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Acute stroke unit care combined with early supported discharge. Long-term effects on quality of life. A randomized controlled trial.

https://arctichealth.org/en/permalink/ahliterature45787
Source
Clin Rehabil. 2004 Aug;18(5):580-6
Publication Type
Article
Date
Aug-2004
Author
Hild Fjaertoft
Bent Indredavik
Roar Johnsen
Stian Lydersen
Author Affiliation
Department of Neuroscience and Motion, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. hild.fjartoft@medisin.ntnu.no
Source
Clin Rehabil. 2004 Aug;18(5):580-6
Date
Aug-2004
Language
English
Publication Type
Article
Keywords
Aged
Cerebrovascular Accident - rehabilitation
Continuity of Patient Care
Early Ambulation
Female
Follow-Up Studies
Home Care Services - organization & administration
Hospital Units - organization & administration
Humans
Male
Norway
Patient care team
Patient Discharge
Quality of Life
Questionnaires
Research Support, Non-U.S. Gov't
Abstract
OBJECTIVES: The aim of the present trial was to compare the effects of an extended stroke unit service (ESUS) with the effects of an ordinary stroke unit service (OSUS) on long-term quality of life (QoL). DESIGN: One year follow-up of a randomized controlled trial with 320 acute stroke patients allocated either to OSUS (160 patients) or ESUS (160 patients) with early supported discharge and follow-up by a mobile team. The intervention was a mobile team and close co-operation with the primary health care service. All assessments were blinded. MAIN OUTCOME MEASURE: Primary outcome of QoL in this paper was measured by the Nottingham Health Profile (NHP) at 52 weeks. Secondary outcomes measured at 52 weeks were differences between the groups measured by the Frenchay Activity Index, Montgomery-Asberg Depression Scale, Mini-Mental State Score and the Caregivers Strain Index. RESULTS: The ESUS group had a significantly better QoL (mean score 78.9) assessed by global NHP after one year than the OSUS group (mean score 75.2) (p =0.048). There were no significant differences between the groups in the secondary outcomes, but a trend in favour of ESUS. Caregivers Strain Index showed a mean score of 23.3 in the ESUS group and 22.6 in the OSUS group (p=0.089). CONCLUSION: It seems that stroke unit treatment combined with early supported discharge in addition to reducing the length of hospital stay can improve long-term QoL. However, similar trials are necessary to confirm the benefit of this type of service.
PubMed ID
15293492 View in PubMed
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Adolescent health and high school dropout: a prospective cohort study of 9000 Norwegian adolescents (the Young-HUNT).

https://arctichealth.org/en/permalink/ahliterature106925
Source
PLoS One. 2013;8(9):e74954
Publication Type
Article
Date
2013
Author
Karin A A De Ridder
Kristine Pape
Roar Johnsen
Turid Lingaas Holmen
Steinar Westin
Johan Håkon Bjørngaard
Author Affiliation
Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway ; Department of Physical Medicine and Rehabilitation, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, Norway.
Source
PLoS One. 2013;8(9):e74954
Date
2013
Language
English
Publication Type
Article
Keywords
Adolescent
Cluster analysis
Family
Female
Health status
Humans
Logistic Models
Male
Norway - epidemiology
Odds Ratio
Prospective Studies
Schools
Student Dropouts - statistics & numerical data
Young Adult
Abstract
High school dropout is of major concern in the western world. Our aims were to estimate the risk of school dropout in adolescents following chronic somatic disease, somatic symptoms, psychological distress, concentration difficulties, insomnia or overweight and to assess to which extent the family contributes to the association between health and school dropout.
A population of 8950 school-attending adolescents (13-21 years) rated their health in the Young-HUNT 1 Study (90% response rate) in 1995-1997. High school dropout or completion, was defined with the Norwegian National Education Database in the calendar year the participant turned 24 years old. Parental socioeconomic status was defined by using linkages to the National Education Database, the National Insurance Administration and the HUNT2 Survey. We used logistic regression to estimate odds ratios and risk differences of high school dropout, both in the whole population and among siblings within families differentially exposed to health problems.
All explored health dimensions were strongly associated with high school dropout. In models adjusted for parental socioeconomic status, the risk differences of school dropout according to health exposures varied between 3.6% (95% CI 1.7 to 5.5) for having = 1 somatic disease versus none and 11.7% (6.3 to 17.0) for being obese versus normal weight. The results from the analyses comparing differentially exposed siblings, confirmed these results with the exception of weaker associations for somatic diseases and psychological distress. School dropout was strongly clustered within families (family level conditional intraclass correlation 0.42).
Adolescent health problems are markers for high school dropout, independent of parental socioeconomic status. Although school dropout it strongly related to family-level factors, also siblings with poor health have reduced opportunity to complete high school compared to healthy siblings. Public health policy should focus on ensuring young people with poor health the best attainable education.
Notes
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PubMed ID
24086408 View in PubMed
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Adolescent respiratory symptoms--girls are at risk: the Young-HUNT study, Norway.

https://arctichealth.org/en/permalink/ahliterature15033
Source
Respir Med. 2006 Mar;100(3):471-6
Publication Type
Article
Date
Mar-2006
Author
Elin Tollefsen
Leif Bjermer
Arnulf Langhammer
Roar Johnsen
Turid Lingaas Holmen
Author Affiliation
Department of Pulmonary Medicine, St. Olav's University Hospital, Trondheim, Norway. elin.tollefsen@ntnu.no
Source
Respir Med. 2006 Mar;100(3):471-6
Date
Mar-2006
Language
English
Publication Type
Article
Abstract
The objective was to study sex differences in adolescence regarding prevalence of asthma and current wheeze and to explore the association between respiratory symptoms and hereditary, lifestyle and socioeconomic factors. Young-HUNT included data comprehensive questionnaire on health, disease, lifestyle and social factors from 8817 teenagers 13-19 years conducted in 1995/97 (89% response rate). Questionnaire on respiratory symptoms was based on the International Study of Asthma and Allergy in Childhood (ISAAC). In age groups 13-16 and 17-19 years, current wheeze was reported by 29.0% and 33.5% among girls and 20.4% and 22.1% among boys, whilst the corresponding figures for asthma were 8.5% and 12.2% among girls and 7.1% and 7.0% among boys. Both wheeze and asthma were significantly more prevalent and increased with age in girls compared to boys. Heredity was associated with asthma, but the association was strongest between parents and children of the same sex. Environmental smoking was associated with asthma and wheeze in girls only. Girls reported more asthma and wheeze in association with overweight compared to boys. Girls reported more wheeze and asthma than boys and seemed more susceptible to risk factors such as environmental smoking and overweight than boys. Moreover, girls with mothers having asthma were more likely to be diagnosed as asthmatics themselves.
PubMed ID
16039839 View in PubMed
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Assessing atopic disease in children two to six years old: reliability of a revised questionnaire.

https://arctichealth.org/en/permalink/ahliterature158247
Source
Prim Care Respir J. 2008 Sep;17(3):164-8
Publication Type
Article
Date
Sep-2008
Author
Torbjørn Øien
Ola Storrø
Roar Johnsen
Author Affiliation
Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway. torbjorn.oien@ntnu.no
Source
Prim Care Respir J. 2008 Sep;17(3):164-8
Date
Sep-2008
Language
English
Publication Type
Article
Keywords
Asthma - diagnosis
Case-Control Studies
Child
Child, Preschool
Conjunctivitis - diagnosis
Eczema - diagnosis
Feasibility Studies
Focus Groups
Humans
Pilot Projects
Questionnaires
Reproducibility of Results
Rhinitis - diagnosis
Abstract
Primary intervention - reducing second hand smoking (SHS), indoor dampness, and increased intake of omega-3-fatty acids - for allergic diseases such as asthma, rhinoconjunctivitis, and eczema/dermatitis in children was started in Trondheim in 2002. To our knowledge, no validated or reliable questionnaires for the study age groups were available.
To test the reliability of a revised questionnaire for studying atopic disease in children two to six years old in Trondheim.
Seventy-seven families were invited to fill in a questionnaire adapted from the ISAAC protocol which was made appropriate for the age group studied. Completed questionnaires and information from medical records were compared, and the agreement was analysed by Kappa statistics and proportional agreement.
Agreement was excellent for questions reporting current information such as doctor-diagnosed asthma (kappa=0.88), whether or not the child had had an allergy test (kappa=0.82), and use of antibiotics (kappa=0.81). The agreement was good for questions concerning doctor or hospital treatment for asthma (kappa=0.59), medication for asthma (kappa=0.58), symptoms of eczema (kappa=0.56), medication for allergic disease (kappa=0.45), and past infections (kappa=0.53).
Questions on asthma diagnosis, allergy testing, and use of antibiotics were reliable. Questions on medical treatment for eczema, allergic rhinoconjunctivitis and infections were less reliable, representing a potential source of information bias and possible misclassification.
PubMed ID
18345462 View in PubMed
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Atopic dermatitis prevention in children following maternal probiotic supplementation does not appear to be mediated by breast milk TSLP or TGF-ß.

https://arctichealth.org/en/permalink/ahliterature274779
Source
Clin Transl Allergy. 2016;6:27
Publication Type
Article
Date
2016
Author
Melanie Rae Simpson
Anne Dorthea Bjerkenes Rø
Øystein Grimstad
Roar Johnsen
Ola Storrø
Torbjørn Øien
Source
Clin Transl Allergy. 2016;6:27
Date
2016
Language
English
Publication Type
Article
Abstract
The Probiotics in Prevention of Allergy among Children in Trondheim (ProPACT) study, a randomised, placebo controlled trial, demonstrated that maternal supplementation with probiotic milk reduced the incidence of atopic dermatitis (AD) in infancy. The mechanisms behind this effect are incompletely understood and breast milk cytokines have been postulated as possible mediating factors. In this study we aimed to assess whether breast milk TLSP and TGF-ß are affected by a maternal probiotic supplementation regime, and their contribution to the preventive effect of this regime on AD in the offspring.
TSLP and TGF-ß isoforms (TGF-ß1, TGF-ß2 and TGF-ß3) were measured using ELISA and multiplex assays, respectively, in breast milk samples collected at 10 days and 3 months postpartum from women participating in the ProPACT trial (n = 259). The natural indirect and direct effects of maternal probiotics on AD, due to changes in breast milk cytokines, were estimated using causal mediation techniques.
Probiotic supplementation tend to lead to high levels of breast milk TSLP at 10 days postpartum (p = 0.062), but this change did not contribute to the prevention of AD according to the mediation analysis. Probiotics had no apparent effect on TSLP at 3 months or TGF-ßs at either time points. Thus, these are unlikely to be mediators of the effect of maternal probiotics on AD in offspring.
Whilst maternal probiotic supplementation resulted in higher breast milk concentrations of TLSP at 10 days postpartum, this does not appear to be a mechanism for prevention of AD by maternal probiotics. Trial registration The original trial protocol is registered in ClinicalTrials.gov (identifier NCT00159523).
PubMed ID
27453775 View in PubMed
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Attitudes towards sickness absence and sickness presenteeism in health and care sectors in Norway and Denmark: a qualitative study.

https://arctichealth.org/en/permalink/ahliterature265224
Source
BMC Public Health. 2014;14:880
Publication Type
Article
Date
2014
Author
Line Krane
Eva Ladekjær Larsen
Claus Vinther Nielsen
Christina Malmose Stapelfeldt
Roar Johnsen
Mette Bech Risør
Source
BMC Public Health. 2014;14:880
Date
2014
Language
English
Publication Type
Article
Keywords
Absenteeism
Adult
Aged
Attitude of Health Personnel
Denmark
Female
Humans
Male
Middle Aged
Norway
Nursing Homes
Occupational Health Services
Rural Population
Sick Leave
Urban Population
Workplace
Abstract
In the health and care sector, sickness absence and sickness presenteeism are frequent phenomena and constitute a field in need of exploration. Attitudes towards sickness absence involve also attitudes towards sickness presenteeism, i.e. going to work while sick, confirmed by previous studies. Sickness behavior, reflecting attitudes on work absence, could differ between countries and influence absence rates. But little is known about attitudes towards sickness absence and sickness presenteeism in the health and care sectors in Norway and Denmark. The aim of the present paper is therefore to explore attitudes towards sickness absence and sickness presenteeism among nursing home employees in both countries.
Eight focus group discussions (FGDs) were conducted using a semi-structured interview guide, the main attention of which was attitudes towards sickness absence and sickness presenteeism. FGDs were conducted in two nursing homes in Norway and two in Denmark, with different geographic locations: one in a rural area and one in an urban area in each country. FGDs were recorded, transcribed and analyzed using framework analysis to identify major themes and explanatory patterns.
Four major significant themes were identified from the FGDs: a) sickness absence and sickness presenteeism, b) acceptable causes of sickness absence, c) job identity, and d) organization of work and physical aspects of the workplace. Our analyses showed that social commitment and loyalty to residents and colleagues was important for sickness absence and sickness presenteeism, as were perceived acceptable and non-acceptable reasons for sickness absence. Organization of work and physical aspects of the workplace were also found to have an influence on attitudes towards sickness absence.
The general interpretation of the findings was that attitudes towards sickness absence and sickness presenteeism among nursing home employees were embedded in situational patterns of moral relationships and were connected to a specific job identity. These patterns were constituted by the perception of colleagues, the social commitment to residents, and they influence on what was deemed as acceptable and non-acceptable reasons for sickness absence. In other words, attitudes towards sickness absence and sickness presenteeism were socially and morally determined at personal levels by an overall concept of work, independent of country.
Notes
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PubMed ID
25160059 View in PubMed
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Breastfeeding-associated microbiota in human milk following supplementation with Lactobacillus rhamnosus GG, Lactobacillus acidophilus La-5, and Bifidobacterium animalis ssp. lactis Bb-12.

https://arctichealth.org/en/permalink/ahliterature294185
Source
J Dairy Sci. 2018 Feb; 101(2):889-899
Publication Type
Journal Article
Date
Feb-2018
Author
Melanie Rae Simpson
Ekaterina Avershina
Ola Storrø
Roar Johnsen
Knut Rudi
Torbjørn Øien
Author Affiliation
Department of Public Health and Nursing, NTNU - Norwegian University of Science and Technology, N-7030 Trondheim, Norway. Electronic address: melanie.simpson@ntnu.no.
Source
J Dairy Sci. 2018 Feb; 101(2):889-899
Date
Feb-2018
Language
English
Publication Type
Journal Article
Keywords
Adult
Bacteria - classification
Bifidobacterium animalis - chemistry
Breast Feeding
Dermatitis, Atopic - epidemiology
Female
Humans
Incidence
Lactobacillus acidophilus - chemistry
Lactobacillus rhamnosus - chemistry
Microbiota
Milk, Human - microbiology
Norway - epidemiology
Postpartum Period
Probiotics - administration & dosage
Abstract
Breastfeeding is one of the major factors affecting the early development of the infant gut microbiota, and weaning is associated with a shift in the gut microbiota toward a more adult composition. Through breastfeeding, infants receive bioactive components that shape their microbiota while also being exposed to the breast milk and breast surface microbial communities. Recent studies have suggested the possibility of an entero-mammary route of microbial transfer, opening the possibility of infant gut microbiota modulation through maternal probiotic supplementation. In this study, we have analyzed breast milk samples collected at 10 d and 3 mo postpartum from women participating in the Probiotics in the Prevention of Allergy among Children in Trondheim placebo controlled trial. Women who were randomized to the probiotic arm of the Probiotics in the Prevention of Allergy among Children in Trondheim trial received a fermented milk supplemented with Lactobacillus rhamnosus GG, Lactobacillus acidophilus La-5, and Bifidobacterium animalis ssp. lactis Bb-12, consuming this daily from 4 wk before their expected due date until 3 mo after birth. In total, 472 breast milk samples were assessed for the administered bacteria using quantitative real-time PCR and the microbiota transferred during breastfeeding was analyzed using 16S ribosomal RNA gene sequencing of 142 samples. We found that breastfeeding is unlikely to be a significant source of L. rhamnosus GG, L. acidophilus La-5, and B. animalis ssp. lactis Bb-12 for infants in the probiotic arm of the trial. Furthermore, maternal supplementation did not significantly affect the overall composition of the breast milk microbiota transferred during breastfeeding. We also present a descriptive analysis of this microbiota, which was largely dominated by Streptococcus and Staphylococcus genera at both 10 d and 3 mo postpartum. Samples collected at 3 mo postpartum had a statistically significant lower presence and relative abundance of the Staphylococcus genus. These samples also had a greater number of observed species and diversity, including more operational taxonomic units from the Rothia, Veillonella, Granulicatella, and Methylbacterium genera.
PubMed ID
29248229 View in PubMed
Less detail

Breastfeeding-associated microbiota in human milk following supplementation with Lactobacillus rhamnosus GG, Lactobacillus acidophilus La-5, and Bifidobacterium animalis subspecies lactis Bb-12.

https://arctichealth.org/en/permalink/ahliterature287764
Source
J Dairy Sci. 2017 Dec 13;
Publication Type
Article
Date
Dec-13-2017
Author
Melanie Rae Simpson
Ekaterina Avershina
Ola Storrø
Roar Johnsen
Knut Rudi
Torbjørn Øien
Source
J Dairy Sci. 2017 Dec 13;
Date
Dec-13-2017
Language
English
Publication Type
Article
Abstract
Breastfeeding is one of the major factors affecting the early development of the infant gut microbiota, and weaning is associated with a shift in the gut microbiota toward a more adult composition. Through breastfeeding, infants receive bioactive components that shape their microbiota while also being exposed to the breast milk and breast surface microbial communities. Recent studies have suggested the possibility of an entero-mammary route of microbial transfer, opening the possibility of infant gut microbiota modulation through maternal probiotic supplementation. In this study, we have analyzed breast milk samples collected at 10 d and 3 mo postpartum from women participating in the Probiotics in the Prevention of Allergy among Children in Trondheim placebo controlled trial. Women who were randomized to the probiotic arm of the Probiotics in the Prevention of Allergy among Children in Trondheim trial received a fermented milk supplemented with Lactobacillus rhamnosus GG, Lactobacillus acidophilus La-5, and Bifidobacterium animalis ssp. lactis Bb-12, consuming this daily from 4 wk before their expected due date until 3 mo after birth. In total, 472 breast milk samples were assessed for the administered bacteria using quantitative real-time PCR and the microbiota transferred during breastfeeding was analyzed using 16S ribosomal RNA gene sequencing of 142 samples. We found that breastfeeding is unlikely to be a significant source of L. rhamnosus GG, L. acidophilus La-5, and B. animalis ssp. lactis Bb-12 for infants in the probiotic arm of the trial. Furthermore, maternal supplementation did not significantly affect the overall composition of the breast milk microbiota transferred during breastfeeding. We also present a descriptive analysis of this microbiota, which was largely dominated by Streptococcus and Staphylococcus genera at both 10 d and 3 mo postpartum. Samples collected at 3 mo postpartum had a statistically significant lower presence and relative abundance of the Staphylococcus genus. These samples also had a greater number of observed species and diversity, including more operational taxonomic units from the Rothia, Veillonella, Granulicatella, and Methylbacterium genera.
PubMed ID
29248229 View in PubMed
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Changes among male and female visitors to practitioners of complementary and alternative medicine in a large adult Norwegian population from 1997 to 2008 (The HUNT studies).

https://arctichealth.org/en/permalink/ahliterature132274
Source
BMC Complement Altern Med. 2011;11:61
Publication Type
Article
Date
2011
Author
Aslak Steinsbekk
Marit B Rise
Roar Johnsen
Author Affiliation
Norwegian University of Science and Technology, Department of Public Health and General Practice, Trondheim, Norway. aslak.steinsbekk@ntnu.no
Source
BMC Complement Altern Med. 2011;11:61
Date
2011
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Chiropractic - utilization
Chronic Disease - therapy
Complementary Therapies - trends - utilization
Cross-Sectional Studies
Educational Status
Female
Health Care Surveys
Health status
Humans
Logistic Models
Male
Mental Disorders - therapy
Norway
Physical Exertion
Rhinitis, Allergic, Seasonal - therapy
Sex Factors
Widowhood
Abstract
The aim was to investigate changes in the prevalence and characteristics of male and female visitors to practitioners of complementary and alternative medicine (CAM) in a large adult population from 1997 to 2008.
Two cross sectional adult total population health surveys from Central Norwegian (the Nord-Trøndelag Health Studies (HUNT)). In 1997 42,277 and in 2008 50,713 respondents were included. Variables included demographics (age, education, working status), lifestyle (daily smoker, did hard physical activities), health status (self-rated health status, recent complaints, chronic complaints, psychiatric complaints, a range of diseases) and health care use (visit general practitioner, chiropractor). A test of difference between the results of multivariable logistic regression models for each year, including all variables, was used to analyse changes from 1997 to 2008.
In 1997 9.4% (95%CI 9.1-9.6) of the population had visited a CAM practitioner in the last 12 months and this increased to 12.6% (12.3-12.9) in 2008 (p
Notes
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PubMed ID
21835013 View in PubMed
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Comparison of sick leave patterns between Norway and Denmark in the health and care sector: a register study.

https://arctichealth.org/en/permalink/ahliterature113133
Source
Scand J Public Health. 2013 Nov;41(7):684-91
Publication Type
Article
Date
Nov-2013
Author
Line Krane
Nils Fleten
Christina M Stapelfeldt
Claus Vinther Nielsen
Chris Jensen
Roar Johnsen
Tonje Braaten
Author Affiliation
1Department of Community Medicine/University of Tromsø, Norway.
Source
Scand J Public Health. 2013 Nov;41(7):684-91
Date
Nov-2013
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Aged
Denmark
Employment - statistics & numerical data
Female
Health Care Sector - statistics & numerical data
Humans
Middle Aged
Norway
Occupations - statistics & numerical data
Registries
Sick Leave - statistics & numerical data
Women, Working - statistics & numerical data
Young Adult
Abstract
Sickness absence is of considerable concern in both Norway and Denmark. Labour Force Surveys indicate that absence in Norway is about twice that in Denmark and twice that of the mean reported by the Organisation for Economic Co-operation and Development. This study compares absence patterns according to age, percentage of employment, and occupation between municipal employees in the health and care sectors in two municipalities in Norway and Denmark.
Data recorded in the personnel registers of the municipalities of Kristiansand, Norway and Aarhus, Denmark were extracted for the years 2004 and 2008, revealing 3498 and 7751 employee-years, respectively. We calculated absence rates together with number of sick leave episodes, and their association with the above-mentioned covariates. Gender-specific comparative descriptive statistics and negative binomial regression analysis were performed.
The sickness absence rate in women was 11.3% in Norway (95% confidence interval [CI] 11.2-11.4) and 7.0% in Denmark (95% CI 7.0-7.1) whereas mean number of sick leave episodes among women was 2.4 in Denmark, compared to 2.3 in Norway (p = 0.02). Young employees in Denmark had more sick leave episodes than in Norway. Proportion of absentees was higher in Denmark compared to Norway (p
PubMed ID
23761933 View in PubMed
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