation.
At presentation to hospital, patients with minority background had a higher risk profile and a shorter time from onset of symptoms to admission to catheterization laboratory than indigenous Norwegians, but the same access to angiography and acute PCI during hospitalization.
Notes
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PubMed ID
22956878 View in PubMed
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[Long-term follow-up of 100 patients with acute myocardial infarction treated with angioplasty]

https://arctichealth.org/en/permalink/ahliterature49845
Source
Tidsskr Nor Laegeforen. 2001 Oct 20;121(25):2930-2
Publication Type
Article
Date
Oct-20-2001
Author
A. Mangschau
J. Eritsland
S. Stavnes
K. Sevre
K H Stenseth
N E Kløw
C. Müller
L. Sandvik
B. Bendz
Author Affiliation
Hjerte-lunge-senteret, Ullevål sykehus 0407 Oslo. arild.mangschau@ulleval.no
Source
Tidsskr Nor Laegeforen. 2001 Oct 20;121(25):2930-2
Date
Oct-20-2001
Language
Norwegian
Publication Type
Article
Keywords
Adult
Aged
Angioplasty, Transluminal, Percutaneous Coronary
English Abstract
Follow-Up Studies
Humans
Middle Aged
Myocardial Infarction - drug therapy - mortality - therapy
Norway - epidemiology
Patient Readmission
Recurrence
Abstract
BACKGROUND: There is little information available on long-term follow up of patients treated with primary angioplasty for acute myocardial infarction. MATERIAL AND METHODS: 100 consecutive patients with acute ST-elevation myocardial infarction and symptoms of less than six hours' duration were treated with primary angioplasty. Clinical examination was performed in 97 patients and exercise stress test in 74 patients 11-37 months (mean 20 months) later. Patients were observed for survival up to 48 months. RESULTS: 24 patients had been rehospitalized, 16 because of chest pain. 77 patients were treated with beta blocker, 83 with statins, and 95 with antithrombotic medication. 84 patients were in NYHA (New York's Heart Association's classification's) class I at follow-up examination. Three patients died. 11 patients had a serious event, reinfarction (n = 3) or need for revascularization (n = 8) during the first 13 months. Total cumulative mortality rates after one and three years were 3% (95% CI 1-8) and 11% (95% CI 6-19). INTERPRETATION: The good initial results in primary angioplasty are maintained in long-term follow-up. This is in accordance with reports from centres abroad.
PubMed ID
11715775 View in PubMed
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Predictors of enhanced well-being after coronary artery bypass surgery.

https://arctichealth.org/en/permalink/ahliterature54714
Source
J Intern Med. 1996 Jan;239(1):69-73
Publication Type
Article
Date
Jan-1996
Author
S. Steine
E. Laerum
J. Eritsland
H. Arnesen
Author Affiliation
Department of General Practice, University of Oslo, Norway.
Source
J Intern Med. 1996 Jan;239(1):69-73
Date
Jan-1996
Language
English
Publication Type
Article
Keywords
Coronary Artery Bypass - psychology
Coronary Disease - psychology - surgery
Female
Humans
Male
Middle Aged
Predictive value of tests
Prognosis
Quality of Life
Questionnaires
Risk factors
Treatment Outcome
Abstract
OBJECTIVES. To assess patients' perception of the therapeutic outcome after coronary artery bypass surgery, and to find predictors for increased well-being. DESIGN. Self-administered questionnaires (Family APGAR and GHQ-30) were completed on admission and at the follow-up after 12 months, together with functional classification according to the NYHA index. SETTING. Ullevål University Hospital, Oslo, Norway, 1990-1992. SUBJECTS. Two hundred and thirteen patients with stable angina admitted for elective coronary artery bypass surgery. INTERVENTION. Elective coronary artery bypass surgery. MAIN OUTCOME MEASURES. Improved physical and psychosocial functioning after one year. RESULTS. One hundred and ninety-seven (92%) patients improved their NYHA class, while it remained stable or declined in 16 (8%) patients. Significantly fewer patients with mental distress were found at the follow-up than at the baseline examination (49 patients [23%] versus 80 patients [38%], respectively, P
PubMed ID
8551203 View in PubMed
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