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25 records – page 1 of 3.

Analysis of the macrophage scavenger receptor 1 gene in Swedish hereditary and sporadic prostate cancer.

https://arctichealth.org/en/permalink/ahliterature17838
Source
Prostate. 2004 May 1;59(2):132-40
Publication Type
Article
Date
May-1-2004
Author
Fredrik Lindmark
Björn-Anders Jonsson
Anders Bergh
Pär Stattin
S Lilly Zheng
Deborah A Meyers
Jianfeng Xu
Henrik Grönberg
Author Affiliation
Department of Radiation Sciences, Oncology, University of Umeå, Umeå, Sweden.
Source
Prostate. 2004 May 1;59(2):132-40
Date
May-1-2004
Language
English
Publication Type
Article
Keywords
Aged
Case-Control Studies
Cell Adhesion Molecules
Chromosomes, Human, Pair 8 - genetics
DNA - analysis
DNA Mutational Analysis
Genotype
Humans
Male
Middle Aged
Pedigree
Polymerase Chain Reaction
Polymorphism, Genetic
Prostatic Neoplasms - genetics
Receptors, Immunologic - genetics
Receptors, Scavenger
Research Support, Non-U.S. Gov't
Risk factors
Scavenger Receptors, Class A
Sweden
Abstract
BACKGROUND: The macrophage scavenger receptor 1 (MSR1) gene on chromosome 8p22 was recently reported as a candidate gene for hereditary prostate cancer (HPC). Here, we further elucidate the role of MSR1 in both Swedish families with HPC and in a cohort of unselected prostate cancer. METHODS: DNA samples from 83 Swedish HPC families and 215 unselected population based cases of prostate cancer as well as 425 age-matched controls were genotyped. RESULTS: A total of 18 variants were identified, including 2 exonic, 7 intronic changes, and 9 changes in the 5'- or 3'-uncoding region. Of the two exonic changes, one previously reported truncation mutation was identified, a R293X nonsense mutation. This mutation was found in 2 of the 83 (2.4%) HPC families. The R293X mutation was found more frequently in men with PC (4.9%) than in unaffected men (2.7%), consistent with previous published results, however our results were not significant (P = 0.16). To additionally test for potential association of common sequence variants and increased risk for the disease, five common polymorphisms (PRO3, INDEL1, IVS5-57, P275A, INDEL7) were genotyped in the group of 215 prostate cancer cases and 425 age-matched controls. No association between any of the five common sequence variants and prostate cancer were found. CONCLUSION: Our results suggest that mutations in MSR1 gene might play a role in prostate cancer susceptibility, particularly the R293X mutation. This study warrants further investigations of the role of MSR1 in prostate cancer etiology.
PubMed ID
15042613 View in PubMed
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Source
Emerg Nurse. 2009 Jul;17(4):16-9
Publication Type
Article
Date
Jul-2009
Author
Eric Fortes Lähdet
Bjorn-Ove Suserud
Anders Jonsson
Lars Lundberg
Author Affiliation
Sahlgrenska University Hospital, Gothenburg.
Source
Emerg Nurse. 2009 Jul;17(4):16-9
Date
Jul-2009
Language
English
Publication Type
Article
Keywords
Algorithms
Australasia
Canada
Europe
Humans
Military Nursing - methods
Severity of Illness Index
Triage - methods
Abstract
Several triage methods have been developed and adopted around the world but none has been devised for specific patient populations such as older people or those with special needs. This literature review outlines the development of triage since the 1950s, briefly discusses some of the models in use around the world, including one that is used in the care of older people, and outlines the issues that should be taken into account when deciding which method to adopt.
PubMed ID
19639800 View in PubMed
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Are suicides by jumping off bridges preventable? An analysis of 50 cases from Sweden.

https://arctichealth.org/en/permalink/ahliterature68280
Source
Accid Anal Prev. 2004 Jul;36(4):691-4
Publication Type
Article
Date
Jul-2004
Author
Per Lindqvist
Anders Jonsson
Anders Eriksson
Annika Hedelin
Ulf Björnstig
Author Affiliation
Department of Community Medicine and Rehabilitation, Umeå University, Umeå SE-907 12, Sweden. per.lindqvist@spo.sll.se
Source
Accid Anal Prev. 2004 Jul;36(4):691-4
Date
Jul-2004
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Environment Design
Female
Humans
Male
Middle Aged
Safety Management
Suicide - prevention & control - statistics & numerical data
Sweden
Abstract
This is a community-based sequential case series of 50 individuals who committed suicide by jumping from bridges in two regions of Sweden. Of the 50 subjects, 32 were men and 18 women, with a median age of 35 years. At least 40 had psychiatric problems. The frequency of suicide was highest during the summer months and during the weekends. A total of 27 bridges were used, with a total length of just under 9 km. Three bridges accounted for almost half of all suicides. Limiting the availability of one method of committing suicide is reported to reduce the overall suicide rate; why suicide and injury suicide preventive measures might be considered. Since this study demonstrates that few bridges attract suicide candidates, this injury mechanism needs to be acknowledged by the road system owners and included in the safety work.
PubMed ID
15094424 View in PubMed
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Assessing the number of fire fatalities in a defined population.

https://arctichealth.org/en/permalink/ahliterature274401
Source
J Safety Res. 2015 Dec;55:99-103
Publication Type
Article
Date
Dec-2015
Author
Anders Jonsson
Anders Bergqvist
Ragnar Andersson
Source
J Safety Res. 2015 Dec;55:99-103
Date
Dec-2015
Language
English
Publication Type
Article
Keywords
Adult
Burns - mortality
Databases, Factual
Female
Fires - statistics & numerical data
Humans
Public Health Surveillance
Sweden - epidemiology
Abstract
Fire-related fatalities and injuries have become a growing governmental concern in Sweden, and a national vision zero strategy has been adopted stating that nobody should get killed or seriously injured from fires. There is considerable uncertainty, however, regarding the numbers of both deaths and injuries due to fires. Different national sources present different numbers, even on deaths, which obstructs reliable surveillance of the problem over time. We assume the situation is similar in other countries. This study seeks to assess the true number of fire-related deaths in Sweden by combining sources, and to verify the coverage of each individual source. By doing so, we also wish to demonstrate the possibilities of improved surveillance practices.
Data from three national sources were collected and matched; a special database on fatal fires held by The Swedish Contingencies Agency (nationally responsible for fire prevention), a database on forensic medical examinations held by the National Board of Forensic Medicine, and the cause of death register held by the Swedish National Board of Health and Welfare.
The results disclose considerable underreporting in the single sources. The national database on fatal fires, serving as the principal source for policy making on fire prevention matters, underestimates the true situation by 20%. Its coverage of residential fires appears to be better than other fires.
Systematic safety work and informed policy-making presuppose access to correct and reliable numbers. By combining several different sources, as suggested in this study, the national database on fatal fires is now considerably improved and includes regular matching with complementary sources.
PubMed ID
26683552 View in PubMed
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Assessment of Use vs Discontinuation of Oral Anticoagulation After Pulmonary Vein Isolation in Patients With Atrial Fibrillation.

https://arctichealth.org/en/permalink/ahliterature300413
Source
JAMA Cardiol. 2017 02 01; 2(2):146-152
Publication Type
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Date
02-01-2017
Author
Sara Själander
Fredrik Holmqvist
J Gustav Smith
Pyotr G Platonov
Milos Kesek
Peter J Svensson
Carina Blomström-Lundqvist
Fariborz Tabrizi
Jari Tapanainen
Dritan Poci
Anders Jönsson
Anders Själander
Author Affiliation
Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Source
JAMA Cardiol. 2017 02 01; 2(2):146-152
Date
02-01-2017
Language
English
Publication Type
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Keywords
Administration, Oral
Age Factors
Anticoagulants - administration & dosage
Atrial Fibrillation - complications - drug therapy - surgery
Brain Ischemia - epidemiology - etiology - prevention & control
Catheter Ablation - methods
Cause of Death - trends
Female
Follow-Up Studies
Humans
Incidence
Male
Middle Aged
Prognosis
Pulmonary Veins - surgery
Retrospective Studies
Risk Assessment - methods
Risk factors
Survival Rate - trends
Sweden - epidemiology
Time Factors
Warfarin - administration & dosage
Withholding Treatment
Abstract
Pulmonary vein isolation (PVI) is a recommended treatment for patients with atrial fibrillation, but it is unclear whether it results in a lower risk of stroke.
To investigate the proportion of patients discontinuing anticoagulation treatment after PVI in association with the CHA2DS2-VASc (congestive heart failure, hypertension, age =75 years [doubled], diabetes, stroke [doubled], vascular disease, age 65-74 years, sex category [female]) score, identify factors predicting stroke after PVI, and explore the risk of cardiovascular events after PVI in patients with and without guideline-recommended anticoagulation treatment.
A retrospective cohort study was conducted using Swedish national health registries from January 1, 2006, to December 31, 2012, with a mean-follow up of 2.6 years. A total of 1585 patients with atrial fibrillation undergoing PVI from the Swedish Catheter Ablation Register were included, with information about exposure to warfarin in the national quality register Auricula. Data analysis was performed from January 1, 2015, to April 30, 2016.
Warfarin treatment.
Ischemic stroke, intracranial hemorrhage, and death.
In this cohort of 1585 patients, 73.0% were male, the mean (SD) age was 59.0 (9.4) years, and the mean (SD) CHA2DS2-VASc score was 1.5 (1.4). Of the 1585 patients, 1175 were followed up for more than 1 year after PVI. Of these, 360 (30.6%) discontinued warfarin treatment during the first year. In patients with a CHA2DS2-VASc score of 2 or more, patients discontinuing warfarin treatment had a higher rate of ischemic stroke (5 events in 312 years at risk [1.6% per year]) compared with those continuing warfarin treatment (4 events in 1192 years at risk [0.3% per year]) (P?=?.046). Patients with a CHA2DS2-VASc score of 2 or more or those who had previously experienced an ischemic stroke displayed a higher risk of stroke if warfarin treatment was discontinued (hazard ratio, 4.6; 95% CI, 1.2-17.2; P?=?.02 and hazard ratio, 13.7; 95% CI, 2.0-91.9; P?=?.007, respectively).
These findings indicate that discontinuation of warfarin treatment after PVI is not safe in high-risk patients, especially those who have previously experienced an ischemic stroke.
Notes
CommentIn: JAMA Cardiol. 2017 Feb 1;2(2):152-154 PMID 27893050
PubMed ID
27893055 View in PubMed
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Baby boomers as future care users--An analysis of expectations in print media.

https://arctichealth.org/en/permalink/ahliterature272016
Source
J Aging Stud. 2015 Aug;34:82-91
Publication Type
Article
Date
Aug-2015
Author
Håkan Jönson
Anders Jönsson
Source
J Aging Stud. 2015 Aug;34:82-91
Date
Aug-2015
Language
English
Publication Type
Article
Keywords
Aged
Forecasting
Health services needs and demand
Health Services for the Aged - trends - utilization
Humans
Negotiating - psychology
Newspapers as Topic
Patient Acceptance of Health Care
Patient Participation - psychology
Population Growth
Self Concept
Social Identification
Sweden
Abstract
The aim of the study was to investigate media presentations of baby boomers as future care users. The Swedish baby boomer generation, born in the 1940s, and known as the '40s generation, has been characterized as youthful and powerful, and a question investigated in the study was whether boomers are supposed to display these characteristics as care users. We analyzed 481 articles in Swedish newspapers, published between 1995 and 2012, with a qualitative content analysis. The results showed that the '40s generation was predicted to become a new breed of demanding, self-aware care users. These claims were supported by descriptions of the formative events and typical characteristics of these individuals, which were then projected onto their future behavior as care users. Such projections tended to portray contemporary care users as passive, submissive, and partly responsible for problems associated with elder care. Consequently, approaches that focus on differences between cohorts need to incorporate a constructionist dimension to highlight the problem of generationism.
PubMed ID
26162728 View in PubMed
Less detail
Source
Emerg Nurse. 2013 Nov;21(7):14-8
Publication Type
Article
Date
Nov-2013
Author
Björn-Ove Suserud
Anders Jonsson
Anders Johansson
Kerstin Petzäll
Source
Emerg Nurse. 2013 Nov;21(7):14-8
Date
Nov-2013
Language
English
Publication Type
Article
Keywords
Ambulances
Automobile Driving
Humans
Nurses
Safety
Sweden
Abstract
The aim of this article is to explore whether ambulance clinicians in Sweden perceive their working environment to be safe.
Twenty four ambulance nurses and nine paramedics at five ambulance stations in urban and rural areas of Sweden were interviewed.
After transcripts of the interviews had been analysed, nine issues that affect how participants perceive the safety of patient care in ambulances emerged: planning before departure; use of safety belts; driving at high speeds; patient first, safety second; equipment design and placement; noise; driving styles; presence of relatives; documentation.
Ambulance personnel should have greater involvement in the design of ambulance care spaces and drivers should be given more regular training.
PubMed ID
24219684 View in PubMed
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Change in mitral regurgitation severity impacts survival after transcatheter aortic valve replacement.

https://arctichealth.org/en/permalink/ahliterature310133
Source
Int J Cardiol. 2019 11 01; 294:32-36
Publication Type
Journal Article
Date
11-01-2019
Author
Kari Feldt
Rodney De Palma
Henrik Bjursten
Petur Petursson
Niels Erik Nielsen
Thomas Kellerth
Anders Jönsson
Johan Nilsson
Andreas Rück
Magnus Settergren
Author Affiliation
Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden; Heart and Vascular Theme, Department of Cardiology, Karolinska University Hospital, 171 76 Stockholm, Sweden. Electronic address: kari.feldt@ki.se.
Source
Int J Cardiol. 2019 11 01; 294:32-36
Date
11-01-2019
Language
English
Publication Type
Journal Article
Keywords
Aged, 80 and over
Aortic Valve Stenosis - surgery
Comorbidity
Echocardiography
Female
Heart Valve Prosthesis
Humans
Male
Mitral Valve Insufficiency - mortality - physiopathology
Prognosis
Registries
Severity of Illness Index
Survival Rate
Sweden
Transcatheter Aortic Valve Replacement - adverse effects - mortality
Abstract
The impact of a change in mitral regurgitation (MR) following TAVR is unknown. We studied the impact of baseline MR and early post-procedural change in MR on survival following TAVR.
The SWEDEHEART registry included all TAVRs performed in Sweden. Patients were dichotomized into no/mild and moderate/severe MR groups. Vital status, echocardiographic data at baseline and within 7?days after TAVR were analyzed.
1712 patients were included. 1404 (82%) had no/mild MR and 308 (18%) had moderate/severe MR. Baseline moderate/severe MR conferred a higher mortality rate at 5-year follow-up (adjusted HR 1.29, CI 1.01-1.65, p?=?0.04). Using persistent =mild MR as the reference, when moderate/severe MR persisted or if MR worsened from =mild at baseline to moderate/severe after TAVR, higher 5-year mortality rates were seen (adjusted HR 1.66, CI 1.17-2.34, p?=?0.04; adjusted HR 1.97, CI 1.29-3.00, p?=?0.002, respectively). If baseline moderate/severe MR improved to =mild after TAVR no excess mortality was seen (HR 1.09, CI 0.75-1.58, p?=?0.67). Paravalvular aortic regurgitation (PVL) was inversely associated with MR improvement after TAVR (OR 0.4, 95%: CI 0.17-0.94; p?=?0.034). Atrial fibrillation (OR 2.1, 95% CI: 1.27-3.39, p?=?0.004), self-expanding valve (OR 3.8, 95% CI: 2.08-7.14, p?
PubMed ID
31399298 View in PubMed
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Daily stress and concept of self in Swedish ambulance personnel.

https://arctichealth.org/en/permalink/ahliterature70839
Source
Prehospital Disaster Med. 2004 Jul-Sep;19(3):226-34
Publication Type
Article
Author
Anders Jonsson
Kerstin Segesten
Author Affiliation
Hogskolan I Boras School of Health Sciences, Goteborg University Faculty of Medicine, Department of Primary Health Care, Boras, Sweden. Anders.Jonsson@hb.se
Source
Prehospital Disaster Med. 2004 Jul-Sep;19(3):226-34
Language
English
Publication Type
Article
Keywords
Adult
Ambulances
Burnout, Professional - epidemiology - prevention & control - psychology
Emergency Medical Technicians - psychology
Emergency Nursing
Factor Analysis, Statistical
Female
Humans
Male
Middle Aged
Self Concept
Statistics, nonparametric
Stress Disorders, Post-Traumatic - epidemiology - prevention & control - psychology
Sweden - epidemiology
Abstract
INTRODUCTION: This study investigated the prevalence of post-traumatic stress symptoms among professional ambulance personnel in Sweden and investigated the question: "Does self-knowledge have influence on how well one copes with the effects of daily work exposure from such events?" Little is known about the variables that might be associated with post-traumatic stress symptoms in high-risk occupational groups such as ambulance service groups. METHODS: Data were gathered from ambulance personnel by means of an anonymous questionnaire. Survey responses of 362 ambulance personnel from the county of Västra Götaland were analyzed. A correlation was established between post-traumatic symptoms using the impact of event scale (IES-15) and the Professional Self-Description Form (PSDF). RESULTS: Of those who reported a traumatic situation, 21.5% scored > or =26 on the IES-15 subscale. Scores >26 indicate "PTSD caseness". There were significant differences on PSDF subscales between those presenting with or without post-traumatic symptoms. CONCLUSIONS: The mental health and emotional well-being of ambulance personnel appear to be compromised by accident and emergency work. The high prevalence of PTSD symptoms in ambulance personnel indicates an inability to cope with post-traumatic stress caused by daily work experiences.
PubMed ID
15571199 View in PubMed
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25 records – page 1 of 3.