Unfavourable sanitary and hygienic conditions in 2 settlements have been established; the authors revealed specific features of the invasion spreading in this focus where high invasion rates of intermediate and final hosts were associated with low invasion rates. Different factors have been established, which contribute to the invasion spreading among the population. A three-score assessment has been proposed of the manifestations of the clinical symptomatology in digestive disease in opisthorchiasis which is suitable for in the field. A retrospective analysis has been made of the reasons for ineffective chemotherapy with chloxyl in this focus. The age-related affliction with opisthorchiasis in the focus is the most adequately described by a "reversible catalytic" model with a force of infection of 0.055.
Dirofilaria repens Railliet et Henry, 1911 was for the first time studied in the Moscow Region where 11 patients (6 males and 5 females) aged 4-72 years were recorded in 2000-2002. The geographical distribution (the southern and south-eastern parts of the region) of local cases of dirofiliriasis, was observed. There was a relatively high rate of D. repens in the male genitalia of the infected patients as compared with that reported by other authors. In accordance with the current terminology, D. repens in the Moscow Region is proposed to be regarded as emerging infection. The authors show it necessary to obligatorily record all autochtonous cases of D. repens infection, to make epidemiological surveillance and analysis in order to early detect and prevent dirofilariasis-associated complications.
A focus of metagonimiasis and nanophyetiasis is described with the average human prevalence of 66.7 and 4.2%, respectively and low intensity of invasions (less than 100 eggs per 1 g). Metagonimiasis and nanophyetiasis are clinically expressed as chronic enterocolitis. A high effect of a single dose 10 mg/kg of azinox against metagonimiasis (98%) and nanophyetiasis (100%) was shown. The treatment course was proved to be useful in the foci of the Amur basin.
49% of patients who abused alcohol were detected among 119 persons with O. felineus infection in the focus of the infection in the Komi-Permiak Autonomous Okrug by screening questionnaire test. The abuse of alcohol in the given focus was shown to be associated with consumption of low-salt fish mostly by men. Alcoholism promotes failure to keep medical recommendations on the prevention of Opisthorchis infection and reduced motivation of opisthorchiasis treatment, and due to re- and superinvasion it decreases the efficiency of chemotherapy. Comparing the results of praziquantel treatment a month or a year after, treatment efficiency among those abusing alcohol was shown to decrease from 88% to 68%.