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Comparison of coronary atherosclerosis in middle-aged Norwegian and Japanese men. An autopsy study.

https://arctichealth.org/en/permalink/ahliterature55576
Source
Lab Invest. 1987 Apr;56(4):451-6
Publication Type
Article
Date
Apr-1987
Author
L A Solberg
T. Ishii
J P Strong
M A Guzman
Y. Hosoda
S. Tsugane
W P Newman
R E Tracy
Source
Lab Invest. 1987 Apr;56(4):451-6
Date
Apr-1987
Language
English
Publication Type
Article
Keywords
Adult
Blood pressure
Cholesterol - blood
Comparative Study
Coronary Arteriosclerosis - epidemiology - pathology
Humans
Japan
Male
Middle Aged
Norway
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.
Risk
Triglycerides - blood
Abstract
We compared the extent of lesions in the coronary arteries of autopsied middle-aged men from Oslo, Norway, with lesions in autopsied men of similar ages in Tokyo, Japan. Certain risk factors for coronary heart disease as serum cholesterol, triglycerides, and blood pressure were also available from these men in the two locations. Our comparisons reveal large differences in the extent of atherosclerosis between Oslo and Tokyo, which are reflected in the levels of the risk factors, particularly serum cholesterol levels. Our findings suggest that preventive strategies could retard the development of atherosclerosis and coronary heart disease without the economic and nutritional problems that affect technically underdeveloped societies where atherosclerosis and coronary heart disease are not prevalent.
PubMed ID
3560868 View in PubMed
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Risk factors and atherosclerotic lesions. A review of autopsy studies.

https://arctichealth.org/en/permalink/ahliterature48915
Source
Arteriosclerosis. 1983 May-Jun;3(3):187-98
Publication Type
Article
Author
L A Solberg
J P Strong
Source
Arteriosclerosis. 1983 May-Jun;3(3):187-98
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aorta - pathology
Arteriosclerosis - complications - epidemiology - pathology
Autopsy
Cerebral Arteries - pathology
Cholesterol - blood
Coronary Disease - epidemiology
Coronary Vessels - pathology
Diabetes Complications
Diastole
Female
Humans
Hypertension - complications
Lipoproteins, HDL - blood
Lipoproteins, HDL Cholesterol
Louisiana
Male
Middle Aged
Norway
Research Support, U.S. Gov't, P.H.S.
Risk
Sex Factors
Smoking
Systole
Triglycerides - blood
Abstract
This review assesses the current status of knowledge concerning the relationship of risk factors to atherosclerotic lesions. Risk factors for atherosclerotic lesions per se need not necessarily be identical to those related to clinically overt coronary heart disease (CHD). This review is based on 1) autopsy studies where information risk factors was gathered in a retrospective fashion; and 2) autopsy studies where information on risk factors was gathered prospectively. In spite of differences in study designs and grading methods among the studies, the general findings were similar. Elevated serum cholesterol and blood pressure are positively and significantly related to atherosclerotic lesions. High density lipoprotein cholesterol is inversely related to coronary and probably also to cerebral atherosclerosis. Almost all studies indicate a significant association between cigarette smoking and degree of aortic atherosclerosis; a positive relationship between smoking and coronary atherosclerosis is found between obesity or physical activity and the degree of atherosclerosis. Data from the Community Pathology Study in New Orleans indicate that the average extent of coronary atherosclerosis in a population may be subject to changes within a relatively short period of time; these changes might be expected to parallel changes in risk factors in the population.
PubMed ID
6342587 View in PubMed
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11 records – page 1 of 2.