Skip header and navigation

2 records – page 1 of 1.

Investigation and management of cervical intraepithelial neoplasia in Canadian Inuit: enhancing access to care.

https://arctichealth.org/en/permalink/ahliterature4093
Source
Arctic Med Res. 1995;54 Suppl 1:117-21
Publication Type
Article
Date
1995
Author
B. Martin
W. Smith
P. Orr
F. Guijon
Author Affiliation
Department of Community Health Sciences, University of Manitoba, Winnipeg, Canada.
Source
Arctic Med Res. 1995;54 Suppl 1:117-21
Date
1995
Language
English
Publication Type
Article
Keywords
Arctic regions - ethnology
Canada - epidemiology
Carcinoma in Situ - ethnology - prevention & control
Colposcopy
Delivery of Health Care
Electrosurgery
Female
Humans
Inuits
Uterine Cervical Neoplasms - ethnology - prevention & control
Abstract
Cervical intraepithelial neoplasia (CIN) is a major cause of morbidity among Circumpolar women. Cervical cancer comprised 15% of all cancers in Canadian Inuit women from 1969-1988. The age standardized incidence for invasive cervical cancer in Canadian Inuit women is 3.1 times the rate in the general Canadian population. Management of CIN in women of remote Arctic regions has traditionally required multiple visits to specialized medical centres for diagnosis, therapy and follow-up. Such centralized care requires separation of women from their families, resulting in significant medical, emotional and economic costs for the patient, her family and community. In the Canadian Central Arctic, a program for the diagnosis and therapy of CIN has been established using colposcopy with loop electrosurgery, performed by a trained local family practitioner and visiting gynecologist. Early program evaluation has indicated reduction in medical expenditures due to travel costs, minimal procedure-related morbidity and discomfort, and improved patient satisfaction associated with reduced separation from family and community. It is hoped that the program design, which harnesses technology in order to provide improved care closer to home, will be applicable to other Circumpolar regions.
PubMed ID
7639897 View in PubMed
Less detail

Vaginal microbial flora as a cofactor in the pathogenesis of uterine cervical intraepithelial neoplasia.

https://arctichealth.org/en/permalink/ahliterature224292
Source
Int J Gynaecol Obstet. 1992 Mar;37(3):185-91
Publication Type
Article
Date
Mar-1992
Author
F. Guijon
M. Paraskevas
F. Rand
E. Heywood
R. Brunham
P. McNicol
Author Affiliation
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Manitoba, Winnipeg, Canada.
Source
Int J Gynaecol Obstet. 1992 Mar;37(3):185-91
Date
Mar-1992
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Case-Control Studies
Colposcopy
Female
Humans
Infection - complications - epidemiology - microbiology
Manitoba - epidemiology
Mycoplasma Infections - complications - epidemiology - microbiology
Papillomaviridae
Prevalence
Risk factors
Sexual Behavior
Tumor Virus Infections - complications - epidemiology - microbiology
Uterine Cervical Neoplasms - epidemiology - etiology
Vaginal Diseases - complications - epidemiology - microbiology
Vaginal Smears
Abstract
The vaginal microbial flora of 106 women with histopathologically confirmed cervical intraepithelial neoplasia and 79 women without disease, was evaluated for Gardnerella vaginalis, Trichomonas vaginalis, Candida albicans and other yeasts. Flora morphology was assessed by gram staining of secretions. Cervical cultures were examined for Herpes Simplex virus, Cytomegalovirus and Neisseria gonorrhoeae. Chlamydia trachomatis antigens in cervical secretions were detected by enzyme immunoassay. Human Papillomavirus was identified by koilocytosis in cytologic or histopathologic specimens. Human Papillomavirus infection (P less than 0.00001), vaginal infection with Mycoplasma hominis (P = 0.012) and abnormal vaginal flora (P = 0.006) were significantly associated with CIN, suggesting that CIN may be promoted by vaginal microorganisms in conjunction with human papillomavirus cervical infection.
PubMed ID
1351005 View in PubMed
Less detail