The results of examination of 87 children who died from a generalized cytomegalovirus infection in Elista (66 cases) in 1984-1985, 1988-89, and in Leningrad (21 cases) in 1988-89 are available. In the Elista material a considerable increase (from 21 to 66%) of severe forms of accidental transformation of thymus is observed in the second period comparing to the first one. The causes of a serious worsening of the immunological background remain unclear. Cytomegaly represented 3.85% of all dead children in the pathology department of the First Children Hospital of Leningrad. There was sialadenitis in 4 cases and generalized infection with involvement of the lungs, liver, kidneys, brain, myocardium, pancreas, adrenals in 17 cases. Cytomegaly was diagnosed in 3 of 5 cases of primary immunodeficiency. Diagnosis in some cases was confirmed by the DNA cytomegalovirus detection by means of PCR reaction.
The article touches upon problems of the improvement of transfusiological maintenance of surgical departments with new tendencies in the donor movement taken into account. Specific methods to gain this aim are proposed.