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Breast cancer and clinical outcome among women over 60 years of age: a plead for more screening and alternative treatments.

https://arctichealth.org/en/permalink/ahliterature120327
Source
Anal Quant Cytopathol Histpathol. 2012 Aug;34(4):189-94
Publication Type
Article
Date
Aug-2012
Author
Roland B Sennerstam
Hans Wiksell
Kai-Uwe Schässburger
Gert U Auer
Author Affiliation
Departments of Oncology and Pathology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden. roland.sennerstam@ki.se
Source
Anal Quant Cytopathol Histpathol. 2012 Aug;34(4):189-94
Date
Aug-2012
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Breast Neoplasms - epidemiology - pathology - radiography
Early Detection of Cancer
Female
Humans
Mammography
Middle Aged
Neoplasm Grading
Neoplasm Staging
Sweden - epidemiology
Treatment Outcome
Abstract
To study elderly women > or = 60 years of age diagnosed with breast cancer and analyze this cohort according to death from breast cancer and death due to comorbidities. Patients aged 60-69 years of age were included in routine mammography screening, but not women aged > or = 70 years. This enabled a comparison between the 2 groups regarding screening effect, tumor size and survival in breast cancer.
A consecutive sample of 311 breast cancer patients > or = 60 years of age from 1991 were analyzed according to tumor size at diagnosis, frequencies of lymph node metastasis, tumor histological grade and stage, ploidy, proliferation index, stem-line-scatter index and survival rate in breast cancer and other causes of death. Tumor size was compared to a patient group aged 60-69 from 1987, before the introduction of mammography screening in Sweden.
In the screening group a significant reduction in tumor size was found at diagnosis compared to the sample from 1987 (p or = 70 years (p
PubMed ID
23016465 View in PubMed
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