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Electroencephalographic abnormalities and 5-year outcome in first-episode psychosis.

https://arctichealth.org/en/permalink/ahliterature104119
Source
Can J Psychiatry. 2014 May;59(5):285-8
Publication Type
Article
Date
May-2014
Author
Rahul Manchanda
Ross Norman
Ashok Malla
Rajendra Harricharan
Sandra Northcott
Julie Richard
Author Affiliation
Director-Prevention and Early Intervention Program for Psychoses (PEPP), London Health Sciences Centre-Victoria Hospital, London, Ontario; Professor of Psychiatry, The University of Western Ontario, London, Ontario.
Source
Can J Psychiatry. 2014 May;59(5):285-8
Date
May-2014
Language
English
Publication Type
Article
Keywords
Adaptation, Psychological
Adolescent
Adult
Child
Comorbidity
Educational Status
Electroencephalography - methods - statistics & numerical data
Female
Follow-Up Studies
Humans
Male
Ontario - epidemiology
Patient Outcome Assessment
Predictive value of tests
Psychiatric Status Rating Scales
Psychotic Disorders - diagnosis - epidemiology - psychology
Social Adjustment
Substance-Related Disorders - diagnosis - epidemiology - psychology
Abstract
To examine the relation of electroencephalographic abnormalities to 5-year outcomes in first-episode psychosis (FEP).
Patients (n = 103) had their baseline electroencephalogram (EEG) classified by modified Mayo Clinic criteria. Symptoms and psychosocial functioning were rated after 5 years of treatment.
Dysrhythmic EEG was associated with persistence in positive and negative symptoms of psychoses and poorer psychosocial functioning at 5-year follow-up, independently of other characteristics, such as duration of untreated illness or premorbid adjustment. A higher percentage of people with comorbid substance use disorder had normal EEG.
Abnormal baseline EEG in FEP is associated with poorer 5-year symptomatic and functional outcome.
PubMed ID
25007282 View in PubMed
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