This study aims to study physiological stress indicators in relation to prevalence of building-related symptoms (BRS) among teachers employed in three selected schools in Copenhagen. Three hypotheses were studied: (i) Perceived psychosocial work environment was associated with BRS; (ii) Perceived psychosocial work environment (job strain) was associated with physiological strain; (iii) BRS was associated with physiological strain. We found a tendency among women of an association between job strain and being BRS positive. Also an association between job strain and physiological strain was observed among women. Being BRS positive was not associated with single physiological stress indicators with the exception of a higher level free testosterone in serum among BRS-positive women.
Including physiological stress indicators may be a supplementary measure to questionnaires when studying the association between the psychosocial work environment and building-related symptoms (BRS). In this study, job strain was associated with physiological strain among women. Being BRS positive was not associated with single physiological stress indicators with the exception of a higher level free testosterone in serum among BRS-positive women. This study should be regarded as a preliminary study because of its small number of participants.
Former studies on the association between snoring and cardiovascular disease (CVD) have only partly taken established CVD risk factors into consideration. In the Copenhagen Male Study, 3323 men aged 54-74 years were classified according to self-reported snoring habits. Eleven CVD risk factors were examined. The prevalence of snoring decreased with age, with a 50% higher frequency of snorers in the youngest quintile than in the oldest, p
In The Copenhagen Male Study, an epidemiological study comprising 3,387 men aged 53 to 75 years, 3,303 men with valid questionnaire answers to questions on occupational organic solvents exposure, four cerebral symptoms and current work status were examined. Two hundred and ninety-five men had been occupationally exposed to mixed organic solvents for a period of five years or more. Among the exposed persons, 178 had retired, while 117 were still gainfully employed. The exposed men in both groups had highly significantly more complaints of decreased concentration and defective memory. Among the exposed retired men a higher prevalence of headache was found. Among the exposed men who were still employed a trend towards a higher prevalence of vertigo was found. This study was conducted within a cardiovascular study with no focus on the relationship between organic solvent exposure and cerebral symptoms, a design reducing the risk of overreporting. If overreporting was responsible for the differences found between solvent exposed and unexposed a similar pattern for reporting of acute and chronic symptoms should be expected. This was not the case. Our results support the hypothesis, that occupational exposure to organic solvents for a period of five years or more increases the risk of developing persistent defective memory and decrease in concentration.
In a cardiovascular survey of 928 men and women aged exactly 30, 40, 50 & 60 years, a correlation between serum cholesterol, cholesterol/HDL-ratio and arterial blood pressure was found. This correlation was indirectly caused by mutual correlations to relative weight and age as a final result found after multiple rank correlation analysis in each sex. HDL was not correlated to arterial blood pressure at all.
In a two year experimental project, 38 persons were referred to clinical examination at a clinic for occupational medicine. Admission was based upon suspicion of health damage caused by environmental factors outside the occupational setting. Twentyseven persons were suspected of indoor exposure with unspecified dust as the dominating factor. In the general environment, suspected exposure from polluted soil was the main reason for admission of 11 patients. In 22 cases, a causal relation between complaints and exposure to environmental factors was considered likely and recommendations to eliminate exposure or to effectuate further investigations of exposure were made. It is concluded that there is a need for an arrangement whereby patients can be examined by doctors experienced in assessing relations between exposure from environmental factors and disease. Since only few patients are expected, the examinations can be carried out in clinics for occupational medicine within existing resources.
OBJECTIVE. Based on a meta-analysis, it was recently stated that there is no association between coffee consumption and the risk of coronary heart disease. Why then, have studies on the issue shown quite variable results? DESIGN SETTING AND SUBJECTS. A prospective study was performed in the Copenhagen Male Study on 2975 men (53-74 years) without cardiovascular disease at baseline in 1985/1986. They were classified according to self-reported consumption of filter coffee. Some 147 men (5%) were coffee abstainers. Potential confounders were alcohol use, physical activity, smoking, serum cotinine, serum lipids, serum selenium, body mass index, blood pressure, Lewis blood group, hypertension, non-insulin-dependent diabetes mellitus and social class. MAIN OUTCOME MEASURES. The incidence of ischaemic heart disease (IHD) 1985/86-1991. RESULTS. Some 184 men had a first IHD event. There was no significant difference between those consuming 1-4, 5-8 or > or = 9 cups per day after controlling for confounders (P-value of trend test: 0.14). The crude incidence rates were 6.8, 6.7 and 4.6%, respectively; the adjusted rates were 6.8, 6.7 and 4.0%, respectively. Coffee consumption was significantly (P
Recent studies have reported higher plasma estradiol levels in male survivors of acute myocardial infarction. This finding has raised the possibility that hyperestrogenemia may consitiute a separate coronary risk factor. In 443 men, aged 30, 40, 50, and 60, we assessed the relationship between plasma levels of estradiol, testosterone, and testosterone-binding globulin and coronary risk factors: fasting plasma concentrations of triglyceride, cholesterol, and high-density lipoprotein, blood pressure, and smoking and leisure-time physical activity patterns. Plasma estradiol concentrations were found to correlate significantly with body weight. After adjustment for this association, we found that the mean plasma estradiol concentration still was significantly higher in smokers than in nonsmokers. No other correlation could be estabilished between plasma hormone levels and coronary risk factors. The relative hyperestrogenemia reported in men with previous myocardial infarction may be due to an effect of smoking but may also reflect the relationship between body weight and plasma estradiol levels. Future studies should consider the demonstrated association between plasma estrogen levels and smoking.