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Prevalence and prognostic significance of malnutrition in patients with cancers of the head and neck.

https://arctichealth.org/en/permalink/ahliterature299403
Source
Clin Nutr. 2019 Apr 04; :
Publication Type
Journal Article
Date
Apr-04-2019
Author
Catherine Kubrak
Lisa Martin
Leah Gramlich
Rufus Scrimger
Naresh Jha
Brock Debenham
Neil Chua
John Walker
Vickie E Baracos
Author Affiliation
Department of Oncology, Division of Palliative Care Medicine, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, T6G 1Z2, Canada.
Source
Clin Nutr. 2019 Apr 04; :
Date
Apr-04-2019
Language
English
Publication Type
Journal Article
Abstract
Head and neck cancer (HNC) are at high nutritional risk; however the prevalence and severity of malnutrition in contemporary patients with HNC are unclear. Diagnostic criteria for cancer-associated weight loss grading (WLG) (Grades 0 to 4) [1] have been validated and are recommended in oncology nutrition clinical practice guidelines [2-3]. The aim was to determine the prevalence using WLG in HNC patients and determine the extent to which reduced dietary intake (DI) explained variation of WLG.
A population-based cohort of HNC patients (N = 1756) in northern Alberta, Canada included consecutive new patients, 2004-2016. At referral to the regional cancer center weight history and DI categories were collected. Multinomial logistic regression (MLR) identified predictors of weight loss (WL) severity. Overall survival (OS) in relation to WL Grade and DI was determined by multivariable Cox proportional hazard.
WL was absent in 42.9% and the remainder had Grade 1 (18%), Grade 2 (14.7%), Grade 3 (15.9%) and Grade 4 (8.5%) WL. Independent predictors of WLG in adjusted MLR model, included stage (P 
PubMed ID
31000341 View in PubMed
Less detail

Prevalence and prognostic significance of malnutrition in patients with cancers of the head and neck.

https://arctichealth.org/en/permalink/ahliterature309568
Source
Clin Nutr. 2020 03; 39(3):901-909
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
03-2020
Author
Catherine Kubrak
Lisa Martin
Leah Gramlich
Rufus Scrimger
Naresh Jha
Brock Debenham
Neil Chua
John Walker
Vickie E Baracos
Author Affiliation
Department of Oncology, Division of Palliative Care Medicine, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, T6G 1Z2, Canada.
Source
Clin Nutr. 2020 03; 39(3):901-909
Date
03-2020
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Abstract
Head and neck cancer (HNC) are at high nutritional risk; however the prevalence and severity of malnutrition in contemporary patients with HNC are unclear. Diagnostic criteria for cancer-associated weight loss grading (WLG) (Grades 0 to 4) [1] have been validated and are recommended in oncology nutrition clinical practice guidelines [2-3]. The aim was to determine the prevalence using WLG in HNC patients and determine the extent to which reduced dietary intake (DI) explained variation of WLG.
A population-based cohort of HNC patients (N = 1756) in northern Alberta, Canada included consecutive new patients, 2004-2016. At referral to the regional cancer center weight history and DI categories were collected. Multinomial logistic regression (MLR) identified predictors of weight loss (WL) severity. Overall survival (OS) in relation to WL Grade and DI was determined by multivariable Cox proportional hazard.
WL was absent in 42.9% and the remainder had Grade 1 (18%), Grade 2 (14.7%), Grade 3 (15.9%) and Grade 4 (8.5%) WL. Independent predictors of WLG in adjusted MLR model, included stage (P 
PubMed ID
31000341 View in PubMed
Less detail