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[Continuous cell subline A4C2/9K and its application to the african swine fever virus study].

https://arctichealth.org/en/permalink/ahliterature265334
Source
Vopr Virusol. 2015;60(2):43-7
Publication Type
Article
Date
2015
Author
V I Balysheva
E Yu Prudnikova
T V Galnbek
V M Balyshev
Source
Vopr Virusol. 2015;60(2):43-7
Date
2015
Language
Russian
Publication Type
Article
Keywords
African Swine Fever - immunology
African Swine Fever Virus - growth & development - immunology - pathogenicity
Animals
Cell Line - cytology - virology
Russia
Swine
Abstract
A new continuous cell subline A4C2/9K highly sensitive to the african swine fever virus (ASFV) was prepared. All the tested ASFV strains isolated in the Russian Federation in 2008-2013 proliferated in this cell culture exhibiting hemadsorption and accumulated at a titer of up to 6.5 Ig HAU50/cm3. The cell culture A4C2/9K can be used for ASFV isolation or determination of its infectious activity and serotype identity. The culture versions of the ASFV strain Stavropol 01/08 at passages 24 and 33 in the cell culture A4C2/9K lost their pathogenicity for pigs.
PubMed ID
26182658 View in PubMed
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