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11 records – page 1 of 2.

Anthropometry at the time of diagnosis in Danish children with inflammatory bowel disease.

https://arctichealth.org/en/permalink/ahliterature29341
Source
Acta Paediatr. 2005 Nov;94(11):1682-3
Publication Type
Article
Date
Nov-2005
Author
Anders Paerregaard
Frederikke Uldall Urne
Author Affiliation
Department of Paediatrics, Hvidovre University Hospital, Hvidovre, Denmark. anders.paerregaard@hh.hosp.dk
Source
Acta Paediatr. 2005 Nov;94(11):1682-3
Date
Nov-2005
Language
English
Publication Type
Article
Keywords
Adolescent
Body Height
Body mass index
Child
Child Nutrition Disorders - epidemiology
Child, Preschool
Colitis, Ulcerative - epidemiology
Crohn Disease - epidemiology
Denmark - epidemiology
Growth
Humans
Infant
Abstract
All patients below 15 y of age living in the eastern part of Denmark with a diagnosis of inflammatory bowel disease (IBD) during the period 1998-2000 were identified (n=94) and anthropometrical data at the time of diagnosis were evaluated.CONCLUSION: The height-for-age and the BMI-for-age, as evaluated by z-scores, of children with ulcerative colitis (UC) did not differ from those of normal Danish children, but Crohn's disease (CD) children had significantly lower height and BMI values, both when compared to normal children and children with UC. In contrast to UC, CD is frequently complicated by malnutrition and growth retardation at the time of diagnosis.
PubMed ID
16303711 View in PubMed
Less detail

[Chronic inflammatory bowel disease in children. An epidemiological study from eastern Denmark 1998-2000]

https://arctichealth.org/en/permalink/ahliterature31179
Source
Ugeskr Laeger. 2002 Dec 2;164(49):5810-4
Publication Type
Article
Date
Dec-2-2002
Author
Frederikke Uldall Urne
Anders Paerregaard
Author Affiliation
H:S Hvidovre Hospital, børneafdelingen.
Source
Ugeskr Laeger. 2002 Dec 2;164(49):5810-4
Date
Dec-2-2002
Language
Danish
Publication Type
Article
Keywords
Adolescent
Child
Child, Preschool
Cohort Studies
Colitis - epidemiology
Colitis, Ulcerative - epidemiology
Crohn Disease - epidemiology
Denmark - epidemiology
English Abstract
Female
Humans
Incidence
Male
Prevalence
Retrospective Studies
Abstract
INTRODUCTION: The purpose of this retrospective study was to investigate the epidemiology and anthropometrical status in children and adolescents with chronic inflammatory bowel disease in Denmark during the period 1998-2000. MATERIAL AND METHODS: Patients from the eastern part of Denmark below 15 years of age were included. The study covered 43% of the total pediatric population (
PubMed ID
12523226 View in PubMed
Less detail

[Detection of rotavirus infection in Danish children.]

https://arctichealth.org/en/permalink/ahliterature96271
Source
Ugeskr Laeger. 2010 Jul 26;172(30):2116-2120
Publication Type
Article
Date
Jul-26-2010
Author
Nete Munk Nielsen
Anders Pærregaard
Thea Kølsen Fischer
Author Affiliation
Afdeling for Epidemiologisk Forskning, Statens Serum Institut, 2300 København S. NMN@ssi.dk.
Source
Ugeskr Laeger. 2010 Jul 26;172(30):2116-2120
Date
Jul-26-2010
Language
Danish
Publication Type
Article
Abstract
INTRODUCTION: Rotavirus (RV) is the most frequent causative agent of severe diarrhoea in infants and young children worldwide, also in Denmark. However, the actual number of diagnosed RV cases among Danish children is unknown. If a new RV-vaccine is to be introduced in Denmark, updated data on RV disease burden is important and the validity of potential surveillance systems needs to be explored. MATERIAL AND METHODS: We established a nation-wide database on all children below the age of 5 years who had a RV-positive sample detected from 2001 to 2004 at one of the 13 laboratories in Denmark performing RV diagnostics. Hospital discharge diagnoses among the RV-positive children were retrieved from the Danish Hospital Discharge Register (DHDR). RESULTS: A total of 1,789 children
PubMed ID
20654279 View in PubMed
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Environmental factors and risk of developing paediatric inflammatory bowel disease -- a population based study 2007-2009.

https://arctichealth.org/en/permalink/ahliterature122966
Source
J Crohns Colitis. 2013 Feb;7(1):79-88
Publication Type
Article
Date
Feb-2013

Infliximab dependency in a national cohort of children with Crohn's disease.

https://arctichealth.org/en/permalink/ahliterature29289
Source
J Pediatr Gastroenterol Nutr. 2006 Jan;42(1):40-5
Publication Type
Article
Date
Jan-2006
Author
Vibeke Wewer
Lene Riis
Ida Vind
Steffen Husby
Pia Munkholm
Anders Paerregaard
Author Affiliation
Department of Pediatrics and Medical Gastroenterology, H:S Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark. vibeke.wewer@hh.hosp.dk
Source
J Pediatr Gastroenterol Nutr. 2006 Jan;42(1):40-5
Date
Jan-2006
Language
English
Publication Type
Article
Abstract
AIM: The aim was to evaluate the pattern of responsiveness and to monitor side effects of episodic administration of infliximab in children with active Crohn's disease (CD) treated in Denmark from 1999 to 2003. MATERIAL AND METHODS: The National Danish Crohn Colitis Database of infliximab was used to identify all Danish CD patients treated at pediatric departments with infliximab. The clinical outcome was assessed by pattern recognition of the disease course 30 days after the first infliximab infusion and 90 days after intended end of treatment. RESULTS: During a 3 year period, infliximab was given to 24 CD patients (9 male/15 female) aged median 15.4 (range 9.8-18.6) years with a median disease duration of 26 (range 0.7-93) months and a median number of infusions of 6 (range 2-11). Five milligrams of infliximab per kilogram infusions were given intravenously. Immediate response was as follows: 8 (33%) patients achieved complete response (CR), 10 (42%) partial response (PR), and 6 (25%) no response (NR). Long-term response was as follows: 7 (29%) patients achieved prolonged response (PRO), defined as maintenance of CR or PR, 10 (42%) were infliximab dependent (ID), defined as relapse of symptoms requiring reinfusions of infliximab to regain CR or PR, and 6 (25%) had NR. Six (25%) patients needed surgery during or after treatment with infliximab. Side effects were seen in four (17%) patients. No serious events were noted. CONCLUSION: Seventy-one percent of the children appeared to benefit (PRO or ID) from infliximab treatment with minor side effects when given episodically. Among these patients, two response patterns were recognized: PRO after ending infliximab treatment (29%) or dependency on reinfusions of infliximab (42%).
PubMed ID
16385252 View in PubMed
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A new mutation causing autosomal dominant periodic fever syndrome in a Danish family.

https://arctichealth.org/en/permalink/ahliterature13915
Source
J Pediatr. 2003 Feb;142(2):191-3
Publication Type
Article
Date
Feb-2003
Author
Heike Weyhreter
Marianne Schwartz
Tim D Kristensen
Niels H Valerius
Anders Paerregaard
Author Affiliation
Department of Paediatrics 531, H:S Hvidovre Hospital, Copenhagen, Denmark.
Source
J Pediatr. 2003 Feb;142(2):191-3
Date
Feb-2003
Language
English
Publication Type
Article
Keywords
Adult
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Antigens, CD - genetics
Biological Response Modifiers - therapeutic use
Case-Control Studies
Child
DNA Mutational Analysis
Denmark - epidemiology
Familial Mediterranean Fever - drug therapy - epidemiology - genetics
Female
Genes, Dominant - genetics
Humans
Immunoglobulin G - therapeutic use
Infant
Male
Middle Aged
Mutation - genetics
Pedigree
Polymerase Chain Reaction
Receptors, Tumor Necrosis Factor - genetics - therapeutic use
Receptors, Tumor Necrosis Factor, Type I
Restriction Mapping
Abstract
We describe four members in a family of 8 individuals over 3 generations with the autosomal dominant inherited periodic fever syndrome tumor necrosis factor receptor-associated periodic syndrome (TRAPS). The patients had recurrent episodes of fever, abdominal pain, arthritis, and rash. We examined the gene coding for the tumor necrosis factor receptor TNFRSF1A in all first-degree family members. In all 4 symptomatic members of the family, a hitherto undescribed mutation C98Y (380G-->A) in the TNFRSF1A gene was identified. In contrast, this mutation was not found in the 4 family members reported to be healthy nor in 50 normal control patients. The youngest member of the family, a 2-year-old boy, was treated successfully with etanercept.
Notes
Comment In: J Pediatr. 2003 Feb;142(2):99-10112584526
PubMed ID
12584543 View in PubMed
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Paediatric inflammatory bowel disease during a 44-year period in Copenhagen County: occurrence, course and prognosis--a population-based study from the Danish Crohn Colitis Database.

https://arctichealth.org/en/permalink/ahliterature149844
Source
Eur J Gastroenterol Hepatol. 2009 Nov;21(11):1291-301
Publication Type
Article
Date
Nov-2009
Author
Christian Jakobsen
Anders Paerregaard
Pia Munkholm
Vibeke Wewer
Author Affiliation
Department of Paediatrics, Hvidovre University Hospital, Kettegaard Alle 30, Hvidovre, Copenhagen, Denmark. christian.jakobsen@hvh.regionh.dk
Source
Eur J Gastroenterol Hepatol. 2009 Nov;21(11):1291-301
Date
Nov-2009
Language
English
Publication Type
Article
Keywords
Adolescent
Child
Colectomy - trends - utilization
Colitis, Ulcerative - complications - epidemiology - pathology - therapy
Colorectal Neoplasms - epidemiology - etiology
Crohn Disease - epidemiology - pathology - therapy
Denmark - epidemiology
Epidemiologic Methods
Female
Glucocorticoids - therapeutic use
Humans
Inflammatory Bowel Diseases - complications - epidemiology - pathology - therapy
Male
Prognosis
Abstract
To describe the development in incidence, disease localization, activity, surgery and prognosis in two Danish paediatric population-based inflammatory bowel disease (IBD) cohorts comparing the time periods 1962-1987 (period I) and 1998-2006 (period II).
Incident IBD patients below 15 years of age were included. Disease localization was classified according to the Montreal classification for ulcerative colitis (UC) patients and into small bowel, large bowel and small and large bowel combined for Crohn's disease (CD) patients. Disease activity and surgery in the first 2 years after diagnosis were assessed. Standardized cancer incidence rates and standardized mortality rates were calculated.
One hundred and nineteen IBD patients (77 UC and 42 CD) were included. Comparing periods II and I, the incidence rate ratios were 0.81 [95% confidence interval (CI): 0.5-1.4] and 15.6 (95% CI: 7.5-32.7) in UC and CD, respectively. The number of UC patients with extensive disease (E3) increased from period I to II (46.7 vs. 94.1%, P
PubMed ID
19581873 View in PubMed
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Steroid dependency and pediatric inflammatory bowel disease in the era of immunomodulators--a population-based study.

https://arctichealth.org/en/permalink/ahliterature133079
Source
Inflamm Bowel Dis. 2011 Aug;17(8):1731-40
Publication Type
Article
Date
Aug-2011
Author
Christian Jakobsen
Pia Munkholm
Anders Paerregaard
Vibeke Wewer
Author Affiliation
Department of Pediatrics, Hvidovre University Hospital, Copenhagen, Denmark. Christian.jakobsen@hvh.regionh.dk
Source
Inflamm Bowel Dis. 2011 Aug;17(8):1731-40
Date
Aug-2011
Language
English
Publication Type
Article
Keywords
6-Mercaptopurine - therapeutic use
Adolescent
Adrenal Cortex Hormones - therapeutic use
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Azathioprine - therapeutic use
Child
Child, Preschool
Colitis, Ulcerative - drug therapy - surgery
Crohn Disease - drug therapy - surgery
Denmark
Female
Follow-Up Studies
Humans
Immunosuppressive Agents - therapeutic use
Infant
Male
Mesalamine - therapeutic use
Remission Induction
Time Factors
Treatment Outcome
Abstract
The aim was to investigate the impact of systemic steroid treatment (SST) and immunomodulators (IM) on disease course in children with inflammatory bowel disease (IBD).
All IBD patients in eastern Denmark
PubMed ID
21744428 View in PubMed
Less detail

Steroid dependency and pediatric inflammatory bowel disease in the era of immunomodulators-A population-based study.

https://arctichealth.org/en/permalink/ahliterature99930
Source
Inflamm Bowel Dis. 2010 Dec 3;
Publication Type
Article
Date
Dec-3-2010
Author
Christian Jakobsen
Pia Munkholm
Anders Paerregaard
Vibeke Wewer
Author Affiliation
From the Department of Pediatrics, Hvidovre University Hospital, Copenhagen, Denmark.
Source
Inflamm Bowel Dis. 2010 Dec 3;
Date
Dec-3-2010
Language
English
Publication Type
Article
Abstract
BACKGROUND:: The aim was to investigate the impact of systemic steroid treatment (SST) and immunomodulators (IM) on disease course in children with inflammatory bowel disease (IBD). METHODS:: All IBD patients in eastern Denmark
PubMed ID
21132788 View in PubMed
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Surgery and postoperative recurrence in children with Crohn disease.

https://arctichealth.org/en/permalink/ahliterature273068
Source
J Pediatr Gastroenterol Nutr. 2015 Mar;60(3):347-51
Publication Type
Article
Date
Mar-2015
Author
Lars F Hansen
Christian Jakobsen
Anders Paerregaard
Niels Qvist
Vibeke Wewer
Source
J Pediatr Gastroenterol Nutr. 2015 Mar;60(3):347-51
Date
Mar-2015
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Cecum - surgery
Child
Cohort Studies
Colectomy - adverse effects
Combined Modality Therapy - adverse effects
Crohn Disease - physiopathology - prevention & control - surgery - therapy
Denmark
Female
Follow-Up Studies
Humans
Ileum - surgery
Male
Organ Sparing Treatments - adverse effects
Practice Patterns, Physicians'
Recurrence
Registries
Reoperation - adverse effects
Retrospective Studies
Severity of Illness Index
Survival Analysis
Young Adult
Abstract
The aim of this study was to describe surgery rates, complications, and risk of disease recurrence after surgery in paediatric Crohn disease (CD).
Children 10 years postoperatively, we found a high postoperative recurrence rate of disease and a frequent need for >1 intestinal resection.
PubMed ID
25373863 View in PubMed
Less detail

11 records – page 1 of 2.