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The 6-Minute Walk Test as a Predictor of Summit Success on Denali.

https://arctichealth.org/en/permalink/ahliterature279175
Source
Wilderness Environ Med. 2016 Mar;27(1):19-24
Publication Type
Article
Date
Mar-2016
Author
Katherine M Shea
Eric R Ladd
Grant S Lipman
Patrick Bagley
Elizabeth A Pirrotta
Hurnan Vongsachang
N Ewen Wang
Paul S Auerbach
Source
Wilderness Environ Med. 2016 Mar;27(1):19-24
Date
Mar-2016
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Alaska
Female
Humans
Male
Middle Aged
Mountaineering - statistics & numerical data
Prospective Studies
Walk Test - methods
Young Adult
Abstract
To test whether the 6-minute walk test (6MWT), including postexercise vital sign measurements and distance walked, predicts summit success on Denali, AK.
This was a prospective observational study of healthy volunteers between the ages of 18 and 65 years who had been at 4267 m for less than 24 hours on Denali. Physiologic measurements were made after the 6MWT. Subjects then attempted to summit at their own pace and, at the time of descent, completed a Lake Louise Acute Mountain Sickness Questionnaire and reported maximum elevation reached.
One hundred twenty-one participants enrolled in the study. Data were collected on 111 subjects (92% response rate), of whom 60% summited. On univariate analysis, there was no association between any postexercise vital sign and summit success. Specifically, there was no significant difference in the mean postexercise peripheral oxygen saturation (Spo2) between summiters (75%) and nonsummiters (74%; 95% CI, -3 to 1; P = .37). The distance a subject walked in 6 minutes (6MWTD) was longer in summiters (617 m) compared with nonsummiters (560 m; 95% CI, 7.6 to 106; P = .02). However, this significance was not maintained on a multivariate analysis performed to control for age, sex, and guide status (P = .08), leading to the conclusion that 6MWTD was not a robust predictor of summit success.
This study did not show a correlation between postexercise oxygen saturation or 6MWTD and summit success on Denali.
PubMed ID
26712335 View in PubMed
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A 7-year retrospective review from 2005 to 2011 of Propionibacterium acnes shoulder infections in Ottawa, Ontario, Canada.

https://arctichealth.org/en/permalink/ahliterature117999
Source
Diagn Microbiol Infect Dis. 2013 Feb;75(2):195-9
Publication Type
Article
Date
Feb-2013
Author
Bing Wang
Baldwin Toye
Marc Desjardins
Peter Lapner
Craig Lee
Author Affiliation
Division of Microbiology, Department of Pathology and Laboratory Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada.
Source
Diagn Microbiol Infect Dis. 2013 Feb;75(2):195-9
Date
Feb-2013
Language
English
Publication Type
Article
Keywords
Adult
Aged
Arthroplasty
Chi-Square Distribution
Female
Gram-Positive Bacterial Infections - epidemiology - microbiology
Humans
Joint Diseases - epidemiology - microbiology
Male
Middle Aged
Ontario - epidemiology
Propionibacterium acnes - isolation & purification
Prosthesis-Related Infections - epidemiology - microbiology
Retrospective Studies
Shoulder Joint - microbiology
Abstract
This study evaluated the clinical factors associated with Propionibacterium acnes shoulder infection and the standard culture procedures for isolating P. acnes from shoulder specimens by a 7-year retrospective analysis. P. acnes was incriminated as the second most common pathogen in 17 of 80 patients with positive shoulder cultures. All of the 17 patients had prior shoulder implant. The cumulative rates for isolating P. acnes were 1.9%, 1.9%, 41.9%, 96.4%, and 100% at day 1 to day 5 of incubation, respectively. The standard practice of anaerobic culture was able to detect P. acnes from shoulder specimens in patients with a clinical suspicion of infection. The sensitivity and specificity of prolonged incubation remain to be determined.
PubMed ID
23246074 View in PubMed
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(90)Sr in King Bolete Boletus edulis and certain other mushrooms consumed in Europe and China.

https://arctichealth.org/en/permalink/ahliterature275929
Source
Sci Total Environ. 2016 Feb 1;543(Pt A):287-94
Publication Type
Article
Date
Feb-1-2016
Author
Michal Saniewski
Tamara Zalewska
Grazyna Krasinska
Natalia Szylke
Yuanzhong Wang
Jerzy Falandysz
Source
Sci Total Environ. 2016 Feb 1;543(Pt A):287-94
Date
Feb-1-2016
Language
English
Publication Type
Article
Keywords
Agaricales - chemistry
Basidiomycota - chemistry
China
Food Contamination - analysis - statistics & numerical data
Radiation monitoring
Soil Pollutants, Radioactive - analysis
Strontium Radioisotopes - analysis
Sweden
Abstract
The (90)Sr activity concentrations released from a radioactive fallout have been determined in a range of samples of mushrooms collected in Poland, Belarus, China, and Sweden in 1996-2013. Measurement of (90)Sr in pooled samples of mushrooms was carried out with radiochemical procedure aimed to pre-isolate the analyte from the fungal materials before it was determined using the Low-Level Beta Counter. Interestingly, the Purple Bolete Imperator rhodopurpureus collected from Yunnan in south-western China in 2012 showed (90)Sr activity concentration at around 10 Bq kg(-1) dry biomass, which was greater when compared to other mushrooms in this study. The King Bolete Boletus edulis from China showed the (90)Sr activity in caps at around 1.5 Bq kg(-1) dry biomass (whole fruiting bodies) in 2012 and for specimens from Poland activity was well lower than 1.0 Bq kg(-1) dry biomass in 1998-2010. A sample of Sarcodonimbricatus collected in 1998 from the north-eastern region of Poland impacted by Chernobyl fallout showed (90)Sr in caps at around 5 Bq kg(-1) dry biomass. Concentration of (90)Sr in Bay Bolete Royoporus (Xerocomus or Boletus) badius from affected region of Gomel in Belarus was in 2010 at 2.1 Bq kg(-1) dry biomass. In several other species from Poland (90)Sr was at
PubMed ID
26590866 View in PubMed
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[100,000 more adults visit the dentist: a few results of November 1989]

https://arctichealth.org/en/permalink/ahliterature73759
Source
Nor Tannlaegeforen Tid. 1990 Jun;100(10):414-22
Publication Type
Article
Date
Jun-1990
Author
J. Grytten
D. Holst
I. Rossow
O. Vasend
N. Wang
Author Affiliation
Odontologiske Fakultet, Universitetet i Oslo.
Source
Nor Tannlaegeforen Tid. 1990 Jun;100(10):414-22
Date
Jun-1990
Language
Norwegian
Publication Type
Article
Keywords
Adult
Aged
Anxiety - epidemiology
Attitude to Health
DMF Index
Dental Care - economics - psychology
Dental Health Services - utilization
English Abstract
Female
Humans
Male
Middle Aged
Norway - epidemiology
Oral Hygiene
Abstract
The aim of the present study was to describe the Norwegian adult population according to: 1. number of teeth present, 2. demand and utilization of dental services, 3. travel time from home to the dentist, 4. dental health behaviour, 5. fear for dental treatment. The analyses were performed on a set of national data collected in 1989, which was representative of the non-institutionalized Norwegian population 20 years and above. The sample size was 1260 individuals. About 75% of the people had 20 teeth or more present. Nine percent were edentulous. Seventy-seven percent who had demanded dental services during the last year. The average expenditure for dental treatment for those who had demanded the services during the last year was NOK 826. Fifty-three percent travelled 15 minutes or less from home to the dentist. Eighteen percent travelled 30 minutes or more. Almost everybody with their own teeth present brushed their teeth regularly once a day. Thirty-three percent of all dentate people used woodsticks regularly once a day, while 20% used toothfloss regularly. Seventy-five percent had no to mild fear of the dentist, while 7% had a strong fear. Fear of the dentist was higher among women than among men. Fear of the dentist decreased by increasing age. Few people, less than 4%, had cancelled a dental appointment because of dental anxiety. There has been an improvement in dental health and dental health behaviour in Norway during the 1970's and 1980's. These improvements are discussed with special attention paid to the findings from the present study.
PubMed ID
2247358 View in PubMed
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450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy.

https://arctichealth.org/en/permalink/ahliterature122072
Source
Environ Health Perspect. 2012 Oct;120(10):1425-31
Publication Type
Article
Date
Oct-2012
Author
Bonnie R Joubert
Siri E Håberg
Roy M Nilsen
Xuting Wang
Stein E Vollset
Susan K Murphy
Zhiqing Huang
Cathrine Hoyo
Øivind Midttun
Lea A Cupul-Uicab
Per M Ueland
Michael C Wu
Wenche Nystad
Douglas A Bell
Shyamal D Peddada
Stephanie J London
Author Affiliation
Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA.
Source
Environ Health Perspect. 2012 Oct;120(10):1425-31
Date
Oct-2012
Language
English
Publication Type
Article
Keywords
Adult
Basic Helix-Loop-Helix Transcription Factors - genetics - metabolism
Biological Markers - blood
Chromatography, Liquid
Cohort Studies
Cotinine - blood
Cytochrome P-450 CYP1A1 - genetics - metabolism
DNA Methylation
DNA-Binding Proteins - genetics - metabolism
Epigenesis, Genetic
Female
Fetal Blood
Genome-Wide Association Study
Humans
Infant, Newborn
Male
Maternal Exposure
Norway - epidemiology
Pregnancy
Prenatal Exposure Delayed Effects - chemically induced - epidemiology - genetics
Repressor Proteins - genetics - metabolism
Tandem Mass Spectrometry
Tobacco Smoke Pollution - adverse effects
Transcription Factors - genetics - metabolism
United States - epidemiology
Abstract
Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple adverse health outcomes in children, but the underlying mechanisms are unclear.
We investigated epigenome-wide methylation in cord blood of newborns in relation to maternal smoking during pregnancy.
We examined maternal plasma cotinine (an objective biomarker of smoking) measured during pregnancy in relation to DNA methylation at 473,844 CpG sites (CpGs) in 1,062 newborn cord blood samples from the Norwegian Mother and Child Cohort Study (MoBa) using the Infinium HumanMethylation450 BeadChip (450K).
We found differential DNA methylation at epigenome-wide statistical significance (p-value
Notes
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PubMed ID
22851337 View in PubMed
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Abundance and distribution of microplastics in the surface sediments from the northern Bering and Chukchi Seas.

https://arctichealth.org/en/permalink/ahliterature295988
Source
Environ Pollut. 2018 Nov 02; 245:122-130
Publication Type
Journal Article
Date
Nov-02-2018
Author
Jingli Mu
Ling Qu
Fei Jin
Shoufeng Zhang
Chao Fang
Xindong Ma
Weiwei Zhang
Cheng Huo
Yi Cong
Juying Wang
Author Affiliation
Key Laboratory for Ecological Environment in Coastal Areas, State Oceanic Administration, National Marine Environmental Monitoring Center, No. 42, Linghe Street, Dalian, 116023, China; Institute of Oceanography, Minjiang University, No. 200, Wenxian Road, Fuzhou, 350108, China.
Source
Environ Pollut. 2018 Nov 02; 245:122-130
Date
Nov-02-2018
Language
English
Publication Type
Journal Article
Abstract
Worldwide the seafloor has been recognized as a major sink for microplastics. However, currently nothing is known about the sediment microplastic pollution in the North Pacific sector of the Arctic Ocean. Here, we present the first record of microplastic contamination in the surface sediment from the northern Bering and Chukchi Seas. The microplastics were extracted by the density separation method from collected samples. Each particle was identified using the microscopic Fourier transform infrared spectroscopy (µFTIR). The abundances of microplastics in sediments from all sites ranged from not detected (ND) to 68.78 items/kg dry weight (DW) of sediment. The highest level of microplastic contamination in the sediment was detected from the Chukchi Sea. A negative correlation between microplastic abundance and water depth was observed. Polypropylene (PP) accounted for the largest proportion (51.5%) of the identified microplastic particles, followed by polyethylene terephthalate (PET) (35.2%) and rayon (13.3%). Fibers constituted the most common shape of plastic particles. The range of polymer types, physical shapes and spatial distribution characteristics of the microplastics suggest that water masses from the Pacific and local coastal inputs are possible sources for the microplastics found in the study area. In overall, our results highlight the global distribution of these anthropogenic pollutants and the importance of management action to reduce marine debris worldwide.
PubMed ID
30415031 View in PubMed
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Accelerated progression from mild cognitive impairment to dementia among APOE e4e4 carriers.

https://arctichealth.org/en/permalink/ahliterature117987
Source
J Alzheimers Dis. 2013;33(2):507-15
Publication Type
Article
Date
2013
Author
Wei-Li Xu
Barbara Caracciolo
Hui-Xin Wang
Giola Santoni
Bengt Winblad
Laura Fratiglioni
Author Affiliation
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden. weili.xu@ki.se
Source
J Alzheimers Dis. 2013;33(2):507-15
Date
2013
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Alzheimer Disease - genetics - mortality - physiopathology
Apolipoprotein E4 - genetics
Disease Progression
Female
Follow-Up Studies
Genotype
Heterozygote
Humans
Longitudinal Studies
Male
Mild Cognitive Impairment - genetics - mortality - physiopathology
Proportional Hazards Models
Risk factors
Sweden - epidemiology
Abstract
The impact of APOE e4 on mild cognitive impairment (MCI) and its progression to dementia remain controversial. We aimed to examine the association of APOE e4 with MCI, and to verify the hypothesis that e4 accelerates progression from MCI to dementia. In the Kungsholmen project, 756 cognitively healthy participants and 212 people with MCI aged =75 years were identified at baseline. Amnestic MCI (aMCI) and other cognitive impairment no dementia (oCIND) as two subtypes of MCI were assessed based on standard definitions. The two cohorts were followed for 9 years to detect incident cases of MCI and dementia following international criteria. APOE genotypes were assessed at baseline. Data were analyzed using Cox models. During the follow-up, in the cognitively healthy cohort, 165 people developed MCI (40 aMCI and 125 oCIND) and 176 developed dementia; in the MCI cohort, 118 persons progressed to dementia. Compared with APOE e3e3, the hazard ratios (HRs) (95% CIs) of e2e4/e3e4 were 2.24 (1.10-4.57) for aMCI and 1.78 (1.15-2.75) for oCIND, while the e4e4 was related to dementia with a HR of 4.35 (1.97-9.63) in the cognitively healthy cohort. In the MCI cohort, the e4e4 genotype led to a multi-adjusted HR of 2.89 (1.12-7.48) for dementia and accelerated the progression to dementia by 3.36 years. The APOE e4 heterozygotes are associated with an increased risk of aMCI and oCIND. The e4 homozygote substantially accelerates progression from MCI to dementia, and anticipate dementia occurrence by more than 3 years in people with MCI.
PubMed ID
23247007 View in PubMed
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Acceleration of global vegetation greenup from combined effects of climate change and human land management.

https://arctichealth.org/en/permalink/ahliterature292666
Source
Glob Chang Biol. 2018 Jul 02; :
Publication Type
Journal Article
Date
Jul-02-2018
Author
Lanhui Wang
Feng Tian
Yuhang Wang
Zhendong Wu
Guy Schurgers
Rasmus Fensholt
Author Affiliation
Department of Geosciences and Natural Resource Management, University of Copenhagen, Øster Voldgade 10, DK-1350, Copenhagen, Denmark.
Source
Glob Chang Biol. 2018 Jul 02; :
Date
Jul-02-2018
Language
English
Publication Type
Journal Article
Abstract
Global warming and human land management have greatly influenced vegetation growth through both changes in spring phenology and photosynthetic primary production. This will presumably impact the velocity of vegetation greenup (Vgreenup, the daily rate of changes in vegetation productivity during greenup period), yet little is currently known about the spatio-temporal patterns of Vgreenup of global vegetation. Here, we define Vgreenup as the ratio of the amplitude of greenup (Agreenup) to the duration of greenup (Dgreenup) and derive global Vgreenup from 34-year satellite leaf area index (LAI) observations to study spatio-temporal dynamics of Vgreenup at the global, hemispheric and ecosystem scales. We find that 19.9% of the pixels analyzed (n = 1175453) experienced significant trends toward higher greenup rates by an average of 0.018 m2 m-2 day-1 for 1982-2015 as compared to 8.6% of pixels with significant negative trends (P
PubMed ID
29963745 View in PubMed
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Acceleration of global vegetation greenup from combined effects of climate change and human land management.

https://arctichealth.org/en/permalink/ahliterature297897
Source
Glob Chang Biol. 2018 11; 24(11):5484-5499
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
11-2018
Author
Lanhui Wang
Feng Tian
Yuhang Wang
Zhendong Wu
Guy Schurgers
Rasmus Fensholt
Author Affiliation
Department of Geosciences and Natural Resource Management, University of Copenhagen, Copenhagen, Denmark.
Source
Glob Chang Biol. 2018 11; 24(11):5484-5499
Date
11-2018
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Agriculture
Climate change
Forestry
Humans
Plant Development
Remote Sensing Technology
Urbanization
Abstract
Global warming and human land management have greatly influenced vegetation growth through both changes in spring phenology and photosynthetic primary production. This will presumably impact the velocity of vegetation greenup (Vgreenup, the daily rate of changes in vegetation productivity during greenup period), yet little is currently known about the spatio-temporal patterns of Vgreenup of global vegetation. Here, we define Vgreenup as the ratio of the amplitude of greenup (Agreenup) to the duration of greenup (Dgreenup) and derive global Vgreenup from 34-year satellite leaf area index (LAI) observations to study spatio-temporal dynamics of Vgreenup at the global, hemispheric, and ecosystem scales. We find that 19.9% of the pixels analyzed (n = 1,175,453) experienced significant trends toward higher greenup rates by an average of 0.018 m2  m-2  day-1 for 1982-2015 as compared to 8.6% of pixels with significant negative trends (p 
PubMed ID
29963745 View in PubMed
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Accuracy of self-reported anthropometric measures - Findings from the Finnish Twin Study.

https://arctichealth.org/en/permalink/ahliterature308022
Source
Obes Res Clin Pract. 2019 Nov - Dec; 13(6):522-528
Publication Type
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Twin Study
Author
J Tuomela
J Kaprio
P N Sipilä
K Silventoinen
X Wang
M Ollikainen
M Piirtola
Author Affiliation
Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, PO Box 20, Helsinki, FI-00014, Finland; Finnish Gymnastics Federation, Hämeentie 105 A, 00550 Helsinki, Finland. Electronic address: jenni.tuomela@voimistelu.fi.
Source
Obes Res Clin Pract. 2019 Nov - Dec; 13(6):522-528
Language
English
Publication Type
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Twin Study
Keywords
Age Factors
Aged
Anthropometry
Body constitution
Body Height
Body mass index
Body Weight
Cohort Studies
Female
Finland
Humans
Male
Middle Aged
Obesity
Reproducibility of Results
Self Report
Sex Factors
Twins, Dizygotic - statistics & numerical data
Twins, Monozygotic - statistics & numerical data
Waist Circumference
Abstract
To determine the accuracy of self-reported height, weight, body mass index (BMI) and waist circumference (WC) compared to the measured values, and to assess the similarity between self-reported and measured values within dizygotic (DZ) and monozygotic (MZ) twin pairs.
The data on self-reported and measured height, weight and WC values as well as measured hip circumference (HC) were collected from 444 twin individuals (53-67 years old, 60% women). Accuracies between self-reported and measured values were assessed by Pearson's correlation coefficients, Cohen's kappa coefficients and Bland-Altman 95% limits of agreement. Intra-class correlation was used in within-pair analyses.
The correlations between self-reported and measured values were high for all variables (r=0.86-0.98), although the agreement assessed by Bland-Altman 95% limits had relatively wide variation. The degree of overestimating height was similar in both sexes, whereas women tended to underestimate and men overestimate their weight. Cohen's kappa coefficients between self-reported and measured BMI categories were high: 0.71 in men and 0.70 in women. Further, the mean self-reported WC was less than the mean measured WC (difference in men 2.5cm and women 2.6cm). The within-pair correlations indicated a tendency of MZ co-twins to report anthropometric measures more similarly than DZ co-twins.
Self-reported anthropometric measures are reasonably accurate indicators for obesity in large cohort studies. However, the possibility of more similar reporting among MZ pairs should be taken into account in twin studies exploring the heritability of different phenotypes.
PubMed ID
31761633 View in PubMed
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1439 records – page 1 of 144.