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[Administration of essential phospholipids in persons exposed to chemical industrial pollutants].

https://arctichealth.org/en/permalink/ahliterature180414
Source
Ter Arkh. 2004;76(2):63-6
Publication Type
Article
Date
2004
Author
L A Shpagina
S V Bobrov
Source
Ter Arkh. 2004;76(2):63-6
Date
2004
Language
Russian
Publication Type
Article
Keywords
Antioxidants - administration & dosage - therapeutic use
Hazardous Substances - poisoning
Humans
Liver Function Tests
Occupational Diseases - drug therapy - etiology
Occupational Exposure - adverse effects
Phosphatidylcholines - administration & dosage - therapeutic use
Poisoning - drug therapy - etiology
Russia
Treatment Outcome
Abstract
To examine efficacy of the drug essliver-forte in patients with chronic intoxication by a complex of such toxicants as soluble and unsoluble compounds of uranium, lead and mercury.
The examination of bilirubin, synthesis of proteins and enzyme production by the liver, activity of free radical lipid oxidation and antioxidant defence was conducted in 42 persons (mean age 66.4 +/- 4.2 years) occupationally exposed to chemicals (compounds of uranium, lead and mercury) for 12.6 +/- 1.8 years. The patients were divided into two equal groups: patients of group 1 received standard therapy with enterosorbents, cerebral angioprotectors and alpha-tocopherol; patients of group 2 instead of alpha-tocopherol were given essliver-forte (2 capsules twice a day).
Patients of group 2 had significantly less frequent complaints for fatigue, anxiety, dyspnea, sleep disorders; improvement was observed in peripheral blood counts, in concentrations of alpha 2- and gamma-globulins, sulfhydril and catalase activity of erythrocytes; transaminase activity and intensity of saponin hemolysis went down.
Essliver-forte is effective in persons occupationally exposed to chemicals.
PubMed ID
15106419 View in PubMed
Less detail

[Efficiency of early diagnosis and prevention of chronic obstructive pulmonary disease in industrial workers (prospective observation results)].

https://arctichealth.org/en/permalink/ahliterature128024
Source
Med Tr Prom Ekol. 2011;(10):6-10
Publication Type
Article
Date
2011
Author
S V Bobrov
L A Shpagina
G V Kuznetsova
M R Burganova
Source
Med Tr Prom Ekol. 2011;(10):6-10
Date
2011
Language
Russian
Publication Type
Article
Keywords
Adult
Aerosols - adverse effects
Early Diagnosis
Follow-Up Studies
Humans
Industry - statistics & numerical data
Middle Aged
Nuclear Reactors
Occupational Exposure - adverse effects
Occupational Health
Prevalence
Program Evaluation
Prospective Studies
Pulmonary Disease, Chronic Obstructive - diagnosis - epidemiology - physiopathology - psychology
Risk
Russia
Smoking
Stress, Psychological - epidemiology - prevention & control
Abstract
Examination of workers engaged into major industrial enterprises of Novosibirsk demonstrated high prevalence of bronchial obstruction in individuals contacting industrial aerosol. The workers with long length of service proved high level of tobacco addiction and marked psychologic dependence on smoking. Based on the data obtained, the authors specified a program for early diagnosis and prevention of occupational bronchitis among the workers of major industrial enterprises.
PubMed ID
22242276 View in PubMed
Less detail

[Risk factors and rehabilitation of workers with COPD in major industrial enterprise].

https://arctichealth.org/en/permalink/ahliterature152835
Source
Med Tr Prom Ekol. 2008;(11):11-5
Publication Type
Article
Date
2008
Author
S V Bobrov
G V Kuznetsova
N V Liulina
M S Zhelezniak
Source
Med Tr Prom Ekol. 2008;(11):11-5
Date
2008
Language
Russian
Publication Type
Article
Keywords
Adult
Bronchodilator Agents - therapeutic use
Female
Humans
Industry - statistics & numerical data
Male
Middle Aged
Occupational Diseases - epidemiology - rehabilitation
Prevalence
Pulmonary Disease, Chronic Obstructive - epidemiology - etiology - rehabilitation
Risk factors
Russia - epidemiology
Abstract
The authors present epidemiologic characteristics of COLD in workers of major atomic machinery enterprise. The article covers high prevalence of this disease on the enterprise, evaluation of connection between occupational and non-occupational risk factors and COLD development. Constant broncholytic therapy in the occupational health office caused significant improvement of clinical and functional parameters and decrease in transitory disablement duration.
PubMed ID
19186530 View in PubMed
Less detail

[State of vascular-platelet hemostasis and plasma-coagulation hemostasis in patients with occupational bronchitis and workers under high occupational risk].

https://arctichealth.org/en/permalink/ahliterature140489
Source
Med Tr Prom Ekol. 2010;(8):10-3
Publication Type
Article
Date
2010
Author
L A Shpagina
M V Vlasenko
S V Bobrov
Source
Med Tr Prom Ekol. 2010;(8):10-3
Date
2010
Language
Russian
Publication Type
Article
Keywords
Aerosols
Blood Coagulation - physiology
Blood Platelets - cytology
Bronchitis - blood - complications - epidemiology - physiopathology
Dust
Endothelium, Vascular - physiopathology
Humans
Middle Aged
Occupational Diseases - blood - complications - epidemiology - physiopathology
Occupational Exposure - adverse effects
Platelet Aggregation - physiology
Platelet Count
Respiratory Insufficiency - blood - epidemiology - etiology - physiopathology
Risk
Siberia
Abstract
Evaluation of various hemostasis subunits helps to specify mechanisms underlying influence of industrial aerosol on respiratory tract. The most important events are changes in vascular and platelet hemostasis, fibrinolysis system in individuals exposed to highly fibrogenic dust.
PubMed ID
20873253 View in PubMed
Less detail