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[10-year dynamics of attitude to health problems in the male population of Novosibirsk (epidemiological study based on the WHO MONICA program)]

https://arctichealth.org/en/permalink/ahliterature74937
Source
Ter Arkh. 2003;75(1):27-30
Publication Type
Article
Date
2003
Author
V V Gafarov
V A Pak
I V Gagulin
T D Babina
Source
Ter Arkh. 2003;75(1):27-30
Date
2003
Language
Russian
Publication Type
Article
Keywords
Adult
English Abstract
Health Status Indicators
Humans
Male
Middle Aged
Population Surveillance
Siberia - epidemiology
World Health Organization
Abstract
AIM: To evaluate changes for a decade in the attitude of men in Novosibirsk to health problems. MATERIAL AND METHODS: WHO program MONICA has covered males aged 25-64 years (a representative sample from the population in one of the districts of Novosibirsk city). A total of 3 trials were made (in 1984, 1988 and 1994) which included questioning, registration of ECG, arterial pressure, height, body mass, biochemical tests of the blood. RESULTS: Attitude of men to their health depended on their age. There was a trend to evaluate their health as more and more poor in men at the age of 25-43 and 35-44 years. In the group of 45-54-year-olds positive assessment of health was encountered 1.9 times more frequently, but the difference was not significant. At the age 55-64 years a growing number of men tend to assess their health as good. Since 1994 alcoholics among the elderly men grew in number as a response to the social and economic crisis. CONCLUSION: The change in health evaluation from negative to positive in older men may relate to less intensive work.
PubMed ID
12652951 View in PubMed
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23-year dynamics (1994-2016) relationships to its health, behavioral characteristics and  prevention of cardiovascular diseases among women 25-44 years in Russia /Siberia.

https://arctichealth.org/en/permalink/ahliterature301119
Source
Ter Arkh. 2018 Feb 14; 90(1):36-44
Publication Type
Journal Article
Date
Feb-14-2018
Author
V V Gafarov
D O Panov
E A Gromova
I V Gagulin
A V Gafarova
E A Krymov
Author Affiliation
FSBI Institute of Internal and Preventive Medicine, Novosibirsk, Russia.
Source
Ter Arkh. 2018 Feb 14; 90(1):36-44
Date
Feb-14-2018
Language
English
Publication Type
Journal Article
Keywords
Adult
Aged
Attitude to Health
Cardiovascular diseases
Female
Health Behavior
Humans
Middle Aged
Reproducibility of Results
Risk factors
Russia
Siberia
Surveys and Questionnaires
Abstract
To determine the 23-year dynamics (1994-2016) of attitudes toward one's health, behavioral characteristics and the prevention of cardiovascular diseases in an open population among women 25-44 years old in Russia / Siberia (Novosibirsk).
In the framework of the third screening of the MONICA program for the study of trends and control of cardiovascular diseases and the MONICA-psychosocial (MOPSY) subprogram, in 1994 a random representative sample of women aged 25-64 years of age from one from the districts of Novosibirsk (n = 870, the average age is 45.4±0.4 years); in the age group 25-44 years - 284 persons. In 2016 years. in the framework of screening studies on the budgetary issue of NIITPM No. gos. reg. 01201282292, a random representative sample of women aged 25-44 years old in the same district of Novosibirsk (n = 540) was examined. Attitude to their health, behavioral characteristics and the prevention of cardiovascular diseases were studied using the "Knowledge and attitude to their health" scale, validated for the Russian population under the WHO "MONICA" program. The chi-square test (x2) was used to calculate the indices. The criterion of statistical significance was the reliability of the result at p
PubMed ID
30701756 View in PubMed
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[An epidemiological study of ischemic heart disease, vascular brain diseases and their risk factors in an open population of 25- to 64-year olds in Novosibirsk]

https://arctichealth.org/en/permalink/ahliterature55297
Source
Ter Arkh. 1991;63(9):80-3
Publication Type
Article
Date
1991
Author
V V Gafarov
T E Vinogradova
M I Voevoda
I V Gagulin
E G Markevich
T A Filimonova
T G Klimenkova
Source
Ter Arkh. 1991;63(9):80-3
Date
1991
Language
Russian
Publication Type
Article
Keywords
Adult
Age Factors
Cerebrovascular Disorders - epidemiology
Coronary Disease - epidemiology
English Abstract
Humans
Middle Aged
Risk factors
Sex Factors
Siberia - epidemiology
Urban Population - statistics & numerical data
World Health Organization
Abstract
To study the incidence of coronary heart disease (CHD), cerebrovascular diseases (CVD), combined pathology (CHD and CVD), and their risk factors such as arterial hypertension (AH), overweight (OW), hypercholesterolemia (HC), and tobacco smoking in the same population, a random representative sample of male and female populations were examined in three districts of Novosibirsk. AH and tobacco smoking were found predominant among men, whereas OW and HC among women. It turned out that almost every fourth person out of the men and almost every second woman suffered from cardiovascular diseases. In the men, the CHD/CVD ratio was 1:1, that in the women, was 1:7. In the men and women, suffering from combined pathology, AH occurred more frequently as compared to those with CHD or CVD alone. OW promoted the development of CVD and combined pathology in women to a greater degree, whereas HC favoured the development of CHD and CVD in men.
PubMed ID
1759233 View in PubMed
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Depression and risk of cardiovascular diseases among males aged 25-64 (WHO MONICA--psychosocial).

https://arctichealth.org/en/permalink/ahliterature160876
Source
Alaska Med. 2007;49(2 Suppl):255-8
Publication Type
Article
Date
2007
Author
H A Gromova
V V Gafarov
I V Gagulin
Author Affiliation
Collaborative Laboratory of Epidemiology of Cardiovascular Diseases (Institute of Internal Medicine, Novosibirsk, Russia. grom@irs.ru
Source
Alaska Med. 2007;49(2 Suppl):255-8
Date
2007
Language
English
Publication Type
Article
Keywords
Adult
Cardiovascular Diseases - epidemiology - etiology
Comorbidity
Depression - complications
Humans
Hypertension - etiology
Incidence
Male
Middle Aged
Myocardial Infarction - etiology
Prevalence
Prospective Studies
Risk
Risk assessment
Russia - epidemiology
Stroke - etiology
Abstract
To study the influence of depression on risk of cardiovascular diseases development during 10 years in non-organized male population aged 25-64.
Within the framework of the MONICA--psychosocial program a representative sample of 657 men 25-64 years old (1994 year) was examined. Depression was measured at baseline with the use of the MONICA--psychosocial Interview Depression scale. The incidence of new cases of AH, MI and stroke was revealed in the WHO "Registry MI" and "Registry stroke" 10-year follow-up. Cox is a proportional regression model that was used for estimation of RR.
The proportion of depression in the cohort of men with AH was 28.9%, with MI--65.8% and of men with stroke 70.6%. The relative risk of development of AH, MI, stroke during the first five years of supervision in a group with the high level of depression as compared to those in whom depression was not observed was 6.7 times (p
PubMed ID
17929644 View in PubMed
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[Dynamics of sleep disorders and health characteristics, relationship to prevention of cardiovascular diseases among women 25-44 years old in Russia/Siberian].

https://arctichealth.org/en/permalink/ahliterature300487
Source
Zh Nevrol Psikhiatr Im S S Korsakova. 2018; 118(4. Vyp. 2):43-54
Publication Type
Journal Article
Author
V V Gafarov
E A Gromova
I V Gagulin
A V Gafarova
E A Krymov
D O Panov
Author Affiliation
Institute of Internal and Preventive Medicine - Branch of Institute of Cytology and Genetics, Novosibirsk, Russia; Collaborative laboratory of Cardiovascular Diseases Epidemiology, Novosibirsk, Russia.
Source
Zh Nevrol Psikhiatr Im S S Korsakova. 2018; 118(4. Vyp. 2):43-54
Language
Russian
Publication Type
Journal Article
Keywords
Adult
Aged
Cardiovascular Diseases - epidemiology - etiology
Female
Humans
Middle Aged
Risk factors
Russia - epidemiology
Siberia - epidemiology
Sleep Wake Disorders - complications - epidemiology
Abstract
To determine the 23-year dynamics (1994-2017) of the relationship between sleep disorders (SD) and attitudes toward their health, behavioral characteristics and prevention of cardiovascular diseases in the open population among women 25-44 years old in Russia/Siberia (Novosibirsk).
In the third screening of the WHO program 'Study of trends and control of cardiovascular diseases' MONICA, 'the subprogram' MONICA-psychosocial (MOPSY), a random representative sample of women, aged 25-64 years, of one of the areas of Novosibirsk (n=870) was examined in 1994. In 2016, in the framework of screening studies, a random representative sample of women, aged 25-44 years, was examined in the same district of Novosibirsk (n=668). Sleep assessment was performed using the Jenkins Sleep Questionnaire. Attitude to their health, behavioral characteristics and prevention of cardiovascular diseases were studied using the 'Knowledge and attitude to one's health' scale proposed by the WHO 'MONICA' program and validated in the Russian population.
The prevalence of SD among women 25-44 years old decreased from 59.6% to 47.3% from 1994 to 2017. The proportion of women with SD, who consider themselves not completely healthy or sick, decreased from 86.2% to 67.6%. The majority of women with SD (57%) consider the high probability of getting a serious illness in the next 5-10 years, but only 7% of women with SD have regular screening tests. The share of those, who were satisfied with medical care, increased by 2017 but does not exceed 13%. In case of malaise, only 1 in 10 women apply to a doctor, as in 1994. The intensity of work of young women with SD is higher compared to those with good sleep; they more often (more than 40%) do additional work, are more responsible. An increase in the level of family stress among women with SD is characterized by more frequent illness/death of a loved one, rare opportunity to relax in home environment. Recently, the number of women smokers has increased, their physical activity has decreased, and their adherence to dietary recommendations has been low.
Over the studied period, there were: the decrease in SD; in case of SD, a more careful attitude towards one's health in the sick; the increase in the intensity of work, responsibility at work, stress in the family. Adverse, statistically significant trends towards increasing in the intensity of smoking, reducing physical activity, low adherence to compliance with dietary recommendations in women with SD have been obtained.
???? ????????????. ?????????? 23-?????? ???????? (1994-2017) ??????????? ????????? ??? (??) ?? ????????? ? ?????? ????????, ???????????? ????????-?????????? ??????????? ? ????????????? ????????????? ? ???????? ????????? ?????? 25-44 ??? ? ??????. ???????? ? ??????. ? ?????? ????????? ???????? ????????? ? ???????? ????????-?????????? ??????????? MONICA ? ???????????? MONICA-??????????????? (MOPSY) (???) ? 1994 ?. ???? ??????????? 870 ?????? ? ???????? 25-64 ??? ?????? ????????????. ? 2016 ?. ? ?????? ???? ???????? 668 ?????? ? ???????? 25-44 ??? ???? ?? ??????. ?????? ??? ????????? ??? ?????? ????? ?????????. ??? ??????????? ????????? ? ?????? ????????, ???????????? ????????-?????????? ??????????? ? ????????????? ????????????? ???????????? ???????????????? ????? ??? MONICA '?????? ? ????????? ? ?????? ????????'. ??????????. ?????????????????? ?? ????? ?????? 25-44 ??? ? ?????? ? 1994 ?? 2017 ?. ????????? ? 59,6 ?? 47,3%. ???? ?????? ? ??, ??????? ??????? ???? ?? ?????? ????????? ??? ????????, ??????????? ? 86,2 ?? 67,6%. ??????????? ?????? ? ?? (57%) ??????? ??????? ??????????? ???????? ????????? ???????? ? ????????? 5-10 ???, ?? ?????? 7% ?????????? ??????????? ????????????????? ??????????. ???? ??????????????? ??????????? ????????????? ? 2017 ?. ???????????, ?? ?? ????????? 13%. ? ?????? ??????????? ?? ??????? ????? ? ????? ?????????? ?????? 1 ?? 10 ??????, ??? ? ? 1994 ?. ????????????? ????? ?????? ???????? ???????? ? ?? ???? ?? ????????? ????????? ??? ??; ??? ???? (????? 40%) ????????? ?????????????? ??????, ????? ????? ??????? ???????????????. ?????????? ?????? ????????? ??????? ????? ?????? ? ?? ??????????????? ????? ?????? ????????/??????? ???????, ?????? ???????????? ????????? ? ???????? ??????????. ??????????? ?????????? ????? ???????, ???????? ?????????? ??????????, ???? ?????? ?????????????? ? ?????????? ??????????? ????????????. ??????????. ?????????? ? ???????? ????? ??????: ???????? ?????????????????? ??; ????? ?????????? ????????? ? ?????? ???????? ? ??????????; ?????????? ????????????? ?????, ??????????????? ?? ??????, ??????? ? ?????. ???????? ??????????????? ????????????? ???????? ?????? ??? ?? ? ?????????? ??????? ???????, ???????? ?????????? ??????????, ????? ?????? ?????????????? ? ?????????? ??????????? ????????????.
PubMed ID
30059051 View in PubMed
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Effect of stress at work on the risk of cardiovascular diseases among the population of 25-64 years in Russia/Siberia (WHO program "MONICA-psychosocial").

https://arctichealth.org/en/permalink/ahliterature300439
Source
Ter Arkh. 2019 Mar 04; 91(1):13-18
Publication Type
Journal Article
Date
Mar-04-2019
Author
V V Gafarov
E A Gromova
D O Panov
I V Gagulin
A V Gafarova
Author Affiliation
Interdepartmental Laboratory for Epidemiology of Cardiovascular Diseases, Novosibirsk, Russia.
Source
Ter Arkh. 2019 Mar 04; 91(1):13-18
Date
Mar-04-2019
Language
English
Publication Type
Journal Article
Keywords
Adult
Aged
Cardiovascular Diseases - epidemiology - psychology
Female
Humans
Male
Middle Aged
Prevalence
Prospective Studies
Risk factors
Russia - epidemiology
Siberia
Stress, Psychological
Stroke
Workplace
Abstract
The aim of the study was to determine the impact of stress on work on the risk of cardiovascular disease over a 16-year period in an open population of 25-64 years in Russia/Siberia.
A random representative sample of the population of both sexes of 25-64 years old in Novosibirsk in 1994 (men: n=657, 44.3±0.4 years, response - 82.1%, women: n=689, 45.4±0.4 years, response - 72.5%). The screening survey program included: registration of socio-demographic data, determination of stress at work (Karazek scale). The period of prospective follow-up of participants was 16 years. The study identified the following "end points": the first cases of myocardial infarction (MI), stroke.
A high level of stress at work was in 29.5% of men and 31.6% of women, the average level in 48.9% of men and 50.7% of women (?2=2.574, ?=2, p=0.276). The risk of developing MI for a 16-year period, among people experiencing stressful situations at work, was: in men, HR=3.592, and women HR=3.218 (95% CI 1.146-9.042); stroke risk - among men, HR=2.603 (95% CI 1.06-4.153) in women HR=1.956 (95% CI 1.008-3.795). In multivariate analysis, in men with stress at work, the risk of MI among men was HR=1.15 (95% CI 0.6-2.2), among women - HR=2.543 (95% CI 1.88-7.351); risk of stroke, was in men, HR=3.8 (95% CI 1.6-8.8), in women - HR=1.95 (95% CI 0.984-3.887). The risk of stroke was higher among single, divorced and widowed men, HR=4.2 (95% CI 1.5-13.2), and in women with secondary or primary education, HR=3 (95% CI 0.852-11.039).
It was established that a high level of stress at work is not gender-specific; the risk of developing MI over a 16-year period is higher in women than in men, stroke in men; the risk of myocardial infarction and stroke in both sexes is affected by the social gradient.
PubMed ID
31090365 View in PubMed
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[Gender differences in health awareness and attitudes as a subjective-objective health index in the population of Russia/Siberia (WHO MONICA-psychosocial program, HAPIEE project)].

https://arctichealth.org/en/permalink/ahliterature262337
Source
Ter Arkh. 2015;87(1):14-26
Publication Type
Article
Date
2015
Author
V V Gafarov
E A Gromova
I V Gagulin
A V Gafarova
D O Panov
Source
Ter Arkh. 2015;87(1):14-26
Date
2015
Language
Russian
Publication Type
Article
Keywords
Adult
Aged
Attitude to Health
Cardiovascular Diseases - epidemiology - etiology - psychology
Female
Health Knowledge, Attitudes, Practice
Health Status Indicators
Humans
Male
Mass Screening
Middle Aged
Questionnaires
Risk factors
Russia - epidemiology
Sex Characteristics
Siberia - epidemiology
Socioeconomic Factors
World Health Organization
Abstract
To establish gender differences in health attitudes and awareness of risk factors for cardiovascular diseases in an open 25-64-year-old population of Russia/Siberia.
A representative sample from the population of a Novosibirsk district was examined using the 1988 WHO MONICA-MOPSY (847 women and 739 men aged 25-64 years) and the 2003 HAPIEE (1074 women and 576 men aged 45-64 years) programs. The health awareness and attitudes questionnaire was used.
The number of persons who considered perfectly healthy was minimal (2%) in the open Siberian population aged 25-64 years. The view of health in the women proved to be more pessimistic than that in the men. The fact that two thirds of the population could fall ill with a serious disease in the coming 5-10 years was accepted. Mainly the men took the view that modern medicine might prevent heart disease. The men were regularly examined 2 to 3 times more often than the women. The latter versus the men were less frequently inclined to stop work if they felt not quite well on-site, with the difference being more marked in old age groups. The majority of the study participants considered preventive examination to be useful for health. At the same time only a small portion of the population itself undergoes examination.
The changed socioeconomic situation in the country leads to the need to alter the established stereotypes of conscience and behavior of the population in health and to realize the need for personal responsibility for health.
PubMed ID
25823265 View in PubMed
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[Gender peculiarities of the risk of cardiovascular diseases in a population with symptoms of depression in Siberia (the WHO MONICA-psychosocial program)].

https://arctichealth.org/en/permalink/ahliterature290364
Source
Ter Arkh. 2017; 89(9):60-67
Publication Type
Journal Article
Author
V V Gafarov
E A Gromova
I V Gagulin
D O Panov
A V Gafarova
Author Affiliation
Research Institute of Therapy and Preventive Medicine, Novosibirsk, Russia; Interdepartmental Laboratory for Epidemiology of Cardiovascular Diseases, Novosibirsk, Russia.
Source
Ter Arkh. 2017; 89(9):60-67
Language
Russian
Publication Type
Journal Article
Keywords
Adult
Age Factors
Demography
Depression - diagnosis - epidemiology - physiopathology
Female
Humans
Male
Mass Screening - methods - statistics & numerical data
Middle Aged
Myocardial Infarction - epidemiology - psychology
Prevalence
Psychology
Risk factors
Sex Factors
Siberia - epidemiology
Socioeconomic Factors
Stroke - epidemiology - psychology
Abstract
To identify gender differences in the prevalence of depression in an open population of individuals aged 25-64 years and to evaluate its impact on the risk of cardiovascular diseases (CVD) in the population of Siberia.
A random representative sample of a 25-64-year-old Novosibirsk population (657 men and 689 women) was surveyed within the framework of the third screening of the WHO MONICA-psychosocial program in 1994. The screening program included sociodemographic data registration and depression detection. Over a 16-year study period, women had myocardial infarction (MI) in 15 cases and stroke in 35 cases and men had these conditions in 30 and 22 cases, respectively.
In the open 25-64-year-old population, depression was detected in 54.5% of the women and in 29% of the men; major depression was present in 11.8% of the women and 3.1% of the men (?2=66.724; ?=2; p=0.0001). The risk of MI in the depressed patients was higher in the women (hazard ratio (HR)=2.5) than in the men (HR=2); when social parameters and age are included in the model, only a trend towards the impact of depression on the risk of MI persisted in the women (HR=3.4; p>0.05) and the men were observed to have a 1.6-fold higher risk for MI. The greatest risk of MI was seen in the men (HR=6.8) and women (HR=6.3) at the age of 55-64 years, as well as in the men who had incomplete secondary or primary education (HR=3.2); in blue-collar workers (HR=6.7), in the men who were single (HR=3.6), divorced (HR=4.5), or widowed (HR=6). The risk of stroke in the depressed patients during a 16-year study period was greater in the men (HR=5.8) than in the women (HR=4.6); after adjusting for age and social gradient, the risk of stroke in the women was higher in both the population and those who were aged 55-64 years (HR=8.5 and 6.9, respectively) than that in the men (HR=4.2 and 3.1, respectively). Among the men, the risk of stroke was higher in those who had primary education (HR=8.8), were widowed (HR=8.4) or divorced (HR=2.7).
The women are much more susceptible to depression than are the men. The risk of MI with depression is higher in the women than in the men; at the same time, the risk of stroke is higher in the men than in the women. The picture is opposite in the older age group. The risk of CVD in the depressed men is exacerbated by a social gradient; these relationships have not been revealed in the women.
???? ????????????. ?????????? ????????? ???????? ?????????????????? ????????? ? ???????? ????????? ??? 25-64 ??? ? ??????? ?? ??????? ?? ???? ???????? ????????-?????????? ??????????? (???) ? ????????? ??????. ????????? ? ??????. ? ?????? III ????????? ????????? ??? 'MONICA-???????????????' ??????????? ????????? ???????????????? ??????? ????????? 25-64 ??? ???????????? ? 1994 ?. (657 ?????? ? 689 ??????). ????????? ????????????? ???????????? ???????? ??????????? ?????????-??????????????? ??????, ????????? ?????????. ?? 16-?????? ?????? ???????? 15 ? 35 ??????? ???????? ???????? (??) ? ???????? ? ?????? ? 30 ? 22 ?????? ? ??????. ??????????. ? ???????? ????????? ????????? 25-64 ???? ? 54,5% ?????? ? 29% ?????? ??????? ?????????, ?????? ? 11,8% ?????? ? 3,1% ?????? ??????? ????????? (?2=66,724; ?=2; ?=0,0001). ???? ???????? ?? ? ??? ? ?????????? ???? ? ?????? (????????? ?????? - HR=2,5), ??? ? ?????? (HR=2), ??? ????????? ? ?????? ?????????? ?????????? ? ???????? ??????????? ???? ????????? ??????? ????????? ?? ???? ???????? ?? ? ?????? (HR=3,4; p>0,05), ? ? ?????? ?????????? ?????????? ????? ???????? ?? ? 1,6 ????. ?????????? ???? ???????? ?? ?????? ? ?????? (HR=6,8) ? ?????? (HR=6,3) ? ???????? 55-64 ???, ? ????? ? ?????? ? ????????????? ??????? - ????????? ??????? ??????????? (HR=3,2); ? ??????? ???????? ??????????? ????? (HR=6,7), ? ??????, ??????? ??????? ?? ???? ?????? (HR=3,6), ???????? ? ??????? (HR=4,5) ??? ???????? (HR=6). ???? ???????? ???????? ? ??? ? ?????????? ? ??????? 16-??????? ??????? ???????? ???? ? ?????? (HR=5,8), ??? ? ?????? (HR=4,6); ? ?????? ???????? ?? ??????? ? ?????????? ???????? ? ?????? ???? ???????? ??? ???? ??? ? ?????????, ??? ? ? ???????? 55-64 ??? (HR=8,5 ? 6,9), ??? ? ?????? (HR=4,2 ? 3,1) ??????????????. ???? ???????? ???????? ??? ???? ? ?????? ? ????????? ??????? ??????????? (HR=8,8), ? ?????? ?????? (HR=8,4) ? ??????????? ?????? (HR=2,7). ??????????. ??????? ??????? ?????? ?????????? ?????????. ???? ???????? ?? ? ?????????? ???? ? ??????, ??? ? ??????; ? ?? ?? ????? ???? ???????? ???????? ???? ? ??????, ??? ? ??????. ? ??????? ?????????? ?????? ??????? ???????????????. ???? ???????? ??? ? ?????? ? ?????????? ???????????? ?????????? ??????????; ? ?????? ???????? ???????????? ?? ????????.
PubMed ID
29039832 View in PubMed
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[Genetic markers for trait anxiety as one of the risk factors for cardiovascular diseases (WHO-MONICA program, MONICA-psychosocial subprogram)].

https://arctichealth.org/en/permalink/ahliterature112653
Source
Ter Arkh. 2013;85(4):47-51
Publication Type
Article
Date
2013
Author
V V Gafarov
M I Voevoda
E A Gromova
V N Maksimov
I V Gagulin
N S Iudin
A V Gafarova
T M Mishakova
Source
Ter Arkh. 2013;85(4):47-51
Date
2013
Language
Russian
Publication Type
Article
Keywords
Adult
Anxiety - epidemiology - genetics - psychology
Cardiovascular Diseases - epidemiology - genetics - psychology
Dopamine Plasma Membrane Transport Proteins - genetics
Genetic markers
Genotype
Health Surveys
Humans
Male
Middle Aged
Personality - genetics
Polymorphism, Genetic - genetics
Prevalence
Receptors, Dopamine D4 - genetics
Risk
Risk factors
Siberia - epidemiology
World Health Organization
Abstract
To determine an association between trait anxiety (TA) and variable number tandem repeat (VNTR) polymorphisms in the DRD4 and DAT genes, as well as the prevalence of TA and the risk of cardiovascular diseases (CVD) in 25- to 64-year-old males with TA.
A representative sample of 25 to 64-year-old males (n = 2149) was examined within the framework of the WHO MONICA program, MONICA-psychosocial subprogram, in 1984, 1988, and 1994. All new-onset arterial hypertension (AH), myocardial infarction (MI), and stroke cases were registered throughout the follow-up study (1984-2008). Spielberger's test was used to estimate the level of TA. The Cox proportional regression model was applied to assess a relative risk.
The high level of anxiety (HLA) was 50.9% in the open population of 25 to 64-year-old males. The DRD4 genotype 4/6 and DAT genotype 9/9 were significantly associated with HLA. The latter increased the risk for CVD: it was maximal for AH and stroke within the first five years and for MI within 10 years.
HLA was significant in the Novosibirsk open population of 25 to 64-year-old males. It is substantially associated with certain VNTR polymorphisms in the DRD4 and DAT genes and considerably increases the risk of CVD.
PubMed ID
23808292 View in PubMed
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[Health education and motivation of the population with regard to health-related problems]

https://arctichealth.org/en/permalink/ahliterature73886
Source
Kardiologiia. 1989 Mar;29(3):74-7
Publication Type
Article
Date
Mar-1989
Author
I V Gagulin
V V Gafarov
N V Serova
M I Voevoda
Source
Kardiologiia. 1989 Mar;29(3):74-7
Date
Mar-1989
Language
Russian
Publication Type
Article
Keywords
Adult
Attitude to Health
Cardiovascular Diseases - prevention & control
English Abstract
Female
Health education
Humans
Male
Middle Aged
Motivation
Questionnaires
Self Concept
Siberia
Abstract
A random representative population sample of 1493 individuals (753 males and 740 females), aged 25 to 64 years, was investigated, using standard epidemiologic procedures as part of a program, studying, trends of development and control of cardiovascular diseases. Population awareness of health status and attitudes to preventive efforts and harmful habits were assessed with reference to age and sex. Preventive screenings were considered to be useful by 83% of the males and 88% of the females; these rates were however smaller for young individuals. In groups of older individuals, health self-assessments were less adequate, while willingness to abandon bad habits increased, particularly so in the females, as compared to the males.
PubMed ID
2733343 View in PubMed
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22 records – page 1 of 3.