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Efficacy and tolerability of a fixed-dose combination of telmisartan plus hydrochlorothiazide in patients uncontrolled with telmisartan monotherapy.

https://arctichealth.org/en/permalink/ahliterature192670
Source
J Hum Hypertens. 2001 Nov;15(11):763-70
Publication Type
Article
Date
Nov-2001
Author
Y. Lacourcière
R. Tytus
D. O'Keefe
J. Lenis
R. Orchard
K. Martin
Author Affiliation
Hypertension Research Unit, Centre Hospitalier Universitaire de Québec, Québec, Canada. luc.poirier@crchul.ulaval.ca
Source
J Hum Hypertens. 2001 Nov;15(11):763-70
Date
Nov-2001
Language
English
Publication Type
Article
Keywords
Adult
Aged
Antihypertensive Agents - administration & dosage - adverse effects
Benzimidazoles - administration & dosage - adverse effects
Benzoates - administration & dosage - adverse effects
Blood Pressure - drug effects
Canada - epidemiology
Dose-Response Relationship, Drug
Double-Blind Method
Drug Therapy, Combination
Female
Follow-Up Studies
Humans
Hydrochlorothiazide - administration & dosage - adverse effects
Hypertension - drug therapy - prevention & control
Male
Middle Aged
Patient compliance
Prospective Studies
Treatment Outcome
Abstract
The antihypertensive effects of a telmisartan 80 mg/hydrochlorothiazide (HCTZ) 12.5 mg fixed-dose combination and telmisartan 80 mg monotherapy were compared in patients with a history of mild-to-moderate essential hypertension and inadequate BP control (DBP > or = 90 mm Hg) following 8 weeks of telmisartan monotherapy. At the end of this period, 491 patients (62.9% men; mean age 55.3 years) whose DBP was > or = 90 mm Hg were double-blind randomised to once-daily telmisartan 80 mg/HCTZ 12.5 mg (n = 246) or telmisartan 80 mg (n = 245). Trough (24 h post-dose) clinic BP was measured after 4 and 8 weeks of double-blind therapy. At the end of double-blind treatment, patients receiving telmisartan 80 mg/HCTZ 12.5 mg had significant additional decrements in clinic SBP/DBP over telmisartan 80 mg of -5.7/-3.1 mm Hg (P
PubMed ID
11687919 View in PubMed
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Report of the Canadian Hypertension Society Consensus Conference: 2. Diagnosis of hypertension in adults.

https://arctichealth.org/en/permalink/ahliterature220515
Source
CMAJ. 1993 Aug 15;149(4):409-18
Publication Type
Conference/Meeting Material
Article
Date
Aug-15-1993
Author
R B Haynes
Y. Lacourcière
S W Rabkin
F H Leenen
A G Logan
N. Wright
C E Evans
Author Affiliation
Health Information Research Unit, McMaster University, Hamilton, Ont.
Source
CMAJ. 1993 Aug 15;149(4):409-18
Date
Aug-15-1993
Language
English
Publication Type
Conference/Meeting Material
Article
Keywords
Adult
Aged
Ambulatory Care
Blood Pressure Determination - methods
Canada
Echocardiography
Female
Humans
Hypertension - diagnosis - therapy
Hypertrophy, Left Ventricular - ultrasonography
Male
Middle Aged
Office Visits
Self Care
Abstract
To update recommendations for the diagnosis of mild hypertension in adults and to assess the role of echocardiography, self-measurement of blood pressure and ambulatory blood pressure monitoring.
Literature reviews of previous consensus conferences were updated with searches of MEDLINE for the period Jan. 1, 1988, to Nov. 15, 1991, and supplemented by reference lists and personal files.
Panel members selected relevant articles and rated them according to methodologic criteria.
The data extracted concerned the measurement of blood pressure, the diagnosis of hypertension, the treatment of mild hypertension, and the reliability and validity of echocardiography, self-measurement of blood pressure and ambulatory blood pressure monitoring in the diagnosis of mild hypertension. The recommendations made were graded according to the level of evidence available, circulated to many experts and approved at a consensus conference.
Previous recommendations for the accurate measurement of blood pressure remain mostly unchanged. Antihypertensive treatment should be prescribed for patients (including the elderly) with an average diastolic blood pressure of at least 100 mm Hg, for those with isolated systolic hypertension (systolic blood pressure of at least 160 mm Hg and diastolic blood pressure of less than 90 mm Hg) and for patients with a diastolic blood pressure of 90 to 99 mm Hg and target-organ damage. Clinical judgement is required in treating patients with a diastolic blood pressure of 90 to 99 mm Hg without target-organ damage, and individual risk for cardiovascular disease must be taken into account. There is insufficient evidence to warrant the routine use of echocardiography, self-measurement of blood pressure or ambulatory blood pressure monitoring in diagnosis.
Recent high-quality evidence supports several new recommendations for the diagnosis of mild hypertension in adults. Additional research is needed to determine the role of echocardiography, self-measurement of blood pressure and ambulatory blood pressure monitoring.
Notes
Cites: Can Med Assoc J. 1984 Nov 1;131(9):1053-76149806
Cites: J Am Coll Cardiol. 1984 Dec;4(6):1222-306238987
Cites: Clin Exp Hypertens A. 1985;7(2-3):267-783159516
Cites: Lancet. 1985 Jun 15;1(8442):1349-542861311
Cites: Ann Intern Med. 1986 Aug;105(2):173-82942070
Cites: J Hypertens. 1986 Jun;4(3):369-743734455
Cites: J Hypertens. 1987 Feb;5(1):93-83584967
Cites: Lancet. 1987 Aug 8;2(8554):322-42886776
Cites: JAMA. 1988 Jan 8;259(2):225-83336140
Cites: J Hypertens. 1988 Jan;6(1):9-153351298
Cites: Hypertension. 1988 Jun;11(6 Pt 1):545-93384470
Cites: Angiology. 1988 Aug;39(8):752-603421509
Cites: Am Heart J. 1988 Oct;116(4):1152-43177190
Cites: Am Heart J. 1988 Oct;116(4):1155-603177191
Cites: JAMA. 1989 Feb 10;261(6):873-72521522
Cites: J Hypertens. 1989 Feb;7(2):133-422926132
Cites: Circulation. 1966 Aug;34(2):279-985969359
Cites: Circulation. 1967 Dec;36(6):980-86061343
Cites: Circulation. 1969 Aug;40(2):185-954240354
Cites: J Chronic Dis. 1971 Mar;23(10):723-544933751
Cites: Am J Cardiol. 1974 Jan;33(1):107-104808549
Cites: JAMA. 1982 Aug 6;248(5):555-87047770
Cites: Br Med J (Clin Res Ed). 1982 Aug 14;285(6340):469-716809128
Cites: Med Care. 1982 Jul;20(7):727-387121092
Cites: Br Med J (Clin Res Ed). 1982 Dec 11;285(6356):1691-46816333
Cites: JAMA. 1983 May 27;249(20):2792-86842787
Cites: J Am Coll Cardiol. 1983 Aug;2(2):305-116223063
Cites: Circulation. 1983 Sep;68(3):470-66223721
Cites: Hypertension. 1984 Jul-Aug;6(4):574-86235190
Cites: CMAJ. 1989 May 15;140(10):1141-62565758
Cites: J Gen Intern Med. 1989 May-Jun;4(3):226-312786060
Cites: BMJ. 1989 Jun 10;298(6687):1552-62503114
Cites: J Hypertens Suppl. 1989 May;7(3):S59-632760717
Cites: Ann Intern Med. 1990 Feb 15;112(4):270-72297205
Cites: Arch Intern Med. 1970 Jun;125(6):1000-34951927
Cites: Am J Hypertens. 1990 Feb;3(2):81-92137704
Cites: Lancet. 1990 Apr 7;335(8693):827-381969567
Cites: J Hum Hypertens. 1990 Feb;4 Suppl 1:47-502182869
Cites: N Engl J Med. 1990 May 31;322(22):1561-62139921
Cites: JAMA. 1990 Jul 18;264(3):354-82362331
Cites: Klin Wochenschr. 1990 Jul 17;68(14):723-72391953
Cites: Am J Cardiol. 1990 Sep 1;66(5):583-902144095
Cites: Hypertension. 1990 Dec;16(6):617-232246029
Cites: N Engl J Med. 1991 Mar 21;324(12):781-81900101
Cites: J Hypertens Suppl. 1990 Dec;8(6):S57-642150534
Cites: J Hypertens Suppl. 1991 Jan;9(1):S33-9; discussion S39-402040905
Cites: J Hypertens Suppl. 1991 Jan;9(1):S7-11; discussion S11-22040906
Cites: J Hum Hypertens. 1990 Dec;4(6):639-452096205
Cites: Ann Intern Med. 1991 Aug 15;115(4):287-931854113
Cites: Clin Invest Med. 1991 Jun;14(3):231-401893656
Cites: Lancet. 1991 Nov 23;338(8778):1281-51682683
Cites: CMAJ. 1993 Aug 1;149(3):289-938339174
Cites: J Chronic Dis. 1964 May;17:391-614143897
Cites: JAMA. 1974 Aug 5;229(6):663-64408228
Cites: Can J Public Health. 1974 Nov-Dec;65(6):447-504434304
Cites: Br Med J. 1976 Apr 10;1(6014):886-81260385
Cites: J Chronic Dis. 1977 Jan;30(1):7-18833249
Cites: J Am Dent Assoc. 1977 Jul;95(1):98-102267661
Cites: Arch Intern Med. 1977 Sep;137(9):1125-9901081
Cites: N Engl J Med. 1978 Oct 5;299(14):741-4692548
Cites: Br Med J. 1979 Mar 24;1(6166):789-90435796
Cites: J Chronic Dis. 1979;32(6):451-61457829
Cites: J Chronic Dis. 1979;32(8):577-81468959
Cites: Br Med J. 1979 Sep 29;2(6193):775-6519193
Cites: J Chronic Dis. 1980;33(4):197-2067358822
Cites: Am J Nurs. 1980 May;80(5):942-66901466
Cites: Prim Care. 1980 Dec;7(4):637-517010403
Cites: J Chronic Dis. 1981;34(5):191-2097240360
Cites: J Chronic Dis. 1981;34(11):527-317287857
Cites: N Engl J Med. 1982 Jan 14;306(2):108-97053478
Cites: Dan Med Bull. 1981 Oct;28(5):197-2007327004
Cites: Clin Invest Med. 1981;4(3-4):201-77337992
Cites: Lancet. 1982 Jul 3;2(8288):33-66123760
PubMed ID
8348423 View in PubMed
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