Skip header and navigation

Refine By

5 records – page 1 of 1.

Development of hypertensive status in NISAG rats reared by normotensive Wistar rats.

https://arctichealth.org/en/permalink/ahliterature10095
Source
Bull Exp Biol Med. 2001 Aug;132(2):734-6
Publication Type
Article
Date
Aug-2001
Author
G S Yakobson
A R Antonov
A L Markel'
S Y Amstislavskii
A G Taranov
M G Yakobson
Author Affiliation
Institute of Physiology, Siberian Division of the Russian Academy of Medical Science.
Source
Bull Exp Biol Med. 2001 Aug;132(2):734-6
Date
Aug-2001
Language
English
Publication Type
Article
Keywords
Animals
Animals, Newborn
Blood pressure
Comparative Study
Corticosterone - blood
Electrocardiography
Female
Hypertension - blood - etiology - physiopathology
In Vitro
Male
Norepinephrine - analysis
Perfusion
Rats
Rats, Inbred Strains
Rats, Wistar
Research Support, Non-U.S. Gov't
Thyrotropin - blood
Thyroxine - blood
Triiodothyronine - blood
Abstract
Parameters of the cardiovascular system and the content of corticosterone, thyrotrophin, thyroxin, and triiodothyronine in the plasma, and norepinephrine in the myocardium were determined in male NISAG rats (hereditary stress-induced arterial hypertension) reared by normotensive Wistar rats. Cross-rearing of hypertensive rat pups by normotensive females attenuated arterial hypertension with a tendency to normalization of the examined parameters. This confirms the possibility of modifying hypertensive phenotype by changing the conditions of the early postnatal development.
PubMed ID
11713551 View in PubMed
Less detail

Iron content and parameters of blood antioxidant activity in rats with hereditary arterial hypertension during experimental myocardial infarction.

https://arctichealth.org/en/permalink/ahliterature53787
Source
Bull Exp Biol Med. 2001 Nov;132(5):1041-4
Publication Type
Article
Date
Nov-2001
Author
M G Yakobson
A R Antonov
A V Golovatyuk
A V Efremov
A L Markel'
G S Yakobson
Author Affiliation
Institute of Physiology, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
Source
Bull Exp Biol Med. 2001 Nov;132(5):1041-4
Date
Nov-2001
Language
English
Publication Type
Article
Keywords
Animals
Antioxidants - metabolism - pharmacology
Hypertension - metabolism
Iron - metabolism
Lymph Nodes - metabolism
Male
Myocardial Infarction - metabolism
Myocardium - metabolism
Rats
Rats, Wistar
Time Factors
Abstract
Plasma, lymph and myocardial Fe(2+) contents and blood antioxidant activity were studied in hypertensive NISAG and normotensive Wistar rats with experimental myocardial infarction. In hypertensive rats, iron levels in plasma, lymph and myocardial tissue were increased throughout the experiment. In both strains iron content in the plasma during experimental myocardial infarction negatively correlated with blood antioxidant activity. In hypertensive NISAG rats this correlation persisted also during recovery. This attests to prooxidant effect of Fe(2+) aggravating the course of myocardial infarction in NISAG rats.
PubMed ID
11865316 View in PubMed
Less detail

[Ontogenetic dynamics of blood pressure and characteristics of EKG in rats of NISAG line with congenital arterial hypertension]

https://arctichealth.org/en/permalink/ahliterature54504
Source
Biull Eksp Biol Med. 1997 Jun;123(6):709-13
Publication Type
Article
Date
Jun-1997

Pathophysiological aspects of experimental myocardial infarction during arterial hypertension.

https://arctichealth.org/en/permalink/ahliterature53400
Source
Bull Exp Biol Med. 2003 Nov;136(5):444-7
Publication Type
Article
Date
Nov-2003
Author
G S Yakobson
A R Antonov
A V Efremov
N A Makhanova
M D Shmerling
V F Maksimov
I M Korostyshevskaya
M G Yakobson
Author Affiliation
Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia.
Source
Bull Exp Biol Med. 2003 Nov;136(5):444-7
Date
Nov-2003
Language
English
Publication Type
Article
Keywords
Adult
Aldosterone - blood
Animals
Blood pressure
Case-Control Studies
Comparative Study
Disease Models, Animal
Humans
Hypertension - genetics - metabolism - physiopathology
Male
Middle Aged
Myocardial Infarction - blood - physiopathology
Rats
Rats, Inbred SHR
Rats, Wistar
Abstract
We compared the results of clinical and experimental studies of endocrine parameters in patients with myocardial infarction and arterial hypertension and NISAG rats with hereditary stress-induced arterial hypertension during experimental myocardial infarction. Changes in the content of corticosterone, aldosterone, insulin, triiodothyronine, and thyroxin were similar in animals and patients with myocardial infarction and arterial hypertension. The disadaptive course of myocardial infarction against the background of arterial hypertension can be explained by reduced compensatory capacity of the myocardium.
PubMed ID
14968155 View in PubMed
Less detail

Selenium content and blood antioxidant activity in rats with hereditary arterial hypertension during experimental myocardial infarction.

https://arctichealth.org/en/permalink/ahliterature53842
Source
Bull Exp Biol Med. 2001 Jul;132(1):641-3
Publication Type
Article
Date
Jul-2001
Author
G S Yakobson
A R Antonov
A V Golovatyuk
A L Markel'
M G Yakobson
Author Affiliation
Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
Source
Bull Exp Biol Med. 2001 Jul;132(1):641-3
Date
Jul-2001
Language
English
Publication Type
Article
Keywords
Animals
Antioxidants - metabolism
Hypertension - blood - complications - genetics - metabolism
Lymph - metabolism
Male
Myocardial Infarction - blood - complications - metabolism
Myocardium - metabolism
Rats
Rats, Inbred Strains
Rats, Wistar
Selenium - blood - metabolism
Abstract
The dynamics of selenium content in the plasma, lymph, and myocardium and plasma antioxidant activity were studied in male NISAG (hereditary stress-induced arterial hypertension) and Wistar rats with acute myocardial infarction and during recovery.In NISAG rats the decrease in selenium content correlated with the decrease in antioxidant activity. This probably aggravates the symptoms of experimental myocardial infarction in animals with hereditary arterial hypertension.
PubMed ID
11687841 View in PubMed
Less detail