Skip header and navigation

Refine By

40 records – page 1 of 4.

[Acute intermittent porphyria increases the risk of liver cancer. Early diagnosis of the cancer and varying surgery may improve the prognosis]

https://arctichealth.org/en/permalink/ahliterature21547
Source
Lakartidningen. 1998 Jun 24;95(26-27):3043-4
Publication Type
Article
Date
Jun-24-1998
Author
C. Andersson
L. Bjersing
F. Lithner
Author Affiliation
Medicinska kliniken, Norrlands Universitetssjukhus, Umeå.
Source
Lakartidningen. 1998 Jun 24;95(26-27):3043-4
Date
Jun-24-1998
Language
Swedish
Publication Type
Article
Keywords
Female
Humans
Liver Neoplasms - diagnosis - etiology - mortality - surgery
Male
Porphyria, Acute Intermittent - complications - mortality
Prognosis
Risk factors
Sweden - epidemiology
PubMed ID
9679414 View in PubMed
Less detail

[Acute intermittent porphyria. Risk of secondary hypertension--needs follow-up!].

https://arctichealth.org/en/permalink/ahliterature215335
Source
Lakartidningen. 1995 Apr 19;92(16):1685-6
Publication Type
Article
Date
Apr-19-1995

Amputations in diabetic patients in Gotland and Umeå counties 1971-1980.

https://arctichealth.org/en/permalink/ahliterature48894
Source
Acta Med Scand Suppl. 1984;687:89-93
Publication Type
Article
Date
1984
Author
P. Lindegård
B. Jonsson
F. Lithner
Source
Acta Med Scand Suppl. 1984;687:89-93
Date
1984
Language
English
Publication Type
Article
Keywords
Adult
Amputation
Diabetes Complications
Diabetes Mellitus - mortality
Female
Gangrene
Humans
Leg - pathology - surgery
Male
Middle Aged
Sweden
Abstract
In two counties of Sweden, Gotland and Umeå, lower leg or thigh amputations were performed during 1971-1980 in 111 and 71 diabetic patients, respectively. These figures correspond to 20.5 and 6.5 per 100 000 inhabitants and year, respectively. The corresponding incidence for Umeå city and the rural area surrounding Umeå was 3.1 and 13.8/100 000 inhabitants and year, respectively. The lower frequency of amputations in Umeå was probably the consequence of a restricted period of systematic search for early signs of gangrene, as a part of a research program, but other factors could also be of importance and these are discussed. The death rate of the patients was high in both series, after 2 years only about one third of the patients were still alive.
PubMed ID
6591765 View in PubMed
Less detail

Amputations in diabetics and nondiabetics in Umeå county 1971-1977.

https://arctichealth.org/en/permalink/ahliterature48893
Source
Acta Med Scand Suppl. 1984;687:95-100
Publication Type
Article
Date
1984
Author
B. Borssén
F. Lithner
Source
Acta Med Scand Suppl. 1984;687:95-100
Date
1984
Language
English
Publication Type
Article
Keywords
Aged
Amputation
Diabetic Angiopathies - rehabilitation - surgery
Female
Gangrene
Humans
Leg - pathology - surgery
Length of Stay
Male
Middle Aged
Prognosis
Reoperation
Retrospective Studies
Sweden
Wound Healing
Abstract
A consecutive series of 95 unselected patients submitted to amputation of the lower leg (59%) or at the thigh (41%) during 1971-1977 are the material of this retrospective study. Fifty-three were diabetic and 42 nondiabetic, the mean age was 77.2 and 73.1 years, respectively. There were no differences between diabetics and nondiabetics concerning age, lower leg/thigh amputations, postoperative healing, rehabilitation using prosthesis or subsequent amputation of the second leg.
PubMed ID
6591767 View in PubMed
Less detail

Assessment of autonomic nerve function in acute intermittent porphyria; a study based on spectral analysis of heart rate variability.

https://arctichealth.org/en/permalink/ahliterature211401
Source
J Intern Med. 1996 Aug;240(2):73-9
Publication Type
Article
Date
Aug-1996
Author
H. Blom
C. Andersson
B O Olofsson
P. Bjerle
U. Wiklund
F. Lithner
Author Affiliation
Department of Internal Medicine, Umeå University Hospital, Sweden.
Source
J Intern Med. 1996 Aug;240(2):73-9
Date
Aug-1996
Language
English
Publication Type
Article
Keywords
Adult
Aged
Autonomic Nervous System - physiopathology
Case-Control Studies
Cross-Sectional Studies
Female
Heart rate
Humans
Male
Middle Aged
Porphyria, Acute Intermittent - physiopathology
Signal Processing, Computer-Assisted
Abstract
To assess the function of the autonomic nervous system in patients with acute intermittent porphyria by spectral analysis of the heart rate variability.
A cross-sectional case-control study.
Patients were examined at the Primary Health Care Centre, Arjeplog and at Umeå University Hospital, where the controls were also examined.
Twenty-three patients with acute intermittent porphyria verified by DNA analysis and 92 healthy controls were included.
The mid-frequency band power after tilting was used to evaluate sympathetic function, and the high frequency band power during controlled breathing at 12 breaths min-1 and the mid-frequency band power during controlled deep breathing at 6 breaths min-1 were used to evaluate parasympathetic function.
There was no evidence of sympathetic dysfunction in the patients. The mid-frequency band power during controlled deep breathing at 6 breaths min-1 was significantly (P = 0.02) lower in the patient group.
Our findings indicate a parasympathetic dysfunction in patients with acute intermittent porphyria. This may be causally related to sudden cardiac death and the life-threatening arrhythmias which have been observed in this disorder.
PubMed ID
8810932 View in PubMed
Less detail

The association of fibrinolysis and hyperlipidaemia with quantitative sensory tests in an epidemiological study of Swedish type 1 diabetic patients.

https://arctichealth.org/en/permalink/ahliterature48376
Source
Diabet Med. 1995 Jul;12(7):590-4
Publication Type
Article
Date
Jul-1995
Author
F. Lithner
T. Bergenheim
B. Borssén
G. Dahlén
T K Nilsson
Author Affiliation
Department of Medicine, University Hospital of Umeå, Sweden.
Source
Diabet Med. 1995 Jul;12(7):590-4
Date
Jul-1995
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Analysis of Variance
Cholesterol - blood
Comparative Study
Diabetes Mellitus, Type 1 - blood - epidemiology - physiopathology
Diabetic Neuropathies - epidemiology - physiopathology
Electric Stimulation
Female
Fibrinolysis
Hemoglobin A, Glycosylated - analysis
Humans
Hyperlipidemia - epidemiology
Lipoproteins, HDL Cholesterol - blood
Male
Middle Aged
Plasminogen Activator Inhibitor 1 - blood
Regression Analysis
Research Support, Non-U.S. Gov't
Risk factors
Sensory Thresholds
Sweden - epidemiology
Tissue Plasminogen Activator - blood
Triglycerides - blood
Vibration
Abstract
Serum levels of cholesterol, HDL-cholesterol, triglycerides, lipoprotein Lp(a), and the fibrinolysis factors tPA (tissue plasminogen activator) and PAI-1 activity (plasminogen activator inhibitor) were compared with sensory thresholds for vibration, electrical current perception, and pain in a population-based study comprising 239 patients with diabetes mellitus Type 1, aged 15-50 years. Univariate regression analyses (n = 180) showed significant correlations between elevated sensory thresholds and age, duration of diabetes, serum cholesterol and triglycerides, and HbA1c. In multivariate regression analysis, age, duration of diabetes, height, and serum triglycerides showed significant independent associations with five or six of the six measured sensory threshold variables. In addition there was a significant association between increased thresholds for vibration and Lp(a) levels. Thus, increased sensory thresholds for vibration, current perception, and pain in patients with Type 1 diabetes are associated with increased serum triglyceride levels, and Lp(a) levels are associated with increased threshold for vibration. Fibrinolytic activity is unrelated to these measures of nerve function in Type 1 diabetic patients.
PubMed ID
7554780 View in PubMed
Less detail

The association of hyperlipidemia with retinopathy in diabetic patients aged 15-50 years in the county of Umeå.

https://arctichealth.org/en/permalink/ahliterature47926
Source
Acta Ophthalmol Scand. 1999 Oct;77(5):585-91
Publication Type
Article
Date
Oct-1999
Author
L I Larsson
A. Alm
F. Lithner
G. Dahlén
R. Bergström
Author Affiliation
Department of Ophthalmology, Uppsala University Hospital, Sweden.
Source
Acta Ophthalmol Scand. 1999 Oct;77(5):585-91
Date
Oct-1999
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Cholesterol - blood
Diabetes Mellitus, Type 1
Diabetic Retinopathy - complications - physiopathology
Female
Humans
Hyperlipidemia - blood - complications
Lipoprotein(a) - blood
Lipoproteins, HDL Cholesterol - blood
Male
Middle Aged
Research Support, Non-U.S. Gov't
Severity of Illness Index
Triglycerides - blood
Abstract
PURPOSE: To study possible associations between serum lipid levels and degree of retinopathy in a population-based study on a specific age-group of patients with diabetes mellitus in the county of Umeå, Sweden. METHODS: All patients with diabetes mellitus aged 15-50 years living in the county of Umeå were invited to the study. The participating subjects had a standard clinical examination and an eye examination performed. Seven-field stereoscopic photographs were taken of each eye, and the photos were sent to Grading Center, Hammersmith Hospital, London, U.K. for grading of the retinopathy. Blood samples were drawn for analysis of lipoprotein(a), high density lipoprotein (HDL) cholesterol, cholesterol and triglycerides. Univariate and multivariate statistical analyses were performed. RESULTS: In the present study only patients with type 1 diabetes mellitus were included, and 285 of the invited 308 diabetic subjects (93%) took part. When univariate analysis was applied we found statistically significant associations between higher lipoprotein(a) levels, higher triglyceride levels, higher cholesterol levels, lower HDL cholesterol/total cholesterol ratios and increasing severeness of retinopathy. However, in the multivariate analysis triglyceride levels lost their importance while all other significant associations were still present. CONCLUSION: Associations were found between higher levels of serum total cholesterol, declining ratios of high density lipoprotein (HDL) cholesterol/total cholesterol, higher levels of serum lipoprotein(a) and more severe retinopathy in diabetes mellitus type 1. No such association was found between serum triglycerides and degree of retinopathy.
PubMed ID
10551307 View in PubMed
Less detail

Clinical profiles of cerebrovascular disorders in a population-based patient sample.

https://arctichealth.org/en/permalink/ahliterature48824
Source
J Chronic Dis. 1987;40(11):1025-32
Publication Type
Article
Date
1987
Author
S. Eriksson
K. Asplund
E. Hägg
F. Lithner
T. Strand
P O Wester
Author Affiliation
Department of Medicine, University Hospital, Umeå, Sweden.
Source
J Chronic Dis. 1987;40(11):1025-32
Date
1987
Language
English
Publication Type
Article
Keywords
Age Factors
Aged
Aged, 80 and over
Cerebral Hemorrhage - diagnosis
Cerebral Infarction - diagnosis
Cerebrovascular Disorders - diagnosis - epidemiology
Comparative Study
Female
Humans
Intracranial Embolism and Thrombosis - diagnosis
Ischemic Attack, Transient - diagnosis
Male
Middle Aged
Prospective Studies
Research Support, Non-U.S. Gov't
Risk factors
Sex Factors
Sweden
Abstract
Clinical features of different types of stroke were investigated in a sample of 409 patients representative of all cases admitted for acute stroke, except subarachnoidal hemorrhages, within a well defined population. A specific cerebrovascular diagnosis was obtained by detailed clinical investigation, including CT scan. In people greater than 50 years old, men/women risk for stroke was estimated to be 1.40:1. The risk was higher in men up to the age of 80; above this age similar risk for the two genders was observed. Eleven per cent had intracerebral hemorrhage, 13% TIA, 51% non-embolic and 25% embolic brain infarction. In all diagnostic categories there were similar proportions of patients who had a history of hypertension and previous stroke, neither did hemoglobin and hematocrit levels differ between the different stroke disorders. TIA preceded intracerebral hemorrhage in 11% and brain infarction in 15-20%. As opposed to patients with ischemic lesions, subjects with intracerebral hemorrhage had higher systolic blood pressure levels and more severe symptoms on admission to hospital. Ischemic stroke was associated with male predominance, different ischemic manifestations of heart diseases and diabetes.
PubMed ID
3654902 View in PubMed
Less detail

[Decreased length of stay for pregnant diabetics as the result of the special diabetic midwife]

https://arctichealth.org/en/permalink/ahliterature65551
Source
Lakartidningen. 1986 Mar 26;83(13):1178-80
Publication Type
Article
Date
Mar-26-1986
Author
A. Brant
D E Wiklund
F. Lithner
Source
Lakartidningen. 1986 Mar 26;83(13):1178-80
Date
Mar-26-1986
Language
Swedish
Publication Type
Article
Keywords
Female
Humans
Length of Stay
Nurse Midwives
Pregnancy
Pregnancy in diabetics - therapy
Sweden
PubMed ID
3702550 View in PubMed
Less detail

40 records – page 1 of 4.