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63 records – page 1 of 7.

The acquired immunodeficiency syndrome (AIDS) in Denmark. A report from the Copenhagen study group of AIDS on the first 20 Danish patients.

https://arctichealth.org/en/permalink/ahliterature8796
Source
Acta Med Scand. 1985;217(2):213-24
Publication Type
Article
Date
1985
Author
J. Gerstoft
J O Nielsen
E. Dickmeiss
T. Rønne
P. Platz
L. Mathiesen
Source
Acta Med Scand. 1985;217(2):213-24
Date
1985
Language
English
Publication Type
Article
Keywords
Acquired Immunodeficiency Syndrome - epidemiology - immunology - transmission
Adult
Africa, Central
Denmark
Homosexuality
Humans
Male
Middle Aged
Travel
United States
Abstract
Twenty Danish patients with the acquired immunodeficiency syndrome (AIDS) had been diagnosed by January 1984, 14 of them after 1982. Eighteen patients were male homosexuals, 8 of whom had visited the USA after 1979, 2 were heterosexual males with a history of sexual contacts in Central Africa, suggesting a transmission of AIDS from woman to man. AIDS has not been observed in drug abusers, hemophiliacs or transfused non-risk persons in Denmark. The clinical picture varied according to the presence of Kaposi sarcoma or the type of opportunistic infections, but was in general similar to that reported from the USA. Investigation of T-lymphocyte subsets revealed that the AIDS patients differed from controls and healthy homosexual men by having either a very low number of helper cells or a low helper/suppressor cell ratio. Functional immunological studies revealed a decreased natural killer cell activity and decreased blast transformation by mitogens. The survival two years after diagnosis was 16%.
PubMed ID
3993435 View in PubMed
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Acute non-A, non-B hepatitis--clinical, epidemiological and histological characteristics.

https://arctichealth.org/en/permalink/ahliterature57022
Source
Scand J Infect Dis. 1980;12(3):165-9
Publication Type
Article
Date
1980
Author
P. Kryger
J. Aldershvile
P. Christoffersen
F. Hardt
E. Juhl
L R Mathiesen
J O Nielsen
H. Poulsen
Source
Scand J Infect Dis. 1980;12(3):165-9
Date
1980
Language
English
Publication Type
Article
Keywords
Acute Disease
Adolescent
Adult
Aged
Chronic Disease
Cytomegalovirus Infections - diagnosis
Denmark
Female
Follow-Up Studies
Hepatitis A - diagnosis - epidemiology - pathology
Hepatitis B - diagnosis - epidemiology - pathology
Hepatitis C - diagnosis - epidemiology - pathology
Hepatitis, Viral, Human - epidemiology
Humans
Male
Middle Aged
Research Support, Non-U.S. Gov't
Abstract
Among 73 consecutive patients with biopsy documented acute non-toxic hepatitis, half of the patients (49%) had acute type B hepatitis, while 27 patients (37%) had acute type A infection. One patient had a significant rise in antibodies against cytomegalovirus. The remaining 10 patients (14%) fulfilled the criteria of hepatitis type non-A, non-B. The main type of exposure for hepatitis A was visit to endemic hepatitis areas (41%), and for type B it was drug addiction (46%). Half of the patients with hepatitis non-A, non-B had no known hepatitis exposure while some had visited endemic hepatitis areas or were drug addicts. The patients with non-A, non-B hepatitis had significantly less biochemical changes as compared to the patients with hepatitis B. In contrast, the histological findings showed the greatest activity in the biopsies from patients with hepatitis B and non-A, non-B. Follow-up liver biopsies in half of the patients with non-A, non-B hepatitis showed no signs of chronic active liver disease. It is concluded that hepatitis type non-A, non-B is a significant problem in Denmark.
PubMed ID
6254139 View in PubMed
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[Acute viral hepatitis--a constant threat]

https://arctichealth.org/en/permalink/ahliterature56782
Source
Ugeskr Laeger. 1995 Oct 9;157(41):5699
Publication Type
Article
Date
Oct-9-1995
Author
K. Krogsgaard
J O Nielsen
Source
Ugeskr Laeger. 1995 Oct 9;157(41):5699
Date
Oct-9-1995
Language
Danish
Publication Type
Article
Keywords
Acute Disease
Denmark - epidemiology
Hepatitis, Viral, Human - epidemiology - transmission
Humans
Risk factors
PubMed ID
7571104 View in PubMed
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[Acute viral hepatitis, non-A, non-B type in a hepatological department Copenhagen Hepatitis Acuta Program]

https://arctichealth.org/en/permalink/ahliterature57026
Source
Ugeskr Laeger. 1979 Dec 10;141(50):3434-7
Publication Type
Article
Date
Dec-10-1979

Antibody to HIV in patients with acute hepatitis B in the period 1975-1984.

https://arctichealth.org/en/permalink/ahliterature8746
Source
Scand J Infect Dis. 1987;19(2):167-72
Publication Type
Article
Date
1987
Author
M. Arendrup
B O Lindhardt
K. Krogsgaard
J. Gaub
J O Nielsen
Source
Scand J Infect Dis. 1987;19(2):167-72
Date
1987
Language
English
Publication Type
Article
Keywords
Acquired Immunodeficiency Syndrome - complications - epidemiology - immunology
Acute Disease
Adult
Antibodies, Viral - analysis
Denmark
Female
Follow-Up Studies
HIV - immunology
HIV Antibodies
Hepatitis B - complications - immunology
Humans
Immunity, Cellular
Male
Retrospective Studies
Time Factors
Abstract
In order to elucidate the time when HIV was introduced into a population of patients with acute hepatitis B, serum samples collected in the period 1975-1984 from 331 patients with hepatitis B were analysed for the presence of antibody to HIV (anti-HIV). Anti-HIV was not detected in any of the serum samples from 97 females. 5/234 serum samples from males (2%) were repeatedly positive. Anti-HIV was first demonstrated in 1978, 3 years before the first patients with AIDS were recognized in Denmark. None of the 4 Danish patients with anti-HIV developed AIDS during a follow-up period of 1-7 years. However, at the time of follow-up in 1985 3 had decreased cell mediated immunity. The hepatitis B infection had an uncomplicated course in 4/5 patients with anti-HIV. One patient had a protracted delta hepatitis and was a HBsAg carrier before as well as after the acute hepatitis. Thus, the HIV infection did not cause any complicated course in this study.
PubMed ID
3475776 View in PubMed
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[Are prehistoric epidemics reflected in the genetic variability of Danes and in current pathogenesis of HIV infections?]

https://arctichealth.org/en/permalink/ahliterature7623
Source
Ugeskr Laeger. 1998 Dec 21;160(52):7585-8
Publication Type
Article
Date
Dec-21-1998
Author
J. Eugen-Olsen
A. Møller-Jensen
J O Nielsen
Author Affiliation
H:S Hvidovre Hospital, infektionsmedicinsk afdeling, klinisk forskningsenhed. jeo@biobase.dk
Source
Ugeskr Laeger. 1998 Dec 21;160(52):7585-8
Date
Dec-21-1998
Language
Danish
Publication Type
Article
Keywords
Denmark - epidemiology
Disease Outbreaks - history
Gene Deletion
HIV Infections - genetics
History, 19th Century
History, 20th Century
History, Ancient
Humans
Paintings - history
Receptors, CCR5 - genetics
Variation (Genetics)
PubMed ID
9889676 View in PubMed
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Children admitted for observation for suspected meningitis. Problems in diagnosis in general practice.

https://arctichealth.org/en/permalink/ahliterature38367
Source
Scand J Prim Health Care. 1988 Nov;6(4):229-32
Publication Type
Article
Date
Nov-1988
Author
B. Nielsen
H T Sørensen
J O Nielsen
Author Affiliation
Department of Internal Medicine, Thisted Hospital, Denmark.
Source
Scand J Prim Health Care. 1988 Nov;6(4):229-32
Date
Nov-1988
Language
English
Publication Type
Article
Keywords
Child
Child, Preschool
Denmark
Diagnosis, Differential
Family Practice
Female
Humans
Male
Meningitis - diagnosis
Meningitis, Haemophilus - diagnosis
Meningitis, Meningococcal - diagnosis
Meningitis, Pneumococcal - diagnosis
Referral and Consultation
Retrospective Studies
Spinal Puncture
Abstract
Infectious diseases in children are common in general practice. It is crucial not to overlook a case of purulent meningitis, and the aim of the present study was to evaluate and suggest ways of improving the diagnostic ability of the general practitioners in this respect. During a seven-year period 157 children under the age of 16 years, out of a population of 10,500 children, were referred from general practice to a district hospital for observation with symptoms and signs that suggested a possible diagnosis of meningitis. Seventy-eight underwent lumbar puncture, but only 14 of them received a final diagnosis of purulent meningitis. During the same period three other children proved to be cases of purulent meningitis, though they had been referred with other diagnosis. Twenty children had aseptic meningitis or encephalitis. The clinical findings in the groups of children with and without purulent meningitis were very similar, but an impaired level of consciousness and presence of petechiae were commoner in the former. Children with purulent meningitis had a significantly shorter duration of symptoms than children without meningitis. The present study could not suggest any ways of improving the referral procedures.
PubMed ID
3231942 View in PubMed
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Cost-effectiveness of introducing a third-generation test for HBsAg in Danish blood donors.

https://arctichealth.org/en/permalink/ahliterature56944
Source
Liver. 1986 Jun;6(3):173-7
Publication Type
Article
Date
Jun-1986
Author
P. Wantzin
L. Skovgaard
N. Tygstrup
J O Nielsen
H. Soerensen
E. Dybkjaer
Source
Liver. 1986 Jun;6(3):173-7
Date
Jun-1986
Language
English
Publication Type
Article
Keywords
Blood Donors
Blood Transfusion - adverse effects
Comparative Study
Cost-Benefit Analysis
Counterimmunoelectrophoresis
Denmark
Hepatitis B - etiology - prevention & control
Hepatitis B Surface Antigens - analysis - immunology
Humans
Mass Screening - economics - methods
Radioimmunoassay
Research Support, Non-U.S. Gov't
Abstract
Owing to the low incidence of hepatitis B in Denmark, screening of blood donors for HBsAg has mostly been done by immunoelectroosmophoresis (IEOP). The purpose of the present study was to carry out a cost-effectiveness analysis prior to the introduction of a third-generation test for HBsAg in Danish blood donors. The analysis was performed on data from a subsequent screening of 48 750 blood units by radioimmunoassay (RIA) 3 weeks after donation. The RIA-pos., IEOP-neg. blood donors identified in the study were evaluated by a follow-up examination, and the recipients of RIA-pos., IEOP-neg. blood units were monitored for up to 9 months as to the development of acute hepatitis B. The study shows that the estimated cost for each prevented case of transfusion-associated hepatitis B in Denmark is US$ 1100 when screening donors not previously tested by a third-generation technique, and US$ 240 000 when screening donors tested before by this technique.
PubMed ID
3091978 View in PubMed
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63 records – page 1 of 7.